• Title/Summary/Keyword: TD

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Proposal and Analysis of Primality and Safe Primality test using Sieve of Euler (오일러체를 적용한 소수와 안전소수의 생성법 제안과 분석)

  • Jo, Hosung;Lee, Jiho;Park, Heejin
    • Journal of IKEEE
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    • v.23 no.2
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    • pp.438-447
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    • 2019
  • As the IoT-based hyper-connected society grows, public-key cryptosystem such as RSA is frequently used for encryption, authentication, and digital signature. Public-key cryptosystem use very large (safe) prime numbers to ensure security against malicious attacks. Even though the performance of the device has greatly improved, the generation of a large (safe)prime is time-consuming or memory-intensive. In this paper, we propose ET-MR and ET-MR-MR using Euler sieve so it runs faster while using less memory. We present a running time prediction model by probabilistic analysis and compare time and memory of our method with conventional methods. Experimental results show that the difference between the expected running time and the measured running time is less than 4%. In addition, the fastest running time of ET-MR is 36% faster than that of TD-MR, 8.5% faster than that of DT-MR and the fastest running time of ET-MR-MR is 65.3% faster than that of TD-MR-MR and similar to that of DT-MR-MR. When k=12,381, the memory usage of ET-MR is 2.7 times more than that of DT-MR but 98.5% less than that of TD-MR and when k=65,536, the memory usage of ET-MR-MR is 98.48% less than that of TD-MR-MR and 92.8% less than that of DT-MR-MR.

Sensitivity Analysis of dVm/dtMax_repol to Ion Channel Conductance for Prediction of Torsades de Pointes Risk (다형 심실빈맥의 예측을 위한 dVm/dtMax_repol의 이온채널 전도도에 대한 민감도 분석)

  • Jeong, Da Un;Yoo, Yedam;Marcellinus, Aroli;Lim, Ki Moo
    • Journal of Biomedical Engineering Research
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    • v.43 no.5
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    • pp.331-340
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    • 2022
  • Early afterdepolarization (EAD), a significant cause of fatal ventricular arrhythmias including Torsade de Pointes (TdP) in long QT syndromes, is a depolarizing afterpotential at the plateau or repolarization phase in action potential (AP) profile early before completing one pace. AP duration prolongation is related to EAD but is not necessarily accounted for EAD. Several computational studies suggested EAD can form from an abnormality in the late plateau and/or repolarization phase of AP shape. In this sense, we hypothesized the slope during repolarization has the characteristics to predict TdP risk, mainly focusing on the maximum slope during repolarization (dVm/dtmax_repol). This study aimed to predict the sensitivity of dVm/dtmax_repol to ion channel conductances as a TdP risk metric through a population simulation considering multiple effects of simultaneous reduction in six ion channel conductances of gNaL, gKr, gKs, gto, gK1, and gCaL. Additionally, we verified the availability of dVm/dtmax_repol for TdP risk prediction through the correlation analysis with qNet, the representative TdP metric. We performed the population simulations based on the methodology of Gemmel et al. using the human ventricular myocyte model of Dutta et al. Among the sixion channel conductances, dVm/dtmax_repol and qNet responded most sensitively to the change in gKr, followed by gNaL. Furthermore, dVm/dtmax_repol showed a statistically significant high negative correlation with qNet. The dVm/dtmax_repol values were significantly different according to three TdP risk levels of high, intermediate, and low by qNet (p<0.001). In conclusion, we suggested dVm/dtmax_repol as a new biomarker metric for TdP risk assessment.

The difference of photosynthetic efficiency and electron transport rate by control of the red tide organism using algicidal substance and yellow clay (살조물질과 황토를 이용한 적조생물 제어에 따른광합성 효율 및 전자전달율의 차이)

  • Son, Moonho;Baek, Seung Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2951-2957
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    • 2015
  • The development of worldwide harmful algal blooms(HAB) is a serious problem for public health and fisheries industries. To evaluate the algicidal impact on the HAB species, algicide thiazolidinedione derivative (TD49) and yellow clay were examined, which is focus on assess the algicidal effects and inhibition to photosynthesis of HAB species. To obtain the detailed information, we analyzed the viability of target species related to activity Chl. a, photosynthetic efficiency($F_v/F_m$), and electron transport rate(ETR). Culture experiment was conducted to evaluate the algicidal effects of three harmful species(raphidophyceae Heterosigma akashiwo, Chattonella marina, and dinophyceae Heterocapsa circularisquama) and one non-harmful species (cryptophyceae Rhodomonas salina). Our experiments revealed that three HAB species were easily destroyed of the cell walls after TD49 dosing. Also, they had significantly reducing values of active Chl. a, $F_v/F_m$, and ETR, due to the damage of photosystem II by inter-cellular disturbance. As a result, the algicidal effect(%) for the three HABs were as follows, in the order of greatest to the least: H. circularisquama> C. marina> H. akashiwo. However, the algicidal effect for yellow clay remained to be <30% (p>0.01), implying that it may not have damaged the photosystem II. On the other hand, non-HAB R. salina was promoted at both TD49 and yellow clay treatments. Our results demonstrated that the TD49 is a good agent for the control of HABs H. akashiwo, C. marina, and H. circularisquama, whereas the yellow clay would not be suitable for the field application based on our experimental results.

Emotion Recognition in Children With Autism Spectrum Disorder: A Comparison of Musical and Visual Cues (음악 단서와 시각 단서 조건에 따른 학령기 자폐스펙트럼장애 아동과 일반아동의 정서 인식 비교)

  • Yoon, Yea-Un
    • Journal of Music and Human Behavior
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    • v.19 no.1
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    • pp.1-20
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    • 2022
  • The purpose of this study was to evaluate how accurately children with autism spectrum disorder (ASD; n = 9) recognized four basic emotions (i.e., happiness, sadness, anger, and fear) following musical or visual cues. Their performance was compared to that of typically developing children (TD; n = 14). All of the participants were between the ages of 7 and 13 years. Four musical cues and four visual cues for each emotion were presented to evaluate the participants' ability to recognize the four basic emotions. The results indicated that there were significant differences between the two groups between the musical and visual cues. In particular, the ASD group demonstrated significantly less accurate recognition of the four emotions compared to the TD group. However, the emotion recognition of both groups was more accurate following the musical cues compared to the visual cues. Finally, for both groups, their greatest recognition accuracy was for happiness following the musical cues. In terms of the visual cues, the ASD group exhibited the greatest recognition accuracy for anger. This initial study support that musical cues can facilitate emotion recognition in children with ASD. Further research is needed to improve our understanding of the mechanisms involved in emotion recognition and the role of sensory cues play in emotion recognition for children with ASD.

Efficacy of the pocket-creation method with a traction device in endoscopic submucosal dissection for residual or recurrent colorectal lesions

  • Daisuke Ide;Tomohiko Richard Ohya;Mitsuaki Ishioka;Yuri Enomoto;Eisuke Nakao;Yuki Mitsuyoshi;Junki Tokura;Keigo Suzuki;Seiichi Yakabi;Chihiro Yasue;Akiko Chino;Masahiro Igarashi;Akio Nakashima;Masayuki Saruta;Shoichi Saito;Junko Fujisaki
    • Clinical Endoscopy
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    • v.55 no.5
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    • pp.655-664
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    • 2022
  • Background/Aims: Endoscopic submucosal dissection (ESD) for residual or recurrent colorectal lesions after incomplete resection is challenging because of severe fibrosis. This study aimed to compare the efficacy of the pocket-creation method (PCM) with a traction device (TD) with that of conventional ESD for residual or recurrent colorectal lesions. Methods: We retrospectively studied 72 patients with residual or recurrent colorectal lesions resected using ESD. Overall, 31 and 41 lesions were resected using PCM with TD and conventional ESD methods, respectively. We compared patient background and treatment outcomes between the PCM with TD and conventional ESD groups, respectively. The primary endpoints were en bloc resection and R0 resection rates. The secondary endpoints were the dissection speed and incidence of adverse events. Results: En bloc resection was feasible in all cases with PCM with TD, but failed in 22% of cases of conventional ESD. The R0 resection rates for PCM with TD and conventional ESD were 97% and 66%, respectively. Dissection was significantly faster in the PCM with TD group (13.0 vs. 7.9 mm2/min). Perforation and postoperative bleeding were observed in one patient in each group. Conclusions: PCM with TD is an effective method for treating residual or recurrent colorectal lesions after incomplete resection.

A Study on the electron energy diffusion function of the sulphur hexaflouride ($ SF_6$가스의 전자에너지 분포함수에 관한 연구)

  • 김상남;하성철
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.13 no.2
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    • pp.95-101
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    • 1999
  • The electron energy distributions function were analysed in sulIitur hexaflowide at E/N : 500~800(Td) for a case of non-equilibrium region in the nran electron energy. This papa- describes the electron transport characteristics in $ SF_6$ gas calculated for range of E/N values from 150~800(Td) by the Monte Carlo simulation and Boltzmann equation Irethod using a set of electron collision cross sectioos determined by the authors and the values of electron swarm parameters. The results gained that the value of an electron swarm parameter such as the electron drift velocity, the electron ionization or attachment coefficients, longitudinal and transverse diffusion coefficients agree with the experimental and theoretical for a range of E/N. The properties of electron avalanches in an electron energy non-equilibrium region.region.

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A Study on Developing a Teardrop LED Lighting Fixture and Economic Analysis at Industrial Clean Rooms (산업용 클린룸에서의 Teardrop LED 등기구 개발 및 경제성 분석에 관한 연구)

  • Lhee, Sang Choon;Choi, Yeo Jin;Choi, Young Joon
    • KIEAE Journal
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    • v.13 no.4
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    • pp.63-68
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    • 2013
  • On the electricity consumption in Korea, the lighting sector takes about 17% of annual total electricity consumptions. In the midst of higher interests on energy conservation measures, design and choice of energy-saving lighting fixtures have been more important. With growth of technology-intensive industries like advanced material, semiconductor, and biotechnology from the 1980s, needs for clean room and thus illumination at clean rooms have been increased. In this paper, development, specification, and features of a Teardrop LED(hereinafter TD LED) lighting fixture as replacement of Teardrop florescent lighting one that has been popularly installed at clean rooms were presented. Also we performed the economic analysis of return on investment(ROI) about energy savings by the installation of the TD LED lighting fixture at a new-built clean room. The economic analysis showed that the new-developed TD LED lighting fixture would be able to withdraw the initial installation cost within 4 years. Lastly, improvement directions and development plans of the next TD LED lighting fixture for wider applications at clean rooms were described.

Physiological Activity in Doenjang Added with Various Mushrooms (버섯첨가된장의 생리활성 작용)

  • 이수진;이경임;이숙희;박건영
    • Korean journal of food and cookery science
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    • v.20 no.4
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    • pp.365-370
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    • 2004
  • The study was carried out to evaluate the radical scavenging activity, and antimutagenic and anticancer effects in Korean soybean paste(doenjang) added with various mushrooms. Ganoderma lucidum doenjang(Gl-TD) showed significant inhibitory activity against the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, with an IC$\sub$50/ value of 245$\mu\textrm{g}$/$m\ell$. In contrast, the other doenjang varieties appeared to have weaker antioxidant activity. Four kinds of doenjang didn't have any antimutagenic activity against N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) by adding of 5mg/plate, but exhibited a strong inhibitory effect(55∼70%) against aflatoxin B$_1$(AFB$_1$). Especially Phellinus linteus doenjang(Pl-TD) inhibited more than 70% of the mutagenicity induced by AFB$_1$ in Salmonella typhimurium TA100. On the other hand, the mushroom doenjang varieties showed relatively weak activity toward MNNG in SOS chromotest, their inhibitory rate ranging from 23% to 33%. Methanol extracts of Gl-TD and Pl-TD inhibited by 91∼92% the growth of AGS gastric cancer cells in a concentration of 100$\mu\textrm{g}$/$m\ell$.

Online Reinforcement Learning to Search the Shortest Path in Maze Environments (미로 환경에서 최단 경로 탐색을 위한 실시간 강화 학습)

  • Kim, Byeong-Cheon;Kim, Sam-Geun;Yun, Byeong-Ju
    • The KIPS Transactions:PartB
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    • v.9B no.2
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    • pp.155-162
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    • 2002
  • Reinforcement learning is a learning method that uses trial-and-error to perform Learning by interacting with dynamic environments. It is classified into online reinforcement learning and delayed reinforcement learning. In this paper, we propose an online reinforcement learning system (ONRELS : Outline REinforcement Learning System). ONRELS updates the estimate-value about all the selectable (state, action) pairs before making state-transition at the current state. The ONRELS learns by interacting with the compressed environments through trial-and-error after it compresses the state space of the mage environments. Through experiments, we can see that ONRELS can search the shortest path faster than Q-learning using TD-ewor and $Q(\lambda{)}$-learning using $TD(\lambda{)}$ in the maze environments.