• Journal of Preventive Medicine and Public Health
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• 제33권4호
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• pp.402-408
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• 2000

Objectives : To investigate possible seasonal patterns of pre-term birth in Korea. Methods : A total number of 2,669,357 single live births reported to the National Statistical Office from 1995 to 1998 were analyzed. Composite monthly cohorts of ongoing pregnancies were constructed for each month of the year and the probability of pre-term birth was estimated. Results : Increases in the probability of a pre-term birth occurred during winter for the birth of first child and during summer for the birth of second or later child. This seasonal variation was similar among groups divided by sex, residency, age of mother, and education of mother. Conclusions : These findings suggests that some environmental factors related to season may partially explain the incidence of premature births.

• IEIE Transactions on Smart Processing and Computing
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• 제4권2호
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• pp.103-109
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• 2015

In this paper, a novel method for the classification of term and preterm birth is proposed based on time-frequency analysis of electrohysterogram (EHG) using multivariate empirical mode decomposition (MEMD). EHG is a promising study for preterm birth prediction, because it is low-cost and accurate compared to other preterm birth prediction methods, such as tocodynamometry (TOCO). Previous studies on preterm birth prediction applied prefilterings based on Fourier analysis of an EHG, followed by feature extraction and classification, even though Fourier analysis is suboptimal to biomedical signals, such as EHG, because of its nonlinearity and nonstationarity. Therefore, the proposed method applies prefiltering based on MEMD instead of Fourier-based prefilters before extracting the sample entropy feature and classifying the term and preterm birth groups. For the evaluation, the Physionet term-preterm EHG database was used where the proposed method and Fourier prefiltering-based method were adopted for comparative study. The result showed that the area under curve (AUC) of the receiver operating characteristic (ROC) was increased by 0.0351 when MEMD was used instead of the Fourier-based prefilter.

• 식품보건융합연구
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• 제5권2호
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• pp.1-11
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• 2019

The objective of this study is to assess the effect of interpregnancy interval on fetal outcome among women with term premature rupture of membrane in public hospitals, Ethiopia, 2017. Facility based follow up study was conducted in Southern Ethiopia public hospitals from February 30, 2017 to August 20, 2017. Among 150 observed mothers with interpregnancy interval of less two years, 46.67 % (95% CI: (7.170, 29.93) of them experienced adverse birth outcome, but among 173 women with interpregnancy interval of two and above years, 5.78% (95% CI: (7.170, 29.93) of them experienced adverse birth outcome. The odds of adverse birth outcome were more among women with interpregnancy interval of less than two years (AOR=17.899, 95%CI: [6.425, 49.859]. The effect of interbirth interval of less than two years on adverse birth outcome of newborn was increased by length labor of >=24 hours, induction of labour and cesarean section delivery. Interpregnancy interval of less than two years, in collaboration with other risk factors, is the main predictor of adverse birth outcome. Therefore especial attention should be given to mothers with birth spacing by using family planning methods to reduce adverse birth outcome.

• Clinical and Experimental Pediatrics
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• 제49권1호
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• pp.14-17
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• 2006

Infants who are born prematurely or with low birth weight should be immunized at the same postnatal chronologic age. They should receive BCG, DTaP, IPV vaccines according to the same recommended schedule as full term infants. Hepatitis B vaccine schedule is modified when hepatitis B vaccine is administered a infant with birth weight less than 2,000 g. The recommended standard dose of each vaccine should be administered. Proportion of children experiencing vaccine-related adverse events dose not differ between full-term and preterm infants. Immunization with routinely recommended childhood vaccines is safe for preterm and low birth weight infants.

• Child Health Nursing Research
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• 제21권4호
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• pp.339-346
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• 2015

Purpose: This study was performed to explore the weight variations in high-risk term newborns hospitalized during the early postnatal period. Methods: A retrospective explorative study was performed with 64 term newborns who were hospitalized in the NICU after birth. Data on daily weight, birth information, and clinical features such as phototherapy, placements, nutritional status were reviewed through medical records for 14 days of life. General Linear Model, GLM was applied to analyze the weight variation by clinical features of these high-risk term newborns for 14 days of life. Results: Newborns at 40 weeks of gestation showed little weight loss during the few days after birth then steadily gained weight to 7.6% at the 14th day. Infants born at 37-39 gestation showed little weight gain for 14 days though the weight loss itself was not apparent. As well, return to birthweight was not observed in newborns with phototherapy, infants placed on a warmer or infants having gastrointestinal dysfunction for 14 days of life. Conclusion: Even for term newborns, physiologic weight loss may not be warranted even if newborn is born at less than 40 week of gestation, or with high-risk conditions that warrant admission to NICU.

• 대한한방소아과학회지
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• 제15권2호
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• pp.31-41
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• 2001

We studied 100 neonates to enter a Dongguk University Oriental Hospital Postpartum Care Center, during 9 months from February 10. 2001 to November 4. 2001. The conclusion is following. 1. Newborn sex ratio was 1.70. 2. Delivery method : Normal vaginal delivery was 66 and cesarean section was 34. 3. Gestation age : Premature infants less than 37 weeks were 2 term infants from 37 to 41 weeks were 98 and post-term infants 42 or more weeks were zero. 4. Period between birth and admission : First to fifth day was 66 sixth to tenth day was 32 and eleventh or more day was 2. 5. Period of admission : 1 to 7 days were 8. 8 to 14 days were 65. 15 to 21 days were 23. and 22 to 28 days were 4. 6. Weight : Birth weight less than 2500g was 3. 2500 to 3999g was 92. and 4000g or more was 5. 7. Height : Zero week after birth the average height was 48.8cm, one week after birth was 50.0cm, two weeks after birth was 51.8cm, three weeks after birth was 53.2cm, four weeks after birth was 54.5cm. 8. Head circumference : Zero week after birth the average head circumference was 34.6cm, one week after birth was 35.3cm, two weeks after birth was 35.7cm, three weeks after birth was 36.3cm, four weeks after birth was 36.8cm. 9. Chest circumference : Zero week after birth the average chest circumference was 33.2cm, one week after birth was 33.5cm, two weeks after birth was 34.4cm, three weeks after birth was 35.1cm, four weeks after birth was 36.6cm. 10. Feeding : There was not breast feeding, artificial feeding was 8, and mixing feeding was 92. 11. Jaundice : Physiologic jaundice was 10, pathologic jaundice was 1.

• 부모자녀건강학회지
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• 제8권2호
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• pp.147-156
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• 2005

Purpose: The purpose of this study was the influencing variables of maternal weight gain and neonatal birth weight in full term pregnancies. Method: The subjects were 136 mothers in full term pregnancies(38-42 weeks) and her babies who were selected from 2 general hospital in Pusan. The data were collected from June 14th to October 14th in 2004. Data were obtained by questionnaires. Results: The maternal weight gains was lesser that the pregravid weights was the lower (F=3.410, p=.011). The volumes of weight gains of mothers that had alcohol drinking(t=6.259, p=.014), caffeine consumption (t=4.137, p=.044) were lesser than not. And the birth weight were influenced by passive smoking(t=4.017, p=.047), caffeine consumption (t=5.954, p=.016). Conclusion: The results of this research confirm that the maternal weight gains were influenced by pregravid weight, alcohol drink, caffeine consumption. And the birth weight were influenced by passive smoking, caffeine consumption.

• Clinical and Experimental Pediatrics
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• 제63권2호
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• pp.56-62
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• 2020

Background: Red blood cell (RBC) transfusion improves cardiorespiratory status of preterm infants by increasing circulating hemoglobin, improving tissue oxygenation, and reducing cardiac output. However, RBC transfusion itself has also been suggested to negatively affect short-term outcomes such as intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), and necrotizing enterocolitis (NEC) in premature infants. Purpose: This study aimed to analyze the relationship between RBC transfusion and short-term outcomes in very low birth weight (VLBW) infants (birth weight, <1,500 g). Methods: We retrospectively reviewed the medical records of VLBW infants admitted to the Soonchunhyang University Bucheon Hospital between October 2010 and December 2017. Infants who died during hospitalization were excluded. The infants were divided into 2 groups according to RBC transfusion status. We investigated the relationship between RBC transfusion and short-term outcomes including BPD, ROP, NEC, and IVH. Results: Of the 250 enrolled VLBW infants, 109 (43.6%) underwent transfusion. Univariate analysis revealed that all short-term outcomes except early-onset sepsis and patent ductus arteriosus were associated with RBC transfusion. In multivariate analysis adjusted for gestational age, birth weight and Apgar score at 1 minute, RBC transfusion was significantly correlated with BPD (odds ratio [OR], 5.42; P<0.001) and NEC (OR, 3.40; P= 0.009). Conclusion: RBC transfusion is significantly associated with adverse clinical outcomes such as NEC and BPD in VLBW infants. Careful consideration of the patient's clinical condition and appropriate guidelines is required before administration of RBC transfusions.

• Neonatal Medicine
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• 제16권1호
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• pp.36-46
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• 2009

목적 : 본 저자들은 국내 57개 병원을 대상으로 2007년 한 해 동안 원내출생아의 특성과 분포 및 신생아 중환자실 입원 환자의 특성과 분포, 그리고 사망률을 조사하였다. 방법 : 2008년 3월 신샹아 중환자실을 갖춘 곳 중 전국 57개 개 병원으로부터 2007년 한해 동안 발생하였던 신생아 출생 및 사망에 관한 설문을 보내고 회신을 받아 그 결과를 분석하였다. 그 내용에는 1) 원내 총 출생아의 재태기간별, 출생체중별 분포, 2) 신생아중환자실 입원 환자의 재태기간별, 출생체중별 분포 및 사망률이 포함되어 있었으며, 이 결과를 1996년 및 2002년에 조사되었던 한국의 결과와 비교하였다. 결과 : 총 40,433의 신생아 원내출생이 57개 병원으로부터 조사되었으며, 미숙아, 만삭아, 과숙아는 각각 24.2%, 75.6%, 0.2%의 출생빈도를 차지하였다. 또한, 저체중 출생아, 정상체중아, 과체중아는 각각 22.0%, 74.6%, 3.4%로 조사되었는데, 특히 국소 저체중출생아와 초극소 저체중출생아는 각각 4.6%와 1.7%이었다. 2007년 한 해 동안 전국 57개 병원의 신생아 중환자실에서 입원치료를 받은 환자의 분포를 보면, 재태기간에 따라 조사된 총 인원수는 21,957명, 출생체중에 따라 조사된 총 인원수는 21,356명으로 조사되었다. 이들의 사망률은 미숙아, 만삭아, 과숙아에서 가각 4.5%, 0.7%, 3.7%이었고, 특히 재태기간 32주 미만에서는 11.3%, 보다 작은 재태기간 28주 미만에서는 26%의 높은 사망률을 보이고 있었다. 1996년과 2002년의 국내 자료와 비교하여 보면, 미숙아, 저체중출생아, 초극소 저체중출생아의 출생수는 현저히 증가하고 있었으며, 이들의 사망률은 감소하는 양상을 확인할 수 있었다. 결론 : 본 저자들은 과거 1996년과 2002년의 국내 조사 결과와 2007년의 본 연구 결괄ㄹ 비교해 보았을 때 미숙아, 저체중출생아와 초극소 저체중츨생아의 빈도가 증가하고 있으며, 이들의 사망률은 현저히 감소하고 있음을 확인하였다. 비록 한국 미숙아 진료의 결과가 개선되고 있는 것으로 조사되었으나, 아직도 초미숙아의 사망률은 높기 때문에 이들의 치료에 보다 많은 노력을 기울여야 할 것으로 생각된다.

• Neonatal Medicine
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• 제25권4호
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• pp.137-143
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• 2018

Purpose: This study was performed to determine the clinical features of full-term infants with hypoxemia detected by pulse oximetry and to establish the diagnosis of critical congenital heart disease (CCHD). Methods: We retrospectively reviewed the medical records of neonates who had been admitted to the neonatal intensive care unit within 2 weeks of birth at Korea University Ansan Hospital between January 2013 and October 2017 (n=450). We classified these neonates based on the presence of hypoxemia at admission and investigated neonatal characteristics, initial symptoms, echocardiographic findings, and final diagnosis associated with hypoxemic diseases. Results: Of 450 term infants, 265 infants (58.9%) were identified hypoxemia by pulse oximetry at admission. The most common symptoms of them were cyanosis and tachypnea. Among them, 80.1% of infants (214/265) were diagnosed with respiratory tract disease and 8.3% of infants (22/265) had congenital heart disease. Thirteen infants (13/265, 4.9%) had CCHD and were treated with urgent surgery or transcatheter intervention within 28 days of birth. Majority of infants with respiratory tract disorder were transferred from hospital immediately after birth, but 46.1% of infants (6/13) with CCHD remained asymptomatic after birth and were admitted after 48 hours after birth. In addition, other hypoxemic illnesses were identified as neonatal infectious and neurological diseases. Conclusion: This study showed the importance of assessment in neonates with hypoxemia, including those diagnosed with CCHD. The possibility of CCHD should be considered in the differential diagnosis in neonates demonstrating hypoxemia after 48 hours of birth. A larger prospective study is needed to assess the effectiveness and outcomes of pulse oximetry for neonatal screening in Korea.