• 제목/요약/키워드: T1 relaxation time

검색결과 140건 처리시간 0.02초

Microwave and RF Heating for Medical Application under Noninvasive Temperature Measurement Using Magnetic Resonance

  • Nikawa, Yoshio;Ishikawa, Akira
    • Journal of electromagnetic engineering and science
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    • 제10권4호
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    • pp.244-249
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    • 2010
  • Recent development of magnetic resonance imaging (MRI) equipment enables interventional radiology (IVR) as diagnosis and treatment under MRI usage. In this paper, a new methodology for magnetic resonance (MR) scanner to apply not only diagnostic equipment but for treatment one is discussed. The temperature measuring procedure under MR is to measure phase shift of $T_1$, which is the longitudinal relaxation time of proton, for the position inside a sample material with the application of pulsed RF for heating inside the sample as artificial dielectrics. The result shows the possibility to apply MR as temperature measuring equipment and as a heating equipment for applying such as hyperthermia heating modality.

Non-Newtonian Intrinsic Viscosities of Biopolymeric and Nonbiopolymeric Solutions (I)

  • Jang, Chun-Hag;Kim, Jong-Ryul;Ree, Tai-Kyue
    • Bulletin of the Korean Chemical Society
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    • 제8권4호
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    • pp.318-324
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    • 1987
  • Experimental results for viscous flow of poly (${\gamma}$ -methyl L-glutamate) solutions have been published elsewhere. The data of $[{\eta}]^f / [{\eta}]^0$ are expressed by the following equation, $\frac{[{\eta}^f]}{[{\eta}^{\circ}]}=1-\frac{A}{\eta^\circ}{1-\frac{sin^{-1}[{\beta}_2(f/{\eta}_0)\;{e}xp\;(-c_2f^2/{\eta}_0^2kT)]}{{\beta}_2f/{\eta}_0}$ (A1) where $[{\eta}]^f\; and\; [{\eta} ]^0$ are the intrinsic viscosity at shear stress f and zero, respectively, $ A{\equiv}lim\limits_{C{\rightarrow}0}[(1/C)(X_2/{\alpha}_2)({\beta}_2/{\eta}_0)],{\eta}_0$ viscosity of the solvent, ${\beta}_2$ is the relaxation time of flow unit 2, $c_2$ is a constant related to the elasticity of flow unit 2. The theoretical derivation of Eq.(A1) is given in the text. The experimental curves of $[{\eta}]^f / [{\eta}]^0$ vs. log f are compared with the theoretical curves calculated from Eq.(A1) with good results. Eq.(A1) is also applied to non-biopolymeric solutions, and it was found that in the latter case $c_2 = 0.$ The reason for this is explained in the text. The problems related to non-Newtonian flows are discussed.

가압경수로 고준위페기물 처분용기에 대한 크립해석 (Creep Analysis for the Pressurized Water Reactor Spent Nuclear Fuel Disposal Canister)

  • 하준용;최종원;권영주
    • 한국전산구조공학회논문집
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    • 제17권4호
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    • pp.413-421
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    • 2004
  • 본 논문에서는 깊은 지하 500m에 처분된 가압경수로(PWR) 고준위폐기물 처분용기에 지하수압과 벤토나이트 팽윤압이 가해지는 동안 처분용기에 발생하는 크립변형을 예측하기 위하여 처분용기에 대한 구조해석을 수행하였다. 보통 이러한 크립변형은 처분용기에 추가적인 외력이 작용하지 않더라도 처분용기에 작용하는 압력과 내부의 높은 열에 의하여 발생될 수 있다. 처분용 기내부의 열분포의 복잡성 덴 시간의존성으로 인하여 일단 외부 지하수압 및 팽윤압만 고려하여 크립해석을 수행하였다. 이를 위하여 적당한 크립함수를 사용하였으며, 해석은 1억$(10^8)$초 동안 수행하였다. 해석결과 1억초 동안 발생하는 크립 변형률은 매우 작으며 주희 처분용기의 위아래 덮개에 발생함을 알 수 있었다. 그러나 처분용기의 구조강도에 중요한 내부 주철삽입물에는 훨씬 더 작은 미소한 변형률만 발생하여 처분용기에 발생하는 크립변형은 처분용기의 구조적인 안전성에는 큰 영향을 미치지 않음을 알 수 있었다. 해석 초기에 처분용기 내에 급격히 응력이 증가하여 최고치에 도달한 후 잠깐동안 이 응력 값을 유지하다가 그 이 후에는 급격히 응력 값이 감소하는 응력이완현상을 보이고 있기 때문에 발생 응력 측면에서도 전혀 처분용기의 구조적인 안전성에 문제가 없음이 확인되었다.

MR Line Scan Angiography using Spectral Analysis

  • Jung, Kwan-Jin;Ro, Yong-Man;Sim, Bog-Tae;Ra, Jong-Beom;Cho, Zang-Hee
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1989년도 춘계학술대회
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    • pp.27-28
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    • 1989
  • In conventional line scan angiography, flow signal has been enhanced by the time_of_flight effect while the signal from stationary tissues has been suppressed by the saturation rf pulse followed by spoiling gradients. Due to the inhomogeneous rf field and the tissue dependent T1 relaxation time, however, stationary tissues can not be suppressed completely or uniformly, and the remnant stationary signal deteriorates the resultant angiogram. Here, the complete cancellation of stationary tissues is made possible by the spectral analysis of a series of repetitive line images of the same slice. The Fourier transformation of a set of line images results in the spectrum images, where stationary tissues are collected into the dc component while arteries are included in harmonic components because of the variation of the flow velocity and the resultant flow signal in arteries according to the cardiac cycle. The summation of harmonic components excluding the dc component results in the angiogram of arteries with the complete cancellation of stationary tissues.

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스트레스 관리 프로그램이 간호사의 스트레스 지각, 대처유형, 스트레스 반응에 미치는 효과 (The Effect of Stress Management Program on the Perceived stress, Stress response, Ways of Coping of Nurses)

  • 하나선;최정;이용미;임미영;이규은;길숙영;고명숙
    • 간호행정학회지
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    • 제8권1호
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    • pp.31-44
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    • 2002
  • The main purpose of this study was to identify the effect of stress management program on the perceived stress, stress response, ways of coping of nurses.The data were collected from September 22 to December 21, 1997. The subjects were 45 emergency nurses of three university hospital located in seoul ; 25 assigned for the experimental group and 20 for the control group.The stress management program was composed of cognitive training, behavioral training and progressive muscle relaxation. The subjects of the experimental group carried out the 15-minute progressive muscle relaxation according to recorded-tape once a day for 6 weeks. The cognitive and the behavioral training were conducted by the investigator for 5~8 subjects at a time for 9 series, at an interval of 4~5days.The instruments used in the study was the perceived stress scale developed by Levenstein et al.(1993), Symptoms of stress Inventory(1991), and ways of coping scale developed by Lazarus & Folkman(1984).The data were analyzed by SAS program, using descriptive statistics, χ2-test, t-test, paired t-test.The results were as follows :1. The perceived stress of experimental group was lower than that of the control group. However, no significant difference between the two groups was revealed.2. The stress response of experimental group was reduced after stress management program and the stress response of control group was reduced after stress management program. but no significant difference between the two groups was revealed.3. The problem oriented coping of the experimental group was higher than that of the control group, however no significant difference between the two groups was revealed.4. The emotional oriented coping of the experimental group was lower than that of the control group, however no significant difference between the two groups was revealed.

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기판온도에 따른 ITO 박막의 제조 및 특성 (Preparation and characterization of ITO Thin Film By Various Substrate heating temperature)

  • 김성진;박헌균
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 춘계학술대회 초록집
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    • pp.94.2-94.2
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    • 2010
  • Indium tin oxide (ITO) Thin films were grown on Non-alkarai glass Substrates by PVD method and Subsequently Subjected to ($100^{\circ}C-350^{\circ}C$) Thermal Annealing (TA) In Nitr Oxygen ambinent. Most of all, The effect of TA treatment on the structural properties were studied by using X-Ray diffraction and atomic force microscopy, while optical properties were studied by UV-Transmittance measurements. After TA treatment, the XRD spectra have shown an effective relaxation of the residual compressive stress, As a result, XRD peaks increase of the intensity and narrowing of full width at half-maximun (FWHM). In addtion The microstructure, The surface morphology, the optical transmittance changed and improved, and we investigated The effects of temperature, Time and atmosphere during the TA on the structural and electrical properties of the ITO/glass on TA at $300^{\circ}C$. As a results, the films are highly transparent (80%~89%) in visible region. AFM analysis shows that the films are very smooth with root mean square surface roughness 0.58nm -2.75nm thickness film. It is observed that resistivity of the films drcreases T0 $1.05{\times}10^{-4}{\Omega}cmt$ $6.06{\times}10^{-4}{\Omega}cm$, while mobility increases from $152cm^2/vs$ to $275cm^2/vs$.

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향요법마사지의 심리신경면역학적 효과 (Psychoneuroimmunologic Effect of Aromatherapy massage)

  • 이성희
    • 여성건강간호학회지
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    • 제6권2호
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    • pp.305-315
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    • 2000
  • The purpose of this study was to explore the psychoneuroimmunologic effect of aromatherapy massage and to compare the effect with that of massage. This study is designed as a nonequivalent control group pretest-posttest quasi-experimental study and each twenty postpartum mothers volunteered the experimental group and control group. For experimental group, researcher used massage with 2% Jojova oil mixed with Lavender and Rosemary oil (Bush Boake Allen Inc., USA) for 20 minutes, whereas for control group Jojova oil was used as luburicant for massage. Skin temperature was measured with YSI Tele-thermometer(Simpson electric Co., USA) and the concentration of IgA in salivary was analyzed by immunoturbididimetric assay(Cobas INTEGRA, Roche, Swiss) at pre and post test. Also at this time fatigue were measured by Rhoten Fatigue Scale through self-report. The data were analyzed using SAS and hypothesis was tested with unpaired t-test. The results were as follows : 1) Score of fatigue decreased significantly after use of aromatherapy massage. 2) Skin temperature increased significantly after use of aromatherapy massage. 3) Concentration of salivary IgA increased significantly after use of aromatherapy massage. In conclusion, from the standpoint of psychoneuroimmunologic view, the results suggest that aromatherapy massage have greater effect compared with massage and can be effective nursing intervention to enhance relaxation of mind and body in the postpartum mothers.

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FLASH를 이용한 3T 복부검사에 있어서 최적의 T1효과를 위한 적정 Flip Angle (Flip Angle of the Optimal T1 Effect Using FLASH Pulse Sequence at 3T Abdominal MRI)

  • 한재복;최남길
    • 대한방사선기술학회지:방사선기술과학
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    • 제32권1호
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    • pp.101-106
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    • 2009
  • 본 연구는 FLASH 펄스파형을 이용하여 숙임각(flip angle ; FA)변화에 따른 T1 강조영상의 신호강도(signal intensity ; SI)와 대조도 대 잡음비(contrast to noise ratio ; CNR)를 비교함으로써 복부검사에서의 최적의 T1효과를 나타내기 위한 FA를 알아보고자 하였다. 2008년 9월부터 12월까지 본원을 내원하여 복부 MRI 검사를 시행한 환자 20명(남 : 12명, 여 : 8명, 연령 범위 : $28{\sim}63$세, 평균 : 51세)을 대상으로 하였다. 영상 장비는 3Tesla MR scanner(Magnetom Tim Trio, SIEMENS, Germany)였으며, 8 channel body array coil을 사용하였다. 사용된 영상변수는 FLASH 펄스파형과 TR : 120 ms, TE : minimum, FOV : $360{\times}300\;mm$, Matrix : $256{\times}224$, Slice : 6 mm, scan time : 15초로 Breath-hold 기법을 이용하였다. 복부 영상은 물 신호를 동시에 측정하기 위해 관심영역(FOV) 안에 물을 채운 50 ml syringe를 놓고 $10^{\circ}$부터 $90^{\circ}$까지 $10^{\circ}$ 간격으로 FA에 변화를 주면서 얻었다. 획득한 영상은 간(liver), syringe내부의 물(water), 비장(spleen), background의 신호강도(SI)와 대조도 대 잡음비(CNR)를 각각 측정하였으며 신호강도는 관심영역을 설정한 다음 각 부위에서 3번씩 측정하고 그 평균값을 구하였다. 영상 전체의 평가에서는 변이계수(coefficient of variation)를 적용하여 전체영상의 신호강도 균일도를 알아보았고 통계 분석은 SPSS for window version 17.0을 이용하였다. 간(liver)의 신호강도는 $475.54{\pm}81.76$으로 FA $40^{\circ}$에서 가장 높게 나타났으며 syringe내부의 물의 신호는 $475.97{\pm}68.98$로 FA $20^{\circ}$에서 가장 높았으며 FA가 높아짐에 따라 다른 조직의 신호보다 많은 감소를 보였다. 비장의 신호는 $443.02{\pm}55.77$로 FA $30^{\circ}$에서 가장 높은 신호강도를 보였으며 FA가 높아짐에 따라 신호가 감소하였다. 조직의 신호강도에서 Liver vs Water와 Liver vs Spleen은 FA $30^{\circ}$를 제외한 전 구간에서 통계적으로 유의한 차이를 보였고 Water vs Spleen은 FA $60^{\circ}$, FA $70^{\circ}$, FA $80^{\circ}$에서만 유의한 차이를 보였다(p < 0.01). 전체영상의 신호강도는 $175.42{\pm}57.93$으로 FA $10^{\circ}$에서 가장 낮게 나타났으며 FA가 높아짐에 따라 증가하다가 떨어지는 양상을 보였다. 또한 변이계수(coefficient of variation)는 FA $10^{\circ}$와 FA $20^{\circ}$에서 33.02와 31.43으로 가장 높게 나타났다. FA $10^{\circ}$와 FA $20^{\circ}$는 전체영상의 신호강도 균일도가 다소 떨어지는 영상으로 왜곡이 심하게 나타났다. CNR은 liver-water에서 FA $30^{\circ}$에서 12.73으로 가장 낮게 나타났고 FA $10^{\circ}$에서 -46.97, FA $80^{\circ}$에서 29.36으로 가장 높게 나타났다. liver-spleen의 CNR에서는 FA $10^{\circ}$에서 -3.18로 가장 낮게 나타났으며 FA $80^{\circ}$에서 9.65로 가장 높게 나타났다. 결론적으로 FLASH 펄스 파형을 사용한 복부 영상에서 최적의 T1효과를 나타내기 위해서는 FA $80^{\circ}$를 사용하는 것이 유용할 것으로 생각된다.

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Chiller용 냉매 CFC-11과 대체냉매 HCFC-123의 전기장을 사용한 핵비등 열전달 촉진에 관한 연구 (An Experimental Study of Nucleate Boiling Heat Transfer With EHD Technique in CFC-11 and HCFC-123)

  • 곽태희;김주형;정동수;김종보;차태우;한창섭
    • 설비공학논문집
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    • 제6권4호
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    • pp.365-379
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    • 1994
  • Pool boiling experiments were carried out to study the effect of electric field on nucleate boiling heat transfer. CFC-11 and its alternative HCFC-123 were used as working fluids. Boiling on both single tube and a bundle of five tubes was investigated. Heat flux varied from 5 to $25kW/m^2$ while the applied voltage changed from 0 to 1kV. The results showed that at low heat flux where boiling was not present or very weak, electric field-induced forced convection helped increase the heat transfer coefficients of CFC-11 and HCFC-123 significantly(4-15 times increase). However, at higher heat flux, nucleate boiling of CFC-11 which is a highly dielectric fluid, was not affected significantly by the application of electric field. In contrast to CFC-11, even at high heat flux, nucleate boiling of CFC-11 which has a relatively larger electric conductivity than CFC-11, was vigorously increased up to 2-4 times. The additional power required to apply the electric field was 1-2% of the total power consumption by the heater. The increase in overall heat transfer coefficient of evaporators with HCFC -123 was about 40%, suggesting a considerable reduction in evaporator size with EHD technique.

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심근생존능검사 시 가돌리늄 함유량이 높은 조영제의 유용성 (Usefulness of contrast agent involving high gadolium content for myocardial viability assessment)

  • 최관우;손순룡;김태형;한만석;이희주;민정환
    • 한국산학기술학회논문지
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    • 제14권3호
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    • pp.1294-1300
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    • 2013
  • 본 연구는 심근생존능검사 시 가돌리늄 함유량이 높은 조영제(1mmol/mL)를 사용함으로써 대조도대잡음비(CNR)를 높이고, 이로 인한 진단적 가치를 극대화 시키는데 연구의 목적을 두었다. 조사방법은 단위부피당 0.5mmol/mL의 함유량을 가진 기존의 조영제(gadoterate meglumine)를 사용한 284명과 1mmol/mL의 함유량을 가진 새로운 조영제(gadobutrol)를 사용한 120명 등 총 404명의 환자를 연구대상으로, 가돌리늄 함유량에 따른 대조도 차이를 알아보기 위하여 좌심실과 정상심근의 신호강도를 각각 측정한 후 신호대잡음비(SNR)와 CNR을 비교 평가하였다. 연구 결과, 가돌리늄 함유량이 1mmol/mL 조영제 사용 시 SNR은 심근이 25.13%, 심실이 30.74% 높았고, CNR 또한 SNR과 같이 31.29% 높았으며, 통계적으로도 매우 유의하였다. 결론적으로 가돌리늄 함유량이 높은 1mmol/mL 조영제의 사용으로 높은 T1 단축효과를 나타내어 신호강도가 커지고, 이로 인해 대조도 차이가 큰 영상을 얻어 진단적 가치가 높았다. 본 연구는 심장질환이 의심되는 환자에 대한 1mmol/mL 조영제의 유용성을 최초로 증명하여 진단적 가치를 높일 수 있다는 데에 학문적 의의가 있다.