• 공업화학
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• 제34권3호
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• pp.318-325
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• 2023

The detection of antibiotics in treated wastewater is a global concern as it enters water bodies and causes the development of antibiotic resistance genes in humans and marine life. The study specifically aims to explore the potential of ferrate (VI) in eliminating tetracycline (TCL). The degradation of TCL is optimized with parametric studies, viz., the effect of pH and concentration, which provide insights into TCL elimination. The increase in pH (from 7.0 to 10.0) favors the percentage removal of TCL; however, the increase in TCL concentrations from 0.02 to 0.3 mmol/L caused a decrease in percentage TCL removal from 97.4 to 29.1%, respectively, at pH 10.0. The time-dependent elimination of TCL using ferrate (VI) followed pseudosecond-order rate kinetics, and an apparent rate constant (kapp) was found at 1978.8 L² /mol² /min. Coexisting ions, i.e., NaNO₃, Na₂HPO₄, NaCl, and oxalic acid, negligibly affect the oxidation of TCL by ferrate (VI). However, EDTA and glycine significantly inhibited the elimination of TCL using ferrate (VI). The mineralization of TCL using ferrate (VI) was favored at higher pH, and it increased from 18.57 to 32.52% when the solution pH increased from pH 7.0 to 10.0. Additionally, the real water samples containing a relatively high level of inorganic carbon spiked with TCL revealed that ferrate (VI) performance in the removal of TCL was unaffected, which further inferred the potential of ferrate (VI) in real implications.

• Archives of Plastic Surgery
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• 제42권3호
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• pp.327-333
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• 2015

Background An anatomical analysis of the transverse carpal ligament (TCL) and the surrounding structures might help in identifying effective measures to minimize complications. Here, we present a surgical technique based on an anatomical study that was successfully applied in clinical settings. Methods Using 13 hands from 8 formalin-fixed cadavers, we measured the TCL length and thickness, correlation between the distal wrist crease and the proximal end of the TCL, and distance between the distal end of the TCL and the palmar arch; the TCL cross sections and the thickest parts were also examined. Clinically, fasciotomy was performed on the relevant parts of 15 hands from 13 patients by making a minimally invasive incision on the distal wrist crease. Postoperatively, a two-point discrimination check was conducted in which the sensations of the first, second, and third fingertips and the palmar cutaneous branch injuries were monitored (average duration, 7 months). Results In the 13 cadaveric hands, the distal wrist crease and the proximal end of the TCL were placed in the same location. The average length of the TCL and the distance from the distal TCL to the superficial palmar arch were $35.30{\pm}2.59mm$ and $9.50{\pm}2.13mm$, respectively. The thickest part of the TCL was a region 25 mm distal to the distal wrist crease (average thickness, $4.00{\pm}0.57mm$). The 13 surgeries performed in the clinical settings yielded satisfactory results. Conclusions This peri-TCL anatomical study confirmed the safety of fasciotomy with a minimally invasive incision of the distal wrist crease. The clinical application of the technique indicated that the minimally invasive incision of the distal wrist crease was efficacious in the treatment of the carpal tunnel syndrome.

• 한국통신학회논문지
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• 제19권10호
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• pp.1965-1972
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• 1994

ISDN 전화기는 송화자 에코에 관한 적절한 규정이 필요하며, 이는 ISDN 전화기의 송화 및 수화음량정격 및 단말 결합손실에 의해 좌우된다. 따라서, 전화기의 송화 및 수화음량정격이 규정될 경우, 에코가 없는 전화통화를 할 수 있는 단말 결합손실의 규정이 필요하며, 실질적으로 이에 대한 규정은 가중 단말 결합손실 (weighted terminal coupling loss ; $TCL_w$)과 에코 안정손실(stability loss)로 분류되어 규정될 수 있다. 본 연구에서는 전화 사용자의 에코 지각정도에 근거하여 단말 결합손실을 규정하기 위하여, 에코에 관한 오피니언 평가결과의 에코와 가입자 오피니언의 상관과 ISDN 전화기의 측정실험을 토대로 ISDN 전화기의 종합음량정격을 10dB로 정규화하였을 경우에는 적어도 40dB이상의 가중 단말 결합손실과 10dB이상의 안정손실을 국내기준으로 제안하였다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2010년도 추계학술발표대회
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• pp.1635-1637
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• 2010

Simulation tools help creating a low cost and efficient development of embedded system. SID is an open source simulator software that consists library of components for modelling hardware and software components. A component can be written in C/C++ and Tcl/Tk. Currently, the SID simulation toolkit only provides support for C++ and Tcl/Tk. Tcl/Tk is used to write GUI-based components. However, we have observed that Tcl/Tk components cause slow simulation response because Tcl/Tk is a script language. It is not proper for developing the cutting-edge products with rich graphics. Therefore, in this paper, we suggest Java to a new language for GUI components in SID by developing a bridge module for SID to interworking with Java components.

• The Korean Journal of Physiology and Pharmacology
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• 제23권6호
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• pp.449-458
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• 2019

Retinoblastoma (Rb) is one of the most common eye malignancies occur in childhood. The crucial roles of non-coding RNAs, particularly long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), have been widely reported in Rb progression. In the present study, we found the expression of lncRNA T-cell leukemia/lymphoma 6 (TCL6) was significantly downregulated in Rb tissues and cell lines. Knockdown of lncRNA TCL6 promoted cell proliferation while reduced cell apoptosis in Rb cells. Moreover, lncRNA TCL6 serves as a sponge for miR-21, a previously-reported oncogenic miRNA in Rb, by direct targeting to negatively regulated miR-21 expression, therefore modulating Rb proliferation through miR-21. TCL6 overexpression inhibited Rb cell proliferation while miR-21 overexpression exerted an opposing effect; the effect of TCL6 overexpression was partially attenuated by miR-21 overexpression. PTEN/PI3K/AKT signaling pathway was involved in lncRNA TCL6/miR-21 axis modulating Rb cell proliferation. Taken together, lncRNA TCL6 serves as a tumor suppressor by acting as a sponge for miR-21 to counteract miR-21-mediated PTEN repression.

• Journal of Electrical Engineering and Technology
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• 제10권3호
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• pp.755-765
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• 2015

A thermostatically controlled load (TCL) can be one of the most appropriate resources for demand response (DR) in a smart grid environment. DR capability can be effectively implemented in a TCL with various intelligent control methods. However, because traditional on-off control is still a commonly used method in a TCL, it is useful to develop a method for adding DR capability to the TCL with an existing on-off controller. As a specific realization of supervisory control for implementing DR capability in the TCL, two methods are proposed - a method involving the changing of a set point and a method involving the paralleling of an identified system without delay. The proposed methods are analyzed through the simulations with an electric heater for different power consumption levels in the on-state. Considerable cost benefit can be achieved with the proposed methods when compared with the case without DR. In addition, the observations suggest that a medium power consumption level, instead of the maximum power, in the on-state should be used for consistently obtaining the cost benefit without severe temperature deviation from the specified temperature range for DR.

• Journal of Electrical Engineering and Technology
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• 제11권3호
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• pp.644-652
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• 2016

This paper presents an improved single-stage ac-dc LED-drive flyback converter using the transformer-coupled lossless (TCL) snubber. The proposed converter is derived from the integration of a full-bridge diode rectifier and a conventional flyback converter with a simple TCL snubber. The TCL snubber circuit is composed of only two diodes, a capacitor, and a transformer-coupled auxiliary winding. The TCL snubber limits the surge voltage of the switch and regenerates the energy stored in the leakage inductance of the transformer. Also, the switch of the proposed converter is turned on at a minimum voltage using a formed resonant circuit. Thus, the proposed converter achieves high efficiency. The proposed converter utilizes only one general power factor correction (PFC) control IC as its controller and performs both PFC and output power regulation, simultaneously. Therefore, the proposed converter provides a simple structure and an economic implementation and achieves a high power factor without the need for any separate PFC circuit. In this paper, the operational principle of the proposed converter is explained in detail and the design guideline of the proposed converter is briefly shown. Experimental results for a 40-W prototype are shown to validate the performance of the proposed converter.

• Journal of Information Processing Systems
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• 제8권1호
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• pp.101-118
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• 2012

Embedded products are becoming richer in features. Simulation tools facilitate low-costs and the efficient development of embedded systems. SID is an open source simulation software that includes a library of components for modeling hardware and software components. SID components were originally written using C/C++ and Tcl/Tk. Tcl/Tk has mainly been used for GUI simulation in the SID system. However, Tcl/Tk components are hampered by low performance, and GUI development using Tcl/Tk also has poor flexibility. Therefore, it would be desirable to use a more advanced programming language, such as Java, to provide simulations of cutting-edge products with rich graphics. Here, we describe the development of the Java Bridge Module as a middleware that will enable the use of Java Components in SID. We also extended the low-level SID API to Java. In addition, we have added classes that contain default implementations of the API. These classes are intended to ensure the compatibility and simplicity of SID components in Java.

• 대한수의학회지
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• 제54권4호
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• pp.245-252
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• 2014

This study was investigated the change of concentration and toxicity of thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION) on tissues of Sprague-Dawley rats. TCL-SPION at the dose of 15 mg/kg body weight was intravenously injected into the tail vein of the male Sprague-Dawley rats. The fate of TCL-SPION in serum, urine and tissues was observed during 28 days. Serum iron level was maximal at 0.25 h post-injection and gradually declined thereafter. In addition, the sinusoids of liver and the red pulp area of spleen were mainly accumulated iron from 0.5 h to 28-day post-injection. In kidney, iron deposition was detected in the tubular area until 0.5 h after injection. Malondialdehyde concentration in the liver slightly increased with time and was not different with that at zero time. In the liver and spleen, TNF-${\alpha}$ and IL-6 levels of TS treated with TCL-SPION were not different with those of the control during the experimental period. From the results, TCL-SPION could stay fairly long-time in certain tissues after intravenous injection without toxicity. The results indicated that TCL-SPION might be useful and safe as a contrast for the diagnosis of cancer or a carrier of therapeutic reagents to treat diseases.

• 한국철도학회논문집
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• 제17권5호
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• pp.355-364
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• 2014

연속철근 콘크리트궤도에서는 온도 및 수분 변화에 따른 구속응력에 의해 횡균열이 발생한다. 이러한 균열은 연속철근 콘크리트궤도의 거동과 장기 공용성에 상당한 영향을 미치는 것으로 알려져 있다. 이와 같은 횡균열이 콘크리트궤도의 거동에 미치는 영향을 분석하고 균열 관리 기준을 보다 합리적으로 결정하기 위해, 이 연구에서는 연속철근 콘크리트궤도에 열차하중이 작용할 때 균열이 발생한 궤도 슬래브(TCL)와 기층(HSB)의 응력 분포를 3차원 유한요소해석 모델을 이용하여 예측하였다. 해석 결과에 따르면 균열 깊이가 증가할 경우 TCL의 휨응력과 TCL-HSB 경계부 수직응력이 증가하고, 균열이 슬래브를 관통할 경우 TCL 균열부에서 철근 주변에 국부적으로 수직 응력이 커져 장기적으로 펀치아웃 발생 가능성이 커질 수 있다. 반면 균열폭과 간격의 영향은 균열 깊이에 비해 크지 않은 것으로 나타났다. 따라서 균열폭과 간격만 관리하는 것보다는 균열 깊이를 동시에 관리할 필요가 있다. 또한 HSB 수축 줄눈의 위치를 침목 사이에 위치하도록 하는 것이 장기 공용성 확보에 더 유리하다.