• BMB Reports
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• v.47 no.11
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• pp.609-618
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• 2014

DNA methylation at cytosines (5mC) is a major epigenetic modification involved in the regulation of multiple biological processes in mammals. How methylation is reversed was until recently poorly understood. The family of dioxygenases commonly known as Ten-eleven translocation (Tet) proteins are responsible for the oxidation of 5mC into three new forms, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). Current models link Tet-mediated 5mC oxidation with active DNA demethylation. The higher oxidation products (5fC and 5caC) are recognized and excised by the DNA glycosylase TDG via the base excision repair pathway. Like DNA methyltransferases, Tet enzymes are important for embryonic development. We will examine the mechanism and biological significance of Tet-mediated 5mC oxidation in the context of pronuclear DNA demethylation in mouse early embryos. In contrast to its role in active demethylation in the germ cells and early embryo, a number of lines of evidence suggest that the intragenic 5hmC present in brain may act as a stable mark instead. This short review explores mechanistic aspects of TET oxidation activity, the impact Tet enzymes have on epigenome organization and their contribution to the regulation of early embryonic and neuronal development.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.1
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• pp.36.2-36.2
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• 2012

The aim of this study was to explore the role of galaxy mergers on the formation and evolution of galaxies in galaxy clusters. For this purpose, u', g', r' deep optical imaging and multi-object spectroscopic observation were done for four rich Abell clusters at z ${\lesssim}$ 0.1 (A119, A2670, A3330, and A389) with a MOSAIC 2 CCD and Hydra spectrograph mounted on a Blanco 4-m telescope at CTIO. With the deep images, we found that about 25% of the bright red-sequence galaxies exhibited post-merger signatures in a cluster environment. This fraction was much higher than what was expected from the results of the field environment (-35%, van Dokkum 2005) and significantly low on-going merger fractions (about one-fifth of the field) appeared in the clusters currently. Taking advantage of the most up-to-date semi-analytic model, the results indicate that most of the post-merger galaxies may have carried over their merger features from their previous halo environment. All the brightest cluster galaxies in our cluster samples revealed faint structures in their halos as well as multiple nuclei in their centers seen in the deep optical images. We suggest that the mass of the BCGs increased mainly though major mergers at recent epochs based on their post-merger signatures and the large gaps in the total magnitudes between the BCGs and the second-rank BCGs. A UV bright tidal tail and tidal dwarf galaxy (TDG) candidates around the post-merger galaxy, NGC 4922, were discovered in the outskirts of the Coma cluster using the GALEX UV data. We did two-component stellar population modeling for the TDG candidates and the results indicate that they are an early form of dwarf galaxies frequently found around massive early-type galaxies in clusters. In conclusion, we suggest that the mergers of galaxies are an important driving force behind galaxy formation and evolution in cluster environments even until recent epochs.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.34.2-34.2
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• 2013

Star formation beyond the galaxy discs and the principles governing it have attracted a lot of recent attention and the advent of ultraviolet (UV) and mid-infrared (MIR) telescopes like the GALEX and Spitzer have enabled major advances in such studies. In order to study the HI gas properties such as the morphology, kinematics and column density distributions, and their correlation with the star forming zones, especially in the tidal bridges, tails and debris, we carried out an HI survey of a set of Spitzer-observed interacting systems using the Giant Metrewave Radio Telescope (GMRT). Here we present results from three of these systems, Arp86, Arp181 and Arp202. In Arp86, we detect excellent star-gas correlation in the star forming tidal bridges and tails. In Arp181, we find the two interacting galaxies to be highly gas depleted and the entire gas of the system is found in the form of a massive tidal debris about 70 kpc from the main galaxies. In all three cases, Arp86, Arp181 and Arp202, the tidal debris seem to host ongoing star formation. We also detect three new candidate tidal dwarf galaxies (TDG) in these systems with large quantities of gas associated with them.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.60.2-60.2
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• 2018

We present the near infrared JHK photometric properties and the spatial distribution of red supergiants(RSGs) of NGC 3623, NGC 3627 and NGC 3628 in the Leo Triplet system using the data obtained with 3.8m UKIRT(United Kingdom Infra-Red Telescope) at Hawaii. We checked interaction between the three galaxies by making a spatial density map of RSGs. From (J-K,K)0 Color-Magnitude Diagram which include resolved stars in three galaxy and control field with PARSEC isochrone, we figured out the RSG candidates of the Leo triplet are at 0.9<(J-K)0<1.2, mK<17.5 and separated them from background and foreground sources. Using gaussian kernel density estimation, we drew spatial density map of RSGs in the Leo triplet with an assumption that all RSGs are an identical population. The density map shows extended features of NGC 3628 to NGC 3627 along the declination direction. The asymmetries between NGC 3627 and NGC 3628 might be evidence for that the distribution of actual star components(RSGs) follows the neutral hydrogen distribution and also for interaction between two galaxies. And the extended features along the right ascension direction might be a supporting evidence for the existence of a TDG(Tidal Dwarf Galaxy). In case of NGC 3623, we could not see any sign of interaction in density map.

• Proceedings of the KIEE Conference
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• summer
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• pp.845-847
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• 2004

단락시험시 시험회로의 주요 파라미터들은 시험전압과 시험전류를 이용하여 결정된다. 특히, 단락전류의 경우 전류파형의 피크치, RMS, 시간, DC-성분, 역률 등을 분석프로그램을 이용하여 분석하게 된다. 그러나 이러한 분석프로그램은 각 시험기관마다 다르고, 현재까지 분석프로그램을 검증할 국제저인 기준이 존재하지 않았다. 그러나 최근 들어 STL(Short-circuit Testing Liason)에서는 각 시험기관마다 상이한 분석프로그램을 검증할 절차에 대한 연구를 수행하여 왔으며 그 첫 번째로 단락전류 분석프로그램에 대한 성능 평가 절차가 어느 정도 완성되었다. 이에 본 논문에서는 STL에서 배포한 TDG(Test Data Generator)를 이용해reference curve를 생성하고, 전기연구원의 전류분석프로그램을 사용하여 분석프로그램의 신뢰성을 평가하여 보았다.