• Journal of Microbiology and Biotechnology
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• v.34 no.4
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• pp.838-845
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• 2024

Excessive alcohol consumption can have serious negative consequences on health, including addiction, liver damage, and other long-term effects. The causes of hangovers include dehydration, alcohol and alcohol metabolite toxicity, and nutrient deficiency due to absorption disorders. Additionally, alcohol consumption can slow reaction times, making it more difficult to rapidly respond to situations that require quick thinking. Exposure to a large amount of ethanol can also negatively affect a person's righting reflex and balance. In this study, we evaluated the potential of lactic acid bacteria (LAB) to alleviate alcohol-induced effects and behavioral responses. Two LAB strains isolated from kimchi, Levilactobacillus brevis WiKim0168 and Leuconostoc mesenteroides WiKim0172, were selected for their ethanol tolerance and potential to alleviate hangover symptoms. Enzyme activity assays for alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) were then conducted to evaluate the role of these bacteria in alcohol metabolism. Through in vitro and in vivo studies, these strains were assessed for their ability to reduce blood alcohol concentrations and protect against alcohol-induced liver damage. The results indicated that these LAB strains possess significant ethanol tolerance and elevate ADH and ALDH activities. LAB administration remarkably reduced blood alcohol levels in rats after excessive alcohol consumption. Moreover, the LAB strains showed hepatoprotective effects and enhanced behavioral outcomes, highlighting their potential as probiotics for counteracting the adverse effects of alcohol consumption. These findings support the development of functional foods incorporating LAB strains that can mediate behavioral improvements following alcohol intake.

• Journal of Technology Innovation
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• v.31 no.2
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• pp.135-172
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• 2023

When discussing a company's technology management, manufacturing companies' innovation strategy is vital because it is connected to each company's competitive advantage in various ways, such as technology acquisition, R&D, and product innovation. The research on manufacturing companies' innovation strategies has been studied in various ways, such as performance and resources for innovation; however, very little research has been done to synthesize existing research outcomes. In this study, we conduct a systematic literature review of 51 articles related to manufacturing companies' innovation strategies. By doing so, we synthesized the results of extant studies based on three perspectives: the research target, the research focus, and the types of innovation strategies. In addition, I derived the unique properties of the research on manufacturing companies' innovation strategies. The analysis indicated that Korea's research on manufacturing companies' innovation strategies had been unequally distributed. Based on this, we suggested research agendas for future research on manufacturing companies' innovation strategies.

• Journal of Technology Innovation
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• v.13 no.2
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• pp.157-178
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• 2005

During the transformation of the agro-technology extension in rural China, many new Policy experiments are emerging to rebuild the lost linkages and to improve technology transfer with the system and among systems. Applying the Triple Helix Model of academy-agriculture-government relations, this paper explores a new pattern of technology transfer with the case of BaojiCity. The authors interpret the mechanism of 'Courtyards for Agro-experts', as well as the comparison between different types of courtyards. This article concludes that the Triple Helix in the agro-sector improves technology transfer and accelerates knowledge-based regional development. In the interest of farmers there should also be concern over reducing inequity the reform.

• STI Policy Review
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• v.6 no.1
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• pp.70-84
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• 2015

The paper discusses technology platforms as an instrument of science, technology and innovation policy in light of their use in industrial R&D. The authors assert that the technology platforms approach as a policy concept refects special organizational and institutional features learned from industrial technology platforms. The characteristics of industrial technology platforms are reviewed, and their impact on the organization of research, development and innovation activities in companies is explored. Second, the industrial technology platform is examined in the context of European Technology Platforms and the recent initiative for technology platforms in Russia. Finally, the technology platform concept implications for the STI policy context are discussed.

• Asian Journal of Innovation and Policy
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• v.9 no.3
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• pp.281-307
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• 2020

A variety of approaches are being applied to improve the existing ex-ante evaluation by expert panels in publicly funded R&D. While the objective evaluation criteria are constantly being improved to screen and select the superior projects, alternative approaches such as random prioritization and logical modeling are also underway to overcome the conservative bias of reviewers and to secure disruptive innovation. This study intends to find critical implications for ex-ante evaluation of public R&D system from the comparison of Indonesia and Korea. For the comparative analysis, literature review and expert in-depth interviews are conducted on the national R&D system and the selection evaluation process. In Korea, the selection criteria of projects are legally promulgated for establishing an objective evaluation system, and at the program level, the major considerations in the planning process are specified by Presidential Decree. On the other hand, while Indonesia conducts R&D in 47 strategic fields largely by public research institutes (PRI) based on the non-competitive government contributions. This study draws out implications of institutionalizing the planning process at the level of program, and of increasing the ratio of contract-based competitive funding at the level of project in the national R&D portfolio.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.4
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• pp.909-916
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• 2021

The purpose of the research to analyze SMEs' technological innovation performance in the Special Region of Yogyakarta based on green supply chains. This study's technology innovation performance is influenced by environmental management practices, green supply chain integration, and supply chain knowledge-sharing. This research is important because many SMEs are underdeveloped in terms of technology innovation performance. Technology innovation performance shows that innovation has a multi-dimensional ecological performance in organizations. Therefore, SMEs' sustainable supply chain could be achieved by managing operations, support, and information by focusing on environmental and social issues to maximize the entire chain. This study used primary data. The number of respondents in this study was 200 SMEs that have implemented green supply chain management practices. The data collection method used was a questionnaire. The data analysis technique tool used is a two-step approach to SEM-AMOS. The results of this study indicate that SMEs are willing to implement a green supply chain to increase their performance. The technological innovation performance model of this study is acceptable. The findings of this research suggest that companies must be encouraged to maintain and increase the implementation of green supply chain integration and better supply chain knowledge-sharing with improved technological innovation performance enhancements.

• STI Policy Review
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• v.6 no.2
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• pp.87-104
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• 2015

Public procurement for innovation is used as one of the major policy tools to stimulate innovation and promote growth of small and medium-sized enterprises (SMEs) in Korea. However, it is evaluated that this policy has not been so effective in promoting technological innovation among SMEs largely because it heavily depends on price competitiveness of SMEs products and services. In order to draw some policy implications, this study examines the PPI policies of selected countries as comparative references and conducts an empirical analysis on Korean Public Procurement Services (PPS) data for identifying challenges of the current policy in Korea. We conclude that in order to enhance technological innovations of SMEs, PPI policy in Korea should 1) focus more on the potential competitiveness of SMEs, 2) enlarge public demands especially on R&D services, 3) encourage private sector participation in the public procurement market, 4) improve the assessment criteria for public procurement market registration, and 5) restructure the responsible organizations.

• Asia Pacific Journal of Business Review
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• v.6 no.2
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• pp.1-26
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• 2022

This study uses the human resource management (HRM) practice and ability, motivation, and opportunities (AMO) theory and corporate social and environmental responsibility, to explore the effects of environmental responsible human resource management practice (ER-HRM) on energy-intensive manufacturing's green technology innovation and organizational effectiveness. A self-completed questionnaire was administered to managers of energy-intensive manufacturing in the Lao PDR. The data was collected from 198 managers of energy-intensive manufacturing for analysis. We used structural equation modeling (SEM) by smart PLS 3.0 to test the hypotheses in this research. The findings have shown a strong direct and positive impact of the environmental ability, motivation, and opportunity of ER-HRM practice on green technology innovation and organizational effectiveness. The ability of ER-HRM practice has the highest influence on green technology innovation and organizational effectiveness. The findings also prove the partial mediation of green technology innovation links ER-HRM with organizational effectiveness. This research is expected to identify the influences of ER-HRM in energy-intensive manufacturing to achieve innovation and performance while reducing emissions.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2004.11a
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• pp.498-511
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• 2004

• Journal of Korea Technology Innovation Society
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• v.6 no.3
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• pp.345-357
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• 2003

As the sustaindble development becomes the main goal of the global world in the 21st century, it is important that technological innovations should be realized ecologically sound based on co-evolutionalry approach. From this perspective, the trans-disciplinary research method is gaining importance in the evaluation process of public funded R&D, especially in the environmental technology. In our evaluation research on the R&D projects of the $CO_2$reduction and sequestration technology in Korea, we attempt to apply a trans-disciplinary integrated method on the concept of the eco-innovation, the technology push and the market pull. Also, we try to develop the trans-disciplinary indicators of the environmental technology evaluation. This research confirms the necessity of trans-disciplinary research among the three academic perspectives, engineering, social sciences and public policy.