• The Korean Journal of Nuclear Medicine
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• v.20 no.1
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• pp.17-24
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• 1986

Authors enumerate various malignant and benign cases which showed soft tissue uptake of $^{99m}Tc-MDP$. We hope it might be a help in understanding and interpreting bone scans. Among 10,361 $^{99m}Tc-MDP$ bone scans underwent from April, 1981 to March, 1986, 344 (3.3%) showed abnormal soft tissue uptake, which included 126 malignancies, 5 benign tumors, and 153 nontumorous diseases. Neuroblastoma(23.3%) and malignant fibrous histiocytoma(22.2%) showed highest positive uptake rate among various malignancies. We also illustrated typical cases according to possible mechanisms.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.6
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• pp.1021-1032
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• 1997

Satellite-tracked drifters deployed in the East Sea since 1991 are used to study the Tsushima Current (TC). It is found that the TC is a steady current with a mean speed of 10 cm/s before it enters the East Sea. Only during the summer, the TC flows along Honshu Island with a mean speed of $30\~40\;cm/s$ and then exits through the Tsugaru Strait. In fall and winter, the TC does not follow the coast along Honshu Island but it enters into the interior of the East Sea before it reaches the Tsugaru Strait. The water that passes the West Channel of the Korea Strait mostly comes from the western East China Sea and spreads into the interior of the East Sea. It also forms the large eddies in the southern East Sea. The outflow through the Tsugaru Strait comes from the interior of the East Sea in all seasons except summer. The mean speed of the Tsugaru Strait outflow is about 60 cm/s. The largest current variability is found in the eastern central area of the East Sea, south of sub-polar front.

• Bulletin of the Korean Chemical Society
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• v.34 no.4
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• pp.1120-1126
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• 2013

The syndecan family consists of four transmembrane heparan sulfate proteoglycans present in most cell types and each syndecan shares a common structure containing a heparan sulfate modified extracellular domain, a single transmembrane domain and a C-terminal cytoplasmic domain. To get a better understanding of the mechanism and function of syndecan-4 which is one of the syndecan family, it is crucial to investigate its three-dimensional structure. Unfortunately, it is difficult to prepare the peptide because it is membrane-bound protein that transverses the lipid bilayer of the cell membrane. Here, we optimize the expression, purification, and characterization of transmembrane, cytoplasmic and short extracellular domains of syndecan4 (syndecan-4 eTC). Syndecan-4 eTC was successfully obtained with high purity and yield from the M9 medium. The structural information of syndecan-4 eTC was investigated by MALDI-TOF mass (MS) spectrometry, circular dichroism (CD) spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. It was confirmed that syndecan-4 eTC had an ${\alpha}$-helical multimeric structure like transmembrane domain of syndecan-4 (syndecan-4 TM) in membrane environments.

• Magazine of the Korean Society of Agricultural Engineers
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• v.39 no.3
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• pp.108-114
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• 1997

Concrete is said to have a high degree of extensibility when it is subjected to large deformations without cracking. The cracking behavior of concrete in the field may even be more complex. For example, in mass concrete compressive stresses are developed during the very early period when temperatures are rising, and the tensile stresses do not develop until at a later age when the temperature begins to decline. Actual cracking and failure depend on the combination of factors and indeed it is rarely that a single adverse factor is responsible for cracking of concrete. The importance of cracking and the minimum width at which a crack is considered significant depend on the conditions of exposure of the concrete. The ultrasonic pulse measurements can be used to detect the development of cracks in structures such as dams, and to check deterioration due to frost or chemical action. An estimate of the depth of a crack visible at the surface can be obtained by measuring the transit times across the crack for two different arrangements of the transducers placed on the surface. In this paper, the concrete cracks that artificially introduced crack width is 1 and 2mm, crack depth is 2, 4, 6, 8cm were measured by Tc-To Method In consequence, the measured depth was increased with increase of measuring distance from concrete crack. The most reliable results were shown when the introduced crack width was 1mm, and the measuring distance was 10cm from concrete crack.

• Smart Structures and Systems
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• v.22 no.4
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• pp.383-397
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• 2018

Traditional base isolation systems focus on isolating the seismic response of a structure in the horizontal direction. However, in regions where the vertical earthquake excitation is significant (such as near-fault region), a traditional base-isolated building exhibits a significant vertical vibration. To eliminate this shortcoming, a rocking-isolated system named Telescopic Column (TC) is proposed in this paper. Detailed rocking and isolation mechanism of the TC system is presented. The seismic performance of the TC is compared with the traditional elastomeric bearing (EB) and friction pendulum (FP) base-isolated systems. A 4-storey reinforced concrete moment-resisting frame (RC-MRF) is selected as the reference superstructure. The seismic response of the reference superstructure in terms of column axial forces, base shears, floor accelerations, inter-storey drift ratios (IDR) and collapse margin ratios (CMRs) are evaluated using OpenSees. The results of the nonlinear dynamic analysis subjected to multi-directional earthquake excitations show that the superstructure equipped with the newly proposed TC is more resilient and exhibits a superior response with higher margin of safety against collapse when compared with the same superstructure with the traditional base-isolation (BI) system.

• Journal of the Ergonomics Society of Korea
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• v.30 no.1
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• pp.161-168
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• 2011

Objective: The aim of this study is to review the ISO(the International Organization for Standardization) standards recommendations on a human error tolerant control room design. Background: ISO TC(Technical Committee) 159 published a variety of international standards on design of mental and physical work, design of displays and controls, and workstation layout design. A proper edition of these standards can be a good resource for a human error tolerant control center design guidelines. Method: Recommendations of ISO TC 159 standards were grouped into arrangement of control suite, layout of control room, layout and dimensions of workstations, design of displays and controls, environmental design, alarm, automation, management system design, procedure and training. Results: It was found that some standards on the design of supervisory control and data acquisition(SCADA), alarm, automation, layout, workload management, and environment can be used for human error prevention guidelines in the control center design. Conclusion: ISO TC 159 standards were not sufficient to cover all the ergonomics area of control center design. Application: Designers can have technical aids from these ISO standards to improve ergonomic performance of their control center.

• The Korean Journal of Zoology
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• v.10 no.1
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• pp.1-9
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• 1967

본 실험은 4 일간의 성주기가 뚜렷한 성체인 golden hamster로부터 미성숙인 난자를 적출하여 화학적배양액내에서 그의 성숙을 유도시키고 성주기에 따른 미성숙 난자의 성렬율을 관찰하는 것을 주요 목적으로 하여 행하여졌다. 한 개의 난소로부터 5-6개의 미성숙 난자를 적출하여 5% bovine serum albumin이 섞인 TC Medium 199에 넣어서$CO_2$-incubator를 이용하여 6 시간내지 24시간 동안 37$^{\circ}C$를 유지해가며, 배양액이 직접 공기와접촉하는 것을 막기 위해 유동성인 paraffin oil로 배양액을 덮고서 배양을 완수했다. 실험의 결과를 다음과 같이 완수했다. 1. Hamster의 난자의 성숙분렬을 유발시키는데 가장 적합한 배양액은 BMOC, Eagle's Medium , Waymouth's Medium 그리고 TC Medium 199의 네가지 가운데 TC Medium199이었다. 즉 이 배양액을 이용했을 때 난자가 높은 성렬도를 보여주었다. 2. 5% bovine serum alumn을 TC Medium 199에 섞어주었을 때 미성숙 난자가 성순분렬을 유기하는 율이 가장 높았다. 3. 발정기에 있는 난소로부터 얻은 난자가 가장 현저하게 높은 율로 성숙분렬을 보여주었다. 반대로 발정후기의 난자는 배양 시작 후 단시간 내에 대부분이 퇴화하였으며 발정기에 가까워 갈수록 퇴화율이 줄어들었다. 이것은 노포가 성숙분렬을 억제하는 물질을 생성하리라고 여겨지고 있긴 \ulcorner만, 동시에 이 노포는 또 한편 난자의 배란뒤에까지도 생명력을 유지할수 있는 능력을 발정기에 이르기까지의 기간동안 난자에게 부여하며, 난자는 이 능력을 배란전까지 축적하게 되며 이 때문에 노포로부터 유리되어 나온 난자가 장기간 그 생명력을 유지해나가는 것이라고 추정된다. 4. Paraffin oil 로 공기를 차단하여서 배양한 난자나 혹은 watch glass를 이용하여 공기와 접촉시킨 난자에서나 모든 비슷한 율로 성숙분렬을 보여주었다. 이로 보아 조작이 까다로운 paraffin oil을 이용하는 방법보다는 손쉽게 배양할 수 있는 watch glass 의 방법이 오히려 유용하다고 할 수 있다.

• Annual Conference of KIPS
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• 2022.05a
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• pp.553-556
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• 2022

이상지질혈증의 발병에 대한 조기 진단 및 관리하는 것은 중요한 문제이다. 이상지질혈증의 진단은 혈액계측 정보 중에서 네 가지 LDL, HDL, TG, 그리고 TC를 이용하여 진단하며, 이상지질혈증 관리를 위해서는 LDL을 추정하는 것이 중요하다. 본 논문에서는 나이, 성별, 그리고 BMI와 같은 신체계측 정보를 학습하여 LDL-콜레스테롤을 예측하기 위한 준지도학습(Semi-supervised learning) 기반 기계학습 방법을 제안한다. 제안 방법은 얕은 학습(Shallow Learning)기반의 MLP(Multi-Layer Perceptron)을 이용하고, 이상지질혈증 진단인자간의 상관관계를 고려하여 신체계측 정보로 예측된 HDL, TG, 그리고 TC을 이용하여 일반적인 기계학습을 이용한 예측방법의 정확도를 개선한다. 즉, 제안방법은 신체계측 정보를 이용하여 혈액계측 정보의 LDL, HDL, TG, 그리고 TC을 각각 예측하고, 신체계측에 혈액계측의 예측 정보를 추가하여 학습한 준지도학습 기반 얕은 네트워크를 설계한다. 실험결과, HDL, TG, 그리고 TC의 혈액예측 정보를 이용한 준지도학습 기반 LDL 예측 정확도는 71.4%로 신체계측 정보만을 이용한 예측 방법의 67.0% 보다 약 4.4% 개선할 수 있음을 확인한다.

• Nuclear Engineering and Technology
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• v.55 no.1
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• pp.304-309
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• 2023

In the last decade, nuclear medicine appears to be a good choice of medicine. ⁵⁸Co, ⁹⁹Mo, ⁹⁹Tc, ⁹⁹Re, ¹³³Xe and ¹⁸⁶Re are very important radionuclides for nuclear medicine. In this study, the excitation functions of ⁵⁸Ni (n, p) ⁵⁸Co, ⁹⁹Tc (n, p) ⁹⁹Mo, ⁹⁹Ru (n, p) ⁹⁹Tc, ¹³¹Xe (n, p) ¹³¹I, ¹³³Cs (n, p) ¹³³Xe and ¹⁸⁶Os (n, p) ¹⁸⁶Re nuclear reactions were calculated at neutron energies between 1 and 20 MeV using TALYS 1.95 and EMPIRE 3.2 nuclear codes. Furthermore, the cross sections were calculated with the empirical formula derived in our past study at 14-15 MeV. The obtained results were compared with the measured values in EXFOR library, and with the evaluated data of (JENDL-4.0/HE, JEFF-3.3, TENDL-2019, ENDF/B-VIII.0, IRDFF-II, JENDL/ImPACT-18). The results are in good agreement with those of the evaluated data libraries and experimental results and indicates that these radioisotopes can be produced by smaller cyclotrons.

• The Korean Journal of Nuclear Medicine
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• v.33 no.6
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• pp.484-492
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• 1999

Purpose: This study was to evaluate the clinical usefulness of $^{99m}Tc$-MDP bone scintigraphy for assessing vascular ingrowth into the ocular implants after enucleation or evisceration. Materials and Methods: Twenty-four patients (M:F=7:17, mean age: 36 years), who buried a coralline hydroxyapatite after uncomplicated enucleation or evisceration surgery were studied. Dynamic and static scintigraphy on the orbit fossa were obtained after injection of 740 MBq $^{99m}Tc$-MDP to evaluate the status of vascularization. The study was performed from the 3 to 33 weeks after surgery. According to the visual analysis, activity greater than nasal bridge was graded as 4, equal to the nasal bridge as 3, less than nasal bridge but greater than normal orbit as 2, greater than normal orbit but less than grade 2 as 1. Uptake ratio was also calculated by measuring the implants activity (H) and contralateral orbit activity (N). Grading score and uptake ratio were compared with clinical outcome of vascularization. Additionally, we also analyzed the vascularization status as time lapse between primary surgery and scintigraphic study and surgical methods. Results: Twenty-one patients who had bone scintigraphy at 11 weeks after surgery showed increased uptake above grade 2 and greater H/N ratio than 1.16. Of these, 19 patients who had drilling surgery for permanent peg application showed adequate bleeding during the procedure. The activity grade and uptake ratio were inversely correlated with vascular ingrowth. Higher than grade 2 or greater than 1.56 in H/N ratio seemed to be an indicator for better prognosis. Accomplishment of vascularization was not affected by the surgical way such as enucleation or evisceration. Conclusion: $^{99m}Tc$-MDP bone scintigraphy can be a useful method to evaluate the vascularized status of implants. Adequate time for $^{99m}Tc$-MDP bone scintigraphy may be 11-20 weeks after enucleation or evisceration.