• Title/Summary/Keyword: T2 강조영상

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Analysis of Distances for MRI Scan to Maintain Pptimal Signal Intensity in a Surface Coil (MRI 검사 시 코일내 최적의 신호강도를 유지할 수 있는 거리의 기준 분석)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.158-164
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    • 2018
  • The purpose of this study is to statistically analyze the signal intensity pattern according distance from the surface coil center and to maintain optimal signal intensity under clinical circumstances where the surface coil centers are not correctly positioned due to various causes. The cylindrical fluid phantom was placed and moved from the coil center in vertical direction with 1 cm increments. The signal intensities were measured and compared. As a result, the signal intensity showed no significant difference within 4 cm and 1 cm from in T1 weighted images while in T2 weighted images the signal intensity was maintained up to 5 cm and lower 3 cm in the upper and lower direction from the coil center. In conclusion, to maintain the optimal signal intensity the target region should be located within the reference distances proposed in this study.

Merkel Cell Carcinoma of the Trunk: Two Case Reports and Imaging Review (몸통에 생긴 메르켈 세포암종: 2예 증례 보고 및 영상 소견 고찰)

  • Ha Yun Oh;Donghan Kim;Yun Sun Choi;EunKyung Kim;Tae Eun Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.5
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    • pp.1134-1139
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    • 2023
  • Merkel cell carcinoma (MCC) is a rare malignant cutaneous tumor primarily located in the head and neck. We report the imaging features of pathologically confirmed MCC in the trunk. On US, MCC showed heterogeneous echogenicity with perpendicular hypoechoic linear bands that resembled "columns of smoke" in the skin and subcutaneous layers as well as prominent vascularity. On MRI, the tumor showed hypointensity on T1-weighted images and hyperintensity on proton density and T2-weighted images with linear low-signal bands in the skin and subcutaneous layers as well as intense enhancement on T1-enhanced images. Although MCC has nonspecific imaging features, these characteristics may be helpful for the early diagnosis of this disease.

Software Development for the Integrated Visualization of Brain Tumor and its Surrounding Fiber Tracts (뇌종양 및 그 주변 신경다발의 통합적 가시화를 위한 소프트웨어의 개발)

  • Oh Jungsu;Cho Ik Hwan;Na Dong Gyu;Chang Kee Hyun;Park Kwang Suk;Song In Chan
    • Investigative Magnetic Resonance Imaging
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    • v.9 no.1
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    • pp.2-8
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    • 2005
  • Purpose : The purpose of this study was to implement a software to visualize tumor and its surrounding fiber tracts simultaneously using diffusion tensor imaging and examine the feasibility of our software for investigating the influence of tumor on its surrounding fiber connectivity. Material and Methods : MR examination including T1-weigted and diffusion tensor images of a patient with brain tumor was performed on a 3.0 T MRI unit. We used the skull-striped brain and segmented tumor images for volume/surface rendering and anatomical information from contrast-enhanced T1-weighted images. Diffusion tensor images for the white matter fiber-tractography were acquired using a SE-EPI with a diffusion scheme of 25 directions. Fiber-tractography was performed using the streamline and tensorline methods. To correct a spatial mismatch between T1-weighted and diffusion tensor images, they were coregistered using a SPM. Our software was implemented under window-based PC system. Results : We successfully implemented the integrated visualization of the fiber tracts with tube-like surfaces, cortical surface and the tumor with volume/surface renderings in a patient with brain tumor. Conclusion : Our result showed the feasibility of the integrated visualization of brain tumor and its surrounding fiber tracts. In addition, our implementation for integrated visualization can be utilized to navigate the brain for the quantitative analysis of fractional anisotropy to assess changes in the white matter tract integrity of edematic and peri-edematic regions in a number of tumor patients.

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Glutaric Aciduria Type I

  • Sin, U-Jong;Mun, Yeo-Ok;Dong, Eun-Sil;An, Yeong-Min;Yun, Hye-Ran;Yamaguchi, Seiji
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.2 no.1
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    • pp.1-6
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    • 2002
  • 출생 이후 머리둘레가 커지는 1개월 남아에게서 뇌초음파상 지주막하 공간이 확장되어 있고 백질의 음영이 증가되어 있었고 뇌 MRI 소견은 sylvian fissure의 확장과 양측 대뇌, 소뇌 피질과 백질이 T1 강조 영상에서 저신호강도와 T2 강조영상에서 고신호강도를 보였고 검사상 GA1 의심되었고 경피생검으로 얻은 섬유아세포 배양에서 glutaryl CoA dehydrogenase의 활성도가 전혀 없어 GA1을 확진하게 되었다. 이후 특수분유인 Glutatex(Abbott사) 수유와 riboflavin, carnitine 보충요법을 시행하여 대사성 위기나 급성 뇌증 위기는 없었고 양호히 발달하는 것을 경험하였기에 보고하는 바이다.

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Evaluation of Magnetization Transfer Ratio Imaging by Phase Sensitive Method in Knee Joint (슬관절 부위에서 자화전이 위상감도법에 의한 자화전이율 영상 평가)

  • Yoon, Moon-Hyun;Seung, Mi-Sook;Choe, Bo-Young
    • Progress in Medical Physics
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    • v.19 no.4
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    • pp.269-275
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    • 2008
  • Although MR imaging is generally applicable to depict knee joint deterioration it, is sometimes occurred to mis-read and mis-diagnose the common knee joint diseases. In this study, we employed magnetization transfer ratio (MTR) method to improve the diagnosis of the various knee joint diseases. Spin-echo (SE) T2-weighted images (TR/TE 3,400-3,500/90-100 ms) were obtained in seven cases of knee joint deterioration, FSE T2-weighted images (TR/TE 4,500-5,000/100-108 ms) were obtained in seven cases of knee joint deterioration, gradient-echo (GRE) T2-weighted images (TR/TE 9/4.56/$50^{\circ}$ flip angle, NEX 1) were obtained in 3 cases of knee joint deterioration, In six cases of knee joint deterioration, fat suppression was performed using a T2-weighted short T1/tau inverse recovery (STIR) sequence (TR/TE =2,894-3,215 ms/70 ms, NEX 3, ETL 9). Calculation of MTR for individual pixels was performed on registration of unsaturated and saturated images. After processing to make MTR images, the images were displayed in gray color. For improving diagnosis, three-dimensional isotropic volume images, the MR tristimulus color mapping and the MTR map was employed. MTR images showed diagnostic images quality to assess the patients' pathologies. The intensity difference between MTR images and conventional MRI was seen on the color bar. The profile graph on MTR imaging effect showed a quantitative measure of the relative decrease in signal intensity due to the MT pulse. To diagnose the pathologies of the knee joint, the profile graph data was shown on the image as a small cross. The present study indicated that MTR images in the knee joint were feasible. Investigation of physical change on MTR imaging enables to provide us more insight in the physical and technical basis of MTR imaging. MTR images could be useful for rapid assessment of diseases that we examine unambiguous contrast in MT images of knee disorder patients.

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Optimal Flip Angle for T2-Weighted Effect in Micro 4.7T MRI SE Sequence (마이크로 4.7T MRI SE Sequence에서 T2강조효과를 위한 최적의 Flip Angle)

  • Lee, Sang-Ho
    • Journal of radiological science and technology
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    • v.42 no.2
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    • pp.113-117
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    • 2019
  • The purpose of this study was to investigate the FA value which can produce the best T2-weighted images by measuring the signal intensity and noise according to the FA value change in the brain image and the abdominal image of the mouse using micro-MRI. Brain imaging and abdominal imaging of BALB / C mice weighing 20g were performed using 4.7T (Bruker BioSpin MRI GmbH) micro-MRI equipment, Turbo RARE-T2 (spin echo-T2) images were scanned at TR 3500 msec and TE 36 msec. The changes of the FA values were $60^{\circ}$, $80^{\circ}$, $100^{\circ}$, $120^{\circ}$, $140^{\circ}$, $160^{\circ}$ and $180^{\circ}$. We measured signal intensity according to FA values of ventricle and thalamus in brain imaging, The signal intensity of kidney and muscle around the kidney was measured in abdominal images. To obtain SNR and CNR, we measured the background signals of two different parts, not the tissue. In the brain (thalamus) image, the signal intensity of FA $100^{\circ}$ was 7,433 and SNR (6.49) was the highest. In the abdominal (kidney) image, the signal intensity was highest at 16,523 when FA was $120^{\circ}$, and the highest SNR was 8.54 when FA was $140^{\circ}$. The CNR value of the brain image was 1.38 at FA $60^{\circ}$ and gradually increased to 8.29 at FA $180^{\circ}$. The CNR value of the muscle adjacent to the kidney gradually increased from 2.36 when the FA value was $60^{\circ}$ and the highest value was 4,57 at the FA value $180^{\circ}$.

Usefulness of Dual-Echo in Steady State (DESS) Image in Chondromalacia of Knee Joint: Comparison of DESS and Turbo Spin-Echo MR Images (슬관절 연골 연화증의 진단에서의 Dual Echo in Steady State (DESS) 영상의 유용성 : 급속 스핀에코 자기공명 영상과 비교)

  • 윤삼현;하두회
    • Investigative Magnetic Resonance Imaging
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    • v.3 no.1
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    • pp.66-72
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    • 1999
  • Purpose : To evaluate the usefulness of Dual Echo in Steady State(DESS) image in the diagnosis of chondromalacia of the knee compared with turbo spin-echo MR images Materials and Methods : We included 26 patients with chondromalacia of the knee. MR imaging was obtained with a 1.5T imager. Sagittal and coronal double echo T2 weighted images(TR/TE 3000-4200/16-96msec, FOV $140-160{\times}140-160mm$, matrix size $180{\times}256$, slice thickness 4.0mm, interslice gap 0.5mm), and sagittal DESS image(TR/TE 25.4/9.0msec, flip angle $35-45^{\circ}$, FOV $150-160{\times}150-160mm,{\;}matrix{\;}size{\;}192{\times}256$, effective slice thickness 1.5mm) were obtained. Cartilage lesions were staged according to a modified scheme proposed by Outerbirdge: grade 0, normal; grade 1, softening or/and swelling; grade 2, mild surface fibrillation or/and less than 50% of cartilage thickness; grade 3, severe surface fibrillation or/and loss of more than 50% of cartilage thickness but without exposure of subchondral bone; and grade 4, complete loss of cartilage with subchondral bone exposure. Gradings were determined by two readers with consensus, and patellofemoral, medial and lateral tibiofemoral compartments were evaluated. Results : Arthroscopic findings revealed grade 1 in seven cases, grade 2 in 21 cases, grade 3 in six cases, and grade 4 in 18 cases. Sensitivity of turbo spin-echo MR image was as follows; 0%, 14%, 0%, 61% in each grade, and sensitivity of DESS image was as follows; 0%, 33%, 50%, 67%, in each grade(p=0.001). In the detection of chondromalacic lesions regardless of gradings, sensitivity, specificity and accuracy of conventional MR image were 59.6% 88.6% 78.8%, and of DESS image, 73.1% 88.4%, 82.2%(p=0.007). Conclusion : For chondromalacia of knee joints, DESS images showed higher sensitivity than turbo spin-echo MR images. Therefore, DESS images will be helpful for diagnosis of chondromalacia of knee joints.

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3T MR Imaging에 적합한 RF Surface Coil의 개발 : 피부 미세구조에 대한 예비 연구

  • 윤성익;이정우;최보영;이형구;서태석
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.48-48
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    • 2003
  • Abstract: 현대 질병의 최종진단은 세포수준의 해부형태학적 연구가 일반적이며 광학현미경이나 전자현미경을 이용한 병리조직학적 소견을 바탕으로 진단되어지고 있다. 이러한 진단에는 In vivo 검사가 거의 불가능하여 주로 생검을 통한 연구만 수행되고 있어 진단함에 있어 단계적인 불편이 초래될 뿐만 아니라 악성 종양의 전이를 유발시킬 수 있고 또한 생리 및 생화학적 분석이 어렵다. 이러한 문제점을 해결하기 위해 고분해능의 RF Surface Coil을 개발하여 In vivo 및 비침습적인 방법인 MR Technology를 이용하고자 한다. Introduction: 피부조직과 같은 미세 인체구조 연구를 위해 고해상도 3T MRI 시스템에 적합한 고분해능의 RF surface coil을 개발하고 있다. In vivo 연구를 위한 여러 parameter를 최적화하여 기능영상에도 부합된다. 비침습적인 In vivo 검사에 의한 세포수준의 극 미세구조의 연구가 가능해짐으로써 과거 시행하던 침습적인 생검없이 각종질환의 진단적 접근이 병리학적 수준으로 향상되어 질병의 정확한 진단이 가능해지게 될 것이다. Method: 고분해능의 RF Surface Coil을 제작하여 3T MR 장비에서 피부 미세구조연구에 보다 적합하도록 In vivo 및 In vitro 실험을 수행하였다. In vitro 실험은 In vivo 연구를 위한 여러 parameter들을 최적화하기 위한 기초 실험을 하였고 다양한 팬톰들을 이용하여 Tl 강조영상, T2 강조영상을 획득하였으며, SNR을 높이기 위한 개선에 대한 연구를 수행하였다. In vivo 실험은 정상피부에서 다양한 부위에 대한 피부영상의 예비 연구를 수행하였다. Result and Discussion: 비침습적인 In vivo 검사에 의한 세포수준의 극 미세구조의 연구가 가능해짐으로써 과거 시행하던 침습적인 생검없이 각종질환의 진단적 접근이 병리학적 수준에서 가능해짐으로써 질병의 정확한 진단이 가능해지게 될 것이다. Acknowledgement: 본 연구는 2002 년도 한국과학재단 목적기초연구사업 (과제번호 : R0l-2002-000-00294-0 (2002)) 지원아래 수행되었다.

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Gaussian Filtering Effects on Brain Tissue-masked Susceptibility Weighted Images to Optimize Voxel-based Analysis (화소 분석의 최적화를 위해 자화감수성 영상에 나타난 뇌조직의 가우시안 필터 효과 연구)

  • Hwang, Eo-Jin;Kim, Min-Ji;Jahng, Geon-Ho
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.4
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    • pp.275-285
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    • 2013
  • Purpose : The objective of this study was to investigate effects of different smoothing kernel sizes on brain tissue-masked susceptibility-weighted images (SWI) obtained from normal elderly subjects using voxel-based analyses. Materials and Methods: Twenty healthy human volunteers (mean $age{\pm}SD$ = $67.8{\pm}6.09$ years, 14 females and 6 males) were studied after informed consent. A fully first-order flow-compensated three-dimensional (3D) gradient-echo sequence ran to obtain axial magnitude and phase images to generate SWI data. In addition, sagittal 3D T1-weighted images were acquired with the magnetization-prepared rapid acquisition of gradient-echo sequence for brain tissue segmentation and imaging registration. Both paramagnetically (PSWI) and diamagnetically (NSWI) phase-masked SWI data were obtained with masking out non-brain tissues. Finally, both tissue-masked PSWI and NSWI data were smoothed using different smoothing kernel sizes that were isotropic 0, 2, 4, and 8 mm Gaussian kernels. The voxel-based comparisons were performed using a paired t-test between PSWI and NSWI for each smoothing kernel size. Results: The significance of comparisons increased with increasing smoothing kernel sizes. Signals from NSWI were greater than those from PSWI. The smoothing kernel size of four was optimal to use voxel-based comparisons. The bilaterally different areas were found on multiple brain regions. Conclusion: The paramagnetic (positive) phase mask led to reduce signals from high susceptibility areas. To minimize partial volume effects and contributions of large vessels, the voxel-based analysis on SWI with masked non-brain components should be utilized.

Assessment of Non-permeability of Gd-DTPA for Dynamic Susceptibility Contrast in Human Brain: A Preliminary Study Using Non-linear Curve Fitting (뇌영역의 동적 자화율 대조도 영상에서 Gd-DTPA 조영제의 비투과성 조사: 새로운 비선형 곡선조화 알고리즘 개발의 예비연구)

  • Yoon, Seong-Ik;Jahng, Geon-Ho;Khang, Hyun-Soo;Kim, Young-Joo;Choel, Bo-Young
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.2
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    • pp.103-109
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    • 2007
  • To develop an advanced non-linear curve fitting (NLCF) algorithm for performing dynamic susceptibility contrast study of the brain. The first pass effects give rise to spuriously high estimates of $K^{trans}$ for the voxels that represent the large vascular components. An explicit threshold value was used to reject voxels. The blood perfusion and volume estimation were accurately evaluated in the $T2^*$-weighted dynamic contrast enhanced (DCE)-MR images. From each of the recalculated parameters, a perfusion weighted image was outlined by using the modified non-linear curve fitting algorithm. The present study demonstrated an improvement of an estimation of the kinetic parameters from the DCE $T2^*$-weighted magnetic resonance imaging data with using contrast agents.

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