• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.211-226
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• 2019

Pig CD45, the leukocyte common antigen, is encoded by the PTPRC gene and CD45 is a T cell-type specific tyrosine phosphatase with alternative splicing of its exons. The CD45 is a coordinated regulator of T cell antigen receptor (TCR) signal transduction achieved by dephosphorylating the phosphotyrosine of its substances, including $CD3{\zeta}$ chain of TCR, Lck, Fyn, and Zap-70 kinase. A dysregulation of CD45 is associated with a multitude of immune disease and has been a target for immuno-drug discovery. To characterize its key structural features with the effects of regulating TCR signaling, this study predicted the unknown structure of pig CD45RO (the smallest isoform) and the complex structure bound to the ITAM (REEpYDV) of $CD3{\zeta}$ chain via homology modeling and docking the peptide, based on the known human CD45 structures. These features were integrated into the structural plasticity of extracellular domains and functional KNRY and PTP signature motifs (the role of a narrow entrance into ITAM binding site) of the tyrosine phosphatase domains in a cytoplasmic region from pig CD45RO. This contributes to the selective recognition of phosphotyrosine from its substrates by adjusting the structural stability and binding affinity of the complex. The characterized features of pigCD45RO can be applied in virtual screening of the T-cell specific immunomodulator.

• Food Science of Animal Resources
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• v.39 no.1
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• pp.45-53
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• 2019

This study observed the effects of the double combination of temperatures-times (2 temperatures: 2 times combination, 2T2T) in sous vide cooking method on the physicochemical properties and collagen solubility (CS) of semitendinosus muscle from cattle and goat as a comparison to common sous vide treatment (1 temperature: 1 time combination, 1T1T). The new invention of sous vide cooking method (2T2T) cooked at the first temperature at $45^{\circ}C$ for 3 h, and the second temperature at $60^{\circ}C$, $65^{\circ}C$, and $70^{\circ}C$ for 3 h, and labeled as N45-60, N45-65, and N45-70, respectively. While, common sous vide treatment (1T1T) were cooked directly for 6 h at $60^{\circ}C$ (T60), $65^{\circ}C$ (T65), and $70^{\circ}C$ (T70). Results revealed that cooking with 2T2T treatment improved the water-holding capacity and reduced the cooking loss of both beef and goat meat. The $L^*$ values have no apparent changes between treatment in beef and goat meat, while $a^*$ values of N45-60 treated goat presented markedly higher values than other treatments but an only slight increase in beef at the same treatment (p>0.05). Again, 2T2T treatment tended to decrease mean shear force (SF) values for beef and goat meat with the lowest SF values recorded at N45-60, and the CS no or less influenced this value. Therefore, the application of innovative sous vides cooking method (2T2T) presented comparable values in the treated beef and goat meat as compared to common sous vide method (1T1T).

• Composites Research
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• v.22 no.3
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• pp.60-65
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• 2009

The mechanical behavior of carbon fiber reinforced polymeric (CFRP) composites was investigated. Both strength and modulus were measured at room temperature dry, cold temperature dry, $-55^{\circ}C$, and elevated temperature wet, $82.2^{\circ}C$ on seven different laminate configurations consisting of $[0_6]_T$, $[90_{12}]_T$, $[0_{16}]_T$ and $[90_{16}]_T$ unidirectional laminates, $[{\pm}45]_{5S}$ angle-ply laminate, $[0/90_{12}/0]_T$ cross-ply laminate, a 36-ply laminate $[0/45/-45/45/-45/0]_{3S}$. Based on the experimental data presented, it is shown that the strength at cold temperature dry, $-55^{\circ}C$ is increased with the brittleness of fiber or matrix. Moreover, it is shown that both shear strength and modulus at elevated temperature wet, $82.2^{\circ}C$ are decreased by the cause of interfacial deterioration between fiber and matrix with moisture absorption.

• Journal of Korean Society of Forest Science
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• v.99 no.3
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• pp.397-403
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• 2010

This study was conducted to investigate the changes in soil temperature, soil moisture content, light availability (photosynthetically active radiation, PAR) and diameter growth in 46-year-old Korean pine (Pinus koraiensis Siebold et Zuccarini) plantation located in Gwangneung experimental forest after 4 years from thinning. Three different thinning intensities [control, 45%(T45), and 60%(T60) basal area reduction] were applied in 2004. Mean soil temperature and soil water content were $8.9^{\circ}C$ and 14.3% for control, $10^{\circ}C$ and 16.1% for T45 and $10.2^{\circ}C$ and 16.1% for T60, respectively. Mean soil temperature and moisture content were significantly different among the treatment plots (p<0.05). Mean PAR in control, T45 and T60 was 44, 143 and178 ${\mu}mol/m^2$/sec, respectively and the differences were also statistically significant among the treatment plots (p<0.05). Mean annual diameter growth in control, T45 and T60 was 0.4, 1.5 and 1.2 mm, respectively. Diameter growth of Pinus koraiensis was steadily increased after thinning in comparison to control. Consequently, the results suggested that soil temperature, soil moisture content and light availability were likely to last beyond the 4 years after thinning in this Korean pine plantation.

• Bulletin of the Society of Naval Architects of Korea
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• v.25 no.4
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• pp.58-68
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• 1988

This paper is concerned with mechanical properties of unidirectional laminate $[(0^{\circ})_{8T},\;(90^{\circ})_{8T}]$, composed of angle plies $[({\pm}15^{\circ})_{2S},\;({\pm}30^{\circ})_{2S},\;({\pm}45^{\circ})_{2S},\;({\pm}60^{\circ})_{2S},\;({\pm}75^{\circ})_{2S}$ and laminate $[(9^{\circ}/90^{\circ})_{2S},\;(90^{\circ}/{\pm}45^{\circ}/0^{\circ})_S,\;({\pm}45^{\circ}/0^{\circ}/{\pm}90^{\circ})_S,\;({\pm}45^{\circ}/90^{\circ}/0^{\circ})_S,\;(0^{\circ}/90^{\circ}/{\pm}45^{\circ})_S,\;(90^{\circ}/0^{\circ}/{\pm}45^{\circ})_S]$ under the condition of uniform strain tension. Also, experimental investigation was conducted $[10]_{8T}$, off-axis tensile test for intralaminar shear characterization. The experimental data on the failure criterion of tensor polynomial were compared with those from the classical laminate theory. Acoustic Emission experiments have been carried out to investigate the changes of the amplitude distributions of Acoustic Emission monitored during failure of tensile tests on Carbon/Epoxy composites.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.59 no.3
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• pp.189-195
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• 2023

This study quantitatively evaluated size selectivity for three netting shapes (T0; regular, T45, T90) and hanging ratio (35%, 70%) of T0 netting used for trawl codend. The size selectivity experiment was performed in a tank using a cube experimental model with a length of 50 cm on one side and 389 experimental individuals, jack mackerel (Trachurus japonicus). In the selectivity analysis, a selectivity curve was created based on the selection ratio using a logistic function, and the 25%, 50%, and 70% selection length and selection range (SR) were obtained. The T0 netting was 19.54 cm when the 50% selective length, which is a selectivity evaluation index, had a hanging ratio of 35%, a selection range of 0.51 cm, and 22.70 cm and 3.08 cm for the hanging ratio of 70%. The T45 netting was 24.34 cm and 2.13 cm, and the T90 netting was 23.51 cm and 2.84 cm. The results of the T45 netting and the T90 netting are similar, and the 50% selection length and selection range were relatively larger than the T0 netting. There was a significant difference in the correlation between the circumference of the inner circle of the mesh by the shape of the netting and the body girth of the experimental individual (Pearson test, r = 0.86, p < 0.05). There was no significant difference in the correlation between the selection ratio by the T0 netting, T45 netting, and T90 netting with a 70% hanging ratio (one-way ANOVA, p > 0.05). The results of this study showed that selectivity such as T45 netting and T90 netting appeared when the hanging ratio, which maximizes the area of T0 netting, was maintained at 70%.

• Proceedings of the KWS Conference
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• 2000.10a
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• pp.235-237
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• 2000

• Journal of Oral Medicine and Pain
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• v.34 no.4
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• pp.363-369
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• 2009

Erosive oral lichen planus (EOLP) and recurrent aphthous stomatitis (RAS) are T-cell mediated inflammatory immune disorders. It was investigated mRNA expression pattern of several regulatory factors, such as, CD28, CD45, CD152, CD154, CD279, which influence T lymphocyte in unstimulated whole saliva (UWS) of EOLP and RAS patients. It was collected unstimulated whole saliva during 10 minute in EOLP 18 people, RAS patients 12 people, healthy control 8 people. We investigated mRNA expression of T lymphocyte regulatory factors, such as, CD28, CD45, CD152, CD154, CD279, with real time reverse transcription polymerase chain reaction. In EOLP group, CD45, CD279 expressed higher and CD154 expressed lower than control. In RAS, CD45, CD270 expressed higher and CD28, CD154 expressed lower than control. In addition CD152 salivary mRNA expression of EOLP is higher than that of RAS. The above results were suggested that the mRNA expression of T lymphocyte regulatory factors in unstimulated whole saliva of EOLP and RAS contributes to diagnosis of diseases.

• Fashion & Textile Research Journal
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• v.2 no.3
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• pp.234-238
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• 2000

In this study it was measured seam strength of T/C which has the different processing methods and density. Also it was measured seam strength by the change of angle in the pattern and the kinds of threads. The results of this study are as follows; The seam strength is stronger in order of $90^{\circ}/90^{\circ}$ > $0^{\circ}/0^{\circ}$ > $70^{\circ}/-70^{\circ}$ > $70^{\circ}/70^{\circ}$ > $60^{\circ}/60^{\circ}$ > $60^{\circ}/-60^{\circ}$ > $30^{\circ}/30^{\circ}$ > $30^{\circ}/-30^{\circ}$ > $45^{\circ}/-45^{\circ}$ > $45^{\circ}/45^{\circ}$ by the cutting directions, in order of T/C3>T/C1>T/C4>T/C2 by the samples and in order of 60's/3>40's/2>60's/2>50's/2 by the threads.

• Bulletin of the Korean Mathematical Society
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• v.45 no.2
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• pp.241-252
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• 2008

By means of a Riccati transform and averaging technique some oscillation criteria are established for perturbed nonlinear differential equations of second order $(P_1)\;(p(t)x'(t))'+q(t)|x({\phi}(t)|^{{\alpha}+1}sgnx({\phi}(t))+g(t,\;x(t))=0$ $(P_2)$ and $(P_3)$ satisfying the condition (H). A comparison theorem and examples are given.