• Title/Summary/Keyword: TOTAL DEGRADATION

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Seismic Evaluation of Beam-Column Joint Specimens of RC Special Moment Frames (철근콘크리트 특수모멘트골조의 보-기둥 접합부 실험체의 내진성능평가)

  • Lee, Ki-Hak;Seok, Keun-Yung;Jung, Chan-Woo;Shin, Young-Shik;Kang, Joo-Won
    • Journal of Korean Association for Spatial Structures
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    • v.8 no.2
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    • pp.85-93
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    • 2008
  • This study summarizes the results of a research project aimed at investigating the inelastic rotation capacity of beam-column joints of reinforced concrete special moment frames. All of the test specimens were classified as special moment frame (SMF), based on the design and detailing requirements of the ACI 318-02 provisions. The acceptance criteria, originally defined for steel moment frame connections in the 1997 edition of the AISC Seismic provisions, were used to evaluate the beam-column joints of the reinforced concrete moment frames. A total of 39 test specimens were examined in detail. Most of the joints that satisfy the design requirements for special moment frame structures were found to be ductile up to a plastic rotation of 3% without any major degradation in strength. This is mainly due to the stringent ACI 318-02 requirements for special moment frame joints. The presence of transverse beams increases confinement and shear resistance of joints, which results in better performance than for joints without transverse beams. All of the SMF connections that satisfy the ACI 318-02 limitations on joint shear stress turned out to meet the acceptance criteria.

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Clinical Applications of Neuroimaging with Susceptibility Weighted Imaging: Review Article (SWI의 신경영상분야의 임상적 이용)

  • Roh, Keuntak;Kang, Hyunkoo;Kim, Injoong
    • Investigative Magnetic Resonance Imaging
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    • v.18 no.4
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    • pp.290-302
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    • 2014
  • Purpose : Susceptibility-weighted magnetic resonance (MR) sequence is three-dimensional (3D), spoiled gradient-echo pulse sequences that provide a high sensitivity for the detection of blood degradation products, calcifications, and iron deposits. This pictorial review is aimed at illustrating and discussing its main clinical applications. Materials and Methods: SWI is based on high-resolution, 3D, fully velocity-compensated gradient-echo sequences using both magnitude and phase images. To enhance the visibility of the venous structures, the magnitude images are multiplied with a phase mask generated from the filtered phase data, which are displayed at best after post-processing of the 3D dataset with the minimal intensity projection algorithm. A total of 200 patients underwent MR examinations that included SWI on a 3 tesla MR imager were enrolled. Results: SWI is very useful in detecting multiple brain disorders. Among the 200 patients, 80 showed developmental venous anomaly, 22 showed cavernous malformation, 12 showed calcifications in various conditions, 21 showed cerebrovascular accident with susceptibility vessel sign or microbleeds, 52 showed brain tumors, 2 showed diffuse axonal injury, 3 showed arteriovenous malformation, 5 showed dural arteriovenous fistula, 1 showed moyamoya disease, and 2 showed Parkinson's disease. Conclusion: SWI is useful in detecting occult low flow vascular lesions, calcification and microbleed and characterising diverse brain disorders.

Matrix Metalloproteinase-2 -1306 C>T Gene Polymorphism is Associated with Reduced Risk of Cancer: a Meta-analysis

  • Haque, Shafiul;Akhter, Naseem;Lohani, Mohtashim;Ali, Arif;Mandal, Raju K.
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.889-896
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    • 2015
  • Matrix metalloproteinase-2 (MMP2) is an endopeptidase, mainly responsible for degradation of extracellular matrix components, which plays an important role in cancer disease. A single nucleotide polymorphism (SNP) at -1306 disrupts a Sp1-type promoter site. The results from the published studies on the association between MMP2 -1306 C>T polymorphism and cancer risk are contradictory and inconclusive. In the present study, a meta-analysis was therefore performed to evaluate the strength of any association between the MMP2 -1306 C>T polymorphism and risk of cancer. We searched all eligible studies published on association between MMP2 -1306 C>T polymorphism and cancer risk in PubMed (Medline), EMBASE and Google Scholar online web databases until December 2013. Genotype distribution data were collected to calculate the pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) to examine the strength of the association. A total of 8,590 cancer cases and 9,601 controls were included from twenty nine eligible case control studies. Overall pooled analysis suggested significantly reduced risk associated with heterozygous genotype (CT vs CC: OR=0.758, 95%CI=0.637 to 0.902, p=0.002) and dominant model (TT+CT vs CC: OR=0.816, 95%CI=0.678 to 0.982, p=0.032) genetic models. However, allelic (T vs C: OR=0.882, 95%CI=0.738 to 1.055, p=0.169), homozygous (TT vs CC: OR=1.185, 95%CI=0.825 to 1.700, p=0.358) and recessive (TT vs CC+CT: OR=1.268, 95%CI=0.897 to 1.793, p=0.179) models did not show any risk. No evidence of publication bias was detected during the analysis. The results of present meta-analysis suggest that the MMP2 -1306 C>T polymorphism is significantly associated with reduced risk of cancer. However, further studies with consideration of different populations will be required to evaluate this relationship in more detail.

Sources and Distributions of Dissolved Organic Matter by Fluorescence Method in the Northeastern Pacific Ocean (북동태평양에서 형광 기법을 이용한 용존유기물의 기원 및 분포)

  • Son, Ju-Won;Son, Seung-Kyu;Ju, Se-Jong;Kim, Kyeong-Hong;Kim, Woong-Seo;Park, Yong-Chul
    • Ocean and Polar Research
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    • v.29 no.2
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    • pp.87-99
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    • 2007
  • This study was conducted to understand the source and behavior of organic matter using the fluorescent technique (excitation-emission matrix) as a part of environmental monitoring program in the Korea manganese nodule mining site in the Northeastern Pacific Ocean. Water samples were collected at $0^{\circ},\;6^{\circ}N$, and $10.5^{\circ}N$ along $131.5^{\circ}W$ in August 2005. The concentration of total organic carbon (TOC) ranged from 58.01 to $171.93\;{\mu}M-C$. The vertical distribution of TOC was characterized as higher in the surface layer and decreased with depth. At $6^{\circ}N$, depth-integrated (from surface to 200 m depth) TOC was $337.1\;gC/m^2$, which was 1.4 times higher value than other stations. The exponential decay curve fit of vertical profile of TOC indicated that 59% of organic carbon produced by primary production in the surface layer could be decomposed by bacteria in the water column. Dissolved organic matter is generally classified into two distinctive groups based on their fluorescence characteristics using three-dimensional excitation/emission (Ex/Em) fluorescence mapping technique. One is known as biomacromolecule (BM; protein-like substance; showing max. at Ex 280/Em 330), mainly originated from biological metabolism. The other is geomacromolecule (GM; humic-like substance; showing max. at Ex 330/Em 430), mainly originated from microbial degradation processes. The concentration of BM and GM was from 0.42 to 7.29 TU (tryptophan unit) and from 0.06 to 1.81 QSU (quinine sulfate unit), respectively. The vertical distribution of BM was similar to that of TOC as high in the surface and decreased with depth. However, the vertical distribution of GM showed the reverse pattern of that of BM. From these results, it appeared that BM occupied a major part of TOC and was rapidly consumed by bacteria in the surface layer. GM was mainly transformed from BM by microbial processes and was a dominant component of TOC in the deep-sea layer.

Replacing Concentrate with Wheat Straw Treated with Urea Molasses and Ensiled with Manure: Effects on Ruminal Characteristics, In situ Digestion Kinetics and Nitrogen Metabolism of Nili-Ravi Buffalo Bulls

  • Hassan, Z.;Nisa, M.;Shahzad, M.A.;Sarwar, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.8
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    • pp.1092-1099
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    • 2011
  • To evaluate the effects of replacing concentrate with urea molasses treated fermented wheat straw (FWS) ensiled with cattle manure (CM) on ruminal characteristics, in situ digestion kinetics and nitrogen (N) metabolism was studied in Nili Ravi cannulated buffalo bulls in a $4{\times}4$ Latin Square Design. Wheat straw treated with urea (4%) and molasses (6%) was ensiled with cattle manure (CM) (70:30) and fermented for 40 days. Four iso-nitrogenous and iso-caloric diets were formulated. In the FWS0, FWS10, FWS20 and FWS30 diets 0, 10, 20 and 30% of the concentrate was replaced with FWS, respectively. Daily intake by bulls was restricted to 1.5% dry matter (DM) of body weight. Ruminal ammonia nitrogen concentration was greater (p<0.05) in bulls fed FWS diet than for those fed FWS0 diet at 3, 6, 9 and 12 h post-parandial. Bulls fed FWS 20 and FWS 30 diets had higher ruminal pH at 3 and 6 h post-parandial than bulls fed FWS10 and FWS0. Ruminal total volatile fatty acid (VFA) concentrations 3 h post-parandial were greater (p<0.05) in bulls fed FWS0 than those fed FWS diets. However ruminal VFA tended to increase at 6, 9 and 12 h post-parandial as the level of FWS increased. In situ ruminal DM and neutral detergent fiber (NDF) degradation, rates of disappearance and extent of digestion were higher (p<0.05) for bulls fed FWS30 diet than those fed FWS0. Ruminal DM and NDF lag time tended to decrease (p<0.05) as FWS concentration in the diet increased. Feed intake, nitrogen intake, N-balance and blood urea-N did not differ (p>0.05) in buffalo bulls fed different diets. Wheat straw treated with urea and molasses and ensiled with CM enhanced the nutritive value of wheat straw and improved nutrient utilization in buffalo bulls when up to 30% of the concentrate was replaced with FWS; no adverse effects on ruminal characteristics and nutrients digestibilities were detected.

Effects of Pesticide Formulations on the Residues in Paddy Rice (농약(農藥)의 제형(劑型)이 수도체중(水稻體中) 잔류량(殘留量)에 미치는 영향(影響))

  • Oh, Byung-Youl;Kim, Young-Ku;Park, Young-Sun
    • Korean Journal of Environmental Agriculture
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    • v.3 no.2
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    • pp.1-8
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    • 1984
  • The present study was performed to elucidate pesticide residues in paddy rice applied with different application schedules and frequencies of pesticide formulations. Pungsanbyeo($Japonica{\times}Indica hybrid$) of rice(Oryza sativa L.) was chosen as target crop. Isoprothiolane(diisopropyl-l,3-dithiolan-2-ylidene malonate) 40EC (emulsifiable concentrates), 12G (granular), and chlorpyriphosmethyl [0,0-dimethyl 0-(3,5,6-trichloro-2-pyridyl) phosphorothioate] 25EC, 3G were selected as pesticide formulations. The closer the isoprothiolane EC application to harvest, the higher the residues in rice straw retained at harvest; however the G application on 30 days before harvest resulted in highest residue. Chlorpyriphosmethyl residues were higher as it was applied nearby to harvest. Degradation rate of chlorpyriphos-methyl in husked rice was quite similar to in rice straw, on the other hand isoprothiolane in the rice was more stable than that in rice straw. Translocated amount of applied G formulation to husked rice was meager irrespective to the chemicals. Percent reduction of isoprothiolane residues in husked rice by polishing was not related to application frequencies but to application date before harvest. Residual portions in rice straw, husked rice and polished rice of total input amount during rice cultivation were ranged from 0.19% to 0.99%, 0.01% to 0.48%, and 0.15%, respectively.

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Assessment of Forest Degradation and Carbon Storage for REDD+ Project in North Korea (북한에서의 REDD+ 사업을 위한 산림황폐화 및 탄소저장량 평가)

  • Piao, Dongfan;Lee, Woo-Kyun;Zhu, Yongyan;Kim, Moonil;Song, Cholho
    • Korean Journal of Environmental Biology
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    • v.34 no.1
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    • pp.1-7
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    • 2016
  • As the deforestation in North Korea gets severed, the interest for REDD+ is also increasing. This study analyzed historical land cover changes of the study area which is 10,000 ha in Hwanghaebukdo of North Korea for assessing change in landcover and carbon storage. The result showed that the forest area had decreased from 7,035 ha to 4,293 ha which is approximately 39% of total forest area between 1989 and 2013. The deforestation caused that forest carbon storage had decreased approximately $284,399tCO_2$. Set the baseline and analysed the potential reduction amount of carbon emission, it was estimated that REDD+ project could store approximately $364,704tCO_2$ for next 30 years. This study still has limitations such as lacking in direct field survey and the data of stand volume of each tree species which was replaced with the data of stand volume in South Korea. But, study can be applied for future REDD+ projects in North Korea.

Effect of Storage Temperature on the Physicochemical Characteristics in Kochujang(Red Pepper Soybean Paste) (저장온도에 따른 고추장의 품질변화)

  • Shin, Dong-Bin;Park, Woo-Mun;Yi, Ock-Sook;Koo, Min-Seon;Chung, Kun-Sub
    • Korean Journal of Food Science and Technology
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    • v.26 no.3
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    • pp.300-304
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    • 1994
  • To predict quality change of Kochujang distributed in the market, physicochemical properties were observed during storage at $13^{\circ}C$, $27^{\circ}C$ and $37^{\circ}C$ for 240 days. Moisture, crude protein and capsaicin contents were nearly constant for storage at the selected temperatures. Amino nitrogen, value of surface color and pH were decreased during storage while ammonia nitrogen and titratable acidity were increased. Storage temperature affected quality change significantly as higher temperature showed clear increase or decrease phenomena of above factors. Number of total cell count was not changed significantly, and fungi was not detected. From the correlation coefficient among physicochemical properties and sensory evaluation scores, the highest correlation was obtained in amino nitrogen content and sensory score. Degradation of amino nitrogen was a first order reaction, and the $Q_{10}$ value calculated from reaction constant was 2.98. Also, activation energy for the destruction of amino nitrogen calculated from Arrhenius equation was 15.34 Kcal/mole.

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Studies on Chung-Kook-Jang (Part I) -On the changes of soy-bean protein in manufacturing Chung-Kook-Jang- (청국장에 관한 연구(I) -청국장 제조과정에 있어서 콩단백질의 변화에 관하여-)

  • Lee, Ke-Ho;Lee, Hyo-Ji;Chung, Moon-Kyo
    • Applied Biological Chemistry
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    • v.14 no.3
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    • pp.191-200
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    • 1971
  • As a series on the soy-bean protein and their related substances 9 samples were collected from 9 places such as straws (Rice) to obtain bacterial strains which produce protease. From these samples total of 23 strains were isolated by the use of dilution pour plate method. For all isolated strains primary screening of productivity of protease was performed and useful straines with regard to protease productivities were identified. Optimum conditions for enzyme action of protease from isolates $D_9$, $F_{20}$ strains were pH 7.5 and $40^{\circ}C$. Chung-Kook-Jang is one of the characteristic foods in Korea made from soy-bean by fermentation. The chief bacterium is Bacillus subtilis and the chief change which takes place in soy-bean during fermentation is degradation of protein. Three kinds of Chung-Kook-Jang were prepared using three different strains of Bacillus natto, $D_9\;and\;F_{20}$ from isolated. Water soluble-N, TCA soluble-N, amino-N and peptide-N were measured about the steamed soybean, Chung-Kook-Jang prepared with three strains of bacteria. Water soluble-N decreased very largely in steamed soybean, but in Chung-Kook-Jang it increased to 85% of raw soy-bean.

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In vivo Metabolism of Endosulfan in Carp (cyprinus carpio L.) (In vivo 시험에 의한 잉어(cyprinus carpio L.)체내 endosulfan의 대사)

  • Lee, K.B.;Shim, J.H.;Suh, Y.T.
    • Applied Biological Chemistry
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    • v.37 no.3
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    • pp.194-202
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    • 1994
  • To study the metabolism and absorption of endosulfan in carp, $^{14}C-{\alpha}-endosulfan$ was treated with the $LC_{10}$ concentration $(4.5\;{\mu}g/L)$. In an in vivo test, endosulfan was metabolized $(65{\sim}80%)$ in tissues and endosulfan ether, endosulfan alcohol, endosulfan ${\alpha}-hydroxyether$, and endosulfan lactone were identified, indicating that those are the main metabolites of detoxification in carp. The maximum levels of $^{14}C-endosulfan$ in the head, muscle, and gut occurred after 8 hr exposure. However, the maxima reached in the liver and kidneys after 30 min and 4 hr, respectively. Radioactivity in the tissue decreased rapidly 8 hr after treatment. The total amount of $^{14}C-endosulfan$ recovered in the liver, kidneys and gut of fish was about $80{\sim}90%$ during the 8 hr treatment. The non-extractable radioactivity increased after 8 hr exposure $(27{\sim}31%)$. Endosulfan sulfate, the main degradation product in plant and mouse, was not detected during the test interval from tissues of the carp.

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