• Food Science of Animal Resources
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• v.31 no.3
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• pp.381-388
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• 2011

Dietary conjugated linoleic acid (CLA) play key roles in lipid metabolism. Here, we investigated the effect of CLA on the transcriptional activity of TR4, an orphan nuclear receptor that plays an important role in lipid homeostasis. CLA increased TR4 gene mRNA level in 3T3-L1 adipocytes, but inhibited TR4 transcriptional activity in a dose-dependent manner. TR4 induced perilipin expression in 3T3-L1 adipocytes by activating perilipin promoter activity. In a gel shift assay, TR4 bound direct to the putative TR4 response element in the perilipin promoter. Interestingly, CLA reduced the interaction between TR4 and consensus DR1, a well-known TR4 binding site. Additionally, CLA inhibited TR4-induced perilipin promoter activity in a dose-dependent manner. Together, our results suggest that CLA may play a role in lipid homeostasis in adipocytes by functionally regulating TR4.

• Korean Journal of Soil Science and Fertilizer
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• v.46 no.6
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• pp.563-569
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• 2013

This experiment was carried out to investigate the effect of liquid-pig-manure application method (Tr.1: surface appl. LPM 150%, Tr.2: surface appl. LPM 50% + LPM 50%, Tr.3: chemical fertilizer, Tr.4: soil injection LPM 150%, Tr.5: soil injection LPM 50% + surface appl. 50%, Tr.6: no fertilizer) and the economic efficiency of yield on forage crops cultivaion. In barley cultivation experiment, Tr.5 was found to be best, showing the yield of 1,462 kg $10a^{-1}$, and followed by Tr.2(1,226 kg $10a^{-1}$), Tr.3(1,226 kg $10a^{-1}$), Tr.4(1,225 kg $10a^{-1}$) and Tr.1(1,209 kg $10a^{-1}$) in order. In maize cultivation experiment, Tr.4 was found to be best, showing the yield of 2,142 kg/10a, and followed by Tr.1(2,125 kg $10a^{-1}$), Tr.3(2,024 kg $10a^{-1}$), Tr.5(2,011 kg $10a^{-1}$) and Tr.2(1,925 kg 1$10a^{-1}$) in order. The income was showing 1,274,000 ~ 1,591,000 Won $10a^{-1}$ in barley, whereas 766,000-794,000 Won 1$10a^{-1}$ in maize. There was more economical efficiency in barley cultivation than maize cultivation. Rather than the LPM surface application, LPM soil injection was more effective.

• Animal cells and systems
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• v.16 no.2
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• pp.87-94
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• 2012

Nur77 is a member of the nuclear receptor 4A (NR4A) subgroup, which has been implicated in energy metabolism. Although Nur77 is found in adipose tissue, where TR4 plays a key role in lipid homeostasis, the role of Nur77 in adipogenesis is still controversial. Although the Nur77 responsive element (AAAGGTCA) is partially overlapped with TR4-binding sites (AGGTCA $n$ AGGTCA: $n$=0-6), the regulatory role of Nur77 in TR4 function associated with adipocyte biology remains unclear. Here, we found that Nur77 inhibits adipogenesis and TR4 transcriptional activity. Treatment with a Nur77 agonist, 1,1-bis(3'-indolyl)-1-($p$-anisyl)-methane, during 3T3-L1 adipocyte differentiation reduced adipogenesis. In reporter gene analysis, Nur77 specifically suppressed TR4 transcription activity but had little effect on $PPAR{\gamma}$ transcription activity. Consistently, Nur77 also suppressed TR4-induced promoter activity of the TR4 target gene PEPCK, which is known to be important for glyceroneogenesis in adipose tissue. Furthermore, Nur77 suppressed TR4 binding to TR4 response elements without direct interaction with TR4, suggesting that Nur77 may inhibit TR4 transcription activity via binding competition for TR4-binding sites. Furthermore, DIM-C-$pPhOCH_3$ substantially suppressed TR4-induced PEPCK expression in 3T3-L1 adipocytes. Together, our data demonstrate that Nur77 plays an inhibitory role in TR4-induced PEPCK expression in 3T3-L1 adipocytes.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.1C
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• pp.81-89
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• 2009

We propose a D-ATR UWB (Differential-Average Transmitted Reference Ultra Wide Band) system based on impulse radio. The TR-UWB systems including traditional TR (Transmitted Reference) and ATR (Average TR), exhibit a problem of reduced data rate, since reference signals are additionally transmitted. To tackle this issue, the transmitter of the proposed D-ATR system employs a differential coding like the conventional D-TR system. In addition, the receiver of the proposed system has the structure that can improve signal-to-noise ratio of the reference template used in the correlation process, by recursively averaging the received reference signals like the conventional ATR system. The simulation results in the IEEE 802.15.4a UWB multipath channel models reveal that the proposed D-ATR system achieves much better bit error rate performance as compared to the conventional D- TR system.

• Electronics and Telecommunications Trends
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• v.34 no.5
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• pp.58-70
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• 2019

In this paper, we present the R&D status of ETRI's Trusted Reality (TR) project and its core technologies. ETRI's TR project focuses on the next-generation paradigm of smart phones, ETRI-TR Smart Glasses, which aims to provide the same features as those of smart phones without the involvement of any handheld device. Furthermore, they are characterized by additional features enabled by trustworthy VR/AR/MR/XR, such as privacy masking/unmasking, distributed structure of thin-client computing/networking among TR-Glasses, TR-LocalEdge, and TR-RemoteEdge, with novel see-through eyes-direct communication between IoT real/virtual objects and human eyes. Based on these core technologies of the ETRI's TR project, the human-held ETRI-TR Smart Glasses is expected to aid in the realization of XR vision with particularly more XR's safe_privacy on social life in the near future.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.3 s.234
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• pp.295-305
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• 2005

To improve the aerodynamic effciency of TR-E2, a new configuration so called TR-E2Sl was introduced. TR-2251 is composed of different wing airfoil section and T-tail shape compared with TR-E2. Wind tunnel test for TR-EBS1 had been performed by changing the incidence angles of wing and deflection angles of control surfaces such as elevator and rudder. Also the on/off effect of ventral fin attached underneath of AFT fuselage was tested. Test result showed that variations of wing incidence angle did not cause any severe differences in aerodynamic characteristics. Longitudinal and directional characteristics of TR-E2S1 show stable for the pitch and yaw motions. However, the lateral stability of TR-E2S1 is not stable for a certain control surface deflection.

• Journal of Sensor Science and Technology
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• v.12 no.1
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• pp.10-15
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• 2003

$PbTiO_3$/P(VDF/TrFE) thin film for pyroelectric infrared sensor's sensing materials have been fabricated by spin coating technique. 65 wt% VDF and 35 wt% TrFE were for P(VDF/TrFE) powder. $PbTiO_3$ powder was used for a ceramic - polymer composites materials. Surface of composite thin film by ceramic fraction factor was observed by SEM. The $PbTiO_3$/P(VDF/TrFE) thin film capacitancy, dielectric constant and dielectric loss measured by impedence analyzer(HP4192A) and pyroelectric coefficient was measured by semiconductor parameter analyzer(HP4145B).

• Food Science of Animal Resources
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• v.31 no.3
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• pp.398-404
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• 2011

TR4 has been suggested to play an important role in lipid metabolism in adipocytes. Although TR4 facilitates lipid accumulation during adipogenesis, the regulatory effect of TR4 on lipid storage in mature adipocytes remains unclear. We showed that TR4 inhibited the LXR agonist GW3965-mediated decrease of lipid accumulation in 3T3-L1 adipocytes. A reporter gene analysis revealed that TR4 suppressed LXR${\alpha}$ transcriptional activity, although LXR${\alpha}$ was unable to affect TR4 transcriptional activity. Moreover, adding TR4 resulted in reduced LXR${\alpha}$ binding to the LXR responsive element in a gel shift assay. Additionally, the suppressive effect of GW3965 on perilipin expression and lipid accumulation in 3T3-L1 adipocytes was abolished by TR4 overexpression. Taken together, our data demonstrate that TR4 plays an inhibitory role in LXR${\alpha}$-mediated suppression of lipid accumulation in 3T3-L1 adipocytes. This TR4 protective effect is mediated, in part, y blocking the suppressive effect of GW3965 on perilipin gene expression.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.5
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• pp.33-39
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• 2011

We studied the performance of a two-user time reversal multiple input single output scheme combined with the shifted transmission technique in a variable rate back-off scenario, called shifted time reversal (TR), that minimizes both intersymbol interference and multiuser interference. We compare the bit error rate performance of the shifted TR scheme to both full-rate TR and full back-off TR schemes and demonstrate its superiority to shifted zero forcing scheme when the guard interval is larger than one.

• Journal of architectural history
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• v.29 no.1
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• pp.21-37
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• 2020

The purpose of this paper is to reconstruct the original floor plan and wall design of Seokbulsa Grotto in Kyungju; commonly known as 'Seokguram'. The paper presents an array of dimensional studies of the existing Seokguram to examine its architectural form, and infers the original floor plan and wall design of Seokbulsa Grotto. Seokbulsa Grotto is designed as a system of 'coherent modules' and was constructed using the dry stone method, which interlocks large stone modules into a whole that becomes the load-bearing structure itself. The design principles governing Seokbulsa Grotto are the spatial axis of symmetry, modular coordination, and the layout grid of a quarter Tang-Ruler(TR: 唐尺). Dimensional studies were conducted with these governing principles in mind and concludes the following about the original floor plan design. In the main chamber, Ansang-stone's radius is 12 TR, and Flagstone's radius is 12¼ TR. In the front chamber, the width between the two Ansang-stones facing each other is 22 TR and the longitudinal space depth is 12 TR, while the width between the two Flagstones facing each other is 22½ TR and Flagstone's depth is 12 TR. In the passageway, the width between the two Ansang-stones facing each other is 11½ TR and longitudinal space depth is 9 TR, while the width between the two Flagstones facing each other is 12 TR and Flagstone's depth is 7¾ TR. The distance from the center to the entrance line of the main chamber is 10½ TR. Therefore, the total longitudinal length of the Grotto is 43½ TR at the level of the Ansang-stones, and 44 TR at the level of the Flagstones.