• Journal of the Korean Society of Radiology
• /
• v.85 no.3
• /
• pp.596-606
• /
• 2024

Purpose To examine the technical considerations of endovascular treatment for aortoiliac occlusive disease (AIOD) based on a 10-year experience in Songklanagarind Hospital. Materials and Methods This retrospective cohort study included 210 patients who underwent endovascular treatment for symptomatic AIOD between January 2010 and December 2020. The patients' clinical and lesion characteristics, including technical considerations of the procedure, were collected, analyzed, and stratified using the Transatlantic Inter-Society Consensus (TASC). Results Most patients (80%) in this study had chronic limb-threatening ischemia lesions, with an occlusion rate of 37%. The technical success rate of TASC C & D was lower than that of TASC A & B, 84.4% vs. 99.2% p ≤ 0.001. A technical success rate of 93.3% (14/15) was found for the femoral and brachial approach, compared with a success rate of 89.0% (57/64) for the unibifemoral approach in TASC C & D, without a statistically significant difference (p = 0.076). However, the puncture site complications in this route were up to 17.6%, which is the highest rate compared with other techniques. These complications could be treated either conservatively or minimally invasively. Conclusion In cases of failed femoral access, simultaneous femoral and brachial approaches improved the technical success rate of endovascular recanalization of TASC C & D aortoiliac occlusions.

• Genomics & Informatics
• /
• v.19 no.1
• /
• pp.5.1-5.11
• /
• 2021

Head and neck squamous cell carcinoma (HNSCC) is the most frequent type of head and neck cancer that usually arises from the mucosal surfaces of several organs including nasal cavity, paranasal sinuses, oral cavity, tongue, pharynx, and larynx. The Wnt signaling pathway is a crucial mechanism for cellular maintenance and development. It regulates cell cycle progression, apoptosis, proliferation, migration, and differentiation. Dysregulation of this pathway correlates with oncogenesis in various tissues including breast, colon, pancreatic as well as head and neck cancers. The present study aims to assess the gene alterations in the Wnt family of genes so as to derive an association with HNSCC. Computational approaches have been utilized for the identification of gene alterations in the Wnt family of genes. Several databases such as cBioportal, STRING, and UALCAN were used for the purpose. The frequency of alteration was high in case of Wnt family member 11 (5%). Gene amplification, deep deletions, missense and truncating mutations were observed in HNSCC patients. There was a marked difference in the gene expression profile of WNT11 between grades as well as normal samples. The survival probability measured using the Kaplan-Meier curve also presented with a significant difference among male and female subjects experiencing a low/medium level expression. The female patients showed less survival probability when compared to the male subjects. This provides the prognostic significance of the WNT11 gene in HNSCC. Taken together, the present study provides clues on the possible association of WNT11 gene alterations with HNSCC, which has to be further validated using experimental approaches.

• Journal of the Korean Society for information Management
• /
• v.23 no.1 s.59
• /
• pp.41-62
• /
• 2006

As the research and development(R&D) has become a necessary motive in social development, the importance on the evaluation of the technical information service is also emphasized. Among others, the economical evaluation and the productivity of the technical information service are very complex and complicated as of the information value. Also the technical information service is influenced by its infrastructure. Therefore, the economical evaluation on the productivity of the technical information service requires a more systematic and complex approaches simply to be more objective and rationalized.

• Journal of Engineering Education Research
• /
• v.15 no.1
• /
• pp.9-17
• /
• 2012

Communication skills, such as writing documents and presenting technical details, are thought to be essential for modern engineers. Engineering students usually have less interest in writing and presentation than their humanities student counterparts and their concerns are different, too. So it is necessary to teach them in a different way which is suited to them. However, teaching such subjects has been a tricky problem for educators in terms of teaching methods. Also, to teach writing and presentation effectively for engineering students, collaboration between the faculties of different disciplines is necessary because each discipline has its own specific domain knowledge and approaches. But many unsolved problems exist with regard to how to deal with the technical and administrative aspects, and so on. This paper introduces one case in the education of technical writing and presentation, which is a collaboration between an engineering faculty and a faculty of literature. The literature faculty conducts basic education and training for writing skills, while the engineering faculty teaches the technical aspects of documentation, as well as presentation skills. The focus is placed on topics such as self-introduction, searching technical literature and materials, describing and explaining things and presentation practice, etc. During the class there is cooperation in each topic domain, while the faculties collaborate in teaching and evaluation.

• World Technopolis Review
• /
• v.4 no.2
• /
• pp.62-78
• /
• 2015

The importance of university technology transfer has widely been brought to the center of attention over the last decades. Research and practice thereby often concentrate on issues related to patenting and licensing or entrepreneurship but abstract away from relationship- and network-focused initiatives. In this paper, we argue that efforts to systematically develop close, long-term collaboration partnerships - although complex and resource intensive - are likely to be more beneficial for both universities and industry in the long run. Drawing on data derived from interviews with technology transfer executives of 22 leading European and U.S. universities, we analyze and discuss well-established practices of network and relationship management and their possible impact on technology transfer success. Our findings indicate that dedicated relationship management approaches can yield a sustainable competitive advantage for universities. We thereby shift the focus away from transaction-orientation towards more forward-looking relationship-centric approaches and discuss their institutionalization in great detail.

• IE interfaces
• /
• v.9 no.2
• /
• pp.191-202
• /
• 1996

A variety of approaches on performance evaluation modeling have appeared in the technical literature for flexible manufacturing systems(FMS) which can be evaluated only through computer simulation. This study represents a comparative approach for FMS performance evaluation modeling based on reliability, availability and maintainability, and life cycle cost. The methodology proposed in this research includes the following three-step generative approaches. First, a static model to find the initial system configuration is considered under the assumption that the system availability is given as one (failure and maintenance are not considered), and in second step, a stochastic simulation is proposed to serve as a performance evaluation model for FMS with stochastic failure and repair time. In the last step, we developed a simulation modeling using a simulator, FACTOR/AIM to consider a variety of performance factors and dynamic behavior of FMS. Also the applicability and validity of the proposed approaches has been tested and compared through the results of a sample problem using computer programs and procedures developed in each step.

• Structural Engineering and Mechanics
• /
• v.26 no.2
• /
• pp.191-210
• /
• 2007

The three different approaches (reformulations) of evolution strategies (ESs) have been proposed in the literature as extensions of the technique for solving discrete problems. This study implements an extensive research on application, evaluation and comparison of them in discrete optimum design of steel frames. A unified formulation is first developed to explain these approaches, so that differences and similarities between their inherent search mechanisms can clearly be identified. Two examples from practical design of steel frames are studied next to measure their performances in locating the optimum. Extensive numerical experimentations are performed in both examples to facilitate a statistical analysis of their convergence characteristics. The results obtained are presented in the histograms demonstrating the distribution of the best designs located by each approach. In addition, an average improvement of the best design during the course of evolution is plotted in each case to compare their relative convergence rates.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.28 no.4
• /
• pp.41-47
• /
• 2005

This paper presents the practical goals and approaches to drive forward informatization of small and medium enterprises(SMES). The presented goals such as productivity, duedate, production cost, and quality measurements are used effectively in the previous diagnosis and the post evaluation for the business of the informatization. As the practical approaches to improve these goals, This study considers the importance of balancing, sequencing, and scheduling. These methods ease the congestion of production sites of SMES with insufficient competitiveness and can contribute to the promotion of informatization that improves productivity and cuts down the cost of production effectively.

• Journal of Chest Surgery
• /
• v.55 no.4
• /
• pp.301-306
• /
• 2022

Surgical approaches to lung transplantation in adults vary substantially among surgeons and institutions, but the underlying principles are consistent. This article provides a surgical overview of bilateral sequential lung transplantation.

• 한국정보디스플레이학회:학술대회논문집
• /
• 2006.08a
• /
• pp.524-524
• /
• 2006

For decades, the pursuit of volume commercialization of low-power reflective displays with a paper-like look has been an unfulfilled dream. While steady technical progress was made throughout the late 1990s, there were still no volume products incorporating electronic paper displays (EPD) on the market. Now, microencapsulated electrophoretic display technology, also called electronic ink, has moved into volume production with a frontplane laminate (FPL) display component called E Ink Imaging Film™. This film is coated roll to roll on a flexible plastic substrate and integrated into a display module. Today, all-plastic segmented displays are being shipped as well as displays with electronic ink FPL being driven by glass TFT backplanes. A roadmap to active matrix flexible electrophoretic displays is being enabled by rapid technical progress on flexible TFT backplanes by a variety companies. Each of the approaches to these backplanes and flexible active matrix displays has different advantages for the various market segments being pursued including large format flexible displays for e-news and other reader applications, rollable displays for compact readers, and high resolution small format displays up to 400 ppi that can have fully integrated drive electronics to reduce size and drive down costs. Backplane approaches include Si on plastic, organic transistors on plastic, and Si transistors on flexible stainless steel substrate. Progress is also being made on next generation inks, including more reflective inks with higher contrast ratios. A full color 6 inch, 170 pixel per inch (PPI) active matrix display using a newer generation ink has been developed and this will be described and demonstrated. Large format segmented flexible displays will also be described.