• Title/Summary/Keyword: TIF

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관상정맥동 천정결손증 3례 보고

  • 임창영;김요한;이인성;김광택;김형묵
    • Journal of Chest Surgery
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    • v.20 no.1
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    • pp.218-222
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    • 1987
  • Unroofed coronary sinus syndrome is an uncommon anomaly, Unroofed coronary sinus syndrome is caused by incomplete formation of the left atriovenous fold, and it usually is associated with Left SVC. If it is not diagnosed, a residual reversed or bidirectional shunt will result, and its complications will reduce life expectancy. We experienced 3 cases of unroofed coronary sinus syndrome which combines TOF with PLSVC, partial ECD, primum type ASD. In case of Unroofed coronary sinus syndrome which combines TIF with PLSVC, preoperative diagnosis was not made. In corrective operation for TOF of this case, pump weaning was failed due to hypoxia and cardiac arrest, and he expired at operation room. At autopsy of this case, complete unroofed coronary sinus was found. In the other 2 cases, partial unroofed coronary sinus syndrome was found in operation field and corrective operation was performed successfully. We report these 3 experiences with its review. ^u ++ Noninvasive Assessment of Pressure Gradients across Prosthetic Heart Valve by Doppler Ultrasound - A comparative study of the Duromedics Bileaflet Valves in mitral position and Normal Mitral Valves -with its review.

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KISTI-ACOMS를 기반으로 한 한국지하수토양환경학회 온라인논문투고관리

  • 박재원;강무영;김태중;김병규
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2003.09a
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    • pp.39-43
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    • 2003
  • 학회는 학술지식정보자원의 최신정보에 대한 접근 점이지만, 대규모 학회를 제외하고는 정보 수집과 서비스 면에서 재래식 방법을 벗어나지 못하고 있다. 더구나, 최근에는 각 학회 자체 업무 중 발생하는 회원관리, 논문투고, 심사와 같은 제반업무와, 발간되는 학술정보에 대한 정보화를 수행하고자 하는 학회의 열의가 급격히 증가하고 있는 추세이나, 학회의 재정상 적극적으로 이행하지 못하고 있는 실정이다. 이에 KISTI는 한국과학기술정보연구원은 국가차원의 학회 정보화 사업의 일환으로 학회정보 유통체제 전 과정을 온라인화하고 쉽게 관리할 수 있도록 한 $\boxDr$KISTI-ACOMS(KISTI-Article Contribution Management System: KISTI-학회논문투고관리시스템) $\boxDr$KISTI-ACOMS(KISTI-Article Contribution Management System)$\boxUl$ 을 개발하여 2001년부터 학회에 무상으로 보급하여 왔다. 최근에는 학회의 KISTI-ACOMS를 이용하고자 하는 요청이 더욱 확대되고 있어, KISTI는 많은 학회 특성을 의견수렴하여, KISTI-ACOMS의 표준화를 목표로 보완해 나가고 있다.

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Suppression of brown blotch disease by tolaasin inhibitory factors (톨라신 저해 물질을 이용한 갈반병의 억제)

  • Yun, Yeong-Bae;Kim, Min-Hee;Han, Ji-Hye;Kim, Young-Kee
    • Journal of Applied Biological Chemistry
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    • v.60 no.2
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    • pp.179-184
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    • 2017
  • Tolaasin, a 1.9 kDa peptide toxin, is produced by Pseudomonas tolaasii and causes the brown blotch disease of cultivated oyster mushroom. It forms pores on the membrane and thus destroys cellular membrane structure, seriously reducing the productivity of mushroom cultivation. The mechanism of tolaasin-induced cytotoxicity is not known in detail. However, it has been reported to form a pore structure in the cytoplasmic membrane through the molecular multimerization. Therefore, food additives which can interact with tolaasin molecules may inhibit the pore formation by hydrophobic interactions with tolaasin molecules. In this study, various food additive materials have been identified as inhibitors of the tolaasin activity and named tolaasin-inhibitory factors (TIF). Most of TIFs are emulsifying agents for food processing procedures. Among various TIFs, polyglycerol and sucrose esters of fatty acids blocked effectively the cytotoxicity of tolaasins at the concentrations $10^{-4}-10^{-5}M$. These TIFs also successfully suppressed the blotch disease development in the shelf cultivation of oyster mushroom.

Differential gene expression pattern in brains of acrylamide-administered mice

  • Han, Chang-Hoon
    • Korean Journal of Veterinary Research
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    • v.52 no.2
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    • pp.99-104
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    • 2012
  • The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that the group treated with higher than 30 mg/kg/day of acrylamide caused impaired motor activity in mice. Based on cDNA microarray analysis of mouse brain, myelin basic protein gene, kinesin family member 5B gene, and fibroblast growth factor (FGF) 1 and its receptor genes were down-regulated by acrylamide. The genes are known to be essential for neurofilament synthesis, axonal transport, and neuroprotection, respectively. Interestingly, both FGF 1 and its receptor genes were down-regulated. Genes involved in nucleic acid binding such as AU RNA binding protein/enoyl-coA hydratase, translation initiation factor (TIF) 2 alpha kinase 4, activating transcription factor 2, and U2AF 1 related sequence 1 genes were down-regulated. More interesting finding was that genes of both catalytic and regulatory subunit of protein phosphatases which are important for signal transduction pathways were down-regulated. Here, we propose that acrylamide induces neurotoxicity by regulation of genes associated with neurofilament synthesis, axonal transport, neuro-protection, and signal transduction pathways.

Improvement of the Biosensor for Detection of Endocrine Disruptors by Combination of Human Estrogen Receptorα and Co-Activator (Human Estrogen Receptor α와 Co-activator로 구성된 바이오센서를 이용한 내분비계장애물질의 검출)

  • Lee, Haeng-Seog
    • Journal of Korean Society of Water and Wastewater
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    • v.20 no.6
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    • pp.893-904
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    • 2006
  • To improve sensitivity of biosensor as yeast two-hybrid detection system for estrogenic activity of suspected chemicals, we tested effects of several combinations of the bait and fish components in the two-hybrid system on Saccharomyces cerevisiae inducted a chromosome-integrated lacZ reporter gene that was under the control of CYC1 promoter and the upstream Gal4p-binding element $UAS_{GAL}$. The bait components that were fused with the Gal4p DNA binding domain are full-length human estrogen receptor ${\alpha}$ and its ligand-binding domain. The fish components that were fused with the Gal4p transcriptional activation domain were nuclear receptor-binding domains of co-activators SRC1 and TIF2. We found that the combination of the full-length human estrogen receptor ${\alpha}$ with the nuclear receptor-binding domain of co-activator SRC1 was most effective for the estrogen-dependent induction of reporter activity among the two-hybrid systems so far reported. The relative strength of transcriptional activation by representative natural and xenobiotic chemicals was well correlated with their estrogenic potency that had been reported with other assay systems.

Tracheoplasty with using the Costal Cartilage, Including the Perichondrium, for Treating a Tracheoinnominate Artery Fistula - Surgical experience of one case - (기관절개술 후 발생한 기관무명동맥루에서 연골막를 포함한 늑연골을 이용한 기관성형술 - 수술치험 1예 -)

  • Cho, Seong-Ho;Kae, Yoe-Kon;Kim, Jong-In;Cho, Sung-Rae
    • Journal of Chest Surgery
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    • v.40 no.9
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    • pp.651-654
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    • 2007
  • Tracheoinnominate artery fistula (TIF) is a very rare complication that can happen after long standing tracheostomy or insertion of an endotracheal tube and its mortality is very high. This condition requires early diagnosis and urgent management because of the life threatening results from tracheal obstruction or hypovolemic shock that is caused by massive bleeding. We report here on a case of successful tracheoplasty with using the costal cartilage, including the perichondrium, in a patient with laryngeal stricture, and this was done to preserve the trachea for the following operation to relieve the laryngeal stricture.

Deterministic Pitch Tool Polishing Using Tool Influence Function (드레이퍼 방식 연마기에서의 툴 영향 함수 기법)

  • Yi, Hyun-Su;Yang, Ho-Soon;Lee, Yun-Woo;Kim, Sug-Whan
    • Korean Journal of Optics and Photonics
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    • v.19 no.6
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    • pp.422-428
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    • 2008
  • The pitch tool provides superior surface roughness compared to other types of polishing tool. However, because of difficulty in handling the pitch tool, pitch tool polishing has rarely been analysed, which led many craftsman to eliminate the pitch tool from their experiences. We found that it was possible to use a pitch tool in the well-determined material removal after the completion of computer simulation and experiment. We could simulate the TIF of the pitch tool with 79% accuracy. Also, after five successive simulations of polishing process on a 280 mm optical flat, the surface p-v error was found to be reduced from $1{\mu}m$ to 168 nm.

Modeling of Various Tool Influence Functions in Computer Controlled Optical Surfacing (컴퓨터 제어를 통한 광학 가공에서의 다양한 툴 영향 함수의 모델링)

  • Kim, Gi-Chul;Ghim, Young-Sik;Rhee, Hyug-Gyo;Kim, Hak-Sung;Yang, Ho-Soon;Lee, Yun-Woo
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.3
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    • pp.167-172
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    • 2016
  • The computer controlled optical surfacing (CCOS) technique provides superior fabrication performance for optical mirrors when compared to the conventional method, which relies heavily on the skill of the optician. The CCOS technique provides improvements in terms of mass production, low cost, and short polishing time, and are achieved by estimating and controlling the moving speed of the tool and toolpath through a numerical analysis of the tool influence function (TIF). Hence, the exact estimation of various TIFs is critical for high convergence rates and high form accuracy in the CCOS process. In this paper, we suggest a new model for TIFs, which can be applied for various tool shapes, different velocity distributions, and non-uniform tool pressure distributions. Our proposed TIFs were also verified by comparisons with experimental results. We anticipate that these new TIFs will have a major role in improving the form accuracy and shortening the polishing time by increasing the accuracy of the material removal rate.

Construction of NCAM-LAMP Precipitation and Soil Moisture Database to Support Landslide Prediction (산사태 예측을 위한 NCAM-LAMP 강수 및 토양수분 DB 구축)

  • So, Yun-Yeong;Lee, Su-Jung;Choi, Sung-Won;Lee, Seung-Jae
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.22 no.3
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    • pp.152-163
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    • 2020
  • The present study introduces a procedure to prepare and manage a high-resolution rainfall and soil moisture (SM) database in the LAMP prediction system, especially for landslide researchers. The procedure also includes converting the data into spatial resolution suitable for their interest regions following proper map projection methods. The LAMP model precipitation and SM data are quantitatively and qualitatively evaluated to identify the model prediction characteristics using the ERA5 reanalysis precipitation and observed 10m depth SM data. A detailed process of converting LAMP Weather Research and Forecasting (WRF) output data for 10m horizontal resolution is described in a step-wise manner, providing technical convenience for users to easily convert NetCDF data from the WRF model into TIF data in ArcGIS. The converted data can be viewed and downloaded via the LAMP website (http://df.ncam.kr/lamp/index.do) of the National Center for AgroMeteorology. The constructed database will contribute to monitoring and prediction of landslide risk prior to landslide response steps and should be data quality controlled by more observation data.

Induction of Genetic Variation with Recurrent Gamma Radiation in Centipedegrass (Eremochloa ophiuroides) (감마선 순환 처리에 의한 Centipedegrass (Eremochloa ophiuroides)의 유전변이 유도)

  • Lim, Keun Bal;Hanna, Wayne. W.;Rim, Yong Woo;Kim, Young Jin;Han, Hak Suk;Sung, Byung Ryeol;Kim, Jun Sik
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.18 no.4
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    • pp.351-354
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    • 1998
  • Centipedegrass (Eremochloa ophiuroides) is a popular lawn grass in the southeastern USA. It has a naturally light green color and grows well on a wide range of soil types. Studies show limited morphological variation present in centipedegrass germplasm. To obtain the high morphological variation, plants were established from the irradiated seed at 10 Kr, allowed to interpollinate and harvested bulk seed, and then irradiated again for the next cycles. Morphological characteristics were measured in the 5 genetic varition lines (TC201 : cv. Common and non irradiated, TC202 : 4th cycles, TC241 : 6th cycles, TC306 : 8th cycles, and TC318 : 5th cycles) induced by recurrent gamma radiation. The ranges of variation of recurrently radiated centipedegrass lines < TC202, TC241 and TC306 except TC318(TifBlair) > for the stolons per plant, total stolon length per plant, longest stolon length, leaf length and width at top-most exposed internode were wider than those of non-irradiated line (TC201). Recurrent gamma radiation was very effective to enlarge the ranges of variation of morphological characteristics in reproductive organ like stolons of centipedegrass. The effect of quantity of gamma ray irradiation cycles on the means and ranges of variation in the morphological characteristics of centipedegrass was not regularly tended.

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