• Polymer(Korea)
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• v.30 no.3
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• pp.196-201
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• 2006

Poly (ethylene glycol)-based diblock and triblock thermo- sensitive polyester copolymers were investigated for application on tissue engineering and injectable biomaterials in drug delivery system due to their nontoxicity, biocompatibility and biodegradability. We synthesized the diblock copolymers consisting of methoxy poly (ethylene glycol) (MPEG) (Mn=750 g/mole) and poly $(\varepsilon-caprolactone)$ (PCL) by ring opening polymerization of $\varepsilon-CL$ with MPEG as an initiator in the presence of HCl $Et_2O$. The effect of diblock copolymers on in vivo osteogenic differentiation of rat bone marrow stromal cells (BMSCS) with and without the presence of osteogenic supplements (dexamethasone) was investigated. Thin sections were cut from paraffin embedded tissues and histological sections were stained by H&E, von Kossa, and immunohistochemical staining for osteocalcin. In conclusion, dexamethasone containing thermo- sensitive hydrogel might be improved osteogenic differentiation of BMSCs. We expect the osteoinduction effect to be excellent when it uses stem cell or other osteogenic materials.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.2
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• pp.83-92
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• 2018

Using ground moving target indicators equipped with synthetic aperture radars for locating moving targets within a wide background clutter in a short time is an excellent method for monitoring traffic. Although the displaced phase center antenna (DPCA) technique and along track interferometry (ATI) are real time methods with low computational complexity, they are essential for reducing cases of false alarm that can result in poor performance. In this paper, we propose two detection methods using DPCA and ATI-the parallel fusion method and serial fusion method. Simulation results demonstrate that the proposed detection methods are characterized by low probability of false alarm along with good performance. In particular, the serial fusion method possesses high detection probability along with low probability of false alarm (1/5th of the false alarm probability of the DPCA technique).

• Journal of Ceramic Processing Research
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• v.20 no.1
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• pp.63-68
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• 2019

We investigated the effects of Al2O3 addition on (1-x)Li2B4O7-xAl2O3 (LBAO; x = 0, 0.005, 0.01, 0.05, 0.07, and 0.1) glasses. The glasses were synthesized by a conventional melt-quench method. Structural transformations of the LBAO glasses were assessed via X-ray diffraction analysis. Estimations of ΔT, KGS = (Tc-Tg)/(Tm-Tc), activation energy, and the Avrami parameter were performed using differential thermal analysis and differential scanning calorimetry. An interpretation of non-isothermal kinetics of the crystallization process is presented using the modified Ozawa equation. The activation energy E increased from 3.3 to 3.5 eV for the LBAO (x < 0.01) glasses whereas those of the LBAO (x > 0.05) glasses slightly increased from 3.75 to 4.05 eV. The exponent n was estimated to be 3.9 ± 0.1 for the LBAO (x < 0.01) glasses and 3.2 ± 0.02 for the LBAO (x > 0.05) glasses. Microstructural characterization of the glassy and crystalline phases using atomic force microscopy was investigated. The effects of Al2O3 on the LBAO glasses include a decreased nucleation rate in the crystallization process and a significantly reduced crystal size.

• The Plant Pathology Journal
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• v.18 no.2
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• pp.57-62
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• 2002

In vivo expression technology (IVET) has been developed to study bacterial gene expression in Salmonella typhimurium during host infection. The expression of selected genes by IVET has been elevated in vivo but not in vitro. The selected genes turned out to be important for bacterial virulence and/or pathogenicity. IVET depends on a synthetic operon with a promoterless transcriptional fusion between a selection marker gene and a reporter gene. The IVET approach has been successfully adapted in other bacterial pathogens and plant-associated bacteria using different selection markers. Pseudomonas putida suppresses citrus root rot caused by Phytophthora parasitica and enhances citrus seedling growth. The WET strategy was adapted based on a transcriptional fusion, pyrBC'-lacZ, in P. putida to study the bacterial traits important far biocontrol activities. Several genes appeared to be induced on P. parasitica hyphae and were found to be related with metabolism and regulation of gene expression. It is likely that the biocontrol strain took a metabolic advantage from the plant pathogenic fungus and then suppressed citrus root rot effectively. The result was parallel with those from the adaptation of IVET in P. fluorescens, a plant growth promoting rhizobacteria (PGPR). Interestingly, genes encoding components for type III secretion system have been identified as rhizosphere-induced genes in the PGPR strain. The type III secretion system may play a certain role during interaction with its counterpart plants. Application of IVET has been demonstrated in a wide range of bacteria. It is an important strategy to genetically understand complicated bacterial traits in the environment.

• International journal of advanced smart convergence
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• v.7 no.1
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• pp.1-6
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• 2018

In addition to the instability of energy import costs caused by the depletion of petroleum resources, which is a representative energy resource, and the strengthening of various regulations such as the convention on climate change, the plant for bio energy production, which is being watched as the next generation energy, and became subject of various complaints. In order to solve this problem, the bio-plant is underground and the ground is parked, making the convenience and accessibility of citizens more and more accessible. In this situation, the development of bioenergy production technology also increases the risk factor in bioenergy production process. Accordingly this paper explains method about apply the wide angle camera based AOA algorithm to the bio plant to prevent the accidents from spreading due to the lack of facilities and safety devices and the aging of the facilities and suggests a technique that can quickly identify the location and direction when it occurs.

• Tribology and Lubricants
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• v.27 no.6
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• pp.344-350
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• 2011

Friction and wear behavior of tungsten oxide nanorods (TONs) was investigated using friction force microscopy(FFM) employing colloidal probes instead of conventional sharp tips. Vertically well-ordered TONs with 40 nm diameter, 130 nm length and 100 nm pitch width were synthesized on an anodic aluminium oxide substrate using two step electrochemical anodizing processes. The colloidal probe (diameter 20 ${\mu}m$) attached at the free end of tipless cantilever was oscillated(scanned) against a stationary surface of vertically aligned TONs with various scan speeds (1.2 ${\mu}m/s$, 3.0 ${\mu}m/s$ and 6.0 ${\mu}m/s$) and sliding cycles (100, 200 and 400) under normal load of 800 nN. The friction force and wear depth decreased with the increase of the scan speed. Plastically deformed thin layers were formed and sparsely deposited on the worn nonorod surface. The lower wear rate of the TONs with the longer oscillating cycles was attributed to the decreased real contact pressure due to the increase of real contact area between the colloidal probe and the TONs.

• Current Optics and Photonics
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• v.1 no.1
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• pp.12-16
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• 2017

Color sensor systems based on M13 bacteriophage are being considerably researched. Although many studies on M13 bacteriophage-based chemical sensing of TNT, endocrine disrupting chemicals, and antibiotics have been undertaken, the fundamental physical and chemical properties of M13 bacteriophage-based nanostructures require further research. A simple M13 bacteriophage-based colorimetric sensor was fabricated by a simple pulling technique, and M13 bacteriophage was genetically engineered using a phage display technique to exhibit a negatively charged surface. Arrays of structurally and genetically modified M13 bacteriophage that can determine the polarity indexes of various alcohols were found. In this research, an M13 bacteriophage-based color sensor was used to detect various types of alcohols, including methanol, ethanol, and methanol/butanol mixtures, in order to investigate the polarity-related property of the sensor. Studies of the fundamental chemical sensing properties of M13 bacteriophage-based nanostructures should result in wider applications of M13 bacteriophage-based colorimetric sensors.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.25 no.11
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• pp.595-599
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• 2013

The pipes used in buildings are generally categorized into metallic or plastic materials. Metal pipes, such as copper and stainless steel pipes, are mainly used for water and hot water supply, and for the heating system. However, plastic pipes made of polyethylene and cross-linked polyethylene are used for floor heating, water drainage, and air vent systems. Usually, plastic pipes have thermal demerits, such as high linear expansion coefficients and bending phenomenon by hot water, although the pipes have several merits of light weight, low price, low thermal conductivity, and the comparatively high workability of metal pipes. Therefore, if those kind of demerits are overcome, plastic pipes can be easily accepted for hot water systems. This research is aimed to evaluate the applicability for vertical heating pipes of a plastic pipe system consisting of electric fusion fitting of a conductive carbon compound and propylene random glass fiber pipe, through measurement of the expansion rate and leakage in summer and winter seasons, in the apartment construction field.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.6
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• pp.567-577
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• 2017

Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes. Obesity is associated with impairment of mitochondrial function (e.g., decrease in $O_2$ respiration and increase in oxidative stress) in skeletal muscle. The balance between mitochondrial fusion and fission is critical to maintain mitochondrial homeostasis in skeletal muscle. Obesity impairs mitochondrial dynamics, leading to an unbalance between fusion and fission by favorably shifting fission or reducing fusion proteins. Mitophagy is the catabolic process of damaged or unnecessary mitochondria. Obesity reduces mitochondrial biogenesis in skeletal muscle and increases accumulation of dysfunctional cellular organelles, suggesting that mitophagy does not work properly in obesity. Mitochondrial dysfunction and oxidative stress are reported to trigger apoptosis, and mitochondrial apoptosis is induced by obesity in skeletal muscle. It is well known that exercise is the most effective intervention to protect against obesity. Although the cellular and molecular mechanisms by which exercise protects against obesity-induced mitochondrial dysfunction in skeletal muscle are not clearly elucidated, exercise training attenuates mitochondrial dysfunction, allows mitochondria to maintain the balance between mitochondrial dynamics and mitophagy, and reduces apoptotic signaling in obese skeletal muscle.

• International Journal of Advanced Culture Technology
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• v.5 no.1
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• pp.90-97
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• 2017

Nowadays, the most of commercial buildings are build-out with complex architecture and decorated with more complicated interiors of buildings so establishing intelligible escape routes becomes an important case of fire or other emergency in a limited time. The commercial buildings are already equipped with multiple exit signs and these exit signs may create confusion and leads the people into different directions under emergency. This can jeopardize the emergency situation into a chaotic state, especially in a complex layout buildings. There are many research focused on implementing different approached to improve the exit sign system with better visual navigating effects, such as the use of laser beams, the combination of audio and video cues, etc. However the digital signage system based emergency exit sign management is one of the best solution to guide people under emergency situations to escape. This research paper, propose an intelligent evacuation route GUIDE that uses the combination centralized Wireless Sensor Networks (WSN) and digital signage for people safety and avoids dangers from emergency conditions. This proposed system applies WSN to detect the environment condition in the building and uses an evacuation algorithm to estimate the safe route to escape using the sensor information and then activates the signage system to display the safe evacuation route instruction GUIDE according to the location the signage system is installed. This paper presented the prototype of the proposed signage system and execution time to find the route with future research directions. The proposed system provides a natural intelligent evacuation route interface for self or remote operation in facility management to efficiently GUIDE people to the safe exit under emergency conditions.