• Archives of Pharmacal Research
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• 제27권6호
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• pp.670-675
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• 2004

Since the bitter taste of enrofloxacin apparently limit the patient compliance in the oral formulations of the antibacterial agent, the masking of the taste is essential for the improvement of the therapeutic effectiveness. Therefore, this study was carried out to examine the feasibility of taste masking of enrofloxacin by the retardation of its dissolution rate using the formation of complex between the drug and Carbopol. The complexation between Carbopol and enrofloxacin was confirmed by turbidity, UV spectrophotometry, wide angle X-ray diffraction, and differential scanning calorimetry. The enrofloxacin content in the complexes was 34％ （Carbo-enrofloxacin complex I） and 57％ （Carbo-enrofloxacin complex II） depending on the prepara-tion method. The dissolution rate of enrofloxacin from the complex increased as the pH was reduced. The dissolution rate of enrofloxacin from the Carbo-enrofloxacin complex I was significantly lower than that of the enrofloxacin powder. Therefore, these observations suggest that Carbo-enrofloxacin complex I can be used to mask the taste of enrofloxacin.

• 상하수도학회지
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• 제22권2호
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• pp.227-232
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• 2008

The masking effect of chlorine on algae-related taste and odor(T&O) compounds has long been an important issue for water suppliers. In this study, masking experiments with chlorine were performed on two kinds of treated water and one of raw water. After adding chlorine(0 to 0.8 mg/L) to water samples, odor intensity was evaluated by a newly developed sensory method(2-out-of-5 odor test) for three days along with the measurement of residual chlorine concentration. Even though the relationship between the residual chlorine concentration and odor reported by the sensory analysts was not always coincident, it was proved that residual chlorine more than a certain concentration could completely mask both added geosmin and naturally occurring T&O compounds. For the sand-filtered water spiked with 10 ng/L of geosmin, 0.12-0.18 mg/L of residual chlorine was necessary to achieve complete masking. In the case of GAC-filtered water, 10 ng/L of spiked geosmin was completely masked by 0.15-0.1 mg/L of residual chlorine. Combined ozone and GAC was not enough to treat raw water spiked with 300 ng/L of geosmin. In this experiment, sensory analysts were able to detect earthy or musty odors from the treated water. From a masking experiment with raw water taken from the Daechung Reservoir, it was found that fishy odor was more difficult to mask with chlorine than earthy odor. As the chlorine residual declined, the analysts began to notice the original odor and the fishy odor was noticed earlier than the earthy odor.

• Journal of Pharmaceutical Investigation
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• 제40권3호
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• pp.161-166
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• 2010

A fast dissolving tablet was developed using the freeze-drying technique. Hyeonggaeyeongyotang was selected as a model oriental medicine. Formulation and processing parameters were studied to obtain freeze-dried tablet with high drug loading, good palatability, and fast disintegration time. $Kollidon^{(R)}$ CLM served as both matrix former and taste masking agent. Ethanol used as co-solvent, decreased the disintegration time of tablet. Aspartame was employed to impart better taste. Drying condition was found to have a major effect in the morphology of the tablets. Freeze-drying process was optimized to decrease the processing time and improve the appearance of the tablets.

• 한국산학기술학회논문지
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• 제4권3호
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• pp.279-283
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• 2003

향신료로 널리 사용되는 마늘을 이용하여 마늘 특유의 맛과 향을 조절하여 쉽게 음용할 수 있는 tea-bag type침출차를 제조하는 방법을 개발하였다. 주재료인 마늘은 생마늘을 고온에서 구운 것보다 50℃에서 건조한 분말을 사용하는 것이 관능적으로 우수하였다. 단맛의 소재로 당전이 스테비아 감미료를 사용하여 마늘의 맛과 향을 masking할 수 있는 첨가물을 선발하였다. 그 결과 최종적으로 녹차, 둥굴레, 칡이 선발되었으며, 이들을 2종류씩 혼합한 경우 masking 효과는 두 종류의 부재료를 동량으로 사용한 실험구가 우수하였다. 마늘의 농도는 건조분말로 20∼30%, 스테비아 감미료의 농도는 1％가 적당하였다. 총 3종류의 formulation을 확립하였으며 관능적으로도 큰 차이는 없었다. 시판중인 현미녹차와 품질(색도, 탁도, 고형분 농도)을 비교한 결과 색도는 현미녹차가, 탁도와 고형분 농도는 마늘차가 우수하였다.

• 한국식품과학회지
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• 제31권6호
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• pp.1477-1483
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• 1999

양파의 향기성분을 보존 또는 제거할 목적으로 양파냄새를 masking하거나 제거하는 물질을 양파즙에 처리하여 관능검사를 실시하였고, pyruvate와 thiosulfinate를 측정하였으며 Solid Phase Micro Extraction(SPME)/GC법을 이용하여 휘발성 향기성분의 변화를 조사하였다. 생양파즙의 주요 향기성분은 dipropyl tetrasulfide, 1-propenyl propyl trisulfide, methyl propyl trisulfide, dipropyl trisulfide 등이었다. 다시마, 미역, 김, 규조토를 첨가한 양파즙의 휘발성 향기성분은 대조군과 비교하였을 때 모든 향기성분이 다소 감소하는 경향이었으나 활성탄과 ${\beta}-cyclodextrin$ 첨가군은 거의 모든 향기성분이 제거되었다. 여러 가지 첨가물의 농도를 달리하여 양파즙에 첨가하여 관능검사를 실시한 결과 양파 냄새는 감소하였으며 p<0.05 수준에서 유의적으로 차이가 나타났다. 해조류를 첨가한 군의 pyruvate와 thiosulfinate 함량은 대조군과 차이가 없었으나 활성탄을 첨가한 양파즙의 경우, 그 함량이 크게 감소하였다. 이상의 결과, 다시마, 미역, 김 등의 해조류 처리군은 양파의 향기성분과 매운맛 성분을 보존하면서 관능적으로 양파냄새를 masking하는 효과를 나타내었고, ${\beta}-cyclodextrin$과 활성탄은 양파에 존재하는 많은 휘발성 향기성분과 복합물을 형성하거나 홉착하여 양파냄새를 제거한 것으로 사료되어 진다.

• 한국조리학회지
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• 제5권1호
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• pp.131-148
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• 1999

Cheju's local foods are various but Island being geographically surrounded by water, sea-foods play a greater part in the diet that is quite different from the mainland Most of dishes are prepared from local foods and the marine products. That traditional food that have been developed through the lifestyle are now becoming the great interest to both foreign and domestic guests. In this research, we have concluded that developing a cheju's traditional food manu and local manu cooking method. 1. Improvement of cooking method. - development of cheju's traditional Food material and spice. 2. Use not raw fish - boiling, grilling, frying 3. Improvement of cheju's local Food's name. 4. Use the only Boneless fish. 5. taste reformation of Fermentation Food - Masking the TMA etc. 6. Use the many Spice in local food.

• 한국식생활문화학회지
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• 제22권2호
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• pp.274-282
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• 2007

This study was performed to make new products rising Pimpinella brachycarpa N., one of the Korean aromatic medicinal plant called chamnamul, which is a perennial plant of the Umbelliferae family. New products were natural chamnamul spice, chamnamul soup, chamnamul tea, and chamnamul mook as functional foods. The masking effect of Pimpinella brachvcarpa N., on fishy and meaty odor were investigated to test the usefulness of chamnamul as a natural spice. It could be concluded that the effect of added amounts of chamnamul on the cream soup increases the taste and appearance, and improves the flavor and color by the sensory evaluation. The chamnamul tea prepared by a filtration method is better than that by a leaching method on the preference test. In the texture properties of chamnamul mooks by a texture analyzer (XT-RA, Texturometer), the cohessiveness of them was higher than that of the white one.

• 한국식생활문화학회지
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• 제16권5호
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• pp.470-477
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• 2001

마늘이 김치의 숙성과 품질에 미치는 영향을 조사하고 아울러 cyclodextrin과 sorbitol의 마늘냄새 masking 효과를 실험하였다. 김치 숙성 초기의 산도는 마늘 첨가량이 많을수록 대조구 비해서 높았고 환원당 함량은 마늘 첨가량이 많을수록 높았으나 숙성말기에는 거의 비슷한 수준을 유지하였다. 미생물수의 경우 숙성초기에는 마늘 첨가에 의해 성장이 촉진되었으나 이후에 그 수준을 유지한 후에는 대조구에 비해서 오히려 억제되었다. 관능검사 결과는 온도에 관계없이 마늘을 첨가하지 않은 김치가 모든 관능적인 면에서 유의적으로 나쁘게 평가되었으며 마늘을 $2{\sim}3%$ 첨가한 김치가 유의적으로 가장 좋게 평가되었다. Cyclodextrin 또는 sorbitol을 1%씩 첨가한 결과 마늘맛을 masking하는데는 효과가 없었고 관능적으로도 나쁘게 평가되었다.

• 한국식품저장유통학회지
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• 제14권6호
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• pp.605-610
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• 2007

구아바 잎을 이용한 가공제품개발의 기초자료를 마련하고자 구아바 잎을 발효, 증숙 및 볶음 처리하여 품질특성을 살펴보았다. 그 결과 총 페놀성 화합물 함량의 경우 볶음 처리한 것이 높게 나타났으며, tyrosinase 저해활성 및 전자공여능은 증숙 처리한 것이 우수한 것으로 나타났다. 또한 전반적인 기호도에 있어서는 발효 및 증숙 처리한 것이 우수한 것으로 나타났다. 한편 데침 및 증숙 처리 시간에 따른 품질특성을 살펴본 결과, 총 페놀성 화합물 함량, tyrosinase 저해활성 및 전자공여능은 처리시간이 길어질수록 전반적으로 감소하는 경향이었으며, 증숙 처리한 것이 데침 처리한 것에 비해 우수한 것으로 나타났다. 데침 및 증숙 처리된 구아바 잎의 관능검사 결과, 통계적으로 유의적인 차이가 없었으나, 구아바 잎의 떫은맛으로 인해 전반적으로 관능평점이 낮게 나타났다. 따라서 구아바 잎을 사용한 가공제품 개발에서는 떫은맛을 감소시킬 수 있는 방안의 연구가 필요한 것으로 나타났다.

• 동아시아식생활학회지
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• 제20권6호
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• pp.888-895
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• 2010

Riceyeotgangjung (RYG) with added spirulina was prepared with citron juice for masking of odor. Oil temperature for puffing was found to be $220^{\circ}C$ for frying dry rice based upon the results of expansion rate and color. RYGs with added spirulina (1, 2, and 3%) were prepared under the above conditions, and their physicochemical and sensory properties were examined under storage at $60^{\circ}C$ for 15 days. Moisture content of RYG decreased proportionally with the spirulina content and storage time. The hardness levels of the freshly made RYGs with spirulina were higher than that of control. During storage, the hardness of the control gradually increased, but those of the RYGs with spirulina gradually decreased, although no significant differences existed between the spirulina containing RYGs. Lightness and redness values in the Hunter color system decreased according to the spirulina content and storage time. Yellowness value also increased with the spirulina content and storage time. Phycocyanin and total phenolic content increased with spirulina content, but decreased with the storage period. Sensory evaluation results showed that RYG with 2% added spirulina received the highest scores for color, taste, overall acceptability, and intention of purchase. As a result, the optimal addition amount of spirulina to RYG is recommended to be 2%.