• Journal of Astronomy and Space Sciences
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• 제22권3호
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• pp.223-232
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• 2005

질량비가 작은 접촉쌍성 V410 Aur과V776 Cas를 소백산천문대의 61cm망원경에 2K CCD 카메라를 부착하여 측광 관측을 하였으며, 그 결과 이 별들의 새로운 3색(BVR)의 완전한 광도곡선을 얻었다. 새로운 광도곡선과 이미 발표된 분광관측으로부터 WD모델을 이용하여 이 두 별의 궤도요소와 절대 물리량을 얻었다. V410 Aur과 V776 Cas를 포함한 절대물리량이 잘 알려진 19개의 질량비가 작은 접촉쌍성들의 진화 상태를 조사하였다. 그 결과 질량비가 작은 접촉쌍성의 주성은 대부분 TAMS상에 놓이며 반성은 ZAMS 아래 놓이고 있음을 재확인하였다.

• 동의생리병리학회지
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• 제38권1호
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• pp.32-37
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• 2024

The aim of this study was to investigate the role of Daesiho-tang (Da Chai Hu-Tang) water extract (DSTE) in regulating chronic stress-induced cancer progression, focusing on its activity in modulating tumor-associated macrophages (TAMs). Different stimuli can polarize TAMs into immune-stimulating M1 macrophages or immunosuppressive M2 macrophages. During cancer progression, M2 phenotype increases and supports tumor growth, angiogenesis and metastasis. Notably, chronic stress-induced catecholamines promote M2 macrophage polarization. In this study, we investigated whether DSTE regulates norepinephrine (NE)-induced M2 macrophage polarization in RAW 264.7 mouse macrophage cells. Even though NE itself did not increase the expression of M2 markers, the conditioned media of NE-treated 4T1 mouse breast cancer cells (NE CM) significantly up-regulated M2 markers in RAW 264.7 cells, suggesting that NE-regulated cancer cell secretome stimulated M2 polarization. However, such increase was abrogated by DSTE. NE CM also induced phosphorylation of signal transducer and activator of transcription 6 (STAT6) in RAW 264.7 cells, which was clearly reversed by pretreatment with DSTE, demonstrating that DSTE inhibited M2 polarization by inactivating STAT6. Finally, M2-polarized RAW264.7 cells by NE CM markedly increased the migration of 4T1 cells. However, such increase was completely reversed by co-treating RAW264.7 cells with NE CM and DSTE, indicating that DSTE attenuated cancer cell migration by blocking M2 polarization. Taken together, our results suggest a probable use of DSTE for cancer patients under chronic stress by regulating M2 macrophage polarization.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2013년도 제48차 하계학술발표논문집 21권2호
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• pp.321-323
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• 2013

Supporting communications among users, Social Network has encouraged various information flows through relationships among them. This paper studies on mentality or attitude of Social Network Services (SNS for short) users, on the basis of Technology Acceptance Model (TAM for short) and then proposes so-called TAMS, Technology Acceptance Model for Social Network Services. SNS users make full use of SNS as channels in order to create, expand, and obtain some information related to personal concerns. We will research on how the benefits that users get by using SNS exert influence on user-perceived usability. The SNS-using benefits focus on relationship benefits that are formed by interactions among users. Provided that perceived usability affects mental or informational benefits according to involvement of SNS users, we will check how perceived usability or ease of use is connected to brand attitude.

• Journal of Astronomy and Space Sciences
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• 제16권2호
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• pp.227-240
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• 1999

소백산천문대의 61cm 망원경을 이용하여 1996년 5월 12일과 1999년 5월 5일부터 6월 8일까지 총 8일 밤 동안 W UMa 형 접촉쌍성 BV Dra의 CCD 측광광측을 수행하여 이 쌍성계의 BV R광도 곡선을 완성하였다. 우리의 관측으로부터 9개의 새로운 극심시간 (제1 극심: 5개, 제2 극심: 4개)을 산출하였고, 1999년 이후에 관측된 극심시간으로부터 새로운 광도요소를 결정하였다. 우리의 BV R광도곡선과 Batten & Lu (1986)의 시선속도곡선을 Wilson-Devinney 쌍성모델의 접촉모드 (Mode 3)에 적용하여 BV Dra의 측광 및 분광학적 해를 구하였다. 이 분석에서 광도곡선 비대칭의 원인을 흑점에 의한 것으로 가정하여 흑점이 있는 경우와 없는 경우로 나누어 1999년 광도곡선 해를 산출하였다. 그 결과, 우리는 이전의 연구자들에 의해 보고되지 않은 광도곡선 비대칭을 반성표면 위에 hot spot가 존재하고, 주성표면 위에 cool spot가 존재해서 일어난다고 해석하였다. 광도곡선과 시선속도곡선의 분석에 의해 산출한 BV Dra의 절대 물리량은 $M_1=0.40M_{odot}$, $M_2=1.01M_{odot}$, $R_1=0.72R_{odot}$, $R_2=0.40R_{odot}$ 이다. 이 절대 물리량을 이용하여 질량-반경도를 살펴본 결과, 질량이 작은 주성이 종년 주계열 (TAMS)근처에 있고, 질량이 큰 반성이 영년주계열 (ZAMS)근처에 위치하고 있다. 이는 질량-반경도에서 다른 W형 W UMa쌍성계의 위치와 매우 비슷하다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4871-4876
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• 2014

Background: We sought to evaluate the role of tumor associated macrophages (TAMs) on the promotion of coal tar pitch extract (CTPE)-induced tumorigenesis of human bronchial epithelial cells (BEAS-2B) and tumor metastasis in nude mice, and related mechanisms. Materials and Methods: BEAS-2B cells were first treated with 2.4 mg/mL CTPE for 72 hours. After removal of CTPE, the cells were continuously cultured and passaged using trypsin-EDTA. THP-1 cells were used as macrophage-like cells. BEAS-2B cells under different conditions (n=6/group) were injected into the back necks of nude mice, and alterations of tumor xenograft growth, indicative of tumorigenicity, and tumor metastasis were determined. Pathological changes (tumor nests and microvascular lesions) of HE-stained tumor tissues were also evaluated. The expression of AP-1(c-Jun) in xenografts and metastatic tumors was determined using immunohistochemistry. Results: Tumor size and weight in nude mice transplanted with the mixture of CTPE-induced passage 30 BEAS-2B and THP-1 cells (2:1) were increased compared to those from the CTPE-treated BEAS-2B cells at passage 30 alone at different observation time points. Tumor metastasis to lymph nodes and liver was only detected after transplantation of a mixture the two kinds of cells. The numbers of tumor nests and microvascular lesions, and the expression levels of AP-1 (c-Jun) in tumors from the mixture of two kinds of cells were increased apparently in contrast to those in tumor from the CTPE-treated BEAS-2B cells of passage 30 alone. In addition, there was positive correlation between AP-1 (c-Jun) expression level and the number of microvascular lesions, or between AP-1 (c-Jun) expression level and tumor metastasis in these two groups. Conclusions: TAMs not only facilitate tumorigenesis transformation of CTPE-induced BEAS-2B cells, but also promote tumor growth, angiogenesis and metastasis in nude mice in vivo, which may be mediated by AP-1.

• Journal of Astronomy and Space Sciences
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• 제22권3호
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• pp.233-242
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• 2005

66개의 근접촉쌍성(이하 NCBb)의 절대물리량과 궤도요소를 여러 목록으로부터 수집 분석하여 여러 물리량 사이의 상관관계와 NCBs의 물리적 특성을 조사하였다 NCBs의 질량비-광도비 관계는 $L_2/L_1{\lapprox}(M_2/M_1)^{1.45}$로 나타났으며 CE형에 더 근접한 특성을 보였다. NCBs의 여러 물리량 사이의 상관관계에 따르면 F형이 A형에 비하여 주성과 반성의 질량, 반경, 광도 및 온도의 차이가 작게 나타났다. NCBs의 H-R도에 따르면 A형이 F형에 비하여 다소 더 진화된 종년주계열(TAMS)에 가까이 나타나고 있다.

• 셀메드
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• 제6권1호
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• pp.2.1-2.9
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• 2016

Traditional system of medicine mentioned the use of plants in treatment of various human ailments. Mochrus (Bombax ceiba Linn.) is one of the medicinal plants used in Unani medicine since time immemorial. It is a very tall tree with approximately 150 feet height. It is widely found in temperate Asia, tropical Asia, Africa and Australia. In India, it can be found at altitudes up to 1500 m. In peninsular India, the tree is very common in the dry as well as moist deciduous forests and near rivers. It is reported to possess qabiz (constipative); mujaffif (siccative); muqawwi rehm (uterine tonic); nafi sailan rehm (beneficial in leucorrhea); mumsik wa mughalliz mani (increase consistency of semen); muallide mani (production of semen); habise tams (amenorrhoic); dafi fasaad khoon wa safra (purifies blood and bile); taskeen hiddat aza (hotness of organs); muqawi asnan wa lissa (tonic to teeth and gums) etc. Ethnobotanical studies prove that it is used in diarrhoea, asthma, impotency, boils, wounds, leprosy, pimples and many other skin diseases. It is an anthelmintic remedy since ancient time. Pharmacological studies like hypotensive, antioxidant, analgesic, anti-inflammatory, antipyretic, antiangiogenic, anti- bacterial, cytotoxic, hepatoprotective, diuretic, anthelmintic, anticancer, spermatogenic and anti-helicobacter pylori activities have been evaluated for various parts of this plant that confirms to its use in classical medicine.

• Archives of Plastic Surgery
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• 제51권1호
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• pp.118-125
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• 2024

Tamai zone 4 replantation, defined as the replantation at a level proximal to the flexor digitorum superficialis' insertion and distal to where the common digital artery branches into the proper digital artery, has poor functional results because making orthosis and rehabilitation protocols that protect the bone and the flexor and extensor tendons simultaneously difficult. Two cases of Tamai zone 4 replantation are presented: one case of an index finger replantation at the proximal phalanx and a case of ring finger replantation at the proximal interphalangeal joint. The author did not repair the flexor tendon intentionally in the primary replantation and performed two-stage flexor tendon reconstruction later. The total active motions (TAMs) at the last follow-up were 215 and 180 degrees, respectively, with the latter distal interphalangeal joint being an arthrodesis. Both cases had no extension lag in the proximal interphalangeal joint. These results were much better than those in previous reports, in which the mean TAM was 133 degrees or less. The good results appeared to be mainly due to the reasonable and clear postoperative rehabilitation protocols made by the proposed procedure. This procedure may be useful for obtaining reproducible functional results even in Tamai zone 4 replantation.

• 셀메드
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• 제2권4호
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• pp.33.1-33.3
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• 2012

Menorrhagia (kasrate tams) is the most common gynecologic complaint in contemporary gynecology, affecting 10 to 15% of the adult female population. It can occur at any age. In the Unani system of medicine, since antiquity, dry cupping therapy (hijamat bila shurt) has been used to treat menorrhagia. An effort was made to evaluate the usefulness of dry cupping on excessive menstrual blood loss in menorrhagia with a well validated menstrual pictogram. This study was conducted on 15 patients at the National Institute of Unani Medicine, Hospital Bangalore, from January 2010 and July 2010. Unmarried or married patients aged 17 - 47 year with a history of excessive or prolonged bleeding per vaginum were included. Two large cups (with 5.7 cm internal diameter) were applied below each breast for 15 min, only once during the menstrual period when the patient reported to the outpatient department. If the menstrual flow was not reduced, the next day again dry cupping was repeated. The outcome was to assess the efficacy of dry cupping on the reduction in the amount of menstrual blood loss. The data was analyzed by the Wilcoxon matched test. The mean scores of menstrual blood loss before and after the treatment was 400.26 (277.95) and 48.4 (32.082) ml respectively, p = 0.002, considered statistically significant. A dry cupping therapy is a useful treatment modality in decreasing the amount of menstrual blood flow in menorrhagia. Further randomized controlled clinical trials and validation are needed in a large population.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.5589-5597
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• 2013

The aim of this review article was to evaluate the relationship and the possible etiological mechanisms between endometriosis, leiomyoma (LM) and adenomyosis and gynecological cancers, such as ovarian and endometrial cancer and leiomyosarcoma (LMS). MEDLINE was searched for all articles written in the English literature from July 1966 to May 2013. Reports were collected systematically and all the references were also reviewed. Malignant transformation of gynecologic benign diseases such as endometriosis, adenomyosis and LM to ovarian and endometrial cancer remains unclear. Hormonal factors, inflammation, familial predisposition, genetic alterations, growth factors, diet, altered immune system, environmental factors and oxidative stress may be causative factors in carcinogenesis. Early menarche, low parity, late menopause and infertility have also been implicated in the pathogenesis of these cancers. Ovarian cancers and endometriosis have been shown to have common genetic alterations such as loss of heterozygosity (LOH), PTEN, p53, ARID1A mutations. MicroRNAs have also been implicated in malignant transformation. Inflammation releases proinflammatory cytokines, and activates tumor associated macrophages (TAMS) and nuclear factor kappa b (NF-KB) signaling pathways that promote genetic mutations and carcinogenesis. MED12 mutations in LM and smooth muscle tumors of undetermined malignant potential (STUMP) may contribute to malignant transformation to LMS. A hyperestrogenic state may be shared in common with pathogenesis of adenomyosis, LM and endometrial cancer. However, the effect of these benign gynecologic diseases on endometrial cancer should be studied in detail. This review study indicates that endometriosis, LM, adenomyosis may be associated with increased risk of gynecological cancers such as endometrial and ovarian cancers. The patients who have these gynecological benign diseases should be counseled about the future risks of developing cancer. Further studies are needed to investigate the relationship between STUMPs, LMS and LM and characteristics and outcome endometrial carcinoma in adenomyotic patients.