• Journal of the Computational Structural Engineering Institute of Korea
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• v.31 no.4
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• pp.183-190
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• 2018

This paper presents optimization of the main spar of Human-Powered Aircraft (HPA) wing. Mass minimization was attempted, while considering large torsional deformation of the beam. Sequential Quadratic Programming (SQP) method was adopted as a relevant tool to conduct structural optimization algorithm. An inner diameter and ply thicknesses of the main spar were selected as the design variables. The objective function includes factors such as mass minimization, constant tip bending displacement, and constant tip twist of the beam. For estimation of bending and torsional deformation, the geometrically exact beam model, which is appropriate for large deflection, was adopted. Properties of the cross sectional area which the geometrically exact beam model requires were obtained by Variational Asymptotic Beam Sectional Analysis (VABS), which is a cross sectional analysis program. As a result, maintaining tip bending displacement and tip twist within 1.45%, optimal design that accomplished 7.88% of the mass reduction was acquired. By the stress and strain recovery, structural integrity of the optimal design and validity of the present optimization procedure were authenticated.

• Journal of Korean Neurosurgical Society
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• v.59 no.3
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• pp.187-191
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• 2016

Craniosynostosis is defined as the premature fusion of one or more of the cranial sutures. It leads not only to secondary distortion of skull shape but to various complications including neurologic, ophthalmic and respiratory dysfunction. Craniosynostosis is very heterogeneous in terms of its causes, presentation, and management. Both environmental factors and genetic factors are associated with development of craniosynostosis. Nonsyndromic craniosynostosis accounts for more than 70% of all cases. Syndromic craniosynostosis with a certain genetic cause is more likely to involve multiple sutures or bilateral coronal sutures. FGFR2, FGFR3, FGFR1, TWIST1 and EFNB1 genes are major causative genes of genetic syndromes associated with craniosynostosis. Although most of syndromic craniosynostosis show autosomal dominant inheritance, approximately half of patients are de novo cases. Apert syndrome, Pfeiffer syndrome, Crouzon syndrome, and Antley-Bixler syndrome are related to mutations in FGFR family (especially in FGFR2), and mutations in FGFRs can be overlapped between different syndromes. Saethre-Chotzen syndrome, Muenke syndrome, and craniofrontonasal syndrome are representative disorders showing isolated coronal suture involvement. Compared to the other types of craniosynostosis, single gene mutations can be more frequently detected, in one-third of coronal synostosis patients. Molecular diagnosis can be helpful to provide adequate genetic counseling and guidance for patients with syndromic craniosynostosis.

• Corrosion Science and Technology
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• v.10 no.1
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• pp.1-5
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• 2011

The major purpose of the present study is to evaluate the performance of various galvanized (GI) or galvannealed (GA) mild steels and AHSS in stamping applications. Finite Element Analysis (FEA) of selected stamping operations was conducted to estimate the critical pressure boundary conditions that exist in practice. Using this information, laboratory tribotests, e.g. Twist Compression (TCT), Deep Drawing (DDT) and Strip Drawing (SDT) Tests, were developed to evaluate the performance of selected lubricants and die materials/coatings in forming galvanized steels of interest. The sheet materials investigated included mild steels and AHSS (e.g. DP600 GI/GA, DP780 GI/GA, TRIP780 GA and DP980 GI/GA). Experimental results showed that galvanized material resulted in more galling, while galvannealed material showed more powdering and flaking. The surface roughness and chemical composition of galvanized sheet materials affected the severity of galling under the same testing conditions, i.e. lubricants and die materials/coatings. The results of this study helped to determine the critical interface pressure that initiates lubricant failure and galling in stamping selected galvanized sheet materials. Thus, to prevent or postpone the critical interface conditions, the results of this study can be used to select the optimum combination of galvanized sheet, die material, die coating and lubricant for forming structural automotive components.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.86.1-86.1
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• 2012

The MHD virial theorem applied for observed photospheric field may be the one of way to estimate magnetic energy of generally invisible coronal magnetic structure. However, the photospheric field is not in a force-free state, so the application of virial theory needs some care. Here we use a series of MHD simulations of emerging field to investigate how we can apply the virial theorem to the emerging field. In early emerging phase, virial energy has a minus value although positive area at the photosphere is continuously generated toward a late emerging phase. We discuss why this tendency occurs. Then we derive the critical height where the actual emerging magnetic energy is almost comparable to the virial energy. If the difference between virial energy and magnetic energy becomes 10 percentage of the magnetic energy, we define this is the critical height, and assume the emerging field is close to force-free. We also discuss how the critical height changes with the initial twist of an emerging flux tube.

• Journal of Aerospace System Engineering
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• v.2 no.1
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• pp.7-12
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• 2008

The three-dimensional finite element modeling of a composite rotor blade is very hard and requires much computation effort. The efficient method to model a composite beam is necessary for the dynamic and aeroelastic analyses of rotor blades. In this study, the beam modeling method of a composite rotor blade is studied using VABS. The computer program, VABS (Variational Asymptotic Beam Section Analysis), uses the variational asymptotic method to split a 3-D nonlinear elasticity problem into 2-D cross-sectional analysis and 1-D nonlinear beam problem. The VABS can produce the sectional stiffness coefficients of composite rotor blades with various cross section and initial twist/curvatures, and recover the original 3-D distribution of displacement/strain/stress fields. The results of various cross section beams show that VABS gives us the accurate results comparared to commercial codes and does not need much computation effort. It can be concluded that VABS provides the efficient method to establish the FE model of a composite rotor blade.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.69.1-69.1
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• 2014

We perform an MHD simulation combined with observed vector field data to clarify an eruptive dynamics in the solar flare. We first extrapolate a 3D coronal magnetic field under a Nonlinear Force-Free Field (NLFFF) approximation based on the vector field, and then we perform an MHD simulation where the NLFFF prior to the flare is set as an initial condition. Vector field was obtained by the Soar Dynamics Observatory (SDO) at 00:00 UT on February 15, which is about 90 minutes before the X2.2-class flare. As a result, the MHD simulation successfully shows an eruption of strongly twisted lines whose values are over one-turn twist, which are produced through the tether-cut magnetic reconnection in strongly twisted lines of the NLFFF. Eventually, we found that they exceed a critical height at which the flux tube becomes unstable to the torus instability determining the condition that whether a flux tube might escape from the overlying field lines or not. In addition to these, we found that the distribution of the observed two-ribbon flares is similar to the spatial variance of the footpoints caused by the reconnection of the twisted lines being resided above the polarity inversion line. Furthermore, because the post flare loops obtained from MHD simulation well capture that in EUV image taken by SDO, these results support the reliability of our simulation.

• Interaction and multiscale mechanics
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• v.1 no.2
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• pp.231-250
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• 2008

The statistical two-order and two-scale method is developed for predicting the mechanics parameters, such as stiffness and strength of core-shell particle-filled polymer composites. The representation and simulation on meso-configuration of random particle-filled polymers are stated. And the major statistical two-order and two-scale analysis formulation is briefly given. The two-order and two-scale expressions for the strains and stresses of conventionally strength experimental components, including the tensional or compressive column, the twist bar and the bending beam, are developed by means of their classical solutions with orthogonal-anisotropic coefficients. Then a new effective mesh generation algorithm is presented. The mechanics parameters of core-shell particle-filled polymer composites, including the expected stiffness parameters, minimum stiffness parameters, and the expected elasticity limit strength and the minimum elasticity limit strength, are defined by means of the stiffness coefficients and elasticity strength criterions for core, shell and matrix. Finally, the numerical results for predicting both stiffness and elasticity limit strength parameters are compared with the experimental data.

• BMB Reports
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• v.48 no.3
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• pp.127-128
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• 2015

Tumor metastasis involves circulating and tumor-initiating capacities of metastatic cancer cells. Hepatic TM4SF5 promotes EMT for malignant growth and migration. Hepatocellular carcinoma (HCC) biomarkers remain unexplored for metastatic potential throughout metastasis. Here, novel TM4SF5/CD44 interaction-mediated self-renewal and circulating tumor cell (CTC) capacities were mechanistically explored. TM4SF5-dependent sphere growth was correlated with $CD133^+$, $CD24^-$, ALDH activity, and a physical association between CD44 and TM4SF5. The TM4SF5/CD44 interaction activated c-Src/STAT3/ Twist1/ B mi1 signaling for spheroid formation, while disturbing the interaction, expression, or activity of any component in this signaling pathway inhibited spheroid formation. In serial xenografts of less than 5,000 cells/injection, TM4SF5-positive tumors exhibited locally-increased CD44 expression, suggesting tumor cell differentiation. TM4SF5-positive cells were identified circulating in blood 4 to 6 weeks after orthotopic liver-injection. Anti-TM4SF reagents blocked their metastasis to distal intestinal organs. Altogether, our results provide evidence that TM4SF5 promotes self-renewal and CTC properties supported by $CD133^+/TM4SF5^+/CD44^+^{(TM4SF5-bound)}/ALDH^+/CD24^-$ markers during HCC metastasis.

• Journal of the Korea Furniture Society
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• v.26 no.1
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• pp.22-30
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• 2015

In order to prevent decay, distortion, bending, twist on wood products such as wooden furnitures, variety of coating materials were developed and used so far. The coating materials for wood finishing can be synthesized by natural resource or petroleum. However, these coating materials can cause contamination of indoor air quality due to emission of volatile organic compounds (VOCs). In this study, commercialized coating materials for wood finishing such as varnish, coat, and stain were evaluated on emission characteristics of VOCs. Among the varnish, eco-friendly products had about 15~46% lower TVOC emission ($1,042{\mu}g/m^2h{\sim}3,257{\mu}g/m^2h$, respectively, than typical product ($7,100{\mu}g/m^2h$). Natural resource based coating material showed lowest TVOC emission level. However, one of natural resource based waterborne stain showed higher TVOC emission level because waterborne stain already contained higher amount of natural VOC. Oil-based stain might not be suitable for indoor use on interior wall and furniture due to exceed amount of TVOC. Based on results, natural resource based coat or waterborne stain are recommenced to use on wood products.

• Journal of the Korean Society for Precision Engineering
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• v.2 no.2
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• pp.43-59
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• 1985

In relation to the machinability of drilling operation, experiments were made to investigate the effect of cutting condition on static as well as dynamic cutting resistances in cutting plane carbon steel (SM 45 C) with H.S.S. twist drills. The results were as follows. 1) The static cutting resistances on carbon steel can practically be calculated by the following equations which were derived from experimental result. The deviation from the experimental values was less than 8% and 13% for cutting torque and thrust respectively. For cutting torque M: M=0.019 $H_B\;{f^{0.68}d^{1.68}$ For thrust T: T=0.400406 $r^{0.6}d^{0.68}$ + 0.1835 $H_BC^2$(where $H_B$: Brinnel hardness) 2) The static components of cutting resistance are increased exponentially with increasing drill diameter and feed rate. On the effect of drill diameter, the dynamic components of torque are decreased with increasing dirll diameter because of rigidity, the dynamic components of thrust being not effected with the changes. 3) As feed rates increase, the dynamic components of torque rather decrease although its changes on thrust components are unstable. 4) The static components of cutting resistance and dynamic component of torque are slightly decreased in accordance with the increase of spindle speed although its dynamic thrust components are not effected by the spindle speed.