• Journal of dental hygiene science
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• v.18 no.3
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• pp.188-193
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• 2018

The aim of the current study was to demonstrate the potential therapeutic efficacy of resveratrol in oral cancer patients. Lysophosphatidic acid (LPA) intensifies cancer cell invasion and metastasis, whereas resveratrol, a natural polyphenolic compound, possesses antitumor activity, suppressing cell proliferation and progression in various cancer cell lines (ovarian, gastric, oral, pancreatic, colon, and prostate cancer cells). In addition, resveratrol has been identified as an inhibitor of LPA-induced proteolytic enzyme expression and ovarian cancer invasion. Furthermore, resveratrol was shown to inhibit oral cancer cell invasion by downregulating hypoxia-inducible factor $1{\alpha}$ and vascular endothelial growth factor expression. Recently, we demonstrated that LPA is important for the expression of transcription factors TWIST and SLUG during epithelial-mesenchymal transition (EMT) in oral squamous carcinoma cells. In this study, we treated serum-starved cultures of oral squamous carcinoma cell line YD-10B with resveratrol for 24 hours prior to stimulation with LPA. To identify an optimal resveratrol concentration that does not induce apoptosis in oral squamous carcinoma cells, we determined the toxicity of resveratrol in YD-10B cells by assessing their viability using the MTT assay. Another assay was performed using Matrigel-coated cell culture inserts to detect oral cancer cell invasion activity. Immunoblotting was applied for analyzing protein expression of SLUG, TWIST1, E-cadherin, and GAPDH. We demonstrated that resveratrol efficiently inhibited LPA-induced oral cancer cell EMT and invasion by downregulating SLUG and TWIST1 expression. Therefore, resveratrol may potentially reduce oral squamous carcinoma cell invasion and metastasis in oral cancer patients, improving their survival outcomes. In summary, we identified new targets for the development of therapies against oral cancer progression and characterized the therapeutic potential of resveratrol for the treatment of oral cancer patients.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2001.10a
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• pp.225-230
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• 2001

Small diameter drilling which take high precision in cutting work is needed more small hole and high speed working. Especially, small hole deep drilling is one of the most important machining types and its necessity and importance become more and more increasing in the whole field of industry. This paper shows the limit depths with small diameter drills using experimental analysis. The results are gained by tool dynamometer and Labview system and obtained during small diameter twist drilling system on SM45C steel for different machining conditions. The machine and tools are the CNC machining center and twist drill of diameter 1.5mm. And additionally, tool microscope show the relationship between shapes of chips and breakage shapes of small diameter drills.

• Korean Journal of Applied Biomechanics
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• v.16 no.4
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• pp.165-173
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• 2006

The purpose of this study was to analyze Yurchenko's 900 degree twist technique between the highly scored and the lowly scored subjects during the 2003 TaeGu Universiad Championship. The following results was obtained by analyzing horizontal, vertical and resultant velocities on 1st, 2nd, 3rd and 4th phases. The highly scored subject took longer total performance time but shorter time in 2nd and 300 phases. The highly scored subject also took longer performance time in 4th phase. In the board contact phase the highly scored subject had bigger elbow joint angle and shoulder joint angle. The highly scored subject had longer flying time and had more higher vertical height but lower horizontal and resultant velocities on 4th phase.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11a
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• pp.380.1-380
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• 2002

Vibration analysis of rotating blade is the main purpose of present study. In this work, general formulation is proposed to analyze rotating shell type structures including the centrifugal force, Coriolis acceleration and initial twist. Futhermore, simplified equations are derived for the case of an open circular cylindrical shell. Based on the concept of degenerated shell element with the Reissner-Mindlin's assumptions, the finite element method is adopted for solving the governing equations. (onitted)

• Journal of the Korean Vacuum Society
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• v.12 no.S1
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• pp.33-35
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• 2003

The electrooptic properties of the reflected light in a reflective mode, $45^{\circ}C$twisted nematic liquid crystal (TNLC) cell were investigated in the voltage regions near and away from the Freedericksz transition threshold. The measured reflectivity away from the threshold voltage ($V_th$) could not be described by the model which assurnes a constant tilt angle as well as a linearized distribution of twist angle across the cell, although the data are well fitted near $V_th$. We found that in the voltage region away from $V_th$, the model considering the distributions of the tilt angle and the twist angle should be applied for the calculation of the reflectivity. The director-axis distributions were obtained from the numerical integration of the Euler-Lagrange equation.

• Textile Coloration and Finishing
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• v.13 no.1
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• pp.68-75
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• 2001

Tensile and shrinkage characteristics of DTY, EDY and Macel were investigated experimentally. The drawn textured yarn(DTY) made by an existing belt type false twist and the elastic drawn textured yarn(EDY) made by non-torque false twist method modified from the belt type one. Macel was the yarn which had drawn and un-drawn arrangements. The tenacity of EDY had lower value than that of DTY. EDY had higher strethch than that of DTY. Especially Macel yarn had higher stretch than that of DTY compared with the same diameter of yarn. With time course behavior the tenacity and elongation of DTY and EDY had stabled tendency without variation. Before scouring Process, the wet and dry shrinkage patio of EDY load higher value than that of DTY. However, they decreased artier the process. At the same time, the stretch characteristic of EDY was significant as the diameter of yarn became higher.

• Journal of the Chungcheong Mathematical Society
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• v.14 no.1
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• pp.85-103
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• 2001

Suppose that Hand K are paired Hopf algebras and that A is an H - K - bicomodule algebra with multiplication which is a left H-comodule map and is a right K-comodule map. We define a new twisted algebra, $A^{\tau}$ and define $M^{\tau}$ for $M{\in}M_A^K$. We find an equivalent condition for $M^{\tau}{\in}M_{A^{\tau}}^K$. We show that the above defined twisted multiplication is the special case of Beattie's twist multiplication. We show that if K is commutative, then A is an H-module algebra and show that if $H^*$ is cocommutative then the construction of smash product appears as a special case of the new twist product.

• Communications of the Korean Mathematical Society
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• v.33 no.1
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• pp.325-335
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• 2018

We prove every oriented compact cyclic 3-orbifold has a contact structure. There is another proof in the web by Daniel Herr in his uploaded thesis which depends on open book decompositions, ours is independent of that. We define overtwisted contact structures, tight contact structures and Lutz twist on oriented compact cyclic 3-orbifolds. We show that every contact structure in an oriented compact cyclic 3-orbifold contactified by our method is homotopic to an overtwisted structure with the overtwisted disc intersecting the singular locus of the orbifolds. In course of proving the above results we prove a classification result for compact oriented cyclic-3 orbifolds which has not been seen by us in literature before.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.1
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• pp.87-95
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• 2012

In recent years, laser-arc hybrid welding has begun to be adopted for assembly welding of automotive bodies and parts, because the hybrid welding process can weld lapped steel sheets having a larger gap than is possible with laser welding. In this paper, to predict the twist deformation by the hybrid welding when brackets are welded in B pillar of a passenger car, the residual stress using CAE is analyzed and the deformation result of CAE is compared with the measured deformation. First of all, after modeling heat source as intended to be expressed with laser-arc hybrid welding method, heat source fitting is done with welding conditions and a section of welding part obtained through specimen test. In case of heat source functions, laser used conical source and arc used double ellipsoid source. Through the local model analysis, elements which are located in the center of the model are selected. The elements are called WME(Welding Macro Element). This WME is extruded in the welding lines and welding phenomenon of complex parts is accomplished. The deformation amount after hybrid welding is got through a simulation, the validity of simulation is verified by measuring the panel and comparing with the simulation result.

• Journal of the Korean Society of Clothing and Textiles
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• v.30 no.2 s.150
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• pp.255-265
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• 2006

The purpose of this study was to examine the dyeing properties of four kinds of composite yams that were twisted in different processes. The composite yarns consist of acetate and functional polyester in ratio of 70 : 30. The composite yams were dyed at 100$^{circ}C$ and 125$^{circ}C$ using three types of dyes, disperse dyes for acetate fiber, PET fiber and PET-acetate blended fiber, in the three primary colors. The exhaustion($\%$) and K/S value were observed for each case. Also the effects of four different twisting processes to dyeing properties and physical properties were examined. Regardless of twisting methods, the composite yarns that were dyed at 125$^{circ}C$ had higher exhaustion($\%$) than those were dyed at 100$^{circ}C$ with all three types of dyes; However, tendency of the K/S value after reduction cleaning process was measured at 100$^{circ}C$ and the value measured 125$^{circ}C$ had a great difference with disperse dyes for acetate and dyes for PET. The difference of the K/S values of composite yarns, when dyed at 100$^{circ}C$ and 125$^{circ}C$ with disperse dyes for PET-acetate blended fiber, was almost negligible. According to twisting methods K/S values were in the following order: AP1 > AP3 > AP4> AP2. This means that AP1, treated at 220$^{circ}C$, had the highest K/S value and K/S value becomes higher as the yam is higher twisted and becomes lower as lower twisted. On the other hand, the dry shrinkage and wet shrinkage showed low shrinkage rate when the twist was high and steam setting temperature was high.