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New thyroid models for ICRP pediatric mesh-type reference computational phantoms

  • Yeon Soo Yeom ;Chansoo Choi ;Bangho Shin ;Suhyeon Kim ;Haegin Han ;Sungho Moon ;Gahee Son;Hyeonil Kim;Thang Tat Nguyen;Beom Sun Chung;Se Hyung Lee ;Chan Hyeong Kim
    • Nuclear Engineering and Technology
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    • v.54 no.12
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    • pp.4698-4707
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    • 2022
  • As part of the ICRP Task Group 103 project, we developed ten thyroid models for the pediatric mesh-type reference computational phantoms (MRCPs). The thyroid is not only a radiosensitive target organ needed for effective dose calculation but an important source region particularly for radioactive iodines. The thyroid models for the pediatric MRCPs were constructed by converting those of the pediatric voxel-type reference computational phantoms (VRCPs) in ICRP Publication 143 to a high-quality mesh format, faithfully maintaining their original topology. At the same time, we improved several anatomical parameters of the thyroid models for the pediatric MRCPs, including the mass, overlying tissue thickness, location, and isthmus dimensions. Absorbed doses to the thyroid for the pediatric MRCPs for photon external exposures were calculated and compared with those of the pediatric VRCPs, finding that the differences between the MRCPs and VRCPs were not significant except for very low energies (<0.03 MeV). Specific absorbed fractions (target ⟵ thyroid) for photon internal exposures were also compared, where significant differences were frequently observed especially for the target organs/tissues close to the thyroid (e.g., a factor of ~1.2-~327 for the thymus as a target) due mainly to anatomical improvement of the MRCP thyroid models.

The Moderating Effect of Brand Power on the Effect of Service Quality on Customer Satisfaction and Recommendation in Aviation Industry (서비스 품질이 항공사 만족과 추천에 미치는 영향에 있어 브랜드 파워의 조절적 영향)

  • Park, Seunghae;Hong, Jaewon
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.1
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    • pp.35-44
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    • 2017
  • In this paper, we attempt to investigate the moderating effect of brand power on the effect of in-flight service quality on customer satisfaction and recommendation in the aviation industry. The results were as follows. First, in the case of high brand power FSC(full service carriers), the cost-to-benefit ratio as well as all other flight service properties influence to customer satisfaction. However, in the case of low brand power FSC, the cost-to-benefit ratio showed a greater impact of customer satisfaction compared to other in-flight services. Second, as in the case of customer satisfaction, while the cost-to-benefit ratio more influence to customer recommendation than other in-flight services in low brand power FSC, the cost-to-benefit ratio as well as all other flight service properties influence to customer recommendation together in high brand power FSC. Therefore, low brand power FSC required tit-for-tat strategy against to LCC(low cost carriers) by pursuing disruptive innovation for price. And high brand power FSC required sustaining innovation strategy through improving flight services.

Antimutagenic Effect of Green-Yellow Vegetables toward Aflatoxin $B_1$, and 4-Nitroquinoline-1-oxide (아플라톡신 $B_1$과 4-NQO에 대한 녹황색 채소류의 항돌연변이 효과)

  • 이경임;박건영;이숙희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.21 no.2
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    • pp.143-148
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    • 1992
  • The antimutagenic effects of green-yellow vegetables toward aflatoxin B$_1$(AFB$_1$) and 4-nitroquinoline-1-ox-ide (4-NQO) using the Ames assay system with Salmonella typhimurium TA98 and TA100 were studied. Forty six to fifty percent of the methanol extracts of the vegetable samples inhibited the mutagenicity induced by AFB$_1$in TA98 and TA100. Perilla leaf, lettuce, broccoli, crown daisy, water dropwort, small water dropwort, red pepper, red pepper leaves, amaranth, spinach and radish root were significantly reduced the mutagenicity of AFB$_1$(p< 0.01). Whereas 25 out of 27 samples (93%) exhibited antimutagenicity toward a direct mutagen of 4-NQO (p< 0.01. 0.05). The samples which showed the strong antimutagenicity (>60%) were cabbage, kale, lettuce, broccoli, mustard leaf, green red pepper, green sweet pepper, spinach, amaranth, soybean sprout and immature pumpkin. The juices from the several samples also showed antimu-tagenic activity toward AFB$_1$. Cabbage, perilla leaf, small water dropwort and spinach reduced TAT100 revertants dose dependently in the range of 50-500$m\ell$/plate, however, cucumber and carrot showed little effect.

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Complete Mitochondrial Genome Sequences of Korean Phytophthora infestans Isolates and Comparative Analysis of Mitochondrial Haplotypes

  • Seo, Jin-Hee;Choi, Jang-Gyu;Park, Hyun-Jin;Cho, Ji-Hong;Park, Young-Eun;Im, Ju-Sung;Hong, Su-Young;Cho, Kwang-Soo
    • The Plant Pathology Journal
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    • v.38 no.5
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    • pp.541-549
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    • 2022
  • Potato late blight caused by Phytophthora infestans is a destructive disease in Korea. To elucidate the genomic variation of the mitochondrial (mt) genome, we assembled its complete mt genome and compared its sequence among different haplotypes. The mt genome sequences of four Korean P. infestans isolates were revealed by Illumina HiSeq. The size of the circular mt genome of the four major genotypes, KR_1_A1, KR_2_A2, SIB-1, and US-11, was 39,872, 39,836, 39,872, and 39,840 bp, respectively. All genotypes contained the same 61 genes in the same order, comprising two RNA-encoding genes, 16 ribosomal genes, 25 transfer RNA, 17 genes encoding electron transport and ATP synthesis, 11 open reading frames of unknown function, and one protein import-related gene, tatC. The coding region comprised 91% of the genome, and GC content was 22.3%. The haplotypes were further analyzed based on sequence polymorphism at two hypervariable regions (HVRi), carrying a 2 kb insertion/deletion sequence, and HVRii, carrying 36 bp variable number tandem repeats (VNTRs). All four genotypes carried the 2 kb insertion/deletion sequence in HVRi, whereas HVRii had two VNTRs in KR_1_A1 and SIB-1 but three VNTRs in US-11 and KR_2_A2. Minimal spanning network and phylogenetic analysis based on 5,814 bp of mtDNA sequences from five loci, KR_1_A1 and SIB-1 were classified as IIa-6 haplotype, and isolates KR_1_A2 and US-11 as haplotypes IIa-5 and IIb-2, respectively. mtDNA sequences of KR_1_A1 and SIB-1 shared 100% sequence identity, and both were 99.9% similar to those of KR_2_A2 and US-11.

Effects of Herbal Remedy Using Onion (HRO-1) in Body Weight and Serum Level on Obesity in Rats (양파와 한약재를 이용하여 개발된 한약 복합 처방 (HRO-1)이 비만 흰쥐에 미치는 영향)

  • Kim, Kyung-Yoon;Kim, Hyung-Woo;Lee, Sang-Yeong;Hwang, Gui-Seong;Choi, Chan-Hun;Yoon, Gil-Jae;Jeong, Hyun-Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.3
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    • pp.562-566
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    • 2009
  • The aim of this study was to investigate the effects of herbal remedy using onion (HRO-1) supplementation on body weight change and cholesterol, triglyceride. free fatty acid, total lipid, phospholipid serum level in obesity mice. This study classified 32 of 4 weeks-old male C57BL/6 mice which have obesity caused by high fat fed into four groups of 8 mice and made the subjects medicated them HRO-1 for 6 weeks. Male C57BL/6 mice were divided into four groups; a normal group, a high-fat group, a high-fat group supplemented with HRO-1 (500 mg/kg), a high-fat group supplemented with HRO-1 (1000 mg/kg). In respect to the body weight change, there was statistically significant difference between the HRO-1 (1000 mg/kg) group compared to high-fat group (p<0.05). In the total cholesterol and LDL cholesterol level, there was statistically significant difference between the HRO-1 (1000 mg/kg) group compared to high-tat group (p<0.05). In the triglyceride and free fatty acid level, there was statistically significant difference between the normal group compared to high-fat group (p<0.05). In the total lipid and phospholipid level, there was statistically significant difference between the normal group compared to high-fat group (p<0.05). Also in the total lipid level, there was statistically significant difference between the HRO-1 group compared to high-fat group (p<0.05). The above results suggests that HRO-1 medicated is effective to prevention and treatment of obesity.

A Study on Accuracy of Position Fixes Obtained by GPS at Three Fixed Stations (정점(定點)에 있어서 GSP의 측위정도(測位精度))

  • Cho, Eul-Je
    • Journal of Fisheries and Marine Sciences Education
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    • v.3 no.2
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    • pp.19-28
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    • 1991
  • The United States has been developing a GPS(Global Positoning System), and now we can make use of it everywhere in the world. The author measured the usable time and took position fixes from three fixed stations in Japan in order to evaluate the positioning accuracy of GPS, firstly by the difference in the time of the year and, secondly by the difference in location between the stations in 1988. I was able to receive positioning signals from only 6 or 7 satellites, but in July 1991, 14 GPS satellites became available. The results obtained are summerized as follows: 1) The usable time was 7~9 hours from only 6~7 satellites. 2) In the case of the former, the time zone of position fixes varied with the time of the year and there were a little differences of the accuracy of position fixes except 3H(three dimensiomal high level positioning). In the case of the latter, there were not obvious locality differences in 3D(three dimensional positioning). But the positioning errors and number of data varied on each level in 2D(two dimensiomal positioning), although the positioning errors were smaller than 0.1 nautical mile. 3) Th standard deviations of Dep(departure) were larger than tat of D.lat(difference of latitude), and varied widely to the east and west. But the standard deviations were smaller than 100 meters.

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Sleep Quality and Poor Sleep-related Factors Among Healthcare Workers During the COVID-19 Pandemic in Vietnam

  • Thang Phan;Ha Phan Ai Nguyen;Cao Khoa Dang;Minh Tri Phan;Vu Thanh Nguyen;Van Tuan Le;Binh Thang Tran;Chinh Van Dang;Tinh Huu Ho;Minh Tu Nguyen;Thang Van Dinh;Van Trong Phan;Binh Thai Dang;Huynh Ho Ngoc Quynh;Minh Tran Le;Nhan Phuc Thanh Nguyen
    • Journal of Preventive Medicine and Public Health
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    • v.56 no.4
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    • pp.319-326
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    • 2023
  • Objectives: The coronavirus disease 2019 (COVID-19) pandemic has increased the workload of healthcare workers (HCWs), impacting their health. This study aimed to assess sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and identify factors associated with poor sleep among HCWs in Vietnam during the COVID-19 pandemic. Methods: In this cross-sectional study, 1000 frontline HCWs were recruited from various healthcare facilities in Vietnam between October 2021 and November 2021. Data were collected using a 3-part self-administered questionnaire, which covered demographics, sleep quality, and factors related to poor sleep. Poor sleep quality was defined as a total PSQI score of 5 or higher. Results: Participants' mean age was 33.20±6.81 years (range, 20.0-61.0), and 63.0% were women. The median work experience was 8.54±6.30 years. Approximately 6.3% had chronic comorbidities, such as hypertension and diabetes mellitus. About 59.5% were directly responsible for patient care and treatment, while 7.1% worked in tracing and sampling. A total of 73.8% reported poor sleep quality. Multivariate logistic regression revealed significant associations between poor sleep quality and the presence of chronic comorbidities (odds ratio [OR], 2.34; 95% confidence interval [CI], 1.17 to 5.24), being a frontline HCW directly involved in patient care and treatment (OR, 1.59; 95% CI, 1.16 to 2.16), increased working hours (OR, 1.84; 95% CI,1.37 to 2.48), and a higher frequency of encountering critically ill and dying patients (OR, 1.42; 95% CI, 1.03 to 1.95). Conclusions: The high prevalence of poor sleep among HCWs in Vietnam during the COVID-19 pandemic was similar to that in other countries. Working conditions should be adjusted to improve sleep quality among this population.

The Study on the Estimation of Optimal Debt Ratio in Korean Automobile Industry (국내 자동차산업의 적정부채비율 추정을 위한 실증연구)

  • Seo, Beom;Kim, Il-Gon;Park, Ji-Hun;Im, In-Seob
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.3
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    • pp.301-308
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    • 2018
  • This study explores an analytical mathematical model designed to estimate the optimal debt ratio of the Korean automobile industry, which has a more significant effect on the national economy than that of other industries, and attempts to estimate the optimal debt ratio based on objective data. The analytical model is based on ROA and ROE which uses the debt ratio as an independent variable and employs ROS, TAT, and NFCL as the related parameters. Regarding the NFCL, the optimal debt ratio is usually defined as the debt ratio that maximizes the ROA and ROE and is calculated using analytical procedures, such as by adding an equation that considers the debt ratio and the linearity relationship to the analytical model. This is because the optimal debt ratio can be calculated reliably by making use of an estimated value within a certain range, which is derived from more than two calculations rather than a single estimation starting from one calculation formula. In this study, for the estimation of the optimal debt ratio, the ROA and ROE are expressed as a quadratic equation with the debt ratio as the independent variable. Using this analysis procedure, the optimal debt ratio obtained using the data from the Korean automobile industry over a sixteen year period, which would optimize the profitability of the Korean automobile industry, was found to be 188% of the debt ratio in the ROA and 213% of the debt ratio in the ROE. This result was obtained by overcoming the problem of the reliability of the estimation value in spite of the limitations of the logical theory of this study, and can be interpreted as meaning that maintaining a debt ratio of 188% to 213% can enhance the profitability and reduce the risks in the Korean automobile industry. Furthermore, this indicates that the existing debt ratio of the Korean automobile industry is lower than the optimal value within the estimated range. Consequently, it is necessary for corporations to change their future debt ratio policies, given that the purpose of debt ratio management is to maintain safety and increase profitability, and to take into account the characteristics of the specific industry.

Numerical Study on Vertical Stress Estimation for Panel Pillars at Room and Pillar Mines (주방식 광산의 패널 광주 수직응력 추정을 위한 수치해석 연구)

  • Yoon, Dong-Ho;Song, Jae-Joon
    • Tunnel and Underground Space
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    • v.30 no.5
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    • pp.473-483
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    • 2020
  • This paper examines the vertical stress change concentrated on mine pillar which occurs due to the stress disturbance from opening excavation at room and pillar mine by FLAC3D, a finite difference method (FDM) software. The mesh size combination is decided with a careful consideration of relative error and run-time, then its performance is verified. A series of numerical analyses is conducted and the vertical stress at central pillar was observed for the test cases of 1×1 to 11×11 mine pillars, 40 m to 320 m depth with 40 m difference. The results show that the vertical stress of pillar approaches to the similar value with the value estimated by tributary area theory(TAT) when the development area (NP) is increased or the height of overburden (HOB) is decreased, while it is overestimated in the opposite case. Furthermore, it also represents that the vertical stress factor (VSF) converges to a specific value when the depth is increased whille keeping the development area identical.

Development of Detailed Korean Adult Eye Model for Lens Dose Calculation

  • Han, Haegin;Zhang, Xujia;Yeom, Yeon Soo;Choi, Chansoo;Nguyen, Thang Tat;Shin, Bangho;Ha, Sangseok;Moon, Sungho;Kim, Chan Hyeong
    • Journal of Radiation Protection and Research
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    • v.45 no.1
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    • pp.45-52
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    • 2020
  • Background: Recently, the International Commission on Radiological Protection (ICRP) lowered the dose limit for the eye lens from 150 mSv to 20 mSv, highlighting the importance of accurate lens dose estimation. The ICRP reference computational phantoms used for lens dose calculation are mostly based on the data of Caucasian population, and thus might be inappropriate for Korean population. Materials and Methods: In the present study, a detailed Korean eye model was constructed by determining nine ocular dimensions using the data of Korean subjects. The developed eye model was then incorporated into the adult male and female mesh-type reference Korean phantoms (MRKPs), which were then used to calculate lens doses for photons and electrons in idealized irradiation geometries. The calculated lens doses were finally compared with those calculated with the ICRP mesh-type reference computational phantoms (MRCPs) to observe the effect of ethnic difference on lens dose. Results and Discussion: The lens doses calculated with the MRKPs and the MRCPs were not much different for photons for the entire energy range considered in the present study. For electrons, the differences were generally small, but exceptionally large differences were found at a specific energy range (0.5-1 MeV), the maximum differences being about 10 times at 0.6 MeV in the anteroposterior geometry; the differences are mainly due to the difference in the depth of the lens between the MRCPs and the MRKPs. Conclusion: The MRCPs are generally considered acceptable for lens dose calculations for Korean population, except for the electrons at the energy range of 0.5-1 MeV for which it is suggested to use the MRKPs incorporating the Korean eye model developed in the present study.