• Journal of Korean Neurosurgical Society
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• 제41권6호
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• pp.397-402
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• 2007

Objective : Balloon cells and dysplastic neurons are histopathological hallmarks of the cortical tubers of tuberous sclerosis complex [TSC] and focal cortical dysplasia [FCD] of the Taylor type. They are believed to be the epileptogenic substrate and cause therapeutic drug resistant epilepsy in man. P-glycoprotein [P-gp] is the product of multidrug resistance gene [MDR1], and it maintains intracellular drug concentration at a relatively low level. The authors investigated expression of P-gp in balloon cells and dysplastic neurons of cortical tubers in patients with TSC. Methods : An immunohistochemical study using the primary antibody for P-gp, as an indicative of drug resistance, was performed in the cortical tuber tissues in two patients of surgical resection for epilepsy and six autopsy cases. Results : Balloon cells of each lesion showed different intensity and number in P-gp immunopositivity. P-gp immunopositivity in balloon cells were 28.2%, and dysplastic neurons were 22.7%. These immunoreactivities were more prominent in balloon cells distributed in the subpial region than deeper region of the cortical tubers. Capillary endothelial cells within the cortical tubers also showed P-gp immunopositivity. Conclusion : In this study, the drug resistance protein P-glycoprotein in balloon cells and dysplastic neurons might explain medically refractory epilepsy in TSC.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1997년도 춘계학술대회 논문집
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• pp.273-276
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• 1997

This paper describes the thermally stimulated current (TSC) measurements of arachidic acid and polyamic acid alkylamine salt(PAAS) LB film, which is a precursor of polyimide(PI). The measurements were performed from room temperature to about 25$0^{\circ}C$ and the temperature was increased at a rate of 0.02 K/s linearly. It shows that peaks of TSC are observed at about 8$0^{\circ}C$ in the arachidic acid and about 8$0^{\circ}C$, 16$0^{\circ}C$ in the PAAS LB films. Results of these measurements indicate that one peak at 8$0^{\circ}C$ is resulted from alkyl group; the other peak at 16$0^{\circ}C$ is due to alkyl and C-O group of PAAS. Additional large peak at about 16$0^{\circ}C$ is due to dipole moments in the PAAS films. The DSC of PAAS, arachidic acid and octadesylamine are measured. Thermal imidization was performed at 30$0^{\circ}C$ for 1 hour by our pre study.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1996년도 추계학술대회 논문집
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• pp.199-202
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• 1996

This paper describes the thermally stimulated current (TSC) measurements of arachidic acid and polyamic acid alkylamine salt(PAAS) LB film, which is a precursor of polyimide(PI). The measurements were performed from room temperature to about 25$0^{\circ}C$ and the temperature was increased at a rate of 0.02 K/s linearly. It shows that peaks of TSC are observed at about 8$0^{\circ}C$ in the arachidic acid and about 8$0^{\circ}C$, 16$0^{\circ}C$ in the PAAS LB films. Results of these measurements indicate that one peak at 8$0^{\circ}C$ is resulted from alkyl group; the other peak at 16$0^{\circ}C$ is due to alkyl and C-O group of PAAS. Additional large peak at about 16$0^{\circ}C$ is due to dipole moments in the PAAS films. The DSC and TGA of PAAS, arachidic acid and octadesylamine are measured. Thermal imidization was performed at 30$0^{\circ}C$ far 1 hour by our pre study

• 대한한의학회지
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• 제36권2호
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• pp.50-55
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• 2015

Infants with tuberous sclerosis complex (TSC) have a higher chance of experiencing seizures before the age of 1 year; in particular, they commonly accompany infantile spasms. In cases where infantile spasms resulting from TSC are drug-resistant, more severe neuro-developmental and cognitive impairments occur. This particular case dealt with an infant with TSC who continued to experience partial seizures and infantile spasms despite using two different kinds of antiepileptic drugs (AEDs). His spasms ceased on the seventh day of taking modified Yukmijihwang-tang (YMJ), at which point he stopped the use of all AEDs. He became seizure-free after a month of the treatment and modified hypsarrythmia was found to have been resolved in the electroencephalogram test. Until now, the infant has been taking YMJ for 16 months and is maintaining the seizure-free state without side effects. Moreover, his developmental status is continually improving, with a significant progress in language and cognitive-adaptive abilities. Such results suggest that YMJ can serve as an alternative treatment option for refractory epilepsy.

• 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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• 한국정보과학회언어공학연구회 2004년도 제16회 한글.언어.인지 한술대회
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• pp.12-19
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• 2004

기존의 다중 문서요약은 전체 대상문서에 대해서 한번에 요약문을 생산하지만, 본 논문은 요약 대상문서 집합에서 핵심내용을 갖는 문서를 기본 문서로 선택, 임시 요약문장을 추출하고 대상문서 집합에서 순차적으로 문서를 입력받아 중요문장을 추출, 이전에 구축된 요약문장과 현재 추출된 문장을 비교하면서 요약에 필요한 문장을 선택하는 적응 기법을 제안한다. 제안한 방법으로 구현한 시스템은 NTCIR TSC 3에서 사용된 29개의 다중 문서집합을 통해서 성능을 평가하였다. 적응 기법 시스템은 TSC3의 baseline시스템인 Lead 방법보다는 높은 성능을 나타냈지만, TSC 3에 참가한 시스템들과의 비교에서는 월등한 성능 우위를 나타내지 못했다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1992년도 춘계학술대회 논문집
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• pp.97-100
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• 1992

The Degradation mechanism of the ZnO-varistor fabricated with the content of a 3-Composition seed grain is discussed using the method of Thermally Stimulated Current (TSC). The spectra of TSC is measured in the temperature range of -130～270$^{\circ}C$ with a various forming electric fields E$\sub$f/, temperature T$\sub$f/ time tf, and a various rising rate of temperature. It is observed that there are appeared the peaks of ${\alpha}$, ${\alpha}$$_2$, ${\beta}$ and ${\gamma}$from high temperature in a TSC spectrum. It seems that ${\alpha}$$_1$ peak is due to thermal depolarization of donor ions forming the space charge in the depletion layer, and ${\alpha}$$_2$peak is due to the detrapping of trapped electrons in deep trap level of intergranular layer, and ${\beta}$ peak is due to the thermal exciting of carrier existing in the donor level of grain itself, and ${\gamma}$ peak is due to the thermal exciting of trapped carrier in all shallow trap site randomly distributed in the inner of sample and/or a intrinsic impurity existing in it.

• Journal of Electrical Engineering and Technology
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• 제13권3호
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• pp.1355-1362
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• 2018

In order to obtain a better understanding of the ageing process of the field composite insulators, it is necessary to explore a quantitative-valuation method for the aging state evaluation. And the linear relationship between volume resistivity and temperature is proposed. In this paper, the composite insulators with different lengths of operating lives from two manufacturers were tested. The relationship between trap characteristics and volume resistivity-temperature characteristics were analyzed based on Thermal Stimulated Current (TSC), volume resistivity-temperature test, Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Furthermore, the application of trap characteristics in the quantitative evaluation of aging state of composite insulators was discussed. The results showed that there was a general negative correlation between the relative variation ratio of trap charges and the volume resistivity-temperature characteristics. Meanwhile, the physicochemical properties would change with the aging time, which would result in the increasing of electron traps. Combined with the TSC and volume resistivity test results, the trap characteristic thresholds which indicated the serious age of the composite insulators had been proposed.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2014년도 전력전자학술대회 논문집
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• pp.51-52
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• 2014

전력계통은 전력수요의 지속적인 성장에 따라서 전력설비의 추가를 지속적으로 추진하고 있지만, 심해지는 환경문제 등으로 인해 용지 확보에 어려움이 있다. 이로 인해 송전선로 장거리화, 용량부족량 등 전력계통에 여러 가지 복잡한 문제가 야기되는데, 이것은 곧 전력계통의 안정도와 직결된다. 이러한 문제를 효과적이면서 경제적인 해결방법으로 FACT(Flexible AC Transmission System)기술이 주목 받고 있다. FACTS 기기 중 SVC(Static Var Compensator)는 상용운전 중이며, 기존 동기조상기에 비해 저렴하고, 신속 정확한 전압제어를 하는 장점이 있다. SVC는 TCR(Thyristor Controlled Reactor)과 TSC(Thyristor Switched Capacitor), FC(Fixed Capacitor)등 여러 종류의 구성을 가질 수 있다. TCR과 TSC는 실제 운전에 앞서 여러 가지 방법으로 검증이 필요하다. 합성 시험회로 설비(Synthetic Test Circuit)는 TCR과 TSC 안에 존재하는 Thyristor Valve의 동작을 실제 동작 조건으로 동작시켜, 동작의 신뢰성을 검증하는 설비이다. 본 논문에서는 TCR의 Operational Test를 위한 STC를 기술하고 있다. 설계된 STC는 PSCAD를 사용하여 검증하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 B
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• pp.1162-1164
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• 1993

The Thermally Stimulated Current(TSC) spectroscopy has been applied to study the influence of the structual cahange and interface on the electrical properties of epoxy composites. Three DGEBA-MeTHPA matrix model samples mixed different ratios and silica($SiO_2$) filled sample and silaln treating-filled sample has been studied. Above room temperature, the relaxation mode $\alpha$ peak associated with Tg has been located at $110^{\circ}C$. Below glass transition temperature(Tg), three relaxation modes are observed in all samples: a $\beta$ mode situated at $10^{\circ}C$, a $\gamma$ mode located at $-40^{\circ}C$ and a $\delta$ mode appeared in $-120^{\circ}C$. The analysis of its fine structure indicates that constitution of elementary processes is characterized by the activation energy and relaxation time. Also the dielectric relaxation properties have been investigated to compare the the change of the molecular structure and motion to the relaxation properties and conduction mechanism in TSC spectra.

• Earthquakes and Structures
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• 제18권6호
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• pp.709-718
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• 2020

Fragility curves are useful tools to estimate the damage probability of buildings owing to seismic actions. The purpose of this study is to investigate seismic vulnerability of reinforced concrete (RC) buildings, according to the 2007 and 2018 Turkish Seismic Codes, using fragility curves. For the numerical analyses, typical five- and seven-storey RC buildings were selected and incremental dynamic analyses (IDA) were performed. To complete the IDAs, eleven earthquake acceleration records multiplied by various scaling factors from 0.2g to 0.8g were used. To predict nonlinearity, a distributed hinge model that involves material and geometric nonlinearity of the structural members was used. Damages to confined concrete and reinforcement bar of structural members were obtained by considering the unit deformation demands of the 2007 Turkish Seismic Code (TSC-2007) and the 2018 Turkey Building Earthquake Code (TBEC-2018). Vulnerability evaluation of these buildings was performed using fragility curves based on the results of incremental dynamic analyses. Fragility curves were generated in terms of damage levels occurring in confined concrete and reinforcement bar of structural members with a lognormal distribution assumption. The fragility curves show that the probability of damage occurring is more according to TBEC-2018 than according to TSC-2007 for selected buildings.