• Journal of People, Plants, and Environment
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• v.21 no.6
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• pp.485-492
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• 2018

This study aimed to develop and validate highly sensitive determination method of a prostaglandin ($PGE_1$, OP 1206) in human plasma by LC-MS/MS using column switching. Plasma stored at $-30^{\circ}C$ and treated with methanol effectively inhibited interferences synthesized post-sampling. Samples were added with internal standard and were separated by reversed-phase HPLC with a cycle time of 30min. The method was selective for OP 1206 and the regression models, based on internal standard, were linear across the concentration range 0.5-50 pg/mL with the limit of quantification of 0.5 pg/mL (limit of quantitation, LOQ) for OP 1206. The calibration curve of OP 1206 standards spiked in five individual plasma samples was linear ($r^2=0.9999$). Accuracy and precision at the concentrations of 0.5, 1.5, 5.0 and 40 pg/mL, and at the lower LOQ of 0.5 pg/mL were excellent at 20%. OP120 < 6 was stable in plasma samples for at least 24 hours at room temperature, 24 hours frozen at $-70^{\circ}C$, 24 hours in an auto sampler at $6^{\circ}C$, and for two freeze/unfreezing cycles. The validated determination method successfully quantified the concentrations of OP 1206 in plasma samples from simulated administrating a single $5{\mu}g$ OP 1206 formulation. Thus, this novel LC-MS/MS technique for drug separation, detection and quantitation is expected to become the standard highly-sensitive detection method in bioanalysis and to be applied to many low dose pharmaceutical products.

• Transactions of Materials Processing
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• v.27 no.6
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• pp.370-378
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• 2018

Cold forging, carried out at room temperature, leads to high dimensional accuracy and excellent surface integrity as compared to other forging methods such as warm and hot forgings. In the cold forging process, WC-Co (Tungsten Carbide-Cobalt) alloy is the mainly used material as a core dies because of its superior hardness and strength as compared to other structural materials. For cold forging, die life is the most significant factor because it is directly related to the manufacturing cost due to periodic die replacement in mass production. To investigate die life of WC-Co alloy for cold forging, mechanical properties such as strength and fatigue are essentially necessary. Generally, uniaxial tensile test and fatigue test are the most efficient and simplest testing method. However, uniaxial tension is not efficiently application to WC-Co alloy because of its sensitivity to alignment of the specimen due to its brittleness and difficulty in thread machining. In this study, shape of specimen, tools, and testing methods, which are appropriate for uniaxial tensile test for WC-Co alloy, are proposed. The test results such as Young's modulus, tensile strength and stress-strain curves are compared to those in previous literature to validate the proposed testing methods. Based on the validation of test results it was concluded that the newly developed testing method is applicable to other cemented carbides like Titanium carbides with high strength and brittleness, and also can be utilized to carry out fatigue tests for further investigation on die life of cold forging.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.6
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• pp.555-563
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• 2018

Thermal infrared images have the characteristic of being able to detect objects that can not be seen with the naked eye and have the advantage of easily obtaining information of inaccessible areas. However, TIR (Thermal InfraRed) images have a relatively low spatial resolution. In this study, the applicability of the pansharpening algorithm used for satellite imagery on images acquired by the UAV (Unmanned Aerial Vehicle) was tested. RGB image have higher spatial resolution than TIR images. In this study, pansharpening algorithm was applied to TIR image to create the images which have similar spatial resolution as RGB images and have temperature information in it. Experimental results show that the pansharpening algorithm using the PC1 band and the average of RGB band shows better results for the quantitative evaluation than the other bands, and it has been confirmed that pansharpening results by ATWT (${\grave{A}}$ Trous Wavelet Transform) exhibit superior spectral resolution and spatial resolution than those by HPF (High-Pass Filter) and SFIM (Smoothing Filter-based Intensity Modulation) pansharpening algorithm.

• Korean Journal of Remote Sensing
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• v.35 no.1
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• pp.57-81
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• 2019

Satellite images can be integrated into a crop model to strengthen the advantages of each technique for crop monitoring and to compensate for weaknesses of each other, which can be systematically applied for monitoring inaccessible croplands. The objective of this study was to outline the productivity of paddy rice based on simulation of the yield of all paddy fields in North Korea, using a grid crop model combined with optical satellite imagery. The grid GRAMI-rice model was used to simulate paddy rice yields for inaccessible North Korea based on the bidirectional reflectance distribution function-adjusted vegetation indices (VIs) and the solar insolation. VIs and solar insolation for the model simulation were obtained from the Geostationary Ocean Color Imager (GOCI) and the Meteorological Imager (MI) sensors of the Communication Ocean and Meteorological Satellite (COMS). Reanalysis data of air temperature were achieved from the Korea Local Analysis and Prediction System (KLAPS). Study results showed that the yields of paddy rice were reproduced with a statistically significant range of accuracy. The regional characteristics of crops for all of the sites in North Korea were successfully defined into four clusters through a spatial analysis using the K-means clustering approach. The current study has demonstrated the potential effectiveness of characterization of crop productivity based on incorporation of a crop model with satellite images, which is a proven consistent technique for monitoring of crop productivity in inaccessible regions.

• Journal of Advanced Navigation Technology
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• v.23 no.2
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• pp.172-178
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• 2019

This paper has designed, fabricated, and analyzed the passive devices realized using low temperature co-fired ceramic (LTCC) multi layer substrates by dividing into the shrinkage process and the non-shrinkage process. Using two types of ceramic materials with dielectric constant 7 or 40, we have fabricated the same shape of various elements in 2 different processes and compared the characteristics. For the substrate of dielctric constant 40, compared with the shrinkage process which has 17% shrink in the X and Y directions with 36% shrink in the Z direction, the non-shrinkage process has 43% shrink in the Z direction without shrink in the X and Y directions, so high dimensional accuracy and surface flatness can be obtained. The inductances and capacitances of the fabricated elements are estimated from measurement using empirical analysis equations of parameters and implemented as a design library. Depending on the substrate and the process, the inductance and capacitance depending on the turn number of winding and unit area have been measured, and empirical polynomials are proposed to predict element values.

• Journal of Ocean Engineering and Technology
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• v.35 no.2
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• pp.141-149
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• 2021

The A60 class deck penetration piece is a fire-resistance apparatus installed on the deck compartment to protect lives and to prevent flame diffusion in the case of a fire accident in a ship or offshore plant. In this study, the sensitivity of the fire-resistance performance and approximation characteristics for the A60 class penetration piece was evaluated by conducting a transient heat-transfer analysis and fire test. The transient heat-transfer analysis was conducted to evaluate the fire-resistance design of the A60 class deck penetration piece, and the analysis results were verified via the fire test. The penetration-piece length, diameter, material type, and insulation density were used as the design factors (DFs), and the output responses were the weight, temperature, cost, and productivity. The quantitative effects of each DF on the output responses were evaluated using the design-of-experiments method. Additionally, an optimum design case was identified to minimize the weight of the A60 class deck penetration piece while satisfying the allowable limits of the output responses. According to the design-of-experiments results, various approximate models, e.g., a Kriging model, the response surface method, and a radial basis function-based neural network (RBFN), were generated. The design-of-experiments results were verified by the approximation results. It was concluded that among the approximate models, the RBFN was able to explore the design space of the A60 class deck penetration piece with the highest accuracy.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.3
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• pp.429-436
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• 2021

The wind profilers operated by the Korea Meteorological Administration observe in a low mode for intensive observation of the low levels and a high mode for intensive observation of the high levels. The LAP-3000 wind profiler installed in Bukgangneung and Changwon is characterized by the same sampling frequency of the low mode and the high mode, allowing to compare winds observed in both modes at the same altitude. As a result of analyzing the wind speed of the two points for one year in 2020, the correlation between the two modes was up to 0.2 lower than the correlation with radiosonde. The T-test for the wind speed of the two modes showed a particularly significant difference in October, where the temperature and specific humidity fluctuate frequently. The difference in the development of the atmospheric boundary layer affects the accuracy of the wind speed depending on the observation mode.

• Journal of Korean Society on Water Environment
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• v.35 no.5
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• pp.425-431
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• 2019

Recently, people have been attracting attention to the good quality of water resources as well as water welfare. to improve the quality of life. This study is a papers on the prediction of benthic macroinvertebrate index (BMI), which is a aquatic ecological health, using the machine learning based CFS (Correlation-based Feature Selection) method and the random forest model to compare the measured and predicted values of the BMI. The data collected from the Han River's branch for 10 years are extracted and utilized in 1312 data. Through the utilized data, Pearson correlation analysis showed a lack of correlation between single factor and BMI. The CFS method for multiple regression analysis was introduced. This study calculated 10 factors(water temperature, DO, electrical conductivity, turbidity, BOD, $NH_3-N$, T-N, $PO_4-P$, T-P, Average flow rate) that are considered to be related to the BMI. The random forest model was used based on the ten factors. In order to prove the validity of the model, $R^2$, %Difference, NSE (Nash-Sutcliffe Efficiency) and RMSE (Root Mean Square Error) were used. Each factor was 0.9438, -0.997, and 0,992, and accuracy rate was 71.6% level. As a result, These results can suggest the future direction of water resource management and Pre-review function for water ecological prediction.

• Computers and Concrete
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• v.26 no.6
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• pp.467-482
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• 2020

This research focused on analyzing the post-fire behavior of high-performance concrete-filled steel tube (CFST) columns, with the concrete containing tire rubber and steel fibers, under axial compressive loading. The finite element (FE) modeling of such heated columns containing recycled aggregate is a branch of this field which has not received the proper attention of researchers. Better understanding the post-fire behavior of these columns by measuring their residual strength and deformation is critical for achieving the minimum repair level required for structures damaged in the fire. Therefore, to develop this model, 19 groups of confined and unconfined specimens with the variables including the volume ratio of steel fibers, tire rubber content, diameter-to-thickness (D/t) ratio of the steel tube, and exposure temperature were considered. The ABAQUS software was employed to model the tested specimens so that the accurate behavior of the FE-modeled specimens could be examined under test conditions. To achieve desirable results for the modeling of the specimens, in addition to the novel procedure described in this research, the modified versions of models presented by previous researchers were also utilized. After the completion of modeling, the load-axial strain and load-lateral strain relationships, ultimate strength, and failure mode of the modeled CFST specimens were evaluated against the test data, through which the satisfactory accuracy of this modeling procedure was established. Afterward, using a parametric study, the effect of factors such as the concrete core strength at different temperatures and the D/t ratio on the behavior of the CFST columns was explored. Finally, the compressive strength values obtained from the FE model were compared with the corresponding values predicted by various codes, the results of which indicated that most codes were conservative in terms of these predictions.

• Journal of the Korean Society of Propulsion Engineers
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• v.24 no.5
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• pp.21-33
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• 2020

In this study, the program for system analysis of an expander cycle rocket engine using liquid hydrogen as a fuel was developed. The properties of hydrogen were considered by the ratio of isomers with temperature. The analysis procedure was established with the open and closed types of the expander cycle engine and the simulation methods were suggested for each component. To validation of the analysis program, we compared the performance of the engine operating point and the analysis results performed overseas for Vinci and SE-21D, which are expander cycle engines. As a result of the analysis, the main performance factors of the system, such as the mass flow of the propellant, specific thrust, and power, except for some of the inaccurate input information, showed high accuracy with an error of around 1-2%.