• 한국약용작물학회지
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• 제21권3호
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• pp.191-196
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• 2013

The effect on the antioxidant activity and Nitric Oxide activity production inhibitory activity of Taraxacum has not been known. Therefore, phenolics and flavonoid contents were investigated from the ethanol extracts of five different Taraxacum species. The results showed that, among the five Taraxacum, T. hallaisanensis contains the highest total phenolic and flavonoid contents. When the antioxidant activity was measured by DPPH, $ABTS^+$ and reducing power activity, the free radical scavenging activity of T. hallaisanensis was also the highest among five Taraxacum species. However, measurement by CCK-8 assay in Raw264.7 cells indicated that the extracts of Taraxacum species have no effect on cell viability. Moreover, we also investigated the effect of Taraxacum species on NO scavenging activity in lipopolysaccharide (LPS)-stimulated Raw264.7 cells. The results clearly showed that Taraxacum species inhibited NO production, and the inhibitory effect of T. hallaisanensis was the strongest. The above results suggested that Taraxacum species affected the antioxidant and NO scavenging activity, and among the five species, antioxidant and NO scavenging activity assay of T. hallaisanensis was significantly higher than those of other four Taraxacum species. Therefore, T. hallaisanensis could be used as a potential drug with anti-oxidant and anti-inflammatory effect.

• 생약학회지
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• 제25권3호
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• pp.209-213
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• 1994

For the investigation of medicinal resources from Taraxacum species, the studies were carried out to evaluate the pharmaco-constituents in the aerial part of Taroxacum hallaisanensis, an endemic plant of Korea. From BuOH fraction of the MeOH extract, compound 1 (protocatechuic acid, $C_7H_6O_4,\;3,4-dihydroxy\;benzoic\;acid)$, compound 2 $[C_{22}H_{31}O_6,\;luteolin-7-O-{\alpha}-_L-rhamnopyranosyl(1{\rightarrow}6)-{\beta}-_D-glucopyranoside]$, and compound 3 $[C_{15}H_{20}O_6,\;luteolin-7-O-{\beta}-_D-glucopyranoside]$ were isolated by column chromatographic separation using polyamide and ODS-gel. The structures were elucidated by means of physico-chemical evidences($^1H-NMR,\;{12}^C-NMR$, IR, EI-Mass, FAB-Mass and GC).

• Archives of Pharmacal Research
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• 제19권6호
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• pp.507-513
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• 1996

Three sesquiterpene lactone compounds, two novel(1.betha.,3.betha.-dihydroxy-6.betha.,11.betha.,4.alpha.,5.alpha.,7.alpha.H -eudesm-12, 6-olide-1-O-.betha.-D-glucopyranoside, 1.betha.,3.betha.-dihydroxy-6.betha.,11.betha.,4.alpha.,5.alpha.,7.alpha.H-eudes m-12,6-olide-1-O-.betha.-D-glucopyranoside) and 1.betha.,3.betha.-dihydroxy-6.betha.,11.betha.,4.alpha.,5.alpha., 7.alpha.H-eudesm-12,6-olide were isolated from the aqueous fraction of MeOH extract of the roots from Taraxacum hallaisanensis (Compositae) employing Amberlite XAD-2, ODS-gel, silica gel and Sephadex LH-20 column chromatographics. Another known compound, (-)-epicatechin, was isolated from the aqueous fraction of the MeOH extract. The total MeOH extract also contained phytosterol and a mixture of .betha.-amyrin acetate, .alpha.-amyrin acetate and lupeol acetate. Structures of isolated compounds were elucidated by spectroscopic parameters of IR, Mass, /sup 13/C-NMR, /sup 1/H-NMR, /sup 1/H-/sup 1/H COSY, /sup 13/C-/sup 1/H COSY and HMBC.

• 한국자원식물학회지
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• 제21권2호
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• pp.117-127
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• 2008

본 연구는 금원산 생태수목원 조성 부지의 관속식물상을 조사한 후 희귀 및 특산식물, 식물구계학적 특정식물종, 귀화식물 등을 분류함으로써, 생태수목원 조성을 위한 기초자료를 제공하고자 수행한 바 다음과 같은 결론을 도출하였다. 금원산 생태수목원 조성 부지의 관속식물상은 84과 217속 319종 43변종 7품종으로 총 369분류군이 확인되었다. 희귀식물은 구상나무(보존우선순위; 73번)와 산작약(97번)이 확인되었다. 특산식물은 개비자나무, 구상나무(식재), 지리대사초, 떡버들, 키버들, 할미밀망, 은꿩의다리, 털조록싸리, 네잎갈퀴나물, 노각나무, 큰고추나물, 오동(식재), 병꽃나무, 벌개미취(식재) 등 12과 14속 11종 3변종 1교잡종으로 총 15종류가 확인되었다. 식물구계학적 특정식물종은 V등급에 산작약, IV등급에는 확인되지 않았으며, III등급에 구상나무(식재), 중나리, 거제수나무, 물박달나무, 당느릅나무, 참조팝나무, 개벚지나무, 꽝꽝나무(식재), 노각나무, 개회나무, 선백미꽃, 털괴불나무, 병풍쌈 등 13종류, II등급에 처녀치마, 털괭이눈, 복자기, 민둥뫼제비꽃, 곽향등 5종류, I등급에 홍지네고사리, 개비자나무, 전나무(식재), 잣나무(식재), 큰천남성, 흰여로, 퉁둥굴레, 왕버들, 박달나무, 물오리나무, 굴참나무, 투구꽃, 금낭화, 애기괭이눈, 노랑물봉선, 대팻집나무, 피나무, 들메나무, 덩굴꽃마리 등 19종류로 정리되어 총 38종류가 확인되었다. 귀화식물에는 큰조아재비, 큰김의털, 오리새, 호밀풀, 애기수영, 돌소리쟁이, 아까시나무, 족제비싸리, 토끼풀, 달맞이꽃, 개망초, 봄망초, 미국가막사리, 원추천인국, 서양민들레 등 5과 13속 15종류가 확인되었으며, 귀화율은 전체 369종류의 관속식물 중 4.1%로 분석되었다.