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MC3T3-E1 osteoblast adhesion to laser induced hydroxyapatite coating on Ti alloy

  • Huang, Lu;Goddard, Samuel C.;Soundarapandian, Santhanakrishnan;Cao, Yu;Dahotre, Narendra B.;He, Wei
    • Biomaterials and Biomechanics in Bioengineering
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    • 제1권2호
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    • pp.81-93
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    • 2014
  • An in vitro cell study evaluating cell adhesion to hydroxyapatite (HA) coated prosthetic Ti-6Al-4V alloy via laser treatment is presented in comparison with uncoated alloy. Based on our previous in vitro biocompatibility study, which demonstrated higher cell attachment and proliferation with MC3T3-E1 preosteoblast cells, the present investigation aims to reveal the effect of laser coating Ti alloy with HA on the adhesion strength of bone-forming cells against centrifugal forces. Remaining cells on different substrates after centrifugation were visualized using fluorescent staining. Semi-quantifications on the numbers of cells were conducted based on fluorescent images, which demonstrated higher numbers of cells retained on HA laser treated substrates post centrifugation. The results indicate potential increase in the normalized maximum force required to displace cells from HA coated surfaces versus uncoated control surface. The possible mechanisms that govern the enhancing effect were discussed, including surface roughness, chemistry, wettability, and protein adsorption. The improvement in cell adhesion through laser treatment with a biomimetic coating could be useful in reducing tissue damage at the prosthetic to bone junction and minimizing the loosening of prosthetics over time.

TIMES: mapping Turbulent properties In star-forming MolEcular clouds down to the Sonic scale. I. the first result.

  • Yun, Hyeong-Sik;Lee, Jeong-Eun;Choi, Yunhee;Evans, Neal J. II;Offner, Stella S.R.;Lee, Yong-Hee;Baek, Giseon;Choi, Minho;Kang, Hyunwoo;Lee, Seokho;Tatematsu, Ken'ichi;Heyer, Mark H.;Gaches, Brandt A.L.;Yang, Yao-Lun;Jung, Jae Hoon;Lee, Changhoon
    • 천문학회보
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    • 제44권1호
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    • pp.42.2-42.2
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    • 2019
  • Turbulence is one of the natural phenomena in molecular clouds. It affects gas density and velocity fluctuation within the molecular clouds and controls the mode and tempo of star formation. However, despite many years of study, the properties of turbulence remain poorly understood. As part of the Taeduk Radio Astronomy Observatory (TRAO) Key Science Program (KSP), "mapping Turbulent properties In star-forming MolEcular clouds down to the Sonic scale (TIMES; PI: Jeong-Eun Lee)", we have fully mapped two star-forming molecular clouds, the Orion A and the Ophiuchus molecular clouds, in 3 sets of lines ($^{13}CO$ J=1-0, $C^{18}O$ J=1-0, HCN J=1-0, $HCO^+$ J=1-0, CS J=2-1, and $N_2H^+$ J=1-0) using the TRAO 14-m telescope. We apply a statistical analysis, Principal Component Analysis (PCA), which can recover an underlying turbulent-power spectrum from an observed P-P-V spectral map. We compare turbulence properties not only between the two clouds, but also between different parts within each cloud. We present the first result of our observation program.

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Optomechanical Design and Structure Analysis of Prototype Siderostat for Testing Local Volume Mapper Telescope Control System

  • Lee, Sunwoo;Han, Jimin;Ahn, Hojae;Kim, Changgon;Yang, Mingyeong;Ji, Tae-geun;Lee, Sumin;Kim, Taeeun;Pak, Soojong;Konidaris, Nicholas P.;Drory, Niv;Froning, Cynthia S.;Hebert, Anthony;Bilgi, Pavan;Blanc, Guillermo A.;Lanz, Alicia E.;Hull, Charles L;Kollmeier, Juna A.;Ramirez, Solange;Wachter, Stefanie;Kreckel, Kathryn;Pellegrini, Eric;Almeida, Andr'es;Case, Scott;Zhelem, Ross;Feger, Tobias;Lawrence, Jon;Lesser, Michael;Herbst, Tom;Sanchez-Gallego, Jose;Bershady, Matthew A;Chattopadhyay, Sabyasachi;Hauser, Andrew;Smith, Michael;Wolf, Marsha J;Yan, Renbin
    • 천문학회보
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    • 제46권1호
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    • pp.38.4-39
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    • 2021
  • The Local Volume Mapper (LVM), for the Sloan Digital Sky Survey V, consists of four 16 cm telescopes with three fiber spectrographs in the Las Campanas Observatory in Chile. With the fixed telescopes on optical tables, the Alt-Alt mounted siderostats point and guide targets during spectrograph exposures. We are developing the integrated LVM instrument control software. Considering international travel restrictions caused by the COVID-19 pandemic in 2021, we decided to make a simplified version of siderostat to test the LVM telescope control system in Korea. The prototype siderostat consists of two aluminum flat mirrors, optomechanical housing structures made by aluminum profiles, and the Planewave L-350 mount. We designed the optical mirrors and the optomechanical structure of the siderostat. From structural analysis at various pointing cases, we estimated the tilt misalignments of mirrors within 4 arcsec, which would affect the telescope pointing errors.

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Brightness Improvement of ZnS:Cu Powder Electroluminescence by Mixed Layer

  • Lee, Jong-Chan;Park, Dae-Hee
    • KIEE International Transactions on Electrophysics and Applications
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    • 제4C권2호
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    • pp.64-67
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    • 2004
  • In this paper, to discover the brightness improvement of ZnS:Cu powder electroluminescence (EL), a new structure is proposed in which phosphor and dielectric are mixed between electrodes. Dielectric and phosphor material are BaTiO$_3$ and ZnS:Cu, respectively. The effect of the mixed layer on EL sample is considered the improvement of source efficiency. Although the number of electrons introduced into the phosphor increases only modestly, the high electric field region of phosphor grains increases comparatively in the characteristics of brightness-voltage. Furthermore, the relaxation occurs through leading and trailing edge pairs, which is relatively efficient in characteristics of decay time. With these results, we found that the brightness of newly proposed ZnS:Cu powder electroluminescence was 167.24 cd/$m^2$ at ac voltage of 100V and frequency of 400Hz.

IGRINS observations toward Class I disk sources, IRAS03445+3242 and IRAS0429+2436

  • Lee, Seokho;Lee, Jeong-Eun;Park, Sunkyung;Jaffe, Daniel T.
    • 천문학회보
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    • 제40권1호
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    • pp.67.3-67.3
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    • 2015
  • We present the high-resolution Immersion GRating INfrared Spectrograph (IGRINS) spectra of two Class I sources, IRAS03445+3242 and IRAS04239+2436. Both sources show the evidence of Keplerian disks; the broadened CO overtone (${\Delta}v=2$) transitions in emission and neutral metal lines (Mg I, Fe I, and Al I) in absorption. The thin Keplerian disk with a rotational velocity of ~100 km s-1 and a gas temperature of 5000 K at the innermost annulus can reproduce the CO overtone transitions including the bandhead emission. The outer dusty disk or the envelope needs to fit the narrow absorption features overlaid on the broad emission lines in the CO overtone transitions.

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Design Considerations for Auto-Connected Multi-Pulse Rectiviers for High Power AC Motor Drives

  • 이방섭
    • 전력전자학회논문지
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    • 제4권5호
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    • pp.413-422
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    • 1999
  • Auto-connected multipulse(12/24pulse) rectifier schemes are cost effective methods for reducing line current hamonics in PWM drive systems. Employing these schemes to enhance utility power quality requires careful attention to several design considerations In particular, excursion of dc-link voltage at no load, effect of pre-existing voltage distortion, impedance mismatches, unequal diode drops on rectifier current sharing and performance, are fully analyzed, Several corrective measures to improve the performance of 12/24­pulse rectifier systems are also discussed. Finally, experimental results on a 460V, 60Hz 400kVA commercial ASD, retrofitted with 12/24pulse rectifier systems are discussed in detail.

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IGRINS Exposure Time Calculator

  • Le, Huynh Anh Nguyen;Pak, Soojong;Sim, Chae Kyung;Jaffe, Daniel T.
    • 천문학회보
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    • 제38권2호
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    • pp.62.1-62.1
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    • 2013
  • We present the Exposure Time Calculator of IGRINS (Immersion Grating Infrared Spectrograph). The noises of IGRINS and the simulated emission line can be calculated from the combination of Telluric background emission and absorptions, the emission and transmission of the telescope and instrument optics, and the dark noise and the read noise of the infrared arrays. For the atmospheric transmissions, we apply the simulated spectra depending on the Precipitable Water Vapor (PWV) values. In case of calculation of noises, the user needs to input the expected target magnitude, the weather conditions, and the desired exposure time. In addition to the simulated emission line, the parameters of rest wavelength, line-flux, Doppler shift and line-width are needed. The output would be the expected signal-to-noise for each spectral resolution element. The source-code of IGRINS-ETC v2.1.1 is available to be downloaded on the World Wide Web.

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A study of internal wave influence on OTEC systems

  • Shi, Shan;Kurup, Nishu V.;Halkyard, John;Jiang, Lei
    • Ocean Systems Engineering
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    • 제3권4호
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    • pp.309-325
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    • 2013
  • Ocean Thermal Energy Conversion (OTEC) systems utilize the temperature difference between the surface water and deep ocean water to generate electrical energy. In addition to ocean surface waves, wind and current, in certain locations like the Andaman Sea, Sulu Sea and the South China Sea the presence of strong internal waves may become a concern in floating OTEC system design. The current paper focuses on studying the dependence of the CWP hydrodynamic drag on relative velocity of the flow around the pipe, the effect of drag amplification due to vortex induced vibrations and the influence of internal waves on the floating semi and the cold water pipe integrated OTEC system. Two CWP sizes are modeled; the 4m diameter pipe represents a small scale prototype and the 10m diameter pipe represents a full commercial size CWP. are considered in the study.

Incorporating nonstructural finish effects and construction quality in a performance-based framework for wood shearwall design

  • Kim, Jun Hee;Rosowsky, David V.
    • Structural Engineering and Mechanics
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    • 제21권1호
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    • pp.83-100
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    • 2005
  • This paper presents results from a study to extend a performance-based shearwall selection procedure to take into account the contributions of nonstructural finish materials (such as stucco and gypsum wallboard), construction quality issues, and their effects on the displacement performance of engineered wood shearwalls subject to seismic loading. Shearwall performance is evaluated in terms of peak displacements under seismic loading (characterized by a suite of ordinary ground motion records) considering different combinations of performance levels (drift limits) and seismic hazard. Shearwalls are analyzed using nonlinear dynamic time-history analysis with global assembly hysteretic parameters determined by fitting to actual shearwall test data. Peak displacement distributions, determined from sets of analyses using each of the ground motion records taken to characterize the seismic hazard, are postprocessed into performance curves, design charts, and fragility curves which can be used for risk-based design and assessment applications.

Developing the Entrepreneurial University: Architecture and Institutional Theory

  • Gibson, David V.;Foss, Lene
    • World Technopolis Review
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    • 제6권1호
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    • pp.3.1-3.15
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    • 2017
  • Given the diverse environmental contexts of universities worldwide there is a need for a theoretical orientation that addresses the entrepreneurial university in a range of settings. Applying the institutional perspective this research explores how universities are strongly influenced by, as well as active influencers in, their surrounding environment. To do this, we examine case narratives of two universities in each of the following countries: Norway, Sweden, Finland, the UK, and the U.S. Analysis focuses on five entrepreneurial dimensions as defined by Nelles and Vorley (2010a): Structures, Systems, Leadership, Strategies, and Culture while examining the impact of regional and national context at regulative, normative, and cognitive levels of analysis. We address two research questions: How do universities interact with their institutional context in developing entrepreneurially and what actors and forces are most important in motivating institutional change in developing a university's entrepreneurial architecture?