• Journal of Korean Philosophical Society
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• 제146권
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• pp.1-24
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• 2018

The purpose of this paper is to explore the meaning of theoretical ethics regarding bioethics. First, I explore the meanings and limitations of the bioethics domain for 'the principle of equal consideration of interests' and the 'preference utilitarianism' concepts Singer presents. Secondly, I emphasize the significance of Kant's ethics in the domain of bioethics. Lastly, I suggest that Aristotle's virtue ethics should be realized in the domain of bioethics. Furthermore, I would like to suggest the meaning of human life through this. Singer's argument brings up a new topic about the meaning of evolved life not considered in the history of traditional ethics. He presented undeniable opinions about human dignity that he took for granted. In addition, it is assessed that the scope extension for the life respect target has been reasonably achieved. Contrary to this, Kant's ethics explains the meaning of human dignity based on its metaphysical meaning. Furthermore, it provides an appropriate orientation for human life. Embracing their claims is not sufficient to explain the meaning of Good Life. The meaning of Good Life is likely to be resolved through the application of Aristotle's virtue ethics. The meaning of a being of substance is living and furthermore, it is inherent to being itself.

• Smart Structures and Systems
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• 제24권5호
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• pp.567-585
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• 2019

In the past two decades, structural health monitoring (SHM) systems have been widely installed on various civil infrastructures for the tracking of the state of their structural health and the detection of structural damage or abnormality, through long-term monitoring of environmental conditions as well as structural loadings and responses. In an SHM system, there are plenty of sensors to acquire a huge number of monitoring data, which can factually reflect the in-service condition of the target structure. In order to bridge the gap between SHM and structural maintenance and management (SMM), it is necessary to employ advanced data processing methods to convert the original multi-source heterogeneous field monitoring data into different types of specific physical indicators in order to make effective decisions regarding inspection, maintenance and management. Conventional approaches to data analysis are confronted with challenges from environmental noise, the volume of measurement data, the complexity of computation, etc., and they severely constrain the pervasive application of SHM technology. In recent years, with the rapid progress of computing hardware and image acquisition equipment, the deep learning-based data processing approach offers a new channel for excavating the massive data from an SHM system, towards autonomous, accurate and robust processing of the monitoring data. Many researchers from the SHM community have made efforts to explore the applications of deep learning-based approaches for structural damage detection and structural condition assessment. This paper gives a review on the deep learning-based SHM of civil infrastructures with the main content, including a brief summary of the history of the development of deep learning, the applications of deep learning-based data processing approaches in the SHM of many kinds of civil infrastructures, and the key challenges and future trends of the strategy of deep learning-based SHM.

• Journal of Lipid and Atherosclerosis
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• 제7권2호
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• pp.122-154
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• 2018

Familial hypercholesterolemia (FH) is typically associated with single gene mutation that is inherited by autosomal dominant manner. Due to high cardiovascular risk, aggressive discovery, diagnosis, and treatment of FH are critical. Although FH is being increasingly spotlighted, we do not have sufficient data on Korean patients with FH. Here, we present the content of symposium of the Education Committee, Korean Society of Lipid and Atherosclerosis held in May 2018: 1) epidemiology, clinical diagnosis, Korean FH data, and regulation in Korea; 2) genes associated with FH, sequencing process in suspicious proband, cascade screening, and difficulty in genetic diagnosis in FH; 3) the importance of lipid-lowering therapy in FH, conventional and novel therapeutics for FH; 4) diagnosis of FH in children and adolescence, screening, and treatment of FH in children and adolescence; 5) history of FH studies in Korea, the structure and current status of FH registry of Korean Society of Lipid and Atherosclerosis; and 6) difficulty in diagnosis of heterozygous and homozygous FH, drug intolerance and achievement of treatment target. Discussion between speakers and panels were also added. We hope that this article is helpful for understanding FH and future studies performed in Korea.

• Journal of the Korean Society of Child Welfare
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• 제58호
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• pp.47-76
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• 2017

This study aimed to examine how strictly child-related sexual crimes were sentenced in Korea. The target cases of the study included eight cases that were appealed to the Supreme Court between 2000 and 2015. The main findings of the assessment of the eight cases indicated that there were sentences with lower terms than laws regarding sexual crimes against children. While laws should be strictly applied to cases of sexual crimes against children, the level of penalty was found to be relatively generous compared to the applicable laws. In particular, the reason for the crimes, the lack of any history of sexual crimes by the perpetrator, the perpetrator's relationship with the child victim, forgiveness from the children, and regret of the perpetrator were found to reduce sentences. Comparatively, the exploitation of parent status, the accusation of the perpetrator, and the lack of mutual consent were factored in consideration of harsher sentences. The findings suggest that it is necessary to reexamine the levels of sentences related to sexual crimes against children.

• Entomological Research
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• 제48권6호
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• pp.533-539
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• 2018

The RNA interference (RNAi) has been considered as an important genetic tool and applied to develop a new living modified (LM) crop trait which is an improvement of nutrient quality or pest management. The RNAi of DvSnf7 has been used for resistance to LM maize and the Western Corn Rootworm which is a major agricultural pest for the US Corn Belt. Most of the environmental risk assessments (ERA) of double strand RNA (dsRNA) have been performed using in vitro transcript products, and not in vivo expressed product. A large amount of dsRNA was required for the acute toxicity assay of water fleas. Therefore development of massive dsRNA purification techniques is critical. Daphnia, a freshwater microcrustacean, is a model organism for studying cellular and molecular mechanism involved in life history traits and ecotoxicology. In this study, we established the massive dsRNA purification method using Escherichia coli and implemented acute toxicity assays to Daphnia magna. As a result, the present RNase A and DNase I, dsRNA was efficiently purified without any special techniques or equipment. Even though purified dsRNA existed during the acute toxicity test, lethality or abnormal behavior were not observed in D. magna. These results indicated that GFP and DvSnf7 dsRNA were not significantly affected to D. magna due to their lack of sequence matching in its genome. The purification method of dsRNA and the acute toxicity assay of water fleas using purified dsRNA would be suitable for the toxicological studies of LMOs to aquatic non-target organisms.

• Journal of the Korea institute for structural maintenance and inspection
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• 제23권1호
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• pp.63-70
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• 2019

The number of vehicle-to-barrier collisions has increased due to improved driving environments. In addition, it is reported that the number of accidents led to impact severity larger than current capacity of a median barrier has increased. It is required to develop a high performance median barrier in order to secure expressway safety. This paper aims at proposing impact loading model and locations for a high performance median barrier based on analysis of median-barrier-related accident history. The SB6 test level (Impact severity: 420 kJ, Mass: 25 ton, Impact speed: 80 km/h, Impact angle: $15^{\circ}$) was suggested for target impact severity based on statistical data analysis. The suitable locations also were proposed from investigation of driver behaviors for installation and rehabilitation of high performance median barrier.

• Journal of the Earthquake Engineering Society of Korea
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• 제23권3호
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• pp.149-157
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• 2019

The purpose of this study is to investigate the effects of the significant duration of ground motions on responses of base-isolated nuclear power plants (NPPs). Two sets of ground motion records with short duration (SD) and long duration (LD) motions, scaled to match the target response spectrum, are used to perform time-history analyses. The reactor containment building in the Advanced Power Reactor 1400 (APR1400) NPP is numerically modeled using lumped-mass stick elements in SAP2000. Seismic responses of the base-isolated NPP are monitored in forms of lateral displacements, shear forces, floor response spectra of the containment building, and hysteretic energy of the lead rubber bearing (LRB). Fragility curves for different limit states, which are defined based on the shear deformation of the base isolator, are developed. The numerical results reveal that the average seismic responses of base-isolated NPP under SD and LD motion sets were shown to be mostly identical. For PGA larger than 0.4g, the mean deformation of LRB for LD motions was bigger than that for SD ones due to a higher hysteretic energy of LRB produced in LD shakings. Under LD motions, median parameters of fragility functions for three limit states were reduced by 12% to 15% compared to that due to SD motions. This clearly indicates that it is important to select ground motions with both SD and LD proportionally in the seismic evaluation of NPP structures.

• Journal of the Korean Society of Environmental Restoration Technology
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• 제23권6호
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• pp.151-166
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• 2020

Various experience keywords were derived through text mining analysis of two National Ecological and Cultural Exploration Routes. The results of this study were drawn as follows: The interaction between the experience keywords was analyzed by the degree centrality, closeness centrality, and betweenness centrality value calculated through the centrality analysis of the research site experience keywords. First, In the text mining analysis, 'walking' appeared as the top keyword in the I, II, and III periods of the two target areas. The keywords related to the stay type of "rental cottage" and "recreational forest" were derived for Masil Road in relation to accommodation facilities. However, the keywords related to the accommodation were not derived in Gubul Road. Second, as a result of the centrality analysis, the degree centrality of the keywords "walking", "sea", "look", "salt flats" of Masil Road and "walking", "lake" and "park" of Gubul Road was high. The keywords located at the center are "walking" and "sea" in the Masil Road, and "walking" in the Gubul Road. As an influential keyword, Masil Road is "experience" and Gubul Road is "history". Third, According to the results of the analysis, the keywords that appeared at the top of the Gubul Road are derived from the keywords related to the 1 ~ 8 course, and it is judged that the visitors are visiting the 1 ~ 8 course trail evenly. However, the Gubul Road only appears in the top keyword only for a few courses. Through this, it seems that three courses are intensively visited as the main course of 6 Gubul Road, 6-1 Gubul Road, and 8 Gubul Road.

• Fashion & Textile Research Journal
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• 제23권6호
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• pp.744-757
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• 2021

This study aims to develop a bodice and a jacket in 3D of the late 19th to early 20th based on the pattern drafting book of Gordon S. S., which contains body measurement method and pattern drafting system. The findings of this research are as follows. First, female tops of the late 19th to early 20th century are categorized as outer, jacket, vest, and bodice. Of these, this study highlights the jacket, which can be divided into 4 types: 4 kinds of basic jacket, 2 kinds of riding jacket, bolero jacket, and newmarket jacket. Second, by referring to Gordon's pattern drafting system and book, a bodice was developed in 3D format based on the adherence to the following steps: analysis of the pattern drafting system, pattern drafting, 3D virtual simulation, 3D virtual fitting analysis, and the pattern correction. A bodice pattern corrected by 3D virtual clothing simulation results was proposed. Last, a basic sleeve and collar pattern for a basic jacket was drafted, which was followed by the correction and transformation of the bodice pattern. The jacket developed shows great fit except for the issues at the armhole line and shoulder, which were caused by the unique shape of the sleeves(big sleeve head) of the time. The study attempted to develop the past costumes in 3D, providing the basis for interdisciplinary research in the field of fashion history field and suggesting a new approach for the virtual restoration of costumes. Future studies should target to 3D virtual simulation in accordance to the 3D avatar pose in the developed virtual costume.

• Earthquakes and Structures
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• 제23권1호
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• pp.35-57
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• 2022

This article presents a computationally efficient framework for multi-objective seismic design optimization of steel moment-resisting frame (MRF) structures based on the nonlinear dynamic analysis procedure. This framework employs the uniform damage distribution philosophy to minimize the weight (initial cost) of the structure at different levels of damage. The preliminary framework was recently proposed by the authors based on the single excitation and the nonlinear static (pushover) analysis procedure, in which the effects of record-to-record variability as well as higher-order vibration modes were neglected. The present study investigates the reliability of the previous framework by extending the proposed algorithm using the nonlinear dynamic design procedure (optimization under multiple ground motions). Three benchmark structures, including 4-, 8-, and 12-story steel MRFs, representing the behavior of low-, mid-, and high-rise buildings, are utilized to evaluate the proposed framework. The total weight of the structure and the maximum inter-story drift ratio (IDRmax) resulting from the average response of the structure to a set of seven ground motion records are considered as two conflicting objectives for the optimization problem and are simultaneously minimized. The results of this study indicate that the optimization under several ground motions leads to almost similar outcomes in terms of optimization objectives to those are obtained from optimization under pushover analysis. However, investigation of optimal designs under a suite of 22 earthquake records reveals that the damage distribution in buildings designed by the nonlinear dynamic-based procedure is closer to the uniform distribution (desired target during the optimization process) compared to those designed according to the pushover procedure.