• Bulletin of the Korean Chemical Society
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• 제12권2호
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• pp.157-163
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• 1991

The total synthesis of dihydroreynosin (1) and dihydrosantamarine (2) via tandem Cope-Claisen rearrangement has been accomplished starting from (S)-carvone (4).

• Bulletin of the Korean Chemical Society
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• 제33권4호
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• pp.1209-1212
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• 2012

In spite of many reports in the literature concerning with oxidation of benzylic alcohols to carbonyl compounds with 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in stoichiometric amounts or even more, we surprisingly found that benzylic alcohols are directly oxidized to oximes using a catalytic amount of DDQ in the presence of hydroxylamine hydrochloride under solvent-free conditions. The present tandem catalytic method can be efficiently used for preparation of oximes in the presence of some other functional groups with excellent chemoselectivity.

• Bulletin of the Korean Chemical Society
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• 제32권1호
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• pp.315-318
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• 2011

• Bulletin of the Korean Chemical Society
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• 제22권8호
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• pp.857-866
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• 2001

Efficient syntheses of PGI2 analogue 2a and its epimer 3 have been accomplished. Using aryl iodide 6 as the common intermediate, either radical or palladium-assisted tandem alkene insertion strategies have been employed for construction of the benzoprostacyclin framework.

• Bulletin of the Korean Chemical Society
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• 제31권3호
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• pp.670-677
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• 2010

A comparative study on the Au(I)-catalyzed and IBr-promoted tandem cyclization of 1,5-enyne was reported. This study provides a meaningful mechanistic insight to the concerted nature of this tandem reaction and also provides interesting applications in the synthesis of 7/5- or 8/5-fused bicycles and biaryls.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3382-3384
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• 2010

A new synthetic route to ($\pm$)-aspidospermidine was devised, starting from the cycloadduct of 3-ethyl-5-bromo-2-pyrone with vinyl sulfide through a tandem conjugate addition-alkylation sequence. The requisite 3-ethyl-5-bromo-2-pyrone was prepared via the C3-selective Pd-catalyzed coupling reaction with $Et_3Al$-dimethylaminoethanol complex.

• Bulletin of the Korean Chemical Society
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• 제35권7호
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• pp.1970-1972
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• 2014

A facile and efficient synthesis of dronedarone hydrochloride starting from commercially available 4-nitrophenol is described. This approach features a tandem-type synthesis of 3-carbonylated benzofuran involving cyclization of 2-ethynylphenol followed by $CO_2$ fixation at the 3-position of the benzofuran ring mediated by potassium carbonate without the addition of any transition metal catalyst.

• Bulletin of the Korean Chemical Society
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• 제31권3호
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• pp.704-707
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• 2010

• Bulletin of the Korean Chemical Society
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• 제33권12호
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• pp.4271-4274
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• 2012

• 대한기계학회논문집A
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• 제28권4호
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• pp.378-385
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• 2004

Viscous-driven pumping is a very promising type in microscale applications. However, there exist a few disadvantages such as low efficiency and small volume flow rate. In the present study, a pump with tandem rotating cylinders and its optimum synthesis are proposed fur enhancing pumping performance. First, using an unstructured grid CFD method, we investigate the effects of geometrical parameters and then the performance of the pump with tandem cylinders is evaluated. Next, an optimum design synthesis tool is constructed by combining the aforementioned CFD analysis model with the mathematical optimization model, namely, Modified Method of Feasible Directions (MMFD). This technique is used to optimize the geometrical parameters of the pump, fur maximizing pumping efficiency. From the optimization results, it is believed that the present optimum synthesis is robust and has a potential fur other microfluidic device design.