• Proceedings of the KSME Conference
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• 2001.06c
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• pp.128-133
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• 2001

For the Z-level machining, a tool-path linking procedure is presented. The linking problem is approached from the technological requirements, such as considering the machining constraints among the tool-path-elements, minimizing the tool-path length and reflecting the oneway/zigzag linking option. To simplify the linking problem, we develop a data structure, called a TPE-net, providing information on the machining constraints among the tool-path-elements. By making use of the TPE-net, the tool-path linking problem becomes a touring problem so that every node has been traversed.

• Korean Journal of Computational Design and Engineering
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• v.16 no.4
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• pp.300-304
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• 2011

This paper proposes an approach to generate tool-path for laser pattern machining. Considering the mechanical structure of a laser pattern machine, it is quite similar to that of a 2D milling machine. Based on the observation, one may try to utilize the tool-path generation methodologies of 2D milling for the laser pattern machining. However, it is not possible to generate tool-path without considering the technological requirements of laser pattern machining which are different from those of 2D milling. In this paper, we identify the technological requirement of laser pattern machining, and propose a proper tool-path generation methodology to satisfy the technological requirements. For the efficient generation of tool-path, this paper proposes a tool-path element computation method, which is based on the concept of a monotone chain.

• Korean Journal of Clinical Laboratory Science
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• v.50 no.2
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• pp.77-84
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• 2018

In Singapore, biosafety and biosecurity measures are controlled by the Biological Agents and Toxins Act (BATA) and other requirements by regulatory agencies. The law prohibits and otherwise regulates the possession, use, import, transhipment, transfer, and transportation of biological agents, inactivated biological agents, and toxins that are of public health concern. The law also defines the facility requirements for high risk biological agents and toxins. The containment facility (BSL 3) is a minimum requirement to handle biological agents that falls under Schedule 1 (Risk Group 3). The Nanyang Technological University School of Biological Sciences Biosafety Level 3 Facility (NTU-SBS BSL 3) was designed specifically for research involving potential hazardous biological materials. The facility requires yearly re-certification by an approved facility certifier to meet the local requirements and international biosafety standards for a containment facility in many instances. On the other hand, most NTU researchers conduct biological projects involving biological agents with low or moderate risk groups (Risk Groups 1 and 2 or biological agents described in schedule 3 and 4 of BATA) and GMOs, which need only a BSL 2 laboratory. BSL 2 laboratories are yet to be legally certified or registered in Singapore. Institutional Biosafety Committee (IBC) identifies the requirements; defines a minimum standard in the safe control of biological risks and registers all BSL 2 laboratories in the NTU. Therefore, under the guidance of the IBC, the University Biosafety and Biosecurity Programme includes the audit and certification program as a unique and an internal exercise to bring NTU biosafety to a higher level.

• Structural Engineering and Mechanics
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• v.10 no.2
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• pp.93-110
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• 2000

An alternative interpretation of the completeness requirements for the higher order elements is presented. Apart from the familiar condition, $\sum_iN_i=1$, some additional conditions to be satisfied by the shape functions of higher order elements are identified. Elements with their geometry in the natural form, i.e., without any geometrical distortion, satisfy most of these additional conditions inherently. However, the geometrically distorted elements satisfy only fewer conditions. The practical implications of the satisfaction or non-satisfaction of these additional conditions are investigated with respect to a 3-node bar element, and 8- and 9-node quadrilateral elements. The results suggest that non-satisfaction of these additional conditions results in poorer performance of the element when the element is geometrically distorted. Based on the new interpretation of completeness requirements, a 3-node element and an 8-node rectangular element that are insensitive to mid-node distortion under a quadratic displacement field have been developed.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.02a
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• pp.19-25
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• 2002

Profile machining using cutter diameter compensation is widely used in die and mould manufacturing. Especially automotive die makers try to use 3D-profile machining for trimming or flange dies. But the technological requirements and implementation issues haven't been defined. In this paper we summarized the requirements and issues of 3D-profile machining. Approximation of input profiles into sequences of line and helical arc is the first major issue. The second major issue is removing cutter interference from the approximated curves holding z-values when the maximum cutter diameter is given. Keeping constant machining width, local machining, path linking problems and several detail technological requirements are also discussed.

• Korean Journal of Computational Design and Engineering
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• v.7 no.3
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• pp.141-147
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• 2002

Profile machining using cutter diameter compensation is widely used in die and mould manufacturing. Especially automotive die makers try to use 3D-profile machining for trimming or flange dies. But the technological requirements and implementation issues haven't been defined. In this paper we summarized the requirements and issues of 3D-profile machining. Approximation of input profiles into sequences of line and helical arc is the first major issue. The second major issue is removing cutter inter- ference from the approximated curves holding z-values when the maximum cutter diameter is given. Keeping constant machining width, local machining, path linking problems and several detail technological requirements are also discussed.

• International Journal of Stem Cells
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• v.17 no.2
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• pp.130-140
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• 2024

Cardiac organoids have emerged as invaluable tools for assessing the impact of diverse substances on heart function. This report introduces guidelines for general requirements for manufacturing cardiac organoids and conducting cardiac organoid-based assays, encompassing protocols, analytical methodologies, and ethical considerations. In the quest to employ recently developed three-dimensional cardiac organoid models as substitutes for animal testing, it becomes imperative to establish robust criteria for evaluating organoid quality and conducting toxicity assessments. This guideline addresses this need, catering to regulatory requirements, and describes common standards for organoid quality and toxicity assessment methodologies, commensurate with current technological capabilities. While acknowledging the dynamic nature of technological progress and the potential for future comparative studies, this guideline serves as a foundational framework. It offers a comprehensive approach to standardized cardiac organoid testing, ensuring scientific rigor, reproducibility, and ethical integrity in investigations of cardiotoxicity, particularly through the utilization of human pluripotent stem cell-derived cardiac organoids.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.16 no.2
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• pp.23-40
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• 2013

The natural environment restoration industry has been newly included in the environment area of engineering technology. Accordingly, the enactment of a standard of estimate for determining the 'Cost plus Fixed Fee' method has become necessary for the implementation and vitalization of natural environment restoration projects. The purpose of this study is to determine the standards for which the prices for engineering projects are calculated with respect to the enactment of an engineering project standard of estimate in the natural environment restoration field. These include the scope of the technological work, standard area, manpower requirements by technical grade that are necessary for carrying out the technological tasks. Relevant laws and regulations, systems and precedent case studies were investigated and analyzed to establish a price calculation standard. The overall results of the analysis were used and applied to questionnaires, public hearings, and expert delphi techniques. The study showed the following results： The scope of the technological work was categorized into 'Biotopes', 'Eco-corridors' and 'Ecological restoration'. The standard area was set up as $1,000m^2$ for 'Biotopes' and $5,000m^2$ for 'Eco-corridors' and 'Ecological restoration'. The manpower requirements by technical grade that are necessary for carrying out the technological tasks were determined. The suitability of the costs, standard area, manpower requirements by technical grade of ordered engineering projects that are determined by applying the standard of estimate for natural environment restoration that may be enacted pursuant to this study may be effectively investigated and analyzed. Moreover, further studies on the calculation of standard prices that can ensure the stability of natural environment restoration projects will be necessary.

• Journal of Satellite, Information and Communications
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• v.7 no.1
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• pp.116-121
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• 2012

For the purpose of drawing out the technological criteria for the development of an Low Earth Orbit Meteorological Satellite some characteristics of infrared and microwave sensors on the payload were analysed by approaching theoretically. In addition, the channel requirements and interface requirements of the microwave sensors equipped on the payloads of the existing foreign Low Earth Orbit Meteorological Satellites were analysed with respect to the development of an Earth Orbit Meteorological Satellite payload. In this paper, the multipurpose satellite bus and the CAS 500 platform as the interface requirements of an Low Earth Orbit Meteorological Satellite, and core subsystem and principle functional requirements of a satellite control system were systematically described.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.35
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• pp.95-106
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• 1995

This study is aimed at development a plan to strengthen the competitiveness in technology of small and medium manufacturing enterprises, which can be assumed mainly by small and medium manufacturing companies, to improve the competitiveness of domestic industry. To remove these obstacles and strengthen the technological competitiveness, internally it is required to change the attitude of management about the development and innovation of technology first. Promotion of favorable atmosphere for the technological development and organized activity to acquire technological information are additional requirements. In conclusion, to survive the competition and to secure national industrial competitiveness, each individual company needs to endeavor for technological innovation and improvement in product quality and productivity.