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Effect of Leonurus japonicus Houtt. on Scopolamine-induced Memory Impairment in Mice (Scopolamine 유발 기억 손상 마우스에서 익모초의 효과)

  • Lee, Jihye;Kim, Hye-Jeong;Jang, Gwi Yeong;Seo, Kyung Hye;Kim, Mi Ryeo;Choi, Yun Hee;Jung, Ji Wook
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.34 no.2
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    • pp.81-87
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    • 2020
  • Cognitive impairment is symptoms of dementia, a degenerative brain disease that is drawing attention in a rapidly aging society. This study was conducted to investigate the improvement of cognitive function of Leonurus japonicus on scopolamine-induced memory impairment in mice and the effect and mechanism of memory recovery. In vivo studies were conducted on mice orally pretreated with L. japonicus in doses of 50, 100 and 200 mg/kg (p.o.) and scopolamine (1 mg/kg, i.p.) were injected 30 min before the behavioral task. Antioxidant activity was assessed by 2,2-diphenyl-1-picryl hydrazyl (DPPH) assay and 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay, and acetylcholinesterase (AChE) inhibition activity evaluated by Ellman's method. In behavior studies showed that L. japonicus has an improved the memory of scopolamine-treated mice in Y-maze, passive avoidance and Morris water maze test. In addition, L. japonicus was also exerted free radical scavenging activity and inhibited acetyl cholinesterase activity. These results suggest that L. japonicus improves short-term and long-term memory in scopolamine-induced memory decline model and prevents scopolamine-induced memory impairments through in reduced oxidative stress and acetyl cholinesterase inhibition effect. Thus, L. japonicus is related to functional medicinal materials for prevention and treatment of human dementia patients.

Effects of Examiner's Verbal Feedback on Nursing Students' Accuracy of Self-assessment, Emotional Response, Self-efficacy, and Perceived Quality of Feedback in Skill Performance Assessment (술기 수행 평가에서 평가자의 유형별 피드백이 간호대학생의 자가 평가의 정확성, 정서반응, 자기효능감, 인지하는 피드백의 질에 미치는 효과)

  • Kim, Eun Jung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.25 no.2
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    • pp.146-154
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    • 2018
  • Purpose: In this study, effects of positive, negative, and mixed verbal feedback were examined for accuracy of self-assessment, emotional responses, self-efficacy, and perceived quality of feedback in skill performance assessment. Methods: Participants were a convenience sample of 104 second-year nursing students who had completed their fundamentals of nursing class. Participants were assigned randomly to a positive, a negative or a mixed feedback group. All participants completed the performance measure and then received the assigned the type of feedback from an evaluator. After delivery of feedback, they assessed their own performance using the same sheet as the evaluator and completed the survey for emotional response, self-efficacy for learning, and quality of feedback. Results: There were no significant differences in accuracy of self-assessment and perceived quality of feedback among the three groups ($x^2=4.74$, p=.094; $x^2=3.30$, p=.192, respectively). The negative feedback group had significantly lower self-efficacy and positive emotions and more negative emotions than the other two groups (F=9.43, p=.009; $x^2=16.29$, p<.001; $x^2=5.69$, p=.005, respectively). Conclusion: Negative feedback can affect emotions and motivations for learning in nursing students and may interfere with the effectiveness of feedback, so instructors should pay more attention when providing negative feedback. Mixed feedback with an effect similar to positive feedback could be an alternative.

Investigation of the 7th Grade Science-gifted Students' Understanding about the Lunar Phase through Their Own Observation and Interpretation

  • Kim, Eun-Sook;Yu, Hee-Won;Choe, Seung-Urn
    • Journal of the Korean earth science society
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    • v.32 no.5
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    • pp.514-520
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    • 2011
  • As homework, a total of 32 seventh grade science-gifted students were asked to observe the moon at daily intervals for one month duration. They were also asked to take the photos and to record relevant variables in a given format. The purpose of the task was to investigate what students thought, as they observed the moon. The results show that students paid attention mainly to the position of the moon relative to other variables such as the date in the lunar calendar, the observer's position on the earth, and the position of the sun. Overall students' response implied that students did not observe the lunar phase in relation with relevant variables. Some reponses from students show common misconceptions such as the cause of the lunar phase to reflect the shadow of the earth. However, some responses reveal students' idea that has been rarely reported in the previous researches. For example, some students drew the moon to revolve in the opposite direction. Significant number of students drew the sun's position to be due west before the full moon and due east after the full moon. Few students recognized the relation between the time of observation and observer's position on the earth. The results of current research suggest that not only the education but also the research needs to be expanded to consider informal environment such as the actual field conditions.

A Critical Evaluation of the Concept and Writing of Learning Outcomes (학습성과의 개념과 작성에 대한 탐구)

  • Lee, Dong Yub;Yang, Eunbae B.
    • Korean Medical Education Review
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    • v.18 no.3
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    • pp.125-131
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    • 2016
  • Recent changes in educational paradigms that emphasize the performance or outcomes of education are redefining how learning objectives are being described as 'learning outcomes' in various academic disciplines. Medical education is not an exception to this trend. However, it has come to our attention that the key concepts and appropriate descriptions of learning outcomes have not been well understood among educators and that this lack of understanding has hindered our efforts to implement the practice in the field. This study aims to provide a direction to establish and describe learning outcomes by examining previous studies that have focused on setting learning objectives as well as learning outcomes. Setting and describing learning outcomes starts from reflection on the approach of behavioral learning objectives, which overemphasizes learner's acquired knowledge, skills, and attitude in each classroom rather than actual performance. On the other hand, the learning outcome approach focuses on what the learner is able to do as a result of a learning experience. This approach is more learner-friendly and encourages students to lead and be responsible for their learning process. Learning outcomes can best be described when the relevance of actual contexts and the hierarchy of learning objectives are considered. In addition, they should be in the form of context, task, performance, and level, as well as be planned with proper assessment and feedback procedures. When these conditions are met, the learning outcome approach is beneficial to students as it presents a curriculum that is more open to learners. Despite these advantages of the learning outcome approach, there is a possible concern that setting the learning outcomes and describing them can restrict evaluation to lower cognitive skills if the concept of learning outcome is narrowly interpreted or is set too low. To avoid such narrow applications, it is important for educators to understand the comprehensiveness of the learning outcome setting and to consider long-term outcomes embedded in an organizational vision rather than only short-term behavioral outcomes.

Collaboration through the Asia Pacific MPS Network (APMN), Asia Pacific MPS Registry (APMR), and Association for Research of MPS & Rare Diseases (ARMRD)

  • Cho, Sung Yoon
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.1 no.1
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    • pp.2-4
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    • 2015
  • Though the rate of incidence of each rare disease, including mucopolysaccharidosis (MPS), is low, this is not the case if they are taken as a whole. Rare diseases often have genetic causes and vary in type. However, the signs and symptoms vary greatly by disease, making it difficult to make accurate diagnoses and conduct necessary research, which is why we believe it is a field that deserves more attention and research. It is important to establish an infrastructure of experts in each country and promote cooperation within the Asia-Pacific region in order to improve specialist training and communication. Given the need for a system of cooperation, the Asia Pacific MPS Network (APMN) was established by several MPS experts in South Korea, Japan, and Taiwan in January 2013. Thereafter, the Asia Pacific MPS Registry (APMR), an electronic remote data system, was established by the APMN. Then, the Association for Research of MPS & Rare Diseases (ARMRD), an academic society that supports research on MPS and other rare diseases, was established by President Dong-Kyu Jin in April in 2015. The main task of the ARMRD is to support APMN-related work. The ARMRD published a uniform guideline that reflects the characteristics and circumstances of local patients through the Korean MPS Expert Council. Now, the APMN, APMR, and the annual Korean MPS Symposium are supported by ARMRD. Organizations like the APMN and APMR are necessary because international cooperation and collaboration are needed to conduct clinical trials on those diseases. ARMRD members hope to encourage the interest of experts and researchers of MPS & rare diseases as well as active participation in the research and treatment of patients suffering from rare diseases, including MPS, to ultimately improve the quality of life of the patients as well as their families.

A Study on the Mode of Address and Meaning Creation of Underlight in Broadcasting Lighting (방송조명에서 언더라이트의 표현 양식과 의미 창출에 관한 연구)

  • Kim, Young-Jin;Park, Gooman
    • Journal of Broadcast Engineering
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    • v.21 no.5
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    • pp.749-759
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    • 2016
  • As image contents in broadcasting have been created in HDTVs and monitors have been commercialized, facial expression of objects in broadcasting lighting has become a very significant task. Figure modeling of objects in HDTVs requires smoother and cleaner video images owing to the expansion of precision of image expression by light. Lighting methods that enlighten characters in the digital generation have come to require a new change. Character modeling methods used on expression features of underlight are receiving attention for aesthetic expression of figures in HD images. Accordingly, the influence of underlight light source intensity, distance, and size on character modeling characteristics was experimentally measured and comparatively analyzed. The experiment results show that good results can be obtained only when the intensity is 17%∼25.5% in contrast to total brightness, distance is beyond 40cm, and the size is at least 20cm, to exhibit the optimum effect of underlight. This data will become material with high usage to gain smoother and cleaner images of characters in future high-quality images.

An Implementation of Network Intrusion Detection Engines on Network Processors (네트워크 프로세서 기반 고성능 네트워크 침입 탐지 엔진에 관한 연구)

  • Cho, Hye-Young;Kim, Dae-Young
    • Journal of KIISE:Information Networking
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    • v.33 no.2
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    • pp.113-130
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    • 2006
  • Recently with the explosive growth of Internet applications, the attacks of hackers on network are increasing rapidly and becoming more seriously. Thus information security is emerging as a critical factor in designing a network system and much attention is paid to Network Intrusion Detection System (NIDS), which detects hackers' attacks on network and handles them properly However, the performance of current intrusion detection system cannot catch the increasing rate of the Internet speed because most of the NIDSs are implemented by software. In this paper, we propose a new high performance network intrusion using Network Processor. To achieve fast packet processing and dynamic adaptation of intrusion patterns that are continuously added, a new high performance network intrusion detection system using Intel's network processor, IXP1200, is proposed. Unlike traditional intrusion detection engines, which have been implemented by either software or hardware so far, we design an optimized architecture and algorithms, exploiting the features of network processor. In addition, for more efficient detection engine scheduling, we proposed task allocation methods on multi-processing processors. Through implementation and performance evaluation, we show the proprieties of the proposed approach.

A Business Service Identification and Quality Evaluation Using Enterprise Architecture (전사적 아키텍처 기반 비즈니스 서비스 식별 및 품질평가)

  • Jung, Chan-Ki;Hwang, Sang-Kyu;Byun, Young-Tae
    • The KIPS Transactions:PartD
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    • v.17D no.5
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    • pp.347-352
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    • 2010
  • Automatic service identification and quality evaluation is one of key characteristics for a Service-Oriented Computing, being receiving a lot of attention from researchers in recent years. However, most researchers focus on identifying and evaluating application services and do not present methods for automatically identifying and evaluating business services from business processes. In general, the manual business service identification process by a human expert is a highly expensive and ambiguous task and may result in the service design with bad quality because of errors and misconception. We propose an automatic business service identification and quality evaluation method using Enterprise Architecture as a machine understandable knowledge-base. We verify the effectiveness of the proposed method through a case study on Department of Defense Enterprise Architecture.

Web Information Retrieval Exploiting Markup Pattern (마크업 패턴을 이용한 웹 검색)

  • Kim, Min-Soo;Kim, Min-Koo
    • Journal of KIISE:Computing Practices and Letters
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    • v.13 no.6
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    • pp.407-411
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    • 2007
  • Over the years, great attention has been paid to the question of exploiting inherent semantic of HTML in the area of web document retrieval. Although HTML is mainly presentation oriented, HTML tags implicitly contain useful semantics that can be catch meaning of text. Focusing on this idea. in this paper we define 'markup pattern' and try to improve performance of web document retrieval using markup patterns. Markup pattern is a mirror of intends of web document publisher and an internal semantic of text on web document. To discover the markup pattern and exploit it, we suggest a new scheme for extracting concepts and weighting documents. For evaluation task, we select two domains-BBC and CNN web sites, and use their search engines to gather domain documents. We re-weight and re-score documents using proposed scheme, and show the performance improvement in the two domains.

A Survey on the Comprehension of Graphs of Sixth Graders (초등학교 6학년 학생들의 그래프 이해 능력 실태 조사)

  • Hwang, Hyun-Mi;Pang, Jeong-Suk
    • School Mathematics
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    • v.9 no.1
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    • pp.45-64
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    • 2007
  • The primary purposes of this study were to investigate how sixth graders would react to the types of tasks with regard to the comprehension of graphs and what differences might be among the kinds of graphs, and to raise issues about instructional methods of graphs. A descriptive study through pencil-and-paper tests was conducted. The tests consisted of 48 questions with 4 types of tasks (reading the data, reading between the data, reading beyond the data, and understanding the situations) and 6 kinds of graphs. The conclusions drawn from the results obtained in this study were as follows: First, it is necessary to foster the ability of interpreting the data and understanding the situation in graphs as well as that of reading the data and finding out the relationships in the data. Second, it is informative for teachers to know students' difficulties and thinking processes. Third, in order to develop understanding of graphs, it is important that students solve different types of tasks beyond simple question-answer tasks. Fourth, teachers need to pay attention to teach fundamental factors such as reading the data with regard to line graphs and stem-and-leaf plots Finally, graph type and task type interact to determine graph-comprehension performance. Therefore, both learning all kinds of graphs and being familiar with multiple types of tasks are important.

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