• Proceedings of the Korea Information Processing Society Conference
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• 2006.05a
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• pp.501-504
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• 2006

본 논문에서는 텍스트로 구성된 문서에 대한 음성 변환 시스템의 각 분야에 대해 기술하고, 음성합성 기술인 TTS기반의 음성지원 일정관리 시스템 설계 및 구현 부분에 대하여 설계한다. 이를 위해서 음성합성 기술의 개념 및 원리와 구조 등을 이해하고, 시스템 설계 및 구현을 하고자 한다. 시스템 설계 구현부에는 Speech SDK 5.1(음성합성엔진)을 사용하여 음성합성 기술부분을 처리하고, 이를 바탕으로 C# 언어를 사용하여 구현한다. 기존 텍스트기반의 일정관리 시스템 설계 부분에다가 음성합성 기능을 추가하여 텍스트의 지루함을 탈피하고, 음성 기술을 접목시켰다. 본 논문에 사용되는 엔진은 영문위주의 음성합성이므로 시스템 설계 부분에 있어 음성처리 부분을 영문으로 하여 결과물을 산출하였다. 최종적으로 실험에 의해 제안한 방법의 유용성을 입증한다.

• Biomolecules & Therapeutics
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• v.5 no.3
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• pp.260-264
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• 1997

The bioequivalence of two nicotine patches was evaluated in 16 normal male volunteers (age 21 ~ 27 yrs) following single transdermal application. Test product was "Nicostop patch" made by Sam Yang Co. and reference product was "Nicotinell TTS patch" made by Korean Searle Ciba-Geigy Co. After nicotine patches were applied onto the inside of the forearm, blood was taken at predetermined time intervals and the nicotine concentration in plasma was determined with a sensitive GC method using NPD detector. AUC and Cm\ulcorner were calculated and statistically analyzed for the bioequivalence of the two products. The results showed that the differences in AUC and $C_{msx}$between two products were 5.47% and 2.70%, respectively. The powers (1-$\beta$) for AUC and $C_{max}$. were >90% and 88.76%, respectively. Detectable differences($\Delta$) and confidence intervals were all less than 20%. All of these parameters met the criteria of KFDA for bioequivalence, indicating that "Nicostop patch" is bioequivalent to "Nicotinell TTS patch" . . .

• Journal of Ginseng Research
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• v.34 no.4
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• pp.336-341
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• 2010

One mechanism of inner ear damage by noise-induced hearing loss (NIHL) is the production of reactive oxygen species (ROS). Because Korean red ginseng (KRG) has an anti-ROS effect in various tissues, KRG may have a role in preventing NIHL. A window period exists in which ROS formations continue after noise exposure, and further damage can be prevented by antioxidants. In this study, we aimed to investigate the effects of KRG after exposure to noise. KRG (200 mg/kg) was fed to mice for 3 days after noise exposure. The change in hearing level was analyzed by measuring the auditory brainstem response. To induce a temporary threshold shift (TTS) of hearing, mice were exposed to 110 dB white noise for 3 hours. Fast recovery of hearing was observed in mice fed KRG 1 hour and 1 day after noise exposure for 3 days. The expression of 8-oxoguanine was not observed in the inner ears of mice fed KRG 1 hour after noise exposure, but was evident in the stria vascularis of mice in the control group (noise exposure only). From this study, we conclude that KRG acted as an effective inhibitor of NIHL in TTS cases.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.05a
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• pp.879-881
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• 2010

For the rapid development of society, such as small family, one-people family is following. The traditional family is being changed, so the older stay home alone. That makes it more and more. Staying home alone, the older's health and safety are worth considering by us. With the rapid development of RFIDRadio Frequency Identification) technology, its applications have extended to all areas of our lifes. RFIDRadio Frequency Identification) has became a major topic of concern in multi-industry. With the high-speed economic growth and the development of science, medicine, the old people's life expectancy is increasing slightly. So it is necessary to design a protective system for the older's safety. In this thesis, self-care system is made by using RFID(Radio Frequency Identification) technology to authenticate an user and using TTS(test to speech) to convert character information to voice information and also using infrared radiation technology to protect home effectively, and using e-blood pressure monitors to examination the older's bodies.

• Food Science and Biotechnology
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• v.17 no.1
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• pp.90-94
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• 2008

Dynamic rheological properties of honey samples with 3 different moisture contents (17.2, 19.0, and 21.0%) were evaluated at various low temperatures (-15, -10, -5, and $0^{\circ}C$) using a controlled stress rheometer. The honey samples displayed a liquid-like behavior, with loss modulus (G") predominating over storage modulus (G') (G">>G'), showing the high dependence on frequency ($\omega$). The magnitudes of G' and G" decreased with an increase in temperature and water content while a predominant increase of G' was noticed at $-15^{\circ}C$. The time-temperature superposition (TTS) principle was applied to bring G" values for honeys at various temperatures together into a master curve. The G" over the temperature range of -15 to $0^{\circ}C$ obeyed the Arrhenius relationship with a high determination coefficient ($R^2=0.98-0.99$). Activation energy value (Ea=112.4 kJ/mol) of honey with a moisture content of 17.2% was higher than those (Ea=98.8-101.1 kJ/mol) of other honey samples with higher moisture contents.

• Journal of the Korean Applied Science and Technology
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• v.17 no.1
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• pp.43-48
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• 2000

Drug delivery system(DDS) applied to various fields, such as medicine, cosmetics, agriculture and necessities of life. Among these application fields, DDS is often used as the method of drug dosage into the epidermic skin. We investigated characters of transdermal therapeutic system(TTS) and the skin permeability of that with applying DDS. Chitosan was selected as material of TTS. We investigated the permeation of chitosan ointment containing drug in rat skin using horizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug such as riboflavin in vitro. We used glycerin, PEG 600 and oleic acid as enhancers. Since dermis has more content water(hydration) than the stratum corneum, skin permeation rate at steady state was highly influenced when glycerin was used in water-soluble drug. The permeation rate of content enhancer and drug was found to be faster than that of content water-soluble drug only. These results showed that skin permeation rate of drug across the composite was manly dependent on the property of ointment base and drug. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate.

• Neonatal Medicine
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• v.15 no.1
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• pp.67-74
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• 2008

Purpose : The purpose of this study was to assess the natural history and perinatal outcomes of twin gestations according to chorionicity. Methods : We retrospectively reviewed the medical records of 99 monochorionic (MC) and 206 dichorionic (DC) twin gestations delivered at Il Sin Christian Hospital in Busan between January 2002 and December 2007. The incidences of twin-to-twin transfusion syndrome (TTS) and selective intrauterine growth restriction (sIUGR), as well as perinatal morbidity and mortality, were evaluated. Results : MC twins had a lower gestational age (35.7 vs. 36.6 weeks, P=0.03) at birth and a higher incidence of intrauterine fetal loss (10% vs. 1.5%, P<0.001) than DC twins. The incidence of intrauterine fetal loss was higher in MC sIUGR than in DC sIUGR (19% vs. 2.5%, P=0.025) twins. The number of admissions to the neonatal intensive care unit (NICU; 31% vs. 16%, P=0.042), and the incidence of periventricular leukomalacia (7% vs. 0%, P=0.031), and respiratory distress syndrome with surfactant treatment (27% vs. 11%, P=0.049) were higher in MC than DC twins. The incidences of sIUGR and TTS were 21 and 9% among the MC twins. The incidences of intrauterine fetal loss were higher in MC twins with TTS [6 of 9 (67%)] or sIUGR [4 of 21 (19%)] than uncomplicated MC twins (P<0.001). The frequency of admission to the NICU (P=0.001), the length of hospital stay (P=0.033), the prevalence of periventricular leukomalacia (P=0.011), and intraventricular hemorrhage (P=0.007) were also higher in MC with TTS or sIUGR than in uncomplicated MC twins. Conclusion : The incidence of neonatal complications was higher in MC twins, especially those gestations complicated by TTS or sIUGR.

• The Journal of the Korea Contents Association
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• v.12 no.1
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• pp.38-47
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• 2012

In order to extend the activity range of visually impaired persons, we design and implement a navigation system that supports road information services and points of interest. The proposed navigation system consists of route creation modules and storage modules for visually impaired persons. In particular, the main interface of the navigation system are implemented using TTS(Text-to-Speech) program for sound and braille module that outputs braille with sense of touch. We also use google map APIs that can provide latest map information for the navigation system.

• Language and Information
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• v.8 no.1
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• pp.117-136
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• 2004

In this paper, we have proposed Auto- TSS, an automatic transcription module of three ambiguous symbols-period (．), colon (:) and slash (／)--using their linguistic contexts. Few previous studies have discussed the problems of ambiguities in reading those symbols into Korean alphabetic letters in order to improve the current Korean TTS (Text-To-Speech) systems. We have classified 9 different reading formulae of the three symbols, analyzed their left and right contexts, and investigated selection rules and distributions between the symbols and their contexts. Based on these linguistic features, 30 stereotyped patterns, 53 rules and 5 heuristics determining the types of reading formulae are investigated for Auto-TSS. This module works modularly in 4 steps. The pilot test was conducted with three test suites, which contain respectively 6,979, 3,491 and 2,450 morpheme clusters containing at least one of three ambiguous symbols and Arabic numeral(s). Encouraging results of 94.3%, 93.0%, 94.2% accuracy were obtained for the test suites. Our next phases are to develop a guessing routine for unknown contexts of the union symbols by using statistical information; to refine the proper nouns and terminology detecting module; and to apply Auto-TSS on a larger scale.

• Journal of Korean Foot and Ankle Society
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• v.17 no.1
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• pp.74-77
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• 2013

Tarsal tunnel syndrome (TTS) is an entrapment neuropathy of the posterior tibial nerve or one of its branches within the tarsal tunnel, and is often caused by ganglia, lipoma, accessory muscles, varicosities, neural tumours, trauma and systemic diseases. We have successfully treated a patient with tarsal tunnel syndrome which was associated with os sustentaculi.