• 제목/요약/키워드: Temperature stability time

검색결과 874건 처리시간 0.036초

사물탕 전탕액의 보관 조건에 따른 안정성 분석 (Effect of Preservation Conditions on the Stability of Samul-tang Decoctions)

  • 박인화;김연학;최성환;유선녕;김상헌;안순철;조수인;이인
    • 생명과학회지
    • /
    • 제25권10호
    • /
    • pp.1124-1131
    • /
    • 2015
  • 본 연구를 통해 보관 조건에 따른 사물탕 전탕액의 유효활성 물질 및 안정성과 관련된 특성들의 경시적 변화를 관찰하였다. 사물탕 전탕액의 보관온도(냉동 조건, 냉장 조건, 상온 암 조건, 상온 빛 조건, 고온 조건)를 달리하여, 각각을 0, 15, 30, 90, 180일간 보관하였다. 사물탕 전탕액의 경시적 변화로는 육안적 관찰, 산도, 흡광도, high performance liquid chromatography (HPLC) 분석, 생리활성(tyrosinase 저해 활성), 세균학적 검사 등을 관찰하였다. 그 결과, 사물탕 전탕액의 다양한 보관 기간과 온도에서, 육안적 검사, 산도, 흡광도, HPLC분석, 생리활성에서 경시적으로 큰 변화가 없었으며, 세균학적 검사를 통해서는 세균이 검출되지 않았다. 그러나 그 변화의 차이는 크지 않았지만, 사물탕 전탕액의 보관조건이 악화될수록, 보관기간이 증가할수록 미세한 변화가 관찰되었다. 따라서 6개월 이상 장기간 보관 할 경우, 사물탕 전탕액을 상온 암 조건, 상온 빛 조건, 고온 조건에서 보다 냉동 혹은 냉장 조건이나 가능하면 어두운 곳에서 보관하는 것이 유효성분 및 활성의 변화나 전탕액의 변질을 방지하기 위한 보관법으로 판단되었다.

얇은 절연막의 TDDB 분석과 전기적 특성 (TDDB Analysis and Electrical Characteristics of Thin Insulator Films)

  • 박찬원;김복헌
    • 산업기술연구
    • /
    • 제8권
    • /
    • pp.23-30
    • /
    • 1988
  • In this paper, the characteristics of electrical breakdown and TDDR (Time Dependant Dielectric Breakdown) were studied to evaluate stability and reliability of thin insulator films such as oxide and nitride. As the oxide film thickness decreased, the electrical breakdown field was increased proportioning to its reverse square root, ${d^{-\frac{1}{2}}}$. As for the temperature dependance of breakdown field, its field was inclined to decrease as temperature increased. It also showed that oxide charge (Qss) was changed by stress field and stress time. Consequently, TDDB characteristics and breakdown mechanism proved the improvement of reliability and stability and provided the accurate analysis to predict a device life time.

  • PDF

Evaluation on the stability of Vitamin preparations- Vitamin A

  • Kim, Mi-Jeong;Chang, Sung-Jae;Choi, Don-Woong;Kim, Hee-Sung;Chang, Soo-Hyun;Jung, Ki-Sook;Kim, Ji-Ha;Choi, Jong-Won;Chang, Seung-Yeup
    • 대한약학회:학술대회논문집
    • /
    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
    • /
    • pp.302.1-302.1
    • /
    • 2003
  • Accelerated stability testing was performed on the different 7 dosage forms in order to evaluate the influences of the existence of other vitamins, minerals, excipients on the chemical stability of vitamin A in complicated vitamin drug products. The stability results suggested that increasing of storage time and temperature has resulted in increasing the rate of vitamin A decomposition and the shelf lives(t$\sub$90/) under the test decreased as the storage temperature increased. (omitted)

  • PDF

알칼리 수전해를 위한 상용 음이온교환막의 고온 특성 (High Temperature Characteristics of Commercially Available Anion Exchange Membrane for Alkaline Water Electrolysis)

  • 장수연;유철휘;황갑진
    • 한국수소및신에너지학회논문집
    • /
    • 제33권4호
    • /
    • pp.330-336
    • /
    • 2022
  • In order to evaluate the possibility as a separator in alkaline water electrolysis, the high temperature characteristics were evaluated by measuring the membrane resistance and durability of 5 types of commercial anion exchange membranes in 7 M KOH solution and at 80℃. The membrane resistance of AEM membrane measured in 7 M KOH solution and at 80℃ had a lower value of about 8-24 times compared to the other membranes. The durability of AEM membrane tested with the soaking time in 7 M KOH solution and at 80℃ showed a very good stability and that of FAAM40 and FAAM75-PK showed secondly a good stability. The thermal stability with the soaking time in 7 M KOH solution and at 80℃ of FAAM40 and FAAM75-PK membrane analyzed by thermo-gravimetric analysis showed a good stability compared to the other membranes.

환경 및 신뢰성 시험분야를 위한 숙련도시험 시료개발 연구 (A Study on Proficiency Test Sample Development for Environmental & Reliability Testing Field)

  • 박경환;이철규
    • 품질경영학회지
    • /
    • 제45권3호
    • /
    • pp.447-462
    • /
    • 2017
  • Purpose: This study aims to develop distributable samples that can be used for proficiency testing to verify the ability of the testing laboratory to perform high temperature and low temperature tests. Method: In this study, the temperature-resistance characteristics of the NTC thermistor were used to develop samples. The homogeneity and stability of samples were examined according to the proficiency testing requirements. Results: Thirty samples with homogeneity and stability were developed and used for the proficiency testing. Thus, it was possible to distinguish between the test laboratories that showed satisfactory results and those that did not. Conclusion: It was the first time to develop samples that can be used for proficiency testing in high temperature and low temperature tests. and it was proved that the proficiency test program can be operated using the characteristics of NTC thermistor.

치과용 임플란트의 안전성과 유효성에 대한 드릴 디자인의 효과 (The effect of drill design on stability and efficacy of dental implants)

  • 윤지훈;전계록;윤미정;허중보;정창모
    • 대한치과의사협회지
    • /
    • 제53권2호
    • /
    • pp.132-142
    • /
    • 2015
  • Purpose : The objective of this research was to investigate an optimization of drill design factors for implant stability and efficacy through comparative evaluation by the cutting time, heat generation and initial stability. Materials and Methods : Three design factors were considered for the purpose of drill design optimization; the number of flute(2 flute, 3 flute), helix angle($15^{\circ}$, $25^{\circ}$) and drill tip shape(straight, 2-phase). Design factors were selected through comparative evaluation by temperature change, cutting time and ISQ value. Results : Heat generation and cutting time are influenced by all design factors(p<0.05). Drill tip shape was the only factors which influenced to the largest initial stability(p<0.05). Conclusion : Drills with 2 flutes, 2-phase formed drill tip, and 25 degrees of helix angle exhibit a better performance than other design.

A study on charging and electrical stability characteristics with no-insulation and metal insulation in form of racetrack type coils

  • Quach, Huu Luong;Kim, Ho Min
    • 한국초전도ㆍ저온공학회논문지
    • /
    • 제22권3호
    • /
    • pp.13-19
    • /
    • 2020
  • This study presents the experiment and simulation results on the magnetic field response and electrical stability behaviors of no-insulation (NI) and metal insulation with stainless steel tape (MI-SS) which wound in form of racetrack type coils. First of all, the structural design of the racetrack type bobbin was shown along with its parameters. Then, the current-voltage tests were carried out to measure the critical current of both test coils. Also, the sudden discharging and charging tests were performed in the steady state to estimate the decay field time and magnetic field response, respectively. Finally, the overcurrent tests were conducted in the transient state to investigate the electrical stability of these test coils. Based on the experimental results, the contact surface resistances were calculated and applied to the field coils (FCs) of 10-MW-class second generation high temperature superconducting generator (2G HTSG) used in wind offshore environment. The charging delay time and electrical stability for NI and MI-SS HTS FCs of 10-MW-class 2G HTSG are analyzed by the equivalent circuit model and the key parameters which were obtained from the electromagnetic finite element analysis results.

스팀-에어 레토르트의 온도분포에 미치는 공정 변수 영향 (The Effect of Various Processing Conditions on Temperature Distribution in Steam-air Retort)

  • 이선영;신해헌;인예원;조형용
    • 산업식품공학
    • /
    • 제23권2호
    • /
    • pp.87-93
    • /
    • 2019
  • 공기 주입식 스팀-에어 레토르트 내에서 스팀온도, 내부가압, CUT 등의 공정변수가 레토르트 내부의 온도 균일성에 미치는 영향을 평가하였다. 고온살균(121℃)이 저온살균(82℃) 보다 공정구간동안 온도분포가 더 균일하고 안정적이었다. 내부 가압이 클수록 저온살균조건의 공정에서는 온도분포가 안정적이었고, 이와 반대로 고온살균조건의 공정에서 온도분포가 더 불균일한 것으로 나타났다. 승온구간을 조절한 경우에는 레토르트 내의 온도분포에는 유의적인 차이를 나타내지 않았다. 공정구간동안 레토르트 내부에서 냉점은 수직방향 1층의 위로 확인되었고, 수평방향에서는 맨 뒤쪽 중앙 부분이 가장 높은 온도를 유지하여 공정 동안 이 위치들을 주의를 할 필요가 있었다. 또한 레토르트 내부의 양 옆 위치가 다른 위치에 비해 특히 온도분포가 불안정한 것으로 확인되었으므로 레토르트 가공 공정에서 주의해야 할 것으로 판단되었다.

트리할로스, 포도당 및 유당이 한탄바이러스 백신의 안정성에 미치는 영향 (Effects of Trehalose, Glucose and Lactose on the Stability of Hantaan Virus Vaccine)

  • 고은주;성인화
    • 대한바이러스학회지
    • /
    • 제29권4호
    • /
    • pp.211-219
    • /
    • 1999
  • Most of the currently licensed viral and bacterial vaccines produced in the world are in state of antigen suspension and the immunogenicity of vaccines could be maintained for one or two years only by keeping in the refrigerator, but without refrigeration vaccines would easily lose their immunogenicites. In this study, as a step to develope the method of increasing the stability of vaccines and maintaining the immunogenicity of vaccines for a long time at room temperature or higher temperature, trehalose, glucose and lactose at different concentration were added into the Hantaan virus vaccines and then kept at $37^{\circ}C$ for 12, 24, 48 hours and at room temperature for seven days respectively. Treated vaccines were then inoculated respectively into ICR mice and the titers of antibody against the antigen of Hantaan virus from the mice sera were evaluated. Vaccine without sugar lost immunogenicity completely in 24 hour at $37^{\circ}C$, but the vaccines containing trehalose could maintain some of the immunogenicity even after exposure at $37^{\circ}C$ for 48 hours and the best concentration of trehalose for maintaining the immunogenicities of vaccines was $7.5{\sim}10$ percent. The results suggest that addition of trehalose could increase the stability of Hantaan virus vaccine.

  • PDF

IDLE PERFORMANCE OF AN SI ENGINE WITH VARIATIONS IN ENGINE CONTROL PARAMETERS

  • Kim, D.S.;Cho, Y.S.
    • International Journal of Automotive Technology
    • /
    • 제7권7호
    • /
    • pp.763-768
    • /
    • 2006
  • Emission reduction in the cold start period of SI engines is crucial to meet stringent emission regulations such as SULEV Emissoin reduction is the starting point of the study in the which the variable valve timing (VVT) technology may be one promising method to minimize cold start emissions while maintaining engine performance. This is because it is possible to change valve overlap and residual gas fraction during cold start and idle operations. Our previous study showed that spark timing is another important factor for reducing cold-start emissions since it affects warm-up time of close-coupled catalysts (CCC) by changing exhaust gas temperature. However, even though these factors may be favorable for reduction of emissions, they may deteriorate combustion stability in these operating conditions. This means that the two variables should be optimized for best exhaust emissions and engine stability. This study investigated the effects of valve and spark timings in idle performance such as combustion stability and exhaust emissions. Experiments showed that valve timings significantly affected engine stability and exhaust emissions, especially CO and $NO_x$, due to change in residual gas fraction within the combustion chamber. Spark timing also affects HC emissions and exhaust gas temperature. Yet it has no significant effects on combustion stability. A control strategy of proper valve timing and spark timing is suggested in order to achieve a reduction in exhaust emissions and a stable operation of the engine in a cold start and idle operation.