• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2001년도 Bulletin of The 5th Asian Design Conference International Symposium on Design Science
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• pp.50.2-50
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• 2001

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2005년도 학술발표회(2)
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• pp.1096-1097
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• 2005

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.65-69
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• 2002

An Al film deposited on the Kovar alloy substrate was anodically-bonded to the borosilicate glass, and the bond interfaces was closely investigated by transmission electron microscopy. Al oxide was found to form a layer ~l0 nm thick at the bond interface, and fibrous structure of the same oxide was found to grow epitaxially in the glass from the oxide layer. The fibrous structure grew with the bonding time. The mechanism of the formation of this fibrous structure is proposed on the basis of the migration of Al ions under the electric field. Penetration of Al into glass beyond the interfacial Al oxide was not detected. The comparison of the amount of excess oxygen ions generated in the alkali depletion layer with that incorporated in the Al oxide suggests that the growth of the alkali-ion depletion layer is controlled by the consumption of excess oxygen to form the interfacial Al oxide.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.222-224
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• 2002

In proton and heavy ion radiotherapy, compensators are required to modify the energy of heavy ion, to compensate the local difference of tumor depth. Conventional compensators have to be created, exchanged, and stored for each patient and for each irradiation directions. A Cylinder Type Liquid Variable Compensator is and is under development. Hexagonal cylinders will be arranged in honeycomb structure. In which air and fluid are divided by hexagonal pistons. The position of each piston will be changed in each cylinder for adjusting the thickness of fluid for variable compensator. The location of each hexagonal piston is determined by each controlling cylinder connected to the hexagonal cylinder by inlet pipes of fluid. Each controlling cylinder includes controlling a piston, which is moved mechanically. Each controlling cylinder is to be moved by a motor driven by a computer.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.183-185
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• 2002

Heavy ion and proton therapy necessitate range weeks, which are time consuming. Three types of variable compensator, membrane type liquid variable compensator, are proposed by some of the authors to overcome the difficulties, by those arbitrarily thickness distribution of compensator obtained from treatment planning is created at the site of treatment. None of the ideas, however, is yet realized. In this research, we are trying to construct prototype membrane-type liquid variable compensator. This variable compensator partitions air and liquid with elasticity membrane and changes the surface of the elasticity membrane with the thread. The air and oil move through holes to and from the out of beam side of two boxes in which they are contained. The boxes are made of Plexiglas(PMMA), the thread which is made of nylon, the elasticity film which is made from latex for the moment.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.2859-2863
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• 2013

Polyphenolic compounds from pomegranate fruit extracts (PFEs) have been reported to possess antiproliferative, pro-apoptotic, anti-inflammatory and anti-invasion effects in prostate and other cancers. However, the mechanisms responsible for the inhibition of cancer invasion remain to be clarified. In the present study, we investigated anti-invasive effects of ellagic acid (EA) in androgen-independent human (PC-3) and rat (PLS10) prostate cancer cell lines in vitro. The results indicated that non-toxic concentrations of EA significantly inhibited the motility and invasion of cells examined in migration and invasion assays. The EA treatment slightly decreased secretion of matrix metalloproteinase (MMP)-2 but not MMP-9 from both cell lines. We further found that EA significantly reduced proteolytic activity of collagenase/gelatinase secreted from the PLS-10 cell line. Collagenase IV activity was also concentration-dependently inhibited by EA. These results demonstrated that EA has an ability to inhibit invasive potential of prostate cancer cells through action on protease activity.

• 천문학논총
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• 제30권2호
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• pp.679-682
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• 2015

The Hiroshima Astrophysical Science Center (HASC) was founded in 2004 at Hiroshima University, Japan. The main mission of this institute is the observational study of various transient objects including gamma-ray bursts, supernovae, novae, cataclysmic variables, and active galactic nuclei by means of multi-wavelength observations. HASC consists of three divisions; the optical-infrared astronomy division, high-energy astronomy division, and theoretical astronomy division. HASC is operating the 1.5m optical-infrared telescope Kanata, which is dedicated to follow-up and monitoring observations of transient objects. The high-energy division is the key operation center for the Fermi gamma-ray space telescope. HASC and the high-energy astronomy group in the department of physical science at Hiroshima University are closely collaborating with each other to promote multi-wavelength time-domain astronomy. We report the recent activities of HASC and some science topics pursued by this multi-wavelength collaboration.

• 만화애니메이션 연구
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• 통권27호
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• pp.99-125
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• 2012

다양한 만화 장르 중에서 한국의 순정만화와 같은 개념으로 볼 수 있는 '소녀만화'는 일본에서 시작되어 세계 각국으로 전파 된 만화 장르이다. 그리고 소녀만화를 다른 장르와 구분 하는 특징의 하나는 내면의 세계를 그리는 독특한 시각적 표현이다. 본 논문에서는 1950년대 말에서 1960년대 초에 발간된 "소녀", "소녀 클럽", "소녀 북"등의 소녀 잡지에 실린 만화의 시각적 표현, 특히 꽃의 표현과 칸나누기 연출, 속표지의 구성에 초점을 맞추어 분석했다. 그리고 그러한 분석을 통해 이 시기의 작품들이 소녀만화의 기본적인 특징들을 내포하고 있었으며 이러한 시각적 표현은 특히 당시 소수의 여성 작가들에 의해 활발하게 시도되었음을 확인 할 수 있었다. 내면세계와 주인공의 심리를 시각적으로 표현 하는 특징들은 이미 1960년대 초의 소녀만화에서도 드러나 있었다. 소녀만화는 많은 선행 연구자들로부터 1970년대 초반 '황금기'를 맞이하며 그 형식과 표현 방법을 완성 시킨 것으로 평가 받고 있다. 따라서 지금까지의 일본 소녀만화 연구는 소녀만화의 황금기라 불리는 시기에 초점이 맞추어져 있었다. 이 시기에는 다양한 작품이 등장하고 스토리와 시각적 표현에서 완성도가 높아졌다. 그리고 이러한 변화로 독자들의 지지를 받는 인기 작가들이 등장했고, 인기 작가의 등장은 소녀만화 독자층의 확대로 이어졌다는 부분에서 큰 의미를 갖고 있다. 그러나 이들 소녀만화가 갖는 독특한 시각적 표현이 언제부터 등장 했는가에 대한 연구, 즉 초기 소녀 만화 연구는 많이 존재하지 않는다. 이렇듯 1950년대 말에서 1960년대 초의 소녀만화는 1970년대의 소녀만화에 비해 상대적으로 저평가 되고 있다. 본 연구에서는 1958년부터 1963년 사이에 출판된 소녀잡지 만화의 시각적 표현의 특징을 고찰함으로써 소녀만화가 성립되는 과정에 있어 큰 역할을 담당했던 작품과 작가들에 대해 재평가 하고자 한다. 본 연구는 소녀만화의 시각적 표현의 원류가 어디에 있는지 그리고 그러한 특징들이 어떻게 전개되었는가에 대한 새로운 제시가 될 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.391-395
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• 2014

Background: We aimed to evaluate the role of genetic polymorphisms in tobacco carcinogen-metabolizing genes and their interactions with smoking in a hospital-based case-control study of Japanese subjects. Materials and Methods: We examine the associations of pancreatic cancer risk with genetic polymorphisms in GSTM1, GSTT1 and GSTP1, phase II enzymes that catalyze the conjugation of toxic and carcinogenic electrophilic molecules. The study population consisted of 360 patients and 400 control subjects, who were recruited from several medical facilities in Japan. Unconditional logistic regression methods were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between genotypes and pancreatic cancer risk. Results: Among the control subjects, the prevalence of the GSTM1-null genotype and the GSTT1-null genotype was approximately 56% and 48%, respectively. Cases and controls were comparable in terms of GSTM1 and GSTT1 genotype distributions. Neither of the deleted polymorphisms in GSTM1 and GSTT1 was associated with the risk of pancreatic cancer, with an age- and sex-adjusted OR of 0.99 (95%CI: 0.74-1.32) for the GSTM1-null genotype, and 0.98 (95%CI: 0.73-1.31) for the GSTT1-null genotype. The OR was 0.97 (95%CI: 0.64-1.47) for individuals with the GSTM1 and GSTT1-null genotypes compared with those with the GSTM1 and GSTT1- present genotypes. No synergistic effects of smoking or GST genotypes were observed. Conclusions: Our results indicate no overall association between the GSTM1 and GSTT1 deletion polymorphisms and pancreatic cancer risk in the Japanese subjects in our study.