• Title/Summary/Keyword: T-test analysis

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Hypericum Perforatum Decreased Hippocampus TNF-${\alpha}$ and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats

  • El-Bakly, Wesam M.;Hasanin, Amany H.
    • The Korean Journal of Physiology and Pharmacology
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    • v.18 no.3
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    • pp.233-239
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    • 2014
  • The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-${\alpha}$ levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to $17{\alpha}$-ethinylestradiol. Behavioral analysis by measuring immobility time in forced swimming test and open field test, serum and hippocampal corticosterone and TNF-${\alpha}$ along with hippocampal kynurenine/tryptophan ratio were determined in mature ovariectomized rats treated orally either by HP at three different doses 125, 250, and 500 mg/kg/day or by $17{\alpha}$-ethinylestradiol $30{\mu}g/kg/day$ for 30 days. Ovariectomized rats showed significant increase in immobility time in the forced swimming test. Along with elevation in serum and hippocampal TNF-${\alpha}$ and corticosterone levels associated with significant increase in hippocampal kynurenine/tryptophan ratio. Immobility time in the forced swimming test was decreased in rats treated by different doses of HP in a dose dependent manner and $17{\alpha}$-ethinylestradiol with no concomitant changes in the open field test. Only Rats treated with HP exhibited significant decrease in the elevated serum and hippocampal TNF-${\alpha}$ and corticosterone, which couldn't explain the associated insignificant effect on hippocampaus kynurenine/tryptophan ratio in comparison to ovariectomized untreated rats. It is concluded that increased tryptophan metabolism toward kynurenine secondary to elevated corticosterone and TNF-${\alpha}$ might be one of the pathohphysiological mechanisms that could explain depression like state observed in this rat model. Further, the observed attenuating effect of HP on TNF-${\alpha}$ and corticosterone could contribute in its antidepressant effect in this animal model by other ways than their effects on tryptophan-kynurenine metabolism pathway.

The Effect of MMTIC Group Counseling Program on Self-esteem of Elementary School Students (MMTIC을 활용한 집단상담이 초등학생의 자아존중감에 미치는 효과)

  • Song, Seon-Suk
    • 한국초등상담교육학회:학술대회논문집
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    • 2004.01a
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    • pp.271-294
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    • 2004
  • The purpose of this study was to examine the effects of MMTIC group counseling program on self-esteem of elementary school students. The hypothesis was that the self-esteem test scores of experimental group would be significantly higher than those of control group. The subjects were the twenty 5th graders sampled from the 66 5th graders of D Elementary School in Boryeong City based on self-esteem test scores. The 10 subjects were randomly assigned experiment group and others were assigned control group. The self-esteem test by Mun, Yong Woo (2002) modified from the measurement of Kim, Heui Hwa (1989) was administrated as pre and post test. The experimental group has experienced MMTIC group counseling program. On the other hand, the control group has not been given any advice during the counseling periods. The counseling was once a week at two o'clock in the afternoon for ten weeks from the eleventh of May to sixteenth of July in 2003. Each counseling session lasted sixty to eighty minutes. The group counseling program, which has been used in this research, has been adapted to the level of elementary students with the consideration of MBTI and MMTIC Workshop in reference to a few theses related to MMTIC development program (Jung, Gyeong Yeon, 2001: Gang, Jae Jeong, 2002; Lee, Jae Mo 2002). The results were analysed by t-test. These statistics with a quantitative result has been supplemented with a qualitative analysis by a questionnaire and the descriptions of impression of subjects of experimental group. The results of this research was that the analyses of the questionnaire and a description of their impression have shown that the counseling has had an significantly impact on their understanding themselves and others. In particular, this program has been positively conducive to receptive relationships to others. In conclusion, the MMTIC group counseling program has helped elementary students I understand themselves and others, increase receptive competence, encourage their confidence, improve personal relationships and enhance their adaptation to their school life. It suggests that this program has a feasible effect on children's sense of self-esteem.

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Analysis of Muscular Activity of Tibialis Anterior Muscle and Gastrocnemius Muscle in Functional Reach Test of Elderly According to Different Surfaces (기능적 팔 뻗기 시 지면에 따른 앞정강근과 장딴지근의 근활성도 비교)

  • Park, Jeong-Seo;Nam, Yeon-Kyeong;Kim, Moon-Jeong;Yoon, Se-Won
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.9 no.2
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    • pp.25-30
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    • 2011
  • Purpose : This study aims to examine the changes of muscle activity of the tibialis anterior muscle and the gastrocnemius muscle on the ground and unstable ground for functional reach test. Methods : This study chose 24 elderly men and 24 elderly women who could walk independently, reach their arm over 25 cm, show shoulder joint $90^{\circ}$ flexion, had no operations on lower limb joints, and don't take medication affecting the ability to keep balance. Muscular activity of the tibialis anterior muscle and the gastrocnemius muscle was measured using functional reach test and electromyogram. Functional reach test was conducted at a total of four sections, 0cm, 15cm, 20cm, and 25cm. Results : It was known that the gastrocnemius muscle was used more than the tibialis anterior muscle to keep balance and the elderly with good balance ability showed no great change of muscular activity on both the stable and unstable ground. Conclusion : It was found that the subjects used their gastrocnemius muscle more and lower limbs of frequently used parts to keep their balance. As the elderly have good balance ability, they showed no great change of muscular activity on both the stable and unstable ground.

Correlations among Respiratory Function, UPDRS and Senior Fitness in Parkinson's Disease Patients (파킨슨병환자의 호흡기능, UPDRS 및 Senior Fitness의 관련성)

  • Kang, Dong-Yeon;Cheon, Sang-Myung;Cheon, Sang-Myung;Lee, Kyung-Soon;Kim, Kyoung
    • The Journal of Korean Physical Therapy
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    • v.26 no.2
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    • pp.48-55
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    • 2014
  • Purpose: The purpose of this study was to examine correlations among UPDRS, respiratory function, and senior fitness and to investigate the effects of restrictive respiratory function on these factors in Parkinson's disease patients. Methods: Subjects (n=25, Hoehn & Yahr (H&Y) stage: 2-3, $69.3{\pm}5.9$ yrs) from D Hospital Parkinson's Disease Center at Busan metropolitan area in the Republic of Korea volunteered for this study. They performed the pulmonary function test, UPDRS, and the senior fitness test. SPSS 18.0 was used for analysis of data, and the collected data were analyzed using Pearson's correlation coefficient (n=25). In addition, Independent t-test was used for determination of differences between two groups (between the normal pulmonary function group (n=10) and the restrictive pulmonary function group (n=10)). Results: Forced vital capacity (FVC (L)) showed significant negative correlation (r=-0.44, p<0.05) with H&Y stage in Parkinson's disease patients, and chair stand showed significant negative correlations (r=0.41, 0.43, 0.42, p<0.05) with FVC (L), FVC (%), and FEV1 (L). FVC (%) showed significant positive correlations (r=0.44, r=0.44, p<0.05) with right and left back scratch. In addition, the restrictive respiratory function group showed significantly lower FVC (%) (p<0.01) and was significantly slower (p<0.05) in the 8-foot up-and-go test than the normal respiratory function group. Conclusion: In conclusion, these results suggest that restrictive respiratory function in PD was related to H&Y stage. In addition, agility of PD patients was lower in the restrictive respiratory function group than in the normal function group.

Development of Standard Test Specification for Hiking Stick (등산스틱 시험규격 개발 연구)

  • Kil, S.K.;Kim, J.H.;Kim, T.W.;Lee, S.C.;Hwang, J.H.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.9 no.4
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    • pp.309-317
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    • 2015
  • In this paper, we proposed the standard test specification for safety and function of hiking stick for the elderly. We have concluded nine factors representing specification of hiking stick through analysis of hiking patents and research papers, products survey of business market, case studies for damaged hiking stick and expert surveys. To test the factors, we designed three different kinds of apparatus to examine twist resistance, stick and tip durability and stick straightness. The sample of hiking sticks purchased from market based on Naver sales ranking top to fifteenth. As a result, we concluded six-standard test specification based on eccentric load, adjustable parts load, hand strap load, basket load, tip load and pull load of hiking stick.

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Performance Evaluation of RAP and WMA Mixtures Located in MN/Road Test Cells through Air Voids Analyses (MN/Road 시험포장 구간내의 공기량 측정 및 결과값 분석을 통한 RAP 및 저온 아스팔트(WMA) 혼합물의 특성 평가)

  • Moon, Ki Hoon;Falchetto, Augusto Cannone;Jeong, Jin Hoon
    • International Journal of Highway Engineering
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    • v.16 no.4
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    • pp.63-74
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    • 2014
  • PURPOSES: This research is to evaluate the mechanical performance of different types of Hot Mix Asphalt (HMA) pavement cells prepared for MN/Road field testing section through an extensive experimental analysis of air voids and simple statistical evaluation tools (i.e. hypothesis test). METHODS: An extensive experimental work was performed to measure air voids in 82 asphalt mixture cores (238 samples in total) obtained from nine different types of road cell located in MN/Road testing field. In order to numerically and quantitatively address the differences in air voids among the different test Cells built in MN/Road, a simple statistical test method (i.e. t-test) with 5% significance was used. RESULTS: Similar trends in air voids content were found among the mixtures including conventional HMA, Reclaimed Asphalt Pavement (RAP) and Warm Mix Asphalt (WMA) combined with taconite aggregate this provides support to the use of RAP and WMA technology in the constructions of asphalt pavement. However, in case of acid modified HMA mixtures, significant differences in air void content were observed between on the wheel path and between wheel path location, which implies negative performances in rutting and thermal cracking resistances. Conclusions : It can be concluded that use of RAP and WMA technology in the construction of conventional asphalt pavement and the use of PPA (Poly Phosphoric Acid) in combinations with SBS (Styrene Butadiene Styrene) in asphalt binder production provide satisfactory performance and, therefore, are highly recommended.

Effects of Anger and Entrapment on Psychological Health of High School Boys: Focused on the Mediating Effects of Social Support (남자 고등학생의 분노 및 속박감이 정신건강에 미치는 영향: 지각된 사회적 지지의 매개효과를 중심으로)

  • Yang, Sun Yi;Oh, Yun Hee
    • Child Health Nursing Research
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    • v.23 no.4
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    • pp.429-439
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    • 2017
  • Purpose: The aim of this study was to identify the status of psychological health among boys in high school and to examine the mediating effects of social support on the relationship between anger and entrapment on psychological health. Methods: The participants in this study were 193 high school boys from Jeju. Measurements included state-trait anger expression inventory, entrapment scale, student social support scale, and questionnaires to assess mental and physical health. Data were analyzed using independent t-test, one-way ANOVA, $Scheff{\acute{e}}$ test, Pearson correlation coefficient, simple and multiple regression techniques with the SPSS 21.0. Mediation analysis was performed with the Baron and Kenny's method, and Sobel test. Results: Mean scores for anger experience, entrapment, social support, and psychological health were $29.81{\pm}7.34$, $34.09{\pm}16.33$, $45.75{\pm}7.02$, $22.51{\pm}9.91$, respectively. There was a significant correlation between anger experience and psychological health. Entrapment was significantly correlated with psychological health. Social support showed partial mediating effects in the relationship between anger experience and psychological health (Sobel test: Z=54.18. p<.001). Social support showed partial mediating effects in the relationship between entrapment and psychological health (Sobel test: Z=2.24. p=.025). Conclusion: The results indicate a need to develop social support programs for boys in high school.

PULPAL ANESTHETIC EFFECT OF INFERIOR ALVEOLAR NERVE BLOCK AND GOW-GATES TECHNIQUE (하악공 전달마취법과 Gow-Gates법의 치수마취 효과)

  • Ahn, Sik-Hwan;Kim, Sung-Kyo
    • Restorative Dentistry and Endodontics
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    • v.22 no.1
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    • pp.278-290
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    • 1997
  • The purposes of this study were to evaluate and compare the pulpal anesthesia induced by an inferior alveolar nerve block and that by Gow-Gates technique, and to investigate the relationship between pulpal anesthesia and intraoral soft tissue responses. After one side of mandibule was anesthetized with inferior alveolar nerve block or Gow-Gates technique using 2 % lidocaine with 1 : 100,000 epinephrine in 19 volunteers of ages between 24 and 29 (16 males and 3 females, average age 25.9 yrs.), electric pulp tests were done on the canine teeth of the anesthetized side and contralateral one before, at 1 min, continued at every 5 minutes until 60 min, and every 10 minutes until 100 min after completion of local anesthetic injection. Degree of pulpal anesthesia was classified as anesthetic failure, possible anesthesia and complete anesthesia by the criteria based on the thresholds to electric pulp test of contralateral canine and the currents of the electric pulp tester. Subjective signs on the lower lip and tongue were checked and prick-pin tests were done on the buccal gingiva of the first molar, buccal and lingual gingiva of the canine tooth at 5, 10 and 20 min after the completion of anesthetic injection. Thresholds to electric pulp test, degree of pulpal anesthesia and relationship between the pulpal anesthesia and soft tissue responses were analyzed with SPSS, paired t-test, Wilcoxon matched-pairs signed-ranks test and correlation analysis. The results were as follows : No significant differences were found in the peak thresholds to electric pulp test, in the induction time to it and in the depth of pulpal anesthesia between inferior alveolar nerve block and Gow-Gates technique (p>0.05). There was no significant relationship between pulpal anesthesia and soft tissue responses in both inferior nerve block and Gow-Gates technique.

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The effect of different fiber reinforcements on flexural strength of provisional restorative resins: an in-vitro study

  • Kamble, Vaibhav Deorao;Parkhedkar, Rambhau D.;Mowade, Tushar Krishnarao
    • The Journal of Advanced Prosthodontics
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    • v.4 no.1
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    • pp.1-6
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    • 2012
  • PURPOSE. The aim of this study was to compare the flexural strength of polymethyl methacrylate (PMMA) and bis-acryl composite resin reinforced with polyethylene and glass fibers. MATERIALS AND METHODS. Three groups of rectangular test specimens (n = 15) of each of the two resin/fiber reinforcement were prepared for flexural strength test and unreinforced group served as the control. Specimens were loaded in a universal testing machine until fracture. The mean flexural strengths (MPa) was compared by one way ANOVA test, followed by Scheffe analysis, using a significance level of 0.05. Flexural strength between fiber-reinforced resin groups were compared by independent samples t-test. RESULTS. For control groups, the flexural strength for PMMA (215.53 MPa) was significantly lower than for bis-acryl composite resin (240.09 MPa). Glass fiber reinforcement produced significantly higher flexural strength for both PMMA (267.01 MPa) and bis-acryl composite resin (305.65 MPa), but the polyethylene fibers showed no significant difference (PMMA resin-218.55 MPa and bis-acryl composite resin-241.66 MPa). Among the reinforced groups, silane impregnated glass fibers showed highest flexural strength for bis-acryl composite resin (305.65 MPa). CONCLUSION. Of two fiber reinforcement methods evaluated, glass fiber reinforcement for the PMMA resin and bis-acryl composite resin materials produced highest flexural strength. Clinical implications. On the basis of this in-vitro study, the use of glass and polyethylene fibers may be an effective way to reinforce provisional restorative resins. When esthetics and space are of concern, glass fiber seems to be the most appropriate method for reinforcing provisional restorative resins.

Factors influencing the ambulatory status in Hemiplegia with Intracerebral Hemorrhage after rehabilitation (뇌출혈으로 인한 편마비 환자의 재활치료 후 보행능력에 영향을 주는 요인)

  • Kim, Chan-Kyu;Kim, Kweon-Young
    • Journal of Korean Physical Therapy Science
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    • v.6 no.2
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    • pp.1007-1017
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    • 1999
  • The purpose of this study was to evaluate the factors influencing the ambulatory status in hemiplegia with intracerebral hemorrhage after rehabilitation. Thirty patients with stroke who was admitted in the Chosun University Hospital, between from January 1st' 1998 and December 31st' 1998, were included in this study. The following variables as a potential predictors for ambulation were evaluated at treatment of the stroke onset; 1) general characteristics including age and sex, and 2) clinical characteristics including frequency and onset time of the stroke, affected side, duration of the treatment, time interval between onset and rehabilitation, manual muscle test of paretic limb, sitting and standing balance, proprioception, perception, cognitive function. We compared and analyzed the these variables to the two type of ambulatory status at the time of the discharge by Modified Barthel Index, independent, dependent. The data were analyzed by student t-test, Fisher-exact test, Mann Whitney-U test, $X^{2}$-test, correlation analysis(spearman's). The results were as follows; 1. Were no significantly inflenced independent ambulatory status among general characteristics. 2. Frequency of the stroke and proprioception (p<0.05), muscle strength of the lower limb, cognitive function and standing balance (p<0.01), perception and sitting balance (p<0.001) were significantly inflenced independent ambulatory status among clinical characteristics. 3. Independent Variable correlated with the ambulatory status were muscle strength of the lower limb, proprioception and sitting balance (p<0.05), standing balance, frequency of the stroke, perception and cognitive function (p<0.01). Therefore the muscle strength of the lower limb, proprioception, sitting balance, standing balance, frequency of the stroke, perception, cognitive function were the most significant influencing factors of ambulatory status after rehabilitation.

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