• Title/Summary/Keyword: TAN-TAN

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Bioprospecting of Endophytic Fungi as Promising Anti-MRSA Agents

  • Wei, Yee-Min;Tan, Joo-Shun;Tang, Hock-Wei;Tong, Woei-Yenn;Leong, Chean-Ring;Tan, Wen-Nee
    • Natural Product Sciences
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    • v.28 no.3
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    • pp.93-104
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    • 2022
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to the global healthcare system. Ineffective and resistance to antibiotic treatments have increased morbidity and mortality rates worldwide. New and effective antibiotics are needed to combat against bacterial resistance. Endophytic fungi are crucial reservoirs of novel bioactive metabolites. In particular, the secondary metabolites show promising therapeutic potential, notably, antibacterial. This review discussed the emerging potential of endophytic fungi as anti-MRSA agents. The ecological sources of endophytic fungi were discussed with the synthesis of bioactive metabolites. The mode of antibacterial actions was elucidated to give a better understanding of the mechanisms involved. This review may serve as an important reference for future discovery and developments of anti-MRSA agents from endophytic fungi.

Mycena subpiligera sp. nov., a Symbiotic Species from China Associated with the Seed Germination of Gastrodia elata

  • Li-na Liu;Guo-ying Zhou;Ai-rong Shen;Bao-ming Shen;Yun Tan;Zhu-ming Tan
    • Mycobiology
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    • v.50 no.5
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    • pp.294-301
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    • 2022
  • Mycena subpiligera, a new taxon in sect. Fragilipedes that can strongly enhance the germination efficiency of Gastrodia elata seeds, was discovered in subtropical areas of China. As revealed by a morphological comparison with related Mycena species as well as maximum likelihood (ML) and Bayesian phylogenetic analyses based on sequences of the internal transcribed spacer (ITS) and the large subunit (LSU) regions of nuclear ribosomal RNA, the new taxon can be distinguished from phenotypically similar and phylogenetically related species. Optimal cultural conditions for M. subpiligera basidiomata are reported, and the germination rate of the new species is compared with that of M. citrinomarginata.

Imaging Spectrum of Augmented Breast and Post-Mastectomy Reconstructed Breast with Common Complications: A Pictorial Essay

  • Renuka Nair Kunju Krisnan;Niketa Chotai
    • Korean Journal of Radiology
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    • v.22 no.7
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    • pp.1005-1020
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    • 2021
  • Breast augmentation is becoming more common, be it for cosmetic reasons or post-mastectomy. Multiple articles in the literature describe the imaging findings of various types of cosmetic breast augmentation. Some articles describe imaging findings for different types of post-mastectomy reconstructions. This essay aims to serve as a comprehensive reference for the multimodality imaging of various types of breast augmentations in native breast and post-mastectomy reconstructions. Familiarity with these findings will facilitate the detection of complications and new or recurrent breast malignancies in patients. With the extensive illustrations provided in this essay on normal and abnormal imaging findings of augmented breasts, readers will receive exposure that will facilitate effective practice.