• Journal of Society of Preventive Korean Medicine
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• v.18 no.1
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• pp.11-21
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• 2014

Objective : This study set out to combine the treatment efficacy of Taraxacum with Dongchimi fermentation and investigate Taraxacum's effects on protection of liver cell and controlling nitric oxide(NO) through experiments, thus checking whether it had values as a physiological active matter. The experimental materials include Taraxacum Dongchimi (TD) and Taraxacum fermented by Dongchimi (TDF). As for methodology, experiments were carried out to compare TD and TDF in components, protection effects for liver cells, anticancer effects on liver cells, and protection effects for brain cells in the aspects of liver function and immunity enhancement. Method : The experimental materials include Taraxacum Dongchimi (TD) and Taraxacum fermented by Dongchimi (TDF). As for methodology, experiments were carried out to compare TD and TDF in components, protection effects for liver cells, anti-cancer effects on liver cells, and protection effects for brain cells in the aspects of liver function and immunity enhancement. Results : As shown in the chromatogram results, each valid component content increased in Taraxacum fermented by Dongchimi (TDF) for each time section. Of them, the valid component content at 36.80 minutes was approximately 2.7 times higher in TDF at 21.8% than in Taraxacum Dongchimi (TD) at 8.28%. TDF generated more excellent protection effects against the toxicity that caused oxidative damage to the liver cell(HepG2) with t-BHP than TD. The survival rate was low in TD of $100{\mu}g/m{\ell}$ and $300{\mu}g/m{\ell}$ and increased to 23.3% in TDF of $100{\mu}g/m{\ell}$. The survival rate was the highest at $300{\mu}M$ with a significant difference of 68.1%(P<0.05). Both TD and TDF showed effects of controlling nitric oxide production according to concentration with TDF recording a higher rate of controlling nitric oxide production than TD. There were significant differences(P<0.05) in the effects of controlling nitric oxide production at 200 ug/ml, 400 ug/ml in both groups. Especially the result TDF of $400{\mu}g/m{\ell}$ was thus similar to those of butein, the positive control group. Conclusion : The result of this studies is that Taraxacum fermented by Dongchimi (TDF) increased the valid component content compared with the simple mixture(TD). The findings clearly show that it is a material with the effects of improving immunity and liver cell protection. If fermentation methods are further developed to use it as a functional material, it will be subject to more opportunities of being used in other functional foods and make a contribution to integrated medicinal food development.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2016.11a
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• pp.202-202
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• 2016

API X-80강재의 수소유기균열(HIC)현상을 비파괴적으로 평가하는 장치를 구축하고 금상학적 평가를 수행하였다. 시편은 열간 압연된 API X-80강재이며 평균입도는 약 $1.76-1.99{\mu}m$ 이었다. 압연재의 금상학적 집합조직은 (110)극점은 ND방향에 평행, (100)극점은 TD방향으로 약 $30^{\circ}$, TD방향으로부터 RD방향으로 약 $45^{\circ}$ 기울어져 있으며, (211)면은 RD방향에 수직인 면으로부터 TD방향으로 약 $35^{\circ}$ 기울어져서 있었다. Pin-on-disk형 마모시험기를 이용한 상온 평균 마찰계수는 0.745였으며 마모손실은 0.0196 mm/min 이었다. 3축 제어 초음파 비파괴 검사 장비는 표면으로부터 약 3mm 깊이의 1 mm 크기의 모의 균열을 탐촉자가 10 mm 접근하면 검출이 가능하였다. HIC시험분위기(NACE-standard TM 0248)에 1일 이상 장입하면 초음파비파괴검사장비로 측정될 수 있는 마이크로미터크기의 균열을 측정할 수 있었다.

• Journal of the Korean Society of Groundwater Environment
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• v.7 no.3
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• pp.125-132
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• 2000

pH, EC and TDS are basic components in the investigation of groundwater quality, and are very important to the preliminary assessment of groundwater quality. These three chemical components investigated at the Youngsan and Sumjin river basins in 1998 suggest that the groundwater quality is generally good in these basins. Linear regression analysis shows that TDS versus EC has an linear correlation, but EC versus pH, and TDS versus pH have nearly no correlation. The relation of TDS and EC is 1.0 mg/1=1.52 $mu\textrm{S}$/cm, and it is the quality of natural water. In geostatistical analysis. three kinds of data are stationary random functions and they have exponential variograms. According to the isopleth maps of the groundwater quality, the groundwater quality of the Youngsan river basin is more contaminated than that of the Sumjin river basin. The isopleth maps of TDS and EC show very similar patterns because of the strong correlation between TDS and EC. The minimum and maximum values of the groundwater quality data are not reflected on the isopleth maps because kriging produces smooth distributions with minimum estimation variances.

• Korean journal of applied entomology
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• v.35 no.3
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• pp.260-265
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• 1996

A field colony of the two-spotted spider mite, Tetranychus urticae Koch, was selected with tetradifon for 4 mousing whole-plant residual method. This strain showed 371-fold resistance to tetradifon. The log dosehatchability lines of $F_{1}$ eggs(RS cross; Td5female$\times$Smale, and SR cross; Sfemale$\times$Td5male) were closer to the line of the resistant colony than to that of the susceptible. These differences could be due to cytoplasmic inheritance or maternal effect. The estimate of dominance index (D) for the $F_{1}$ eggs of RS cross was 0.998 and that for $F_{1}$ eggs of SR cross was 0.262. This indicates that tetradifon resistance is completely dominant in RS cross and incompletely dominant in SR cross. Td5 strain exhibited high levels of resistance to clofentezine, benzoximate, and chlorfencon, and no cross resistance to fenazaquin, pyridaben, flufenoxuron, tebufenpyrad, and fenothiocarb.

• Journal of IKEEE
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• v.23 no.2
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• pp.438-447
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• 2019

As the IoT-based hyper-connected society grows, public-key cryptosystem such as RSA is frequently used for encryption, authentication, and digital signature. Public-key cryptosystem use very large (safe) prime numbers to ensure security against malicious attacks. Even though the performance of the device has greatly improved, the generation of a large (safe)prime is time-consuming or memory-intensive. In this paper, we propose ET-MR and ET-MR-MR using Euler sieve so it runs faster while using less memory. We present a running time prediction model by probabilistic analysis and compare time and memory of our method with conventional methods. Experimental results show that the difference between the expected running time and the measured running time is less than 4%. In addition, the fastest running time of ET-MR is 36% faster than that of TD-MR, 8.5% faster than that of DT-MR and the fastest running time of ET-MR-MR is 65.3% faster than that of TD-MR-MR and similar to that of DT-MR-MR. When k=12,381, the memory usage of ET-MR is 2.7 times more than that of DT-MR but 98.5% less than that of TD-MR and when k=65,536, the memory usage of ET-MR-MR is 98.48% less than that of TD-MR-MR and 92.8% less than that of DT-MR-MR.

• KSBB Journal
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• v.26 no.1
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• pp.7-12
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• 2011

In order to perform an acute toxicity assessment of a new algicide, thiazolidinedione derivative (TD53) with enhanced solubility and lower toxicity to marine ecosystem, representative 3 organisms: plant plankton (Skeletonema costatum), animal plankton (Daphnia magna), fish (Paralichthys olivaceus) related in the food chain of marine ecosystem according to OECD standard methods were employed in the exposure experiment. The exposure assessment showed that $EC_50$ of S. costatum in 96-hour, $EC_50$ of D. magna in 48-hour and $LC_50$ of P. olivaceus in 72-hour for TD53 were $1.53\;{\mu}M$, $0.61\;{\mu}M$ and $2.14\;{\mu}M$ respectively. NOEC (No Observed Effect Concentration) and PNEC (Predicted No Effect Concentration) were calculated to be $0.25\;{\mu}M$ and 6.10 nM, respectively from $EC_50$ of most sensitive strain, D. magna. Comparing with the results of toxicity assessment previously performed by using Ulva pertusa Kjellman accepted as an ISO standard method, the values of PNEC showed 3.7 times lower toxicity in case of this study employing 3 organisms, indicating that if the organisms which are more representative and sensitive in marine ecosystem are further investigated, more accurately and validly predicted toxicity of TD53 could be applied in field.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2951-2957
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• 2015

The development of worldwide harmful algal blooms(HAB) is a serious problem for public health and fisheries industries. To evaluate the algicidal impact on the HAB species, algicide thiazolidinedione derivative (TD49) and yellow clay were examined, which is focus on assess the algicidal effects and inhibition to photosynthesis of HAB species. To obtain the detailed information, we analyzed the viability of target species related to activity Chl. a, photosynthetic efficiency($F_v/F_m$), and electron transport rate(ETR). Culture experiment was conducted to evaluate the algicidal effects of three harmful species(raphidophyceae Heterosigma akashiwo, Chattonella marina, and dinophyceae Heterocapsa circularisquama) and one non-harmful species (cryptophyceae Rhodomonas salina). Our experiments revealed that three HAB species were easily destroyed of the cell walls after TD49 dosing. Also, they had significantly reducing values of active Chl. a, $F_v/F_m$, and ETR, due to the damage of photosystem II by inter-cellular disturbance. As a result, the algicidal effect(%) for the three HABs were as follows, in the order of greatest to the least: H. circularisquama> C. marina> H. akashiwo. However, the algicidal effect for yellow clay remained to be <30% (p>0.01), implying that it may not have damaged the photosystem II. On the other hand, non-HAB R. salina was promoted at both TD49 and yellow clay treatments. Our results demonstrated that the TD49 is a good agent for the control of HABs H. akashiwo, C. marina, and H. circularisquama, whereas the yellow clay would not be suitable for the field application based on our experimental results.

• Current Optics and Photonics
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• v.8 no.3
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• pp.282-299
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• 2024

Target detection (TD) is a research hotspot in the field of hyperspectral imaging (HSI). Traditional TD methods often mine targets from HSIs under a single imaging condition, without considering the influence of imaging conditions. In fact, the spectra of ground objects in HSIs are uncertain and affected by the imaging conditions (weather, atmospheric, light, time, and other angle conditions including zenith angle). Hyperspectral data changes under different imaging conditions. Therefore, the detection result for a single imaging condition cannot accurately reflect the effectiveness of the detection method used. It is necessary to analyze the performance of various detection methods under different imaging conditions, to find a more applicable detection method. In this paper, we study the performance of TD methods under various land-based imaging conditions. We first summarize classical TD methods and evaluation methods. Then, the detection effects under various imaging conditions are analyzed. Finally, the concepts of the stability coefficient (SC) and effective area under the curve (EAUC) are proposed to comprehensively evaluate the applicability of detection methods under land-based imaging conditions, in terms of both detection accuracy and stability. This is conducive to our selection of detection methods with better applicability in land-based contexts, to improve detection accuracy and stability.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.77-85
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• 2022

The Td05 and Sgc8c, DNA-based aptamers, are well-known to target internalized surface markers (IGHM and PTK7) of Burkitt's lymphoma and acute lymphoblastic leukemia (ALL). Thus, Td05 and Sgc8c labeled with metallic radioisotope ⁶⁴Cu can be evaluated as potential diagnostic PET imaging agents. In this study, we modified the carbon chain length of the last adenosine of aptamer (n = 3, 6, 12) to increase tumor cell uptake and select the best candidate among six types of aptamer analogues and one adenosine of aptamer. After labeling of ⁶⁴Cu, [⁶⁴Cu]Cu-DOTA-aptamer analogues were evaluated in vitro studies (serum stability, Log P values, cell uptake, biodistribution). Then, we evaluate in vivo PET imaging study for two candidates (⁶⁴Cu-DOTA-C12-Sgc8c, ⁶⁴Cu-DOTA-C6-Td05). PET images clearly visualize tumors at 24 h post-injection rather than at an early time point and the tumor-to-background ratio also increases at the delay time point. ⁶⁴Cu-DOTA-C12-Sgc8c and ⁶⁴Cu-DOTA-C6-Td05 could be used as potential radiotracers for lymphoma.

• Coupled systems mechanics
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• v.7 no.3
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• pp.353-371
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• 2018

The Wavenumber or more accurately Wavenumber-FD approach was initially introduced for two-dimensional dynamic analysis of concrete gravity dam-reservoir systems. The technique was formulated in the context of pure finite element programming in frequency domain. Later on, a variation of the method was proposed which was referred to as Wavenumber-TD approach suitable for time domain type of analysis. Recently, it is also shown that Wavenumber-FD approach may be applied for three-dimensional dynamic analysis of concrete arch dam-reservoir systems. In the present study, application of its variation (i.e., Wavenumber-TD approach) is investigated for three-dimensional problems. The method is initially described. Subsequently, the response of idealized Morrow Point arch dam-reservoir system is obtained by this method and its special cases (i.e., two other well-known absorbing conditions) for time harmonic excitation in stream direction. All results for various considered cases are compared against the exact response for models with different values of normalized reservoir length and reservoir base/sidewalls absorptive conditions.