• 한국축산식품학회지
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• 제20권1호
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• pp.1-7
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• 2000

The influence of the ditary containing boiled eggs on the plasma cholesterol level and antithrombotic activity in rats was studied. Rats were fed basal diet(0% boiled eggs) as a control group or diets containing 25% and 50% boiled eggs or a mixed diet with 95% boiled eggs plus 5% $\alpha$-cellulose powder as a experimental groups for 30 days. The bleeding time and whole blood clotting time were significantly(P<0.05) increased by feeding diet containing 25% boiled eggs compared to groups of basal diet, 50% or 95% boiled eggs diets. The plasma clotting time was high in group of 25% boiled eggs diet. However, there were no difference in plasma clotting time among rats fed the dietary boiled eggs. The levels of plasma total cholesterol(TC) and low density plus very low density lipoprotein cholesterol(LDL, VLDL-C) were significantly(P<0.05) highest in group 95% boiled eggs diet compared to others. There were no differences in high density lipoprotein cholesterol(HDL-C) among rats fed the dietary boiled eggs. The levels of plasma TC, HDL-C, LDL$.$VLDL-C and the ratios of HDL-C/TC were not significant among the basal diet, 25% and 50% boiled eggs diets. These results suggest that the intakes of the dietary boiled eggs have the antithrombotic activity and plasma cholesterol lowering effect.

• 대한간호학회지
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• 제41권2호
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• pp.182-190
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• 2011

Purpose: This study was done to identify correlates and variables predicting daily activity among elders with Diabetes Mellitus (DM). Methods: Seventy-six elders registered in the Department of Endocrine Medicine at C university hospital participated in data collection. Data on daily activity and biochemical variables were collected via actigraph accelerator (Actical) and blood tests between September 2009 and July 2010. Data analysis was done using SPSS WIN 15.0 program and included one-way ANOVA, independent t-test, Pearson correlation coefficients, and stepwise multiple regression. Results: This study showed a positive correlation between daily activity and High Density Lipoprotein Cholesterol (HDL-C) and a negative correlation among Total Cholesterol (TC), Triglyceride (TG), and Low Density Lipoprotein Cholesterol (LDL-C). The variables predicting daily activity were frequency of exercise, HDL-C, and TC. These factors accounted for 40.0% of the variance of daily activity in elders with DM. Conclusion: The results indicate that it is necessary to improve daily activity to reduce Fasting Blood Glucose (FBG), TC, and TG in elders with DM.

• 대한물리의학회지
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• 제8권2호
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• pp.239-243
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• 2013

PURPOSE: The purpose of present study was to investigate effects of obesity, blood pressure and life style on lipid indices and blood pressure in men of age 40s. METHODS: One hundred forty five subjects in men of age 40s were participated in this study. All participants were taken physical examination, lifestyle survey and laboratory test. According to examination, participants were divided into two group in four categories ; obesity and normal group, hypertension and normal group, smokers and non-smokers, and drinkers and non-drinkers. The low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) were analyzed by independent t-test for comparison between two groups. RESULTS: The values of LDL, TC, SBP, DBP were higher and HDL was lower in obesity than in normal group (p<.05). The values of LDL, TC, SBP, DBP were higher in hypertension group than in normal group (p<.05). The values of TG was higher and HDL was lower in smokers than in non-smokers (p<.05). There's no significant differences between drinkers and non-drinkers (p>.05). CONCLUSION: It can be seen that obesity and blood pressure were more relative risk factors than smoking and alcohol indices in cardiovascular diseases.

• 한국산학기술학회논문지
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• 제13권9호
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• pp.3962-3972
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• 2012

고령기의 생활을 위협하는 obesity 여성고령자를 대상으로 sarcopenia 동반에 따른 CVD 위험의 가중성과 16주간의 운동중재가 CVD 위험인자에 미치는 변화를 알아보고자 한다. 또한, 이러한 운동효과를 검증하여 obesity 여성고령자에게 obesity와 sarcopenia에 대한 운동의 중요성을 부각시켜 삶의 질 향상에 도움을 주기 위한 연구이다. 비만 여성고령자를 sarcopenia 동반유무에 따라 sarcopenic obesity group(SOG)과 non-sarcopenic obesity group(NOG)으로 나누어 16주간, 주 3회, 50-60분간 복합운동 실시 후 심혈관질환 위험인자에 미치는 영향을 분석하여 다음과 같은 결론을 얻었다. 운동 전 두 그룹간 CVD 위험인자 비교에서는 비만 여성고령자에게 sarcopenia가 동반될 경우 CVD 위험이 가중되지 않았으며, sarcopenic obesity 여성고령자가 non-sarcopenic obesity 여성고령자보다 HDL-C는 높게, TG는 더 낮게 나타났다. 운동중재 후에는 혈청지질에서 sarcopenic obesity 여성고령자의 경우 TC, TG는 감소하였고, HDL-C, LDL-C은 차이가 없었다. non-sarcopenic obesity 여성고령자의 경우 TC, TG, LDL-C는 감소하였으며, HDL-C 증가하였다. 따라서, sarcopenia와 CVD 위험인자와의 낮은 관련성을 확인할 수 있었으며, sarcopenic obesity 여성고령자가 non-sarcopenic obesity 여성고령자에 비해 HDL-C, LDL-C, BP, right baPWV에서 운동효과가 더디다는 것을 발견할 수 있었다.

• 대한지역사회영양학회지
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• 제6권1호
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• pp.51-68
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• 2001

This investigation studied the relationship between Body Mass Index(BMI) and dietary intake, levels of serum lipid, lipoprotein(a) and plasminogen activator inhibitor-1(PAI-1) of 28.449 Korean adults(16.937 men, 11.542 women) from 1995 to 1999. The dietary assessment was conducted using 24-hour dietary records and food frequency questionnaires. During this five year study, the BMI normal-weight group, as a percentage of the annual test population, decreased from 68.0% to 60.2%, while the BMI overweight and obese groups collectively increased from 25.0% to 29.7%. The levels of serum total cholesterol (TC), LDL-cholesterol(LDL-C), Triacylglycerol(TG) and PAI-1 increased as the values of BMI increased, while the levels of HDL-cholesterol(HDL-C) and lipoprotein(a)(men only) appeared to decrease as values of BMI increased. The levels of daily energy intake also increased as values of BMI increased in both men and women. The obese group had significantly higher levels of carbohydrate, protein, fat(men only), and cholesterol intake than those of the normal-weight, underweight, and overweight groups. In men, BMI positively correlated with the levels of macronutrients and cholesterol intake(p＜0.001), % energy of protein, fat, and alcohol intake(p＜0.001), and the levels of serum TC, LDL-C, TG and PAI-1(p＜0.001), while BMI negatively correlated with % energy of carbohydrate intake, and the levels of Lp(a) and HDL-C(p＜0.001). In women, BMI negatively correlated with level of cholesterol(p＜0.01), fat(p＜0.001), alcohol intake(p＜0.05),% energy of fat (p＜0.001), % energy of alcohol intake and level of and HDL-C(p＜0.001). Subjects who had serum TC, LDL-C, HDL-C, and TG levels greater than the standard reference values(TC＞240mg/㎗, LDL-C＞130mg/㎗, HDL-C＞35, TG＞200mg/㎗) exhibited a higher intake of the three macronutrients, iron, calcium, meat, milk and fatty foods than those subjects who had serum lipid concentrations less-than-or-equal-to the standard reference values. Overall, there was positive correlation between the high risk factors of vascular disease variables, dietary intake, and BMI. Prevalence of hypertension and high blood sugar were increased as BMI increased, but the prevalence of hypertension is decreased as the year goes by. These findings showed that dietary intake, level of serum lipids and other vascular disease risk factors increased as BIM increased. Therefore, middle or upper class Korean adults who have high BMI should improve their eating habits. This involve reducing alcohol, animal fat, high carbohydrate foods, and overall food intake, and balancing intake in order to lower vascular disease risk factors, including obesity.

• Journal of Nutrition and Health
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• 제23권1호
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• pp.1-10
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• 1990

$\omega$-3계의 지방산의 함량이 많은 어유는 혈청 지질을 저하시키므로 동맥경화증의 위험을 감소시킨다고 보고되어 있다. 그러나, 어유의 효과가 식이중 지방함량이 낮은 수준에서더 현저한가에 대해서는 확실히 알려져 있지 않다. 본 연구는 식사중 지방 함량이 서양인보다 적고,CHD의 예견인자가 다른 한국인에게, 실험군에 따라 1일 9g, 12g 및 15g 의 어유를 1주간 투여한후 혈청 지질을 조사한 결과는 다음과 같다. 1) 혈청 TC함량은 어유 투여 후 및 투여 중단 1주째에 유의적인 감소(p<0.01)를 나타내었으며, 혈청 TG함량은 어유 투여 후에 유의적인 감소를 나타내었다. 2) 혈청 지단백질의 전기영동 결과, VLDL함량은 유의적인 변화를 나타내지 않았고, LDL은 투여중단 1주째에 세 군 모두에서 유의적인 감소(p<0,05)를 나타내었으며, HDL은 9g군에서만 유의적인 증가(p<0.05)를 나타내었다. 3) HDL-C함량은 12g군과 15g군에서 투여 중단 1주째 및 투여 중단 3주째에 유의적인 증가(p<0.05)를 나타내었다. LDL-C 함량은 투여 후 유의적인 감소(p<0.05)를 나타내었고, 투여 중단 1주째에 세 군 모두에서 유의적인 감소(p<0.001)를 나타내었다.

• 디지털융복합연구
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• 제18권10호
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• pp.509-516
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• 2020

본 연구는 12주간의 저항성운동 유형이 여성 노인의 근손상 지표 및 혈중지질에 미치는 영향을 규명하고자 하였다. 연구대상은 여성노인 30명을 통제집단 10명, 아쿠아로빅운동 집단 10명, 순환운동 집단 10명을 무선으로 배정한 후 주당 3회 1회 운동시 60분을 적용하여 각 집단별 운동을 12주간 실시하였다. Total Cholesterol(TC), Low Density Lipoprotein Cholesterol(LDL-C), High Density Lipoprotein Cholesterol(HDL-C)은 교호작용효과가 나타나지 않았으나, 체중과 체지방량은 교호작용효과가 나타났다. 체중, 체지방량, TC, LDL-C은 통제집단에 비해 수중운동과 순환운동 후 유의한 감소를 나타냈으며, HDL-C은 통제집단에 비해 수중운동과 순환운동 후 유의한 향상을 나타냈다. Triglyceride(TG), Creatine Phosphokinase(CPK), Lactate Dehydrogenase(LDH)는 유의한 차이를 나타내지 못하였다. 이를 통하여 수중운동과 순환운동은 여성노인에게 있어 체중 및 혈중지질 감소와 HDL-C의 증가에 있어 효율적인 운동이라 제시 할 수 있으며 여성노인에게 있어 근감소예방과 개선에 효과적인 운동으로 적용될 수 있을 것이라 사료된다.

• Advances in Traditional Medicine
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• 제8권3호
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• pp.311-315
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• 2008

The objective of the study was to investigate the antihyperlipidemic activity of alcoholic extract of Pongamia pinnata Linn. (PPAE) leaves in rats fed with high fat diet (HFD). PPAE was administered orally in the divided doses of 250 and 500 mg/kg/day for 30 days in HFD fed rats. Body weights were observed and the analysis of serum lipid profile was carried out on day 30. Marked decrease in the body weight, total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) whereas significant increase in the levels of high density lipoprotein (HDL) were observed after treatment with PPAE. However, PPAE in a dose of 250 mg/kg did not show significant (P < 0.05) increase in HDL levels. The PPAE also lowered TC: HDL-c and LDL: HDL-c ratios significantly suggesting it's antihyperlipidemic and cardioprotective potential. The present work reveals that PPAE at the dose of 500 mg/kg/day exhibited significant (P < 0.01) antihyperlipidemic effects.

• Journal of Nutrition and Health
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• 제46권4호
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• pp.324-331
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• 2013

We investigated dietary effects of green tea powder (GTP) on plasma lipids, platelet aggregation, hemolysis, plasma TBARS, and liver enzymes. Thirty one volunteer diving women living on Jeju island consumed 4 g green tea powder daily for a period of four weeks and data for the study subjects were analyzed on the basis of diagnostic criteria for blood pressure (BP)(${\geq}$ 140/90 mmHg), plasma total cholesterol (TC)(${\geq}$ 200 mg/dL), and triglyceride (TG)(${\geq}$ 150mg/dL). Subjects with high BP had significantly higher TC and TG than those with normal BP. Subjects with higher TC had higher TG, and those with higher TG had lower HDL cholesterol. Platelet aggregation in the initial slope was significantly higher in subjects with normal BP, normal TC, or normal TG than their counterparts in high BP, TC, and TG. HDL cholesterol after GTP intake increased only in subject groups with normal BP, normal TC, or normal TG, and plasma TG after GTP intake decreased only in groups with higher BP, higher TG, or higher TC. Plasma TC and TG in subjects with normal BP increased after GTP intake. GTP intake caused a decrease in the initial slope of platelet aggregation in all subject groups with little effect on maximum aggregation. Total bilirubin showed a significant increase and GOT increased in all subject groups after GTP intake. Beneficial effects of short term intake of green tea powder might differ depending on the subject conditions in terms of blood pressure, plasma lipids, and other cardiovascular conditions. However, with the hypolipidemic, antithrombotic, and antioxidant actions of its bioactive flavonoids, long term usage of GTP or brewed green tea may provide preventive effects against cardiovascular disease.

• 한국식품영양학회지
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• 제6권4호
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• pp.255-267
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• 1993

This study was performed to investigate the correlations among physical anthropometric measurement, diet intakes, physical fitness test, and serum lipids in eight sedentary women(control group), and twenty seven exercising women(aerobic groups), aged 35~45 years. The results of the study are as follows : 1) systolic blood pressure(SBP) and diastolic blood pressure(DBP) of aerobic groups were lower than serf entary. Pulse rate was decreased according to the length of aerobic periods. Muscular endurance and jump power of all subjects were stronger than standard range, and those of aerobic exercising groups were stronger than control group. Muscular power of the upper half of the body In all subjects were lower than standard range. 2) Daily calorie intakes of all subjects were in the ring: of recommended dietary allowances (RDA) for Koreans. But daily protein Intakes were higher than RDA. daily cholestrol intakes of all subjects were slightly less than 200~300 mg: which is normal consumption of Koreans. 3) There was a significant positive correlation between serum 7G and daily protein intakes. It was considered that excessive protein intake converted to serum 7G. There was not a significant correlation between serum TC and dietary TC. Therefore, dietary TC seemed to have not much effect on serum TC. Physical fitness was negatively related to serum TG, TC, LDL-C, but positively related to HDL-C, HDL-C /TC. It was found that the serum lipids could be changed better according to improving the physical fitness. There were significant positive correlations between SBP and serum TC, LDL-C. (According to this results), the higher SBP, the higher serum TC, LDL-C tended to be. There was a significant positive correlations between sit up and weightloss nth exercise r=0.7(p<0.001), push ups and weightless with exercise r=0.5(p<0.001). It was considered that muscle strength could be improved according to the weightloss. 4) The purpose of exercise in aerobic groups was rather promoting health than reducing body fatness. Most of al1 subjects (83.2%) drank caffeine-contained beverage therefore, we should concern about that absorption of Fe could be Interrupted and blood pressure could be elevated by caffeine.