• 대한화학회지
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• 제31권3호
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• pp.280-286
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• 1987

페나실 치환 벤젠술포네이트류와 피리딘의 반응속도를 아세토니트릴과 메탄올 용매속에서 각각 35, 45, 그리고 $55^{\circ}C$에서 전기전도도법으로 측정하였다. 이탈기 내의 치환기 효과는 치환기의 전자끌기 능력이 클수록 반응이 빨라지므로써 이탈기의 이탈 능력이 반응속도에 직접 영향을 미쳤다. 또한 양성자성 용매인 메탄올과 비양성자성 용매인 아세토니트릴에서의 반응을 비교한 결과 수소결합을 통한 특성 용매화가 작용되고 있음을 알수 있었다. 그러므로 이 반응에서 피리딘이 기질의 카르보닐기에 속도 결정 단계로 첨가되는 메카니즘을 배제시킬수 있었다

• 한국진공학회지
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• 제4권S2호
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• pp.1-7
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• 1995

Cu(400$\AA$)/Polyimide has been mixed with 80 keV Ar+ and N2+from 1.0X1015ions/$\textrm{cm}^2$ to 2.0X1016 ions/$\textrm{cm}^2$. The changes of chemical bond and internal properties of sample are investigated by X-ray photoelectron spectroscopy(XPS). The quantitative adhesion strength is measured by using scratch test. The optimized mixing condition is that Cu/PI is irradiated with 80 keV N2+ at a dose of 1.0X1015 ions/$\textrm{cm}^2$, because N2+ ions can product more pyridine-like moiety, amide group, and tertiary amine moiety which are known as adesion promoters than Ar+.

• 한국산업융합학회 논문집
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• 제4권2호
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• pp.185-191
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• 2001

Diphenylpropylamidophosphate(DPPAP) was synthesized as flame retardant for Expanded Polystyrene(EPS). Structure of DPPAP was investigated by the m, NMR, DSC. We make FR panels with EPS beads which treated with DPPAP and expanded by expand machines. FR panels were used in this study after formation by form machines and then cutting by cutting machines. The following conclusions were obtained: 1. The new synthetic agent was developed without the use of solvent such as pyridine or tertiary amine in the synthesis of DPPAP which served as flame retardant for EPS. 2. The flame retandancy effect of EPS treated with DPPAP was found excellent in LOI tests. 3. The properties of FR EPS panels treated with DPPAP did not difference.

• Bulletin of the Korean Chemical Society
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• 제22권9호
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• pp.958-962
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• 2001

The chiral amine auxiliary mediated stereoselective alkylation reactions of glycinamides 1-6 and 15-17 using phase transfer catalyst (PTC) for liquid-solid extraction are described. The secondary N-(diphenylmethylene) glycinamides 1, 2 and 3 give better selectivities and yields than tertiary N-(diphenylmethylene) glycinamides 4, 5 and 6. Alkylation of the glycinamide 1 and 2 using 18-Crown-6 as a PTC in toluene at $-40^{\circ}C$ gives best selectivities and yields. Alkylations of N-(4-chlorophenylmethylene)glycinamides 15, 16 and 17 under same PTC conditions give $\alpha$, $\alpha-disubstituted$ amino acid derivatives 18, 19 and 20 with low diastereoselectivities.

• 공업화학
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• 제7권2호
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• pp.341-349
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• 1996

폴리우레탄 수지의 염색성을 향상시키기 위하여 염착좌석을 갖는 저분자량의 디올류를 쇄연장제로 활용하였다. 쇄연장제와 폴리올의 종류를 변화시키고, 또한 하드세그멘트 (HS)/소프트세그멘트 (SS) 비율을 변화시키면서 폴리우레탄 수지를 합성하였다. HS/SS가 1.4이고, dimethylolpropionic acld(DMPA), N-butyldiethanolamine(BDEA)를 염착좌석용 쇄연장제(DCE)로 활용한 경우 반응의 불균일성으로 인하여 기계적 물성이 좋지 못하였으며, 특히 에스테르계 폴리올인 poly(butylene/ethylene adipate) glycol(PBEAG)로 합성한 경우 내가수분해성이 현저히 저하되었다. 그러나 DCE로 N-methyldiethanol amine(MDEA)를 사용하고 HS/SS를 1.3으로 조절한 경우 기계적 물성과 염색성이 향상되었으며, MDEA를 선형 쇄연장제(CE)인 1,4-butanediol(1,4-BD)과 에테르형 폴리올인 poly[oxyteramethylene] glycol(PTMG)과 반응시킨 경우 기계적 물성과 내가수분해성이 현저하게 향상되었다. 특히 분자설계적 측면에서 DCE를 HS와 SS내의 배분과 1,6-hexanediol(1,6-HD) 및 neopentylglycol(NPG)과의 공쇄연장으로 초기탄성률, 인장강도, 신장률을 제어 할 수 있음을 알 수 있다.

• 대한약리학회지
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• 제16권2호
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• pp.25-29
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• 1980

Etomidoline ($Nonspa^{\circledR}$), which is chemically related to tertiary amine, is new synthetic antispasmodic agent with analgesic action. Antispasmodic effect of this agent is stronger than hyoscine butylbromide ($Buscopan^{\circledR}$), quaternary amine, and the absorption from intestine is also much higher. This study was undertaken to determine the effect of etomidoline on duodenal motility and other smooth muscles of rabbit. Strips of various isolated smooth muscle, 2 cm long from adult rabbits weighting about 2 kg, were suspended in a muscle chamber containing Tyrode's solution, which was bubbled with oxygen gas, and the temperature of the solution was kept constant at $38^{\circ}C$. After being washed with fresh solution several times the strips of smooth muscle attained constant motility and tonus. Etomidoline and other drugs were added in various concentrations to the chamber. Contractility of the strips was measured by using polygraph (Grass, model 7). The results are as follows: 1) In isolated rabbit atrium etomidoline produces a slight depression of contractility and the rate is also decreased. 2) On the other hand, etomidoline relaxed isolated strips of stomach, duodenal, and detrusor of rabbit. This relaxing effect of etomidoline on isolated duodenal strip of rabbit was not blocked by ${\alpha}$-adrenergic blocking agent, phenoxybenzamine, but by ${\beta}$-adrenergic blocking agent, propranolol. 3) Etomidoline did not exert any effect on isolated aorta, gall bladder, and trigone of rabbit. From the above results, it may be concluded that the relaxing effect of etomidoline on duodenal strip is related ${\beta}$-adrenergic receptor.

• 한국식품영양과학회지
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• 제23권4호
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• pp.704-710
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• 1994

멸치젖 첨가 김치 숙성 중 제2급 및 제3급, 제4급 암모늄 호합물의 함량변화 및 N-nitrosamine 생성에 대해 연구한 결과를 요약하면 다음과 같다. 질산염 질소는 발효 숙성 중 대조구와 멸치 첨가구에서 점차적으로 증가하였으나, 아질산염을 검출한계 미만이었다. 제2급 아민은 발효숙성 중 계속적으로 증가하다가 숙성 60일 이후에 급격히 증가하였다. TMA-N는 발효 중 거의 변화가 없는 반면, TMAO-N는 약간 감소하였다. Betaine-N는 숙성 초기에 상당히 증가한 반면 숙성 60일 이후 감소하였다. Cholin-N는 숙성 초기에 감소하다가 중기에는 증가하였으며, 숙성 말기에는 다시 감소하는 현상을 보였다. Creatinine-N는 발효 숙성 중에 변화가 거의 없었다. N-Nitrosamine은 숙성 초기에 수 $\mu\textrm{g}/kg$에서 $45\mu\textrm{g}/kg$까지 검출되었다. 검출되었다.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3173-3179
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• 2010

New complex $[Mn(II)H_{1.5}L]_2[Mn(II)H_3L]_2(ClO_4)_5{\cdot}3H_2O$ (1), where $H_3L$ is tris {2-(4-imidazolyl)methyliminoethyl} amine (imtren), has been prepared by reacting manganese(II) perchlorate hexahydrate with the imtren ligand in methanol. X-ray crystallographic study revealed that the imtren ligand hexadentately binds to Mn(II) ion through the three Schiff-base imine N atoms and three imidazole N atoms with a distorted octahedral geometry, and the apical tertiary amine N atom of the ligand pseudo-coordinates to Mn(II), forming overall a pseudo-seven coordination environment. The hydrogen-bonds between imidazole and imidazolate of $[Mn(II)H_{1.5}L]^{0.5+}$ complex ions are extended to build a 2D puckered network with trigonal voids. $[Mn(II)H_3L]^{2+}$ complex ions constitutes another extended 2D puckered layer without hydrogen bonds. Two layers are wedged each other to constitute overall stack of the crystal. Peroxidase activity of complex 1 was examined by observing the oxidation of 2,2'-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) with hydrogen peroxide in the presence of complex 1. Generation of $ABTS^{+{\cdot}}$ was observed by UV-vis and EPR spectroscopies, indicating that the complex 1, a fully-coordinated mononuclear Mn(II) complex with nitrogen-only ligand, has a heme-independent peroxidase activity.

• 자원리싸이클링
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• 제28권1호
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• pp.55-61
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• 2019

묽은 염산용액의 pH를 2에서 9까지 변화시켜 아민계(Alamine 308과 TEHA)와 중성추출제(TOP)로 몰리브덴(VI)과 텅스텐(VI)의 용매추출거동을 조사하였다. 텅스텐(VI)이 몰리브덴(VI)보다 상기 세 추출제에 선택적으로 추출되었으며, TEHA로 추출시 가장 높은 분리인자를 얻었다. 수소화처리하지 않은 3차 아민에 의한 두 금속의 추출율은 용액의 pH에 따라 지속적으로 감소하여 pH 9에서는 전혀 추출되지 않았다. 본 논문의 실험조건에서 용매추출거동을 금속의 농도분포곡선을 이용하여 설명하였다. Alamine 308과 TEHA는 TOP에 비해 두 금속의 추출과 분리에 효과적이다.

• 상하수도학회지
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• 제32권3호
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• pp.279-289
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• 2018

N-nitrosodimethylamine (NDMA) is a class of disinfection byproducts and a frequently detected nitrosamine with carcinogenic potentials. This review summarizes NDMA precursors, their formation mechanisms in chloraminated water, and mitigation strategies. Understanding the formation mechanism and characteristics of precursors is essential for developing a mitigation strategy. Dimethylamine (DMA), the most widely studied NDMA precursor, has an NDMA molar yield up to 3%. In comparison, a subset of tertiary amines, e.g., pharmaceuticals, generate up to 90% upon chloramination. Potent NDMA precursors, are characterized by their negative partial charge, low planarity values and molecular weight, and high bond length and $pK_a$ values. A nucleophilic substitution of tertiary amine on chloramine is a key reason for the high NDMA yield from the most potent NDMA precursors. The distribution and fate of NDMA in surface water, aquifers, and its formation in the distribution system can be mitigated through two strategies: (1) degrading or/removing NDMA after its formation and (2) pre-treatment of its precursor's prior chloramination.