• 품질경영학회지
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• 제46권3호
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• pp.551-568
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• 2018

Purpose: This study addressed the relationship between technological innovation activity and management efficiency of Korean automobile firms. We tested the hypothesis of non-liner relationship of innovation activity in relation to management efficiency. Methods: We discussed prior literature in the firm innovation strategy and management efficiency studies to provide better understanding of relationships between technological innovation activity and management efficiency. As a result, we developed develop and tested a model (Inverted-U shaped) capturing the non-linear impact of technological innovation activity. While we used R&D expenditure and patent registration data for measuring firms' innovation activity, management efficiency was evaluated by using DEA(Data Envelopment Analysis). Results: Main findings of our empirical analysis indicated that the relationships between technological innovation activity and management efficiency was inverted U shaped. This implied that the relationship between technological innovation and management efficiency is inverted U-shaped non-linear, with management efficiency increasing up to a point, beyond which higher levels of R&D and patent registration activities led to a decrease in management efficiency. Conclusion: This study empirically assessed the inconclusive findings of previous research in the area of effects of innovation activities in relation to firm performance. The paper also provided theoretical and practical implications for firms who explore efficient strategy to promote the management performance through technological innovation activities. Future research directions with the limitation of the study was discussed.

• 정보학연구
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• 제2권1호
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• pp.163-175
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• 1999

기술혁신은 모든 산업에 있어 차별적 경쟁우위의 주요한 원천이 되면서 동시에 기업의 많은 자원이 투자되는 경영활동이라고 할 수 있다. 따라서 많은 성공적인 기업의 이면에는 반드시 뛰어난 기술혁신과 이를 위한 투자가 있다. 그러나 기술혁신투자가 모든 경우에 바람직한 성과로 직결되는 것은 아니며 생산전략 및 생산활동과 효과적으로 연계되어야만 가능할 것이다. 본 연구는 Abernathy St Utterback(1975)의 기술혁신모형을 국내 전자산업을 대상으로 실증적으로 검증하고 기술혁신이 생산전략 및 생산활동과 어떠한 상관관계를 가지고 있는지를 분석하였다. 따라서 이러한 연구결과를 바탕으로 기술혁신이 기업성과에 미치는 영향에 관한 규범적 연구의 토대를 구축하는 것이 본 연구의 궁극적 목표이다.

• 디지털융복합연구
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• 제12권5호
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• pp.115-123
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• 2014

차세대 이동통신 관련 경쟁기업의 기술적 역량분석을 위해 특허정보 분석을 실시하였다. 특허정보의 분석방법으로는 출원인 분석, 기술분류 분석, 지표분석 등 여러 분석방법을 활용하였다. 경쟁기업의 기술적 역량분석 1단계로 특허활동도(Patent Activity:PA)가 높은 출원인을 선별하였고, 2단계로 기술자립도(Technological Independence:TI)가 높은 기술분류를 선별하였다. 그리고 1단계와 2단계 결과를 매칭하여 특허활동도가 높은 주요 출원인 중에서 기술자립도가 높은 기술분류에 대한 포트폴리오를 작성하였다. 이와 같은 과정을 통해 경쟁기업간에 집중적으로 연구되고 있는 중요 기술 포트폴리오를 분석할 수 있다. 이 분석 결과는 기업의 R&D계획, 특허전략 수립 등 전략적 R&D 관리 수행을 돕는 역할을 할 것이다.

• 한국과학교육학회지
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• 제24권1호
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• pp.76-89
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• 2004

Recent studies of science and technology "in-the-making" revealed that the process of designing material artifacts is not a straightforward application of prior images or theories by one (or more) person(s) isolated from his or her (their) environment. Rather, designing is a process contingent on the social and material setting for both engineering designers and students. Over the past decade, designing technological artifacts has emerged as an important learning environment in science classrooms. Through the analyses of a large database concerning an innovative simple machines curriculum for sixth-and seventh-grade students, we accumulated valid evidence for the nature of the designing process and science learning through it. In this paper, we show that design actions intertwine with the transformation of the objectified raw materials and artifact, the designer collective, and the mediating tools enabling that transformation, which constitute the elements of an activity from the perspective of cultural-historical activity theory. We conceptualize the continuous change of relation between material artifacts, designers, and tools throughout the design activity as co-evolution. Two episodes were selected to exemplify synchronic and diachronic change of relations inherent in co-evolving activity system. Finally, we discuss the implications of co-evolution during design activity for science learning.

• BMB Reports
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• 제38권3호
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• pp.290-293
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• 2005

In order to investigate the epitope of basic fibroblast growth factor (bFGF) and its immunogenicity, the epitopes of bFGF were screened from the phage display library with monoclonal antibody GF22, which can neutralize the bio-activity of bFGF. By three rounds of screening, the positive phage clones with bFGF epitopes were selected, which can effectively block the bFGF to bind with GF22. Sequence analysis showed that the epitopes shared a highly conservative sequence (Leu-Pro-Pro/Leu-Gly-His-Phe/Ile-Lys). The sequence of PPGHFK was located at 22-27 of the bFGF. The specific immuno-response of mouse could be highly induced by phage clones with the epitopes. And the anti-bFGF activity induced by LPGHFK was 3 times higher than the original sequence, which showed that the mimetic peptide LPLGHIK might be used as a tumor vaccine in the prevention and treatment of tumor.

• Journal of Microbiology and Biotechnology
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• 제32권4호
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• pp.458-463
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• 2022

We evaluated the antibiotic susceptibilities, hemolytic activities, and technological properties of 36 Staphylococcus xylosus strains and 49 S. pseudoxylosus strains predominantly isolated from fermented soybean foods from Korea. Most of the strains were sensitive to chloramphenicol, erythromycin, gentamycin, kanamycin, lincomycin, oxacillin, tetracycline, and trimethoprim. However, 23 strains exhibited potential phenotypic acquired resistance to erythromycin, lincomycin, and tetracycline. Based on breakpoint values for staphylococci from the Clinical and Laboratory Standards Institute, >30% of the isolates were resistant to ampicillin and penicillin G, but the population distributions in minimum inhibitory concentration tests were clearly different from those expected for acquired resistance. None of the strains exhibited clear α- or β-hemolytic activity. S. xylosus and S. pseudoxylosus exhibited salt tolerance on agar medium containing 20% and 22% (w/v) NaCl, respectively. S. xylosus and S. pseudoxylosus strains possessed protease and lipase activities, which were affected by the NaCl concentration. Protease activity of S. pseudoxylosus was strain-specific, but lipase activity might be a characteristic of both species. This study confirms the potential of both species for use in high-salt soybean fermentation, but the safety and technological properties of strains must be determined to select suitable starter candidates.

• 한국초등과학교육학회지:초등과학교육
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• 제28권2호
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• pp.121-131
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• 2009

In this study, we investigated the elementary school students' perceptions toward scientific and/or technological professions in the views of accuracy, complexity, and diversity, and compared them by the students' grades and their science-related career aspiration levels. We also studied the relationships among the students' perceptions toward scientific and/or technological professions and their cognitive (science achievement), affective (enjoyment of science lessons, attitude to scientific inquiry, self-efficacy), and behavioral (participation in science-related activity) characteristics. The subjects were 369 students of 4th and 6th grades at three elementary schools in Seoul. The results revealed that the students were relatively well aware of what works and professions in science and/or technology were, but they did not have good understanding of them in the views of complexity and diversity. The 6th graders had better perceptions toward science and/or technological professions than 4th graders, although they showed the lower scores of attitude to scientific inquiry. Moreover, the higher science-related career aspirations were, the higher scores in all tests of the perceptions and the personal characteristics were. The students' perceptions toward scientific and/or technological professions were found to have relationships with their cognitive, affective, and behavioral characteristics. The multiple regression analysis of the personal characteristics on the perceptions toward scientific and/or technological professions indicated that science-related activity, science achievement, and self-efficacy were significant predictors. Educational implications are discussed.

• 기술혁신학회지
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• 제1권2호
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• pp.192-207
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• 1998

This paper focuses on the relationship between innovation and export performance of technology-based firms in Korea. This study analyses the relationship between innovative activity and firm's performances using a sample of 760 technology-based firms in Korea. As for the firm's performance indicators, export is employed. The empirical results support that innovation has a positive effect on firm's export performance. However, for small and medium firms, the relationship between innovative activity and export performance is an U-shape quadratic form, which shows that small firms takes a minimum innovative expenditure in order to access the abroad market. Also, with product differentiation, innovative firms tends to devot more to domestic market than to abroad market. Therefore, it can be concluded that innovative activity builds market power and accelerates export performance. And product differentiation through advertising expenditure make innovative firms less exporting.

• 지식경영연구
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• 제13권2호
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• pp.73-93
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• 2012

Although a wide range of theoretical researches have emphasized on the importance of knowledge management in cooperative R&D network, the empirical researches to synthetically examine the role of organizational learning and open innovation which influence on the performance of technological innovation are not enough to meet academic and practical demands. This study is to investigate the effect of open innovation and organizational learning in venture business on technological competitive advantage and establish the mediating role of organizational learning. For the purpose, the questionnaires, made based on the reviewing previous researches, were collected from 274 Korean venture businesses whose managerial focus is on developing technological innovation. As a result of analysis, the relational dimensions of open innovation - network, intensity and trust shared by a firm with external R&D partners - as well as the internal organizational learning system and competence have positive influence on building technological competitive advantage whose sub-variables are technological excellence, market growth potential and business feasibility. In addition, it is identified that organizational learning has the mediating and moderating effect in the relationship between open innovation and technological competitive advantage. These results imply that open innovation complements and expend the range of limited resources and the scope of innovation in technology-intensive small and medium-sized enterprises. Besides, organizational learning activity reinforces the use of knowledge and resources, obtained from external R&D partners. On the basis of these results, detailed issues and discussion were made in the conclusion.

• 산업경영시스템학회지
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• 제18권35호
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• pp.95-106
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• 1995

This study is aimed at development a plan to strengthen the competitiveness in technology of small and medium manufacturing enterprises, which can be assumed mainly by small and medium manufacturing companies, to improve the competitiveness of domestic industry. To remove these obstacles and strengthen the technological competitiveness, internally it is required to change the attitude of management about the development and innovation of technology first. Promotion of favorable atmosphere for the technological development and organized activity to acquire technological information are additional requirements. In conclusion, to survive the competition and to secure national industrial competitiveness, each individual company needs to endeavor for technological innovation and improvement in product quality and productivity.