• Journal of Engineering Education Research
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• v.17 no.4
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• pp.25-32
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• 2014

Following the collaborator meetings report towards practical engineering education at universities(June 2010), the Pioneering University Reform Project supported by The Ministry of Education, Culture, Sports, Science and Technology(MEXT) of Japan solicited opinions from industry, professional associations, and academia on the goals of the individual fields, as well as common goals, that could be adaptable and applicable for a broad range of universities and curricula. This paper gives an overview of two surveys that were conducted, as well as a summary of the mechanical engineering goals as an example of the individual fields.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8051-8055
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• 2014

Background: A common genetic variant rs3757318, located in intron of C6orf97, was firstly identified to be associated with breast cancer (BC) risk by a genome-wide association (GWA) study. However, subsequent validation studies with different ethnicities have yielded conflicting results. Materials and Methods: We performed a meta-analysis to synthesize all available data for evaluating the precise effect of this variant on BC susceptibility. Results: A total of 8 articles containing 11 studies with 62,891 cases and 65,635 controls were included in this meta-analysis. When compared to the G allele, the rs3757318-A allele was significantly associated with BC risk with the pooled OR of 1.21 (95% CI=1.15 - 1.29, P<0.001) but with obvious between-study heterogeneity (P=0.040). Stratified analysis suggested that diversity of ethnicity along with control source may explain part of the heterogeneity. Similarly, significant associations were also identified in heterozygote, homozygote, dominant and recessive genetic models. Sensitivity and publication bias analyses indicated robust stability of our results. Conclusions: Our present meta-analysis demonstrated that the variant rs3757318 is associated with increased BC risk. Nevertheless, further studies are needed to clarify the underlying biological mechanisms.

• Molecules and Cells
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• v.40 no.2
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• pp.109-116
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• 2017

Soybean agglutinin (SBA) is an anti-nutritional factor of soybean, affecting cell proliferation and inducing cytotoxicity. Integrins are transmembrane receptors, mediating a variety of cell biological processes. This research aims to study the effects of SBA on cell proliferation and cell cycle progression of the intestinal epithelial cell line from piglets (IPEC-J2), to identify the integrin subunits especially expressed in IPEC-J2s, and to analyze the functions of these integrins on IPEC-J2 cell cycle progression and SBA-induced IPEC-J2 cell cycle alteration. The results showed that SBA lowered cell proliferation rate as the cell cycle progression from G0/G1 to S phase (P < 0.05) was inhibited. Moreover, SBA lowered mRNA expression of cell cycle-related gene CDK4, Cyclin E and Cyclin D1 (P < 0.05). We successfully identified integrins ${\alpha}2$, ${\alpha}3$, ${\alpha}6$, ${\beta}1$, and ${\beta}4$ in IPEC-J2s. These five subunits were crucial to maintain normal cell proliferation and cell cycle progression in IPEC-J2s. Restrain of either these five subunits by their inhibitors, lowered cell proliferation rate, and arrested the cells at G0/G1 phase of cell cycle (P < 0.05). Further analysis indicated that integrin ${\alpha}2$, ${\alpha}6$, and ${\beta}1$ were involved in the blocking of G0/G1 phase induced by SBA. In conclusion, these results suggested that SBA lowered the IPEC-J2 cell proliferation rate through the perturbation of cell cycle progression. Furthermore, integrins were important for IPEC-J2 cell cycle progression, and they were involved in the process of SBA-induced cell cycle progression alteration, which provide a basis for further revealing SBA anti-proliferation and anti-nutritional mechanism.

• Mass Spectrometry Letters
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• v.6 no.1
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• pp.13-16
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• 2015

This study demonstrated the stabilizing role of a cyclodextrin on Keggin $[PW_{12}O_{40}]^{3-}$ via hydrogen bonding complexation unveiled by ESI-MS. The distinctive fragmentation pathways of the $\{PW_{12}\}/{\gamma}$-CD complexes from that of discrete $[PW_{12}O_{40}]^{3-}$ showed that the so-called "weak" non-covalent interactions can effectively change the dissociation chemistry of POM in the gas phase. The influence of different types of solvents and organic additives such as ${\gamma}$-CD on the stability of Keggin $[PW_{12}O_{40}]^{3-}$ was also addressed firstly by ESI-MS.

• International Journal of Computer Science & Network Security
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• v.21 no.5
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• pp.16-22
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• 2021

• International Journal of Computer Science & Network Security
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• v.21 no.11
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• pp.363-367
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• 2021

This article analyzes the state and development of multimedia technologies in the educational process. The reasons for the emergence of multimedia educational technologies are shown. The definition of the concept of "multimedia education" is given. The advantages and disadvantages of teaching using multimedia technologies are presented. The article, based on multimedia technologies, provides one of the ways to solve the problem of lack of classroom time for the presentation of all educational material in the process of teaching engineering students. The creation and application of educational videos in education is discussed, an example of teaching electrical engineering is given; the requirements for the development of video lessons, their advantages and importance in the educational process are indicated.

• International Journal of Advanced Culture Technology
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• v.11 no.1
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• pp.135-146
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• 2023

Psychological support is crucial in navigating one's academic and professional lives, especially for students living abroad and pursuing higher education. This study aims to explore the narratives of social support seeking in a group of Korean international graduate students in an urban university setting in the United States. Qualitative research method of narrative approach was used to examine how three Korean graduate students exchanged psychological support. Analysis of interviews, observations, and documents found that four types of social support (informational, instrumental, appraisal, and emotional) were being exchanged and that emotional support was accessible predominantly in individual meetings than in group gatherings. Additionally, the reasons for abstaining from initiating group gatherings are discussed in relation to the Korean culture where participants were mindful of not infringing on each other's time. These findings inform theory on socio psychological support seeking and its relation to cultural values and offer practical insights into psychological support in international students in higher education settings.

• International Journal of Advanced Culture Technology
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• v.11 no.1
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• pp.18-26
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• 2023

The use of holographic standardized patient (HSP) with mixed reality can provide students with the opportunity to enhance clinical reasoning skills. This is still relatively new, so there is a lack of guidelines for educators. Thus, we aimed to develop the instructional model of HSP-based education, for enhancing clinical reasoning skills in undergraduate healthcare education, which could systematically guide educators in designing and implementing HSP-based teaching and learning activities appropriately. Using a design and development research, a theoretically constructed initial mode in this study was iteratively improved and underwent validation through expert review and model usability test. Features of the model were discussed, along with theoretical and practical implications and suggestions for further research.

• Educational Technology International
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• v.18 no.2
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• pp.249-263
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• 2017

The purpose of this study was to examine whether respondents showed gender differences in life- learning competency, self-directed learning ability, problem-solving ability, and academic achievement and to identify relationships among variables of university students in the context of higher education. To address those goal, the data set was analyzed that nationally collected from Korea Youth Competency Measurement and International Comparative Research III by National Youth Policy Institute in South Korea. 680 samples were used in the study that were 343 males and 337 females of university students. As results, statistically significant difference was showed in the participants' gender. Male university students were higher score than female university students in All variables. Also, learning agility in life-learning competency was strongly related to self-directed learning ability and problem-solving. Thinking skills in life-learning competency was strongly related to academic achievement in university students in higher education. In terms of learning strategy in the context of higher education, some suggestions have been made for university students.

• International Journal of Advanced Culture Technology
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• v.12 no.2
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• pp.119-135
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• 2024

The research is centered on veteran educators in the field of early childhood education who possess more than 20 years of teaching experience and have been recognized with awards for their outstanding achievements. The selection of participants was based on specific criteria, such as the number of years of experience and recognition received from the Ministry of Education's Teaching Innovation Competition in Korea. Eight teachers who met the specified criteria were selected to participate in the study. A qualitative phenomenological research study was carried out using semi-structured interviews to gain insight into the experiences and perspectives of the participants. The study identified five main themes: cultivating interpersonal relationships, establishing interactive classroom settings, providing impactful educational methodologies, facilitating healthy habits and character education, and creating a supportive environment for teachers' well-being. The study seeks to improve comprehension of teaching methodologies and offer suggestions for professional development, teacher training, and educational policies.