• Journal of Ginseng Research
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• v.39 no.3
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• pp.230-237
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• 2015

Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered $Apc^{Min/+}$ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10-20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-$1{\alpha}$ (IL-$1{\alpha}$), IL-$1{\beta}$, IL-6, tumor necrosis factor-${\alpha}$, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

• Korean Journal of Agricultural Science
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• v.30 no.1
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• pp.76-88
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• 2003

This study exploits the robot system which is necessary in gene study, bio-technology industry. As well, it can achieve the job of DNA chip manufacturing whose use rate has been increased recently. The robot consists of DNA spotting device for spotting DNA on the silylated slide and well plate, bed for fixing well-plate, washing & drying device of washing and drying the pin part of DNA spotting device, distillation-water vessel, and discharge vessel of wash water. We made the term of sticking DNA to the pin on well plate to be 15 seconds. The spot size of DNA was set to be 0.28 mm on the average by bringing the slide into contact with pin for 1 second. At this rate, if DNA is spotted in the minimum space possible of about 0.32mm, it can stick about 8,100 DNA spots on the well plate. Analyzing the procedure: Movement starts. Pin washes, dries, and smears DNA on the well plate. Spots DNA onto 12 chips takes 2 minutes and 50 seconds.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.12
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• pp.2511-2519
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• 2015

In maritime logistics, the technology for transmitting status information has been greatly developed, but it has not been available in general logistics environment or it is impossible to support two-way communication as it simply receives and transfers a container's information. In particular, to support two-way communication in all sections of the global maritime logistics, the address value, which can identify the tag, should be managed. In this context, to improve the 433 MHz-based RFID, the project called "DASH 7" has been conducted in recent years. However, it has stopped proceeding because of its slow progress, including the standardization and development of references. In this paper, we introduced an active IP-RFID system configuration for real-time communication in global maritime logistics using a two-way communication-which is characteristic of an IP-applying virtual address values in the RFID tag, and proposing its process and function. When you apply the IP-RFID system proposed in this paper, not only real-time status tracking in the maritime logistics area is possible, but it is also applicable for controlling the tag.

• The Journal of Engineering Geology
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• v.19 no.3
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• pp.389-400
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• 2009

Iron and manganese contents are usually over the limit of drinking water standard (0.3 mg/L) in unconsolidated aquifer of river bank filtration site in Nakdong river. Surge block and air surging techniques used in this study are useful tools to remove the slime within gravels and pebbles, to increase permeability of aquifer, to provide oxygen into aquifer, and to discharge iron and manganese oxides from a well. Surging activity brought about $5{\sim}8$ and $5{\sim}9$ times decreases in $Fe_{(total)}$ and $Fe^{2+}$ contents, and also 10 times decrease in $Mn^{2+}$ contents compared to non-surging condition, respectively. Additionally, iron oxide and manganese oxide increased up $1{\sim}1.2$ times after surging. This result shows that air injection into the aquifer can help iron and manganese content decreased and in-situ treatment technology needs to be introduced in river bank filtration project in South Korea.

• Journal of the Korean earth science society
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• v.25 no.7
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• pp.576-585
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• 2004

This study was conducted to analyze the relationships between terms, learning concepts and inquiries in ocean unit, the National Common Basic Curriculum. The several science textbooks were selected to use for study, written in accordance with the 7 current national curriculum for the fourth grade of elementary school, the seventh of middle school and the tenth of high school. The higher the school level becomes, the frequencies of using terms related with ocean region get. The explanation of terms, however, has a tendency to be less frequent in the high school level. In the perspective of learning concept, there are more concrete concepts than formal concepts regardless of school level. Pure scientific context appears most often in inquiry contest through the whole course of every school level. In respect to inquiry process, the frequency of integrative inquiry process is on the increase as the school level gets higher. From the viewpoint of inquiry activity, there have been a lot of discussions, experiments and investigations in every school level, while high school does not the present any field study and project. Through these result, it is considered that the explanation of main terms is inevitable in the textbooks as basic educational material without regard to school level. In learning concept and inquiry context, a well-rounded learning is needed in relation to students' cognitive development and science-technology-society. Especially for the inquiry activity of earth science education, the educational effect is remarkable through field study; its appropriate application is required, accordingly.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.10
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• pp.3911-3916
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• 2010

In this paper we describe contents and results on running test for ATP on-board equipment, which has propelled as one of the research projects, so called, "Reliability assessment and operation technology development for Korean-type tilting trains" in order to ensure the safety and operation efficiency of tilting trains. We developed tilting trains for the speed-up of conventional lines and for the passenger service improvement where the KTX is not available. And we made progress the operation trial test in the 120,000 km distance with the use of ATS equipment, used in existing lines, for the purpose of the reliability assessment of the developed tilting trains. We decided to accelerate the speed for more than 200km/h with respect to the 6 existing lines including Jungang-line and Chungbuk-line where KTX has not operated. According to this decision, Train control system is to be changed from ATS to ATP. We should have installed an ATP on-board unit in tilting trains and verified the operational suitability, therefore we installed the same ATP on-board unit on tilting trains as that used in the ATP construction project on Gyeongbu-line and Honam-line, and verified that the function and performance of the installed ATP on-board unit conformed to the tilting trains operation.

• Nutrition Research and Practice
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• v.10 no.5
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• pp.555-562
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• 2016

BACKGROUND/OBJECTIVES: Childhood obesity has become a global epidemic. Development of effective and sustainable programs to promote healthy behaviors from a young age is important. This study developed and tested an intervention program designed to promote healthy eating and physical activity among young children in South Korea by adaptation of the US National Aeronautics and Space Administration (NASA) Mission X (MX) Program. SUBJECTS/METHODS: The intervention program consisted of 4 weeks of fitness and 2 weeks of nutrition education. A sample of 104 subjects completed pre- and post- surveys on the Children's Nutrition Acknowledgement Test (NAT). Parents were asked for their children's characteristics and two 24-hour dietary records, the Nutrition Quotient (NQ) at baseline and a 6-week follow-up. Child weight status was assessed using Korean body mass index (BMI) percentiles. RESULTS: At baseline, 16.4% (boy: 15.4%; girl: 19.2%) of subjects were overweight or obese (based on $BMI{\geq}85%tile$). Fat consumption significantly decreased in normal BMI children ($48.6{\pm}16.8g$ at baseline to $41.9{\pm}18.1g$ after intervention, P < 0.05); total NQ score significantly increased from 66.4 to 67.9 (P < 0.05); total NAT score significantly improved in normal BMI children (74.3 at baseline to 81.9 after the program), children being underweight (from 71.0 to 77.0), and overweight children (77.1 at baseline vs. 88.2 after intervention, P < 0.001). CONCLUSIONS: The 6-week South Korean NASA MX project is feasible and shows favorable changes in eating behaviors and nutritional knowledge among young children.

• The KIPS Transactions:PartD
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• v.8D no.2
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• pp.154-165
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• 2001

A number of attempts to develop methods for measuring software effort have been focused on the area of software engineering and many models have also been suggested to estimate the effort of software projects. Almost all current models use algorithmic or statistical mechanisms, but the existing algorithmic effort estimation models have failed to produce accurate estimates. Furthermore, they are unable to reflect the rapidly changing technical environment of software development such as module reuse, 4GL, CASE tool, etc. In addition, these models do not consider the paradigm shift of software engineering and information systems(i.e., Object Oriented system, Client-Server architecture, Internet/Intranet based system etc.). Thus, a new approach to software effort estimation is needed. After reviewing and analyzing the problems of the current estimation models, we have developed a model and a system architecture that will improve estimation performance. In this paper, we have adopted a neural network model to overcome some drawbacks and to increase estimation performance. We will also address the efficient system architecture and estimation procedure by a similar case-based approach and finally suggest the heuristic search method to find the best estimate of target project through empirical experiments. According to our experiment with the optimally parsimonious neural network model the mean error rate was significantly reduced to 14.3%.

• Ocean and Polar Research
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• v.30 no.4
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• pp.379-399
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• 2008

Spatial-temporal variations in physiochemical water qualities (temperature, salinity, DO, SPM, POC and nutrients) of surface and bottom waters were investigated along the mid-western coastal area (Taean Peninsula to Gomso Bay) of Korea. Spatial distribution patterns of temperature and salinity were mostly controlled by the physical mixing process of freshwater from Geum River and/or Gyunggi Bay with nearby coastal water. A strong tidal front is formed off Taean Peninsula during spring and summer. Seasonal variations in nutrient concentrations, lower in spring and summer and higher in fall and winter, are primarily regulated by magnitude of phytoplankton occurrence rather than freshwater loadings into the bay. Based on seasonal and spatial variability of physicochemical parameters, water quality of the study area can be divided into four water masses; Gyunggi Bay-influenced Water Mass (GBWM), Geum River-influenced Water Mass (GRWM), Yellow Sea Bottom Cold Water Mass (YSBCWM) and Cheonsu Bay Water Mass (CBWM). Water quality of the GBWM (Taean Peninsula coastal area), which has relatively low salinity and high concentrations of nutrients, is strongly controlled by the Gyunggi Bay coastal water, which is under influence of the Han River freshwater. In this water mass, the mixed layer is always developed by strong tidal mixing. As a result, a tidal front is formed along the offshore boundary of the mixed layer. Such tidal fronts probably play an important role in the distribution of phytoplankton communities, SPM and nutrients. The GRWM, with low salinity and high nutrients, especially during the flood summer season, is closely related to physiochemical properties of the Geum River. During the flood season, nutrient-enriched Geum River water mass extends up to 60 km away from the river mouth, potentially causing serious environmental problems such as eutrophication and unusual and/or noxious algal blooms. Offshore (<$30{\sim}40m$ in water depth) of the study area, YSBCWM coupled with a strong thermocline can be identified in spring-summer periods, exhibiting abundant nutrients in association with low temperature and limited biological activity. During spring and summer, a tidal front is formed in a transition zone between the coastal water mass and bottom cold water mass in the Yellow Sea, resulting in intensified upwelling and thereby supplying abundant nutrients to the GBWM and GRWM. Such cold bottom water mass and tidal front formation seems to play an important role in controlling water quality and further regulating physical ecosystem processes along mid-western Korean coastal area.

• Journal of Korean Society of Transportation
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• v.19 no.5
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• pp.21-33
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• 2001

Intelligent Transport Systems (ITS) was first introduced in Korea early 1990's, and Korean government has put a lot of efforts for flourishing it in the entire nation. Regardless of these efforts, private participation is not active enough to accelerate ITS implementation in Korea. Expert group made every endeavor to analyze the current situation, and found out some phenomena. It may be summarized as two folds. Firstly, private sector has a lack of confidence on the future ITS market. Budget in the strategic plan is the only publication and guide that private sector can refer to, and it merely indicates deployment costs. Secondly, direction and procedure of R&D are not well defined. It implies that private sector takes too much risk when they invest for R&D. This research, therefore, focuses on the first issues. Concretely, the goal of the project was to establish and analyze the model for estimation the future ITS market side. Author reviewed both quantitative and qualitative models, and concluded that diffusion model in qualitative model was suitable for ITS market estimation. According to model calibration. it is estimated that 14 trillion Won was the market size in 2020 under normal condition. Impact of this result may seduce Information Technology(IT) related private companies into ITS market. Although this research couldn't cover various topics, it nay dedicate in boosting ITS in Korea. Also, it will be a good starting point for further study for the advancement of ITS.