• Aerospace Engineering and Technology
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• v.4 no.1
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• pp.1-8
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• 2005

Civil aviation regulation such as FAR and loads analysis procedure based on this was explained, and loads analysis procedure and results for Smart UAV was presented for application case. For loads analysis, applicable regulations and loads conditions should be prepared in advance, and modeling for aerodynamics, weight, and structure should be performed. Panel method is usually adopted for aircraft loads analysis to obtain aerodynamic loads. In this study, ARGON which is multidisciplinary fixed wing aircraft design software co-developed by KARI and TsAGI was used for loads analysis. ARGON can be utilized for flutter and stress analysis as well as for flight and ground loads analysis. In this paper, flight loads analysis of 4-seater canard airplane was performed with ARGON and that results were presented.

• The Journal of Internal Korean Medicine
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• v.32 no.4
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• pp.599-609
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• 2011

Objectives : The aim of this study was to evaluate the single oral dose toxicity and safety of Bojungikgi-tang (Buzhongyiqi-tang) and fermented Bojungikgi-tang (Buzhongyiqi-tang) extracts in male and female ICR mice. Methods : In the single oral dose toxicity study, non-fermented and fermented Bojungikgi-tang (Buzhongyiqi-tang) were administered to male and female ICR mice as an oral dose of 1250, 2500 and 5000 mg/kg. Changes of body weights, general behaviors, adverse effects and mortality were determined throughout the experimental period. Hematological parameters, serum chemistry, organ weights and necropsy findings were evaluated at the end of the experiment. Results : There was no mortality or sign of toxicity in the single oral dose toxicity study. There were also no significant differences in body weights, organ weights, and hematological parameters, serum chemistry values between treatment and control groups. Conclusions : The results obtained in this study suggest that the 50% lethal dose of fermented Bojungikgi-tang (Buzhongyiqi -tang) in both female and male mice can be considered as well over 5,000 mg/kg, so these medicines can be safe in clinics.

• Genomics & Informatics
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• v.8 no.4
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• pp.194-200
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• 2010

The PIK3CA gene, oncogenic gene located on human chromosome 3q26.3, is an important regulator of cell proliferation, death, motility and invasion. To evaluate the role of PIK3CA gene in the risk of Korean lung cancer, genotypes of the PIK3CA polymorphisms (rs11709323, rs2699895, rs3729679, rs17849074 and rs1356413) were determined in 423 lung cancer patients and 443 normal controls. Statistical analyses revealed that the genotypes and haplotypes in the PIK3CA gene were not significantly associated with the risk of lung cancer in the Korean population, suggesting that these PIK3CA polymorphisms do not contribute to the genetic susceptibility to lung cancer in the Korean population.

• Convergence Security Journal
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• v.3 no.3
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• pp.51-57
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• 2003

The Real-time DBMS must provide the keeping, fabrication and control function which the data where the user requsets for processing inside the hour when it is restricted, it is quick most and safely[3]. In order lide this to take chare of the real-time control and fabrication function, details recording (log) of the control processing is very important in accomplished transactions from inside the Real-time DBMS. In this proposal, it sees recording which is like this in base and it proposes the new recovery function for transactions log. This recovery technique which it sees used the concept of the LIFO (Last-In-First-Out) method with basic. The proposed technique will becomes the technique which it will be able and to record to process efficiently with a same attribute and the continuous transactions log.

• The Journal of Internal Korean Medicine
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• v.32 no.3
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• pp.334-344
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• 2011

Objectives : Sipjeondaebo-tang is a medicine traditionally prescribed as a restorative. The aim of this study was to investigate the single oral dose toxicity and safety of extract of fermented Sipjeondaebo-tang in ICR mice. Methods : In single oral dose toxicity study, non-fermented or fermented Sipjeondaebo-tang were administered by oral gavage to ICR mice (5 males, 5 females) at single doses of varying concentrations: 1250, 2500 and 5000 mg/kg. Changes of body weight, general behavior, adverse effects and mortality were determined throughout the experimental period. Hematological parameters, organ weights and necropsy findings were evaluated at the end of the experiment. Results : There were no mortality or signs of toxicity in single oral dose toxicity studies. There were also no significant differences in body weight, organ weight, or hematological parameters between the treatment and control groups. Conclusions : Fermented Sipjeondaebo-tang did not cause remarkable adverse effects in ICR mice. The oral lethal dose of fermented Sipjeondaebo-tang is more than 5000 mg/kg and no-observed-adverse-effect level (NOAEL) of the extract for both male and female mice is 5000 mg/kg.

• Journal of Yeungnam Medical Science
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• v.13 no.1
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• pp.141-145
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• 1996

Habitual pregnancy loss has been defined as three or more consecutive spontaneous abortions. The rate of recurrent pregnancy loss is 2% to 5% of reproducible women. Half of this failure can be explained by genetic, hormonal, infectious, and anatomic factors. And eighty percent of the unexplained failures are proposed to have an immunologic cause. The antiphospholipid antibodies are characterized by prolonged phospholipid-dependent coagulation test (known as APTT or Russel viper venom), thrombosis, thrombocytopenia, and fetal loss. The association of antiphospholipid antibodies with one or more of these characteristic clinical features has been termed the antiphospholipid syndrome. We have experienced a case of successful live birth after treated a woman with heparin and aspirin who has experienced spontaneous abortion four times with antiphospholipid antibodies and present it with the review of literature.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.116-121
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• 2011

Performance of Secondary Injection Thrust Vector Control system is investigated under various secondary injection operating conditions. 3-dimensional converging-diverging nozzle having 8 secondary injection nozzles is used in this numerical study. Total pressure of flow inside the nozzle is about 70bars, and total temperature set to 300K for cold flow simulation. Effect of secondary injection flow rate and injection nozzle configuration is considered in this research. Simulation is conducted with commercial CFD code Ansys Fluent v13. Spalart-Allmaras(1-equation)model is used for turbulence modeling with AUSM+ scheme. Various performance factors as Axial thrust, side force, system specific impulse ratio are considered and explained for system performance evaluation.

• Journal of the Korea Institute of Military Science and Technology
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• v.9 no.4
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• pp.15-23
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• 2006

In this paper, full-scale airframe static test of 4-seater canard airplane(the Firefly) was explained. From the results of the structural analysis, 5 design limit loads test conditions and 11 design ultimate loads test conditions were selected. Test loads analysis was performed and test fixtures and load control system(LCS) were prepared to realize the test loads. To protect the test article during the test, the overload protection system was prepared. Strain and deflection values were acquired through the data acquisition system(DAS) to verify the structural analysis results.

• Journal of Haehwa Medicine
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• v.11 no.1
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• pp.257-283
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• 2002

Objectives : Sipjundaebo-tang is prepared by ten medical herbs that tone the blood and vital energy, and strengthen health. This prescription has long been used traditionally against anemia, anorexia, extreme exhausion and fatigue. The purpose of this thesis was to review the effects of Sipjundaebo-tang that are about immunopotentiation effects, antitumor activities and potentiation, detoxification of antitumor drugs Methods : We studied the research methods and results of experiments which were selected from Korean, Japaness and American theses were on the topic of immunopotentiation effects, antitumor activities and potentiation, detoxification of antitumor drugs from Sipjundaebo-tang Results and conclusions : Sipjundaebo-tang not only potentiates the effects of the combined use of chemotherapy, but also reduces and elimimate the immunotoxicity of antitumor drugs and radiotherapy. And it strengthen immunity and improve QOL, S/OH of cancer patients.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.815-820
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• 2009

Binary nanoemulsions which are defined as the, oil-droplet suspensions in binary solution ($H_2O$/LiBr), are developed to enhance the heat and mass transfer performance of absorption refrigeration systems. In this study, a novel two-step method is proposed to prepare the stable oil-in-binary solution (O/S) emulsion. Polymer is used as a steric stabilizer to stabilize the oil-droplets in a strong electrolyte ($H_2O$/LiBr). It is found that the thermal conductivity of the binary nanoemulsion is inversely proportional to the emulsion size while the concentrations of oil and $H_2O$/LiBr are less dominant for the thermal conductivity of binary nanoemulsions.