• Progress in Medical Physics
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• v.14 no.4
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• pp.249-258
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• 2003

A few years ago, a proposal was made to change the dosimetry from the air kerma-based reference dosimetry to the absorbed dose-based reference dosimetry for all radiotherapy beams of ionizing radiation to improve the accuracy of dosimetry. Here, we present a dosimetry study in which the two most widespread absorbed dose­based protocols (IAEA TRS­398 and AAPM TG­51) were compared with an air kerma­based protocol (IAEA TRS-277) by measuring the absorbed dose in the same reference depth. Measurements were performed in three clinical electron beam energies using a PTW 30002 cylindrical chamber, and Markus and Roos plane­parallel chambers. $^{60}$ Co calibration factors were obtained from the KFDA. The absorbed dose differences between the air kerma­based and absorbed dose­based protocols were within 2.0% for all chambers in all beams. The results thus show that the obtained absolute dose values will be not significantly altered by changing from the air kerma­based dosimetry to the absorbed dose­based dosimetry. It was also shown that absorbed dose values between the absorbed dose­based protocols agreed by deviations of less than 0.5% for a cylindrical chamber and less than 0.7% for plane­parallel chambers using cross­calibration factors. Although the use of a cylindrical chamber and plane­parallel chambers resulted in a difference of less than 2% for all situations investigated here, to reduce errors, the plane­parallel chambers are recommended for electron energies in which the use of cylindrical chamber is not permitted in each protocol.

• Progress in Medical Physics
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• v.24 no.3
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• pp.140-144
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• 2013

In this research, the glass dosimeter was calibrated to measure the standard absorbed dose of the Cs-137 irradiator and absorbed dose in a biological sample. Absorbed dose in water for Cs-137 gamma ray was determined by the IAEA TRS-277 protocol. The PTW-TM30013 ion chamber and the PTW-TM41023 water phantom were utilized for measuring absorbed dose and the value was compared with the reading from DoseAce GD-302M glass dosimeter from Asahi Techno Glass Corporation for its calibration. The uncertainty of measurement ($1{\sigma}$) of the calibrated glass dosimeter was 2.7% and this result would be applied to improve the accuracy in measurement of absorbed dose in a biological sample.

• Progress in Medical Physics
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• v.25 no.3
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• pp.123-127
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• 2014

The Cs-137 irradiator is widely used to irradiate biological samples for radiobiological research. To obtain the accurate outcomes, correct measurements of the delivered absorbed dose to a sample is important. The IAEA protocols such as TRS-277 and TRS-398 were recommended for the Cs-137 reference dosimetry. However in TRS-398 protocol, currently known as the most practical dosimetry protocol, the quality factor ($k_{Q,Q_0}$) for Cs-137 gamma rays is not suggested. Therefore, the use of TRS-398 protocol is currently unavailable for the Cs-137 dosimetry directly. The calculation method previously introduced for high energy photon beams in radiotherapy was used for deriving the Cs-137 beam qualities ($k_{Q,Q_0}$) for the 15 commercially available farmer type ionization chambers in this study. In conclusion, $k_{Q,Q_0}$ values were ranged from 0.998 to 1.002 for Cs-137 gamma rays. These results can be used as the reference and dosimeter calibrations for Cs-137 gamma rays in the future radiobiological researches.

• Radiation Oncology Journal
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• v.20 no.4
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• pp.381-390
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• 2002

Purpose : To develop a dose calibration program for the IAEA TRS-277 and AAPM TG-21, based on the air kerma calibration factor (or the cavity-gas calibration factor), as well as for the IAEA TRS-398 and the AAPM TG-51, based on the absorbed dose to water calibration factor, so as to avoid the unwanted error associated with these calculation procedures. Materials and Methods : Currently, the most widely used dosimetry Protocols of high energy photon beams are the air kerma calibration factor based on the IAEA TRS-277 and the AAPM TG-21. However, this has somewhat complex formalism and limitations for the improvement of the accuracy due to uncertainties of the physical quantities. Recently, the IAEA and the AAPM published the absorbed dose to water calibration factor based, on the IAEA TRS-398 and the AAPM TG-51. The formalism and physical parameters were strictly applied to these four dose calibration programs. The tables and graphs of physical data and the information for ion chambers were numericalized for their incorporation into a database. These programs were developed user to be friendly, with the Visual $C^{++}$ language for their ease of use in a Windows environment according to the recommendation of each protocols. Results : The dose calibration programs for the high energy photon beams, developed for the four protocols, allow the input of informations about a dosimetry system, the characteristics of the beam quality, the measurement conditions and dosimetry results, to enable the minimization of any inter-user variations and errors, during the calculation procedure. Also, it was possible to compare the absorbed dose to water data of the four different protocols at a single reference points. Conclusion : Since this program expressed information in numerical and data-based forms for the physical parameter tables, graphs and of the ion chambers, the error associated with the procedures and different user could be solved. It was possible to analyze and compare the major difference for each dosimetry protocol, since the program was designed to be user friendly and to accurately calculate the correction factors and absorbed dose. It is expected that accurate dose calculations in high energy photon beams can be made by the users for selecting and performing the appropriate dosimetry protocol.

• Progress in Medical Physics
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• v.23 no.2
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• pp.114-122
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• 2012

For the determination of absorbed dose to water from a linear accelerator photon beams, it needs a exposure calibration factor $N_x$ or air kerma calibration factor $N_k$ of air ionization chamber. We used the exposure calibration factor $N_x$ to find the absorbed dose calibration factors of water in a reference source through the TG-21 and TRS-277 protocol. TG-21 used for determine the absorbed dose in accuracy, but it required complex calculations including the chamber dependent factors. The authors obtained the absorbed dose calibration factor $N_{dw}{^{Co-60}}$ for reduce the complex calculations with unknown $N_{dw}$ only with $N_x$ or $N_k$ calibration factor in a TM31010 (S/N 1055, 1057) ionization chambers. The results showed the uncertainty of calculated $N_{dw}$ of IC-15 which was known the $N_x$ and $N_{dw}$ is within -0.6% in TG-21, but 1.0% in TRS-277. and TM31010 was compared the $N_{dw}$ of SSDL to that of PSDL as shown the 0.4%, -2.8% uncertainty, respectively. The authors experimented with good agreement the calculated $N_{dw}$ is reliable for cross check the discrepancy of the calibration factor with unknown that of TM31010 and IC-15 chamber.