• 제목/요약/키워드: T-factor

검색결과 7,135건 처리시간 0.046초

Corrigendum to: Protective effects of lutein against vancomycin-induced acute renal injury in mice via upregulation of peroxisome proliferator-activated receptor gamma/nuclear factor erythroid 2-related factor 2 and inhibition of nuclear factor-kappaB/caspase 3

The Effect of Fashion Product Consumers' Need for Uniqueness on their Criteria of Clothing Selection and Switching Intentions

  • Park, Soojin;Park, Sookyeong
    • 패션비즈니스
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    • 제20권3호
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    • pp.54-67
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    • 2016
  • The purpose of this study was to investigate the The effect of fashion consumer's need for uniqueness in their clothing purchase behavior and switching intention. A total of 332 cases were included as the subjects of this study and a survey method was used. The data were analyzed by factor analysis, reliability analysis, t-test and multiple regression analysis using the SPSS 22.0 statistical program. The results were as follows. 1. The 3 dimensions (creative choice, unpopular choice, and avoidance of similarity) were extracted from the consumer's need for uniqueness and consumer divided high uniqueness group, middle uniqueness group, low uniqueness group. 2. The 3 factor (esthetic, functional, practical) were extracted from the clothing selection criteria. The three group had a significant difference in clothing selection and switching intention. Aesthetic factor and practical factor were the highest in high uniqueness group. 3. The need for uniqueness has influence on the aesthetic factor and practical factor. The creative choice factor had positive effect on the aesthetic and practical factor, yet unpopular choice factor had negative effect on the practical factor. The need for uniqueness and aesthetic factor has positive influence on brand switching intentions. 4. There was difference in unpopular choices factor by gender. A monthly average expenditure on fashion products had a significant difference in three kind of need for uniqueness. Results of this study provide a basis understand need for uniqueness and their effect on consumer behavior.

소방공무원의 직무질환에 관한 연구 (A Study on Occupational Diseases of Fire Officials)

  • 조광래
    • 시큐리티연구
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    • 제61호
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    • pp.109-135
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    • 2019
  • 본 연구는 소방공무원의 직무질환(진료건수)에 대한 시계열 분석 등 기술적 탐색 연구를 진행하는데 그 목적이 있다. 구체적인 연구결과는 다음과 같다. 첫째, 소방공무원의 직무질환에 대한 평균추이는 ① 내과 질병은 12월이 9.24%로 가장 높고, 2월이 7.76%로 가장 낮고, ② 이비인후과 질병은 12월이 9.29%로 가장 높고, 8월이 6.74%로 가장 낮으며, ③ 피부과 질병은 7월이 10.03%로 가장 높고, 1월과 2월이 7.35%로 가장 낮고, ④ 외과 질병은 11월이 10.38%로 가장 높고, 2월이 5.62%로 가장 낮으며, ⑤ 정형외과 질병은 3월이 9.69%로 가장 높고, 11월이 7.52%로 가장 낮고, ⑥ 신경외과 질병은 4월이 9.33%로 가장 높고, 2월이 6.82%로 가장 낮으며, ⑦ 재활의학과 질병은 12월이 9.47%로 가장 높고, 10월이 7.06%로 가장 낮고, ⑧ 정신건강의학과 질병은 12월이 9.93%로 가장 높고, 5월이 6.51%로 가장 낮은 것으로 나타났다. 둘째, 소방공무원의 직무질환에 대한 계절분해는 ① 내과 질병은 1.075(S) × 189.355(T·C) × 1.174(R) = 238.975(F), ② 이비인후과 질병은 1.023(S) × 69.605(T·C) × 1.040(R) = 74.000(F), ③ 피부과 질병은 1.002(S) × 73.088(T·C) × 0.874(R) = 64.000(F), ④ 외과 질병은 1.099(S) × 27.229(T·C) × 0.669(R) = 20.000(F), ⑤ 정형외과 질병은 1.115(S) × 73.182(T·C) × 1.213(R) = 99.000(F), ⑥ 신경외과 질병은 0.993(S) × 27.836(T·C) × 1.303(R) = 36.000(F), ⑦ 재활의학과 질병은 1.029(S) × 62.417(T·C) × 1.152(R) = 74.000(F), ⑧ 정신건강의학과 질병은 1.210(S) × 8.781(T·C) × 1.035(R) = 11.000(F) 등으로 나타났다.

스텐트의 구조 및 기계적인 반응에 대한 최적인자 도출과 유한요소해석법을 통한 검증 (Deduction and Verification of Optimal Factors for Stent Structure and Mechanical Reaction Using Finite Element Analysis)

  • 전동민;정원균;김한기;김상호;신일균;장홍석;서태석
    • 한국의학물리학회지:의학물리
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    • 제21권2호
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    • pp.201-208
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    • 2010
  • 최근 내시경의 기술발전과 더불어 수술의 편의성, 회복시간의 단축, 환자의 고통감소 등의 효과를 위하여 스텐트가 개발되고 있다. 이를 위해 스텐트 구조와 기계적인 반응에 대한 최적의 인자를 찾고 유한요소해석법을 통해 최적 조건임을 검증하였다. 현재 상용화된 제품들 중 선호도가 높은 Zilver (Cook, Bloomington, Indiana, USA)와 S.M.A.R.T (Cordis, Bridgewater Towsnhip, New Jersey, USA) 모델을 분석하였고, 스텐트의 기계적 요소에 영향을 미치는 중요인자를 도출하기 위해 다구치 요인분석으로 배열한 다음, 유한요소해석법으로 유연성과 팽창성을 찾아보았다. 또한 반응표면분석의 중심합성법을 이용하여 최적조건에 알맞는 중요인자를 도출하였고, 이를 고려하여 최적설계를 하였다. 본 연구의 결과, 다구치 요인분석을 통한 유연성 평가와는 다르게 팽창력 평가에서는 최적조건을 만족시키는 인자를 찾을 수 없었다. 반응표면분석법의 중심합성법으로 수행한 결과, 스텐트의 유연성에 대한 중요인자는 스텐트의 두께(T), 단위넓이(W)이고, 팽창력에 대한 중요인자는 스텐트의 두께(T)로 도출되었다. 반응면을 통한 중요인자에서 유연성에 대한 것은 두께(T), 단위넓이(W)로 도출되나, 팽창력의 경우에는 다른 중요인자가 있는 것으로 나타났다. 반응표면분석의 중심합성법을 이용하여 최적조건에 부합한 중요인자는 T=0.17, W=0.09의 결과를 보였으며 유연성과 팽창력이 뛰어나 설계요구조건을 충족하였다. 최근에 유한요소 해석법을 이용한 스텐트의 기계적 특성을 평가하기 위한 연구는 상당량 진행되어 왔다. 하지만 체계적인 실험계획법을 적용하여 스텐트의 최적조건을 도출하여 시간 및 비용을 줄이는 설계방법에 대한 연구는 드물다. 본 연구에서는 스텐트를 설계하는데 있어서 세계적으로 검증된 방법인 다구치 요인분석과 반응표면분석법의 중심합성법을 적용하여 최적조건을 도출하고 유한요소해석을 통해 검증함으로써 실제 시제품을 제작하여 발생하는 시간 및 비용을 절감할 수 있었다. 이러한 체계적인 실험계획법과 유한요소해석을 스텐트 설계단계에 적용함으로써 산업체의 스텐트 개발 기간 및 예산 절감 등 경제적 개발에 많은 도움이 될 수 있을 것이다.

한전 765 KV 송전선로 전선선정 검토의 기본 방향 (The conception of conductor selection for KEPCO 765 kV T/L.)

  • 구본묵;오창효;박영신
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1994년도 하계학술대회 논문집 C
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    • pp.1505-1508
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    • 1994
  • Lately in KEPCO, the power plant capacity has increasingly become larger than before and it has become difficult to get R.O.W for T/L. Therefore KEPCO decided to increase its system voltage level from 345kV to 765kV. By doing this, KEPCO would like to expand its transmission capability by less T/L route. In 765kV system, we should consider various kinds of environmental impacts that can be neglected in lower voltage level. These environmental impacts are very important factor in T/L design. That can be changed greatly according to the selected conductor. And also conductor selection has relation with the economy of T/L construction directly. This paper deals with some general factors to be considered and basic principles about the conductor and ground wire selection for 765KV T/L with referring to the experiences of foreign utilities.

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구강편평세포암종 환자에서의 혈액 점도와 혈액 변형성 변화에 대한 연구 (CHANGE OF BLOOD VISCOSITY AND DEFORMABILITY IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS)

  • 윤필영;명훈;이종호;정필훈;김명진
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제30권3호
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    • pp.181-185
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    • 2004
  • Malignant tumor have hypoxic cell fraction, which makes radio-resistant and hypoxia in tumor is a result from the blood flow decrease caused by increase in blood flow resistance. Blood viscosity increase is major factor of increased blood flow resistance and it could be attributed to the decrease in blood deformability index. For the evaluation of the change of blood viscosity and blood deformability in oral squamous cell carcinoma, we perform the test of the change of those factors between the normal control group and oral squamous cell carcinoma cell patient group. Relative viscosity measured against distilled water was $5.25{\pm}0.14$ for normal control group, and $5.78{\pm}0.26$ for the SCC patient group and there was statistical significance between the groups. However, there was no significant difference between the groups in blood viscosity between the groups by tumor size (T1+T2 vs T3+T4). Also, there was no significant difference between the normal control group and SCC patient group in blood deformability index and between the groups by tumor size (T1+T2 vs T3+T4). Increase in blood viscosity was confirmed with this study and it can be postulated that modification blood viscosity might contribute to decrease of hypoxia fraction in oral squamous cell carcinoma, thus improve the effect of radiotherapy and it can be assumed that the main factor of blood viscosity increase is not decrease of blood deformability in oral squamous cell carcinoma.

A Lower T1 Slope as a Predictor of Subsidence in Anterior Cervical Discectomy and Fusion with Stand-Alone Cages

  • Lee, Su Hun;Lee, Jun Seok;Sung, Soon Ki;Son, Dong Wuk;Lee, Sang Weon;Song, Geun Sung
    • Journal of Korean Neurosurgical Society
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    • 제60권5호
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    • pp.567-576
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    • 2017
  • Objective : Preoperative parameters including the T1 slope (T1S) and C2-C7 sagittal vertical axis (SVA) have been recognized as predictors of kyphosis after laminoplasty, which is accompanied by posterior neck muscle damage. The importance of preoperative parameters has been under-estimated in anterior cervical discectomy and fusion (ACDF) because there is no posterior neck muscle damage. We aimed to determine whether postoperative subsidence and pseudarthrosis could be predicted according to specific parameters on preoperative plain radiographs. Methods : We retrospectively analyzed 41 consecutive patients (male : female, 22 : 19; mean age, $51.15{\pm}9.25years$) who underwent ACDF with a stand-alone polyether-ether-ketone (PEEK) cage (>1 year follow-up). Parameters including SVA, T1S, segmental angle and range of motion (ROM), C2-C7 cervical angle and ROM, and segmental inter-spinous distance were measured on preoperative plain radiographs. Risk factors of subsidence and pseudarthrosis were determined using multivariate logistic regression. Results : Fifty-five segments (27 single-segment and 14 two-segment fusions) were included. The subsidence and pseudarthrosis rates based on the number of segments were 36.4% and 29.1%, respectively. Demographic data and fusion level were unrelated to subsidence. A greater T1S was associated with a lower risk of subsidence (p=0.017, odds ratio=0.206). A cutoff value of T1S<$28^{\circ}$ significantly predicted subsidence (sensitivity : 70%, specificity : 68.6%). There were no preoperative predictors of pseudarthrosis except old age. Conclusion : A lower T1S (T1S<$28^{\circ}$) could be a risk factor of subsidence following ACDF. Surgeons need to be aware of this risk factor and should consider various supportive procedures to reduce the subsidence rates for such cases.

Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group

  • Park, Jin Woo;Choi, Ja Sung;Han, Ki Joon;Lee, Sang Heun;Kim, Eui Joo;Cho, Jae Hee
    • The Korean journal of internal medicine
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    • 제33권6호
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    • pp.1103-1110
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    • 2018
  • Background/Aims: Several epidemiological studies have validated the association of interleukin gene polymorphisms with acute pancreatitis (AP) in different populations. However, there have been few studies in Asian ethnic groups. We aimed to investigate the relationships between inflammatory cytokine polymorphisms and AP as pilot research in a Korean ethnic group. Methods: Patients who had been diagnosed with AP were prospectively enrolled. DNA was extracted from whole blood, and DNA sequencing was subsequently performed. Single-nucleotide polymorphisms (SNPs) of the interleukin $1{\beta}$ (IL1B), interleukin 1 receptor antagonist (IL1RN), and tumor necrosis factor ${\alpha}$ (TNFA) genes of patients with AP were compared to those of normal controls. Results: Between January 2011 and January 2013, a total of 65 subjects were enrolled (40 patients with AP vs. 25 healthy controls). One intronic SNP (IL1RN -1129T>C, rs4251961) was significantly associated with the risk of AP (odds ratio, 0.304; 95% confidence interval, 0.095 to 0.967; p = 0.043). However, in our study, AP was not found to be associated with polymorphisms in the promoter regions of inflammatory cytokine genes, including IL1B (-118C>T, c47+242C>T, +3954C/T, and -598T>C) and TNFA (-1211T>C, -1043C>A, -1037C>T, -488G>A, and -418G>A). Conclusions: IL1RN -1129T>C (rs4251961) genotypes might be associated with a significant increase of AP risk in a Korean ethnic group.

쥐에서 허혈-재관류 소장 손상에 대한 담관결찰 및 Insulin-like Growth Factor-I의 영향 (Bile Duct Ligation and Insulin-like Growth Factor-I on the Ischemia-Reperfusion Injury of the Small Bowel)

  • 차제선;이명덕
    • Advances in pediatric surgery
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    • 제3권2호
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    • pp.98-107
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    • 1997
  • To determine whether bile juice exclusion can prevent the mucosal damage, and Insulin-like growth factor-I can promote mucosal regeneration in ischemia-reperfusion injury of the bowel, 39 weanling rats with 10 cm of Thiry-Vella loop were studied. Animal groups were; Control, BL(common bile duct ligation), IGF{insulin-like growth factor-I(IGF-I) infusion} and IGF-BL(combined treatment). IGF-I(1.5 mg/kg/day) was continuously delivered through a subcutaneously implanted miniosmotic pump. After 15 minutes of superior mesenteric artery clamping, a tissue specimen(P) was taken after 30 minutes of reperfusion. Intestinal continuity was restored to allow oral feeding. A specimen of main tract(M) and another of the Thiry-Vella loop(T) were collected for histomorphometry after 48 hours of reperfusion and free feeding. Villus size ratio(VSR), crypt depth(CD), crypt-depth/villus-height ratio(CVR) and injury score(IS) were measured in 15 consecutive villi. The postoperative mortalities of bile duct ligation groups(BL and IGF-BL) were higher than those of other groups. In control group, VSR of M was lower(P<0.05) than P or T, but not in the other groups. VSR of M in control was lower than those in other groups. CD of T in control, IGF and IGF-BL group were higher than those of M. CD of M and T showed gradual increments from control, IGF and IGF-BL group, respectively. CVR of M and T in IGF group were higher than those in control. CVR in IGF-BL group, T was higher than M, and M was higher than P. About IS, M of BL($20.1{\pm}2.5$) and IGF-BL($20.9{\pm}3.3$) groups were significantly lower than that of control($32.4{\pm}2.5$). These results suggest that the exclusion of bile juice reduces the severity of the reperfusion injury of the mucosa, by inability to activate pancreatic enzymes and IGF-I stimulates mucosal regeneration in injured bowel, and the effect is potentiated by bile juice exclusion.

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식물성 에스트로겐이 MC3T3-El 골아세포의 성장과 Insulin-like Growth Factor-1(IGF-1)생성에 미치는 영향 (Effects of Phytoestrogen on Cell Growth and Insulin-like Growth Factor-I (IGF-I) Production in MC3T3-El Cells)

  • 권지영;남택정
    • 한국식품영양과학회지
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    • 제34권6호
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    • pp.743-749
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    • 2005
  • 식물성 에스트로겐은 에스트로겐의 대체물질로서 골 형성을 촉진하며, 다른 부작용 없이 폐경기 이후 여성의 골다공증 예방에 효과적인 물질로 주목받고 있다. 본 연구에서는 식물성 에스트로겐의 골 형성과 관련된 생리학적 기능을 확인하고자 식물성 에스트로겐인 genistein, daidzein 및 resveratrol을 각각 $10^{-5}$ M 농도로 세포배양액 에 첨가하여 MC3T3-El 골아세포의 증식과 성장에 미치는 효과를 검토 하였다 그 결과 이들은 에스트로겐인 $17\beta$-estradiol과 마찬가지로 MC3T3-El 골아세포의 증식과 성장을 향상시켰으며, daidzein과 resveratrol의 효과는 genistein의 효과보다 큰 것으로 나타났다 골 형성 정도를 판단하는 생화학적 지표로 활용되고 골아세포의 증식과도 밀접한 관계를 가지는 alkaline phosphatase(ALP) 활성 또한 genistein, daidzein 및 resveratrol에 의해 증가하였다. 에스트로겐은 세포성장인자인 IGF-I의 국소적 생산과 분비를 촉진하며 간접적으로 골 대사 촉진 효과를 유도해낼 수 있다고 보고되어 있었지만 식물성 에스트로겐의 투여에 의해 IGF-I의 농도가 증가하였다는 보고는 없었다. 그러나 본 실험 결과, 식물성 에스트로겐인 genistein, daidzein 및 resveratrol은 IGF-I의 단백질과 mRNA 수준을 증가시키는 것으로 나타났다. 이상의 연구결과들은 식물성 에스트로겐의 골 형성 촉진 효과를 증명하는 것으로서 이들의 유용한 약리학적 기능을 뒷받침하는 하나의 근거로 활용될 수 있으리라 사료된다.