• Title/Summary/Keyword: T-factor

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Expression of vascular endothelial growth factor in oral squamous cell carcinoma

  • Kim, Seok-Kon;Park, Seung-Goo;Kim, Kyung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.41 no.1
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    • pp.11-18
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    • 2015
  • Objectives: The goal of this study was to determine the correlation of clinicopathological factors and the up-regulation of vascular endothelial growth factor (VEGF) expression in oral squamous cell carcinoma. Materials and Methods: Immunohistochemical staining of VEGF and quantitative real-time polymerase chain reaction (RT-PCR) of VEGF mRNA were performed in 20 specimens from 20 patients with oral squamous cell carcinoma and another 20 specimens from 20 patients with carcinoma in situ as a controlled group. Results: The results were as follows: 1) In immunohistochemical study of poorly differentiated and invasive oral squamous cell carcinoma, high-level staining of VEGF was observed. Significant correlation was observed between immunohistochemical VEGF expression and histologic differentiation, tumor size of specimens (Pearson correlation analysis, significance r>0.6, P<0.05). 2) In VEGF quantitative RT-PCR analysis, progressive cancer showed more VEGF expression than carcinoma in situ. Paired-samples analysis determined the difference of VEGF mRNA expression level between cancer tissue and carcinoma in situ tissue, between T1 and T2-4 (Student's t-test, P<0.05). Conclusion: These findings suggest that up-regulation of VEGF may play a role in the angiogenesis and progression of oral squamous cell carcinoma.

A new bridge-vehicle system part II: Parametric study

  • Chan, Tommy H.T.;Yu, Ling;Yung, T.H.;Chan, Jeffrey H.F.
    • Structural Engineering and Mechanics
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    • v.15 no.1
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    • pp.21-38
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    • 2003
  • The formulation of a new bridge-vehicle system using shell with eccentric beam elements has been introduced in a companion paper (Part I). The new system takes into account of the contribution of the twisting and pitching modes of vehicles to the bridge responses. It can also be used to study the dynamic transverse load distribution of a bridge. This paper presents a parametric study on the impact induced by one vehicle or multi-vehicle running across a bridge using the proposed model. Several parameters were considered as variables including the mass ratio, the speed parameter, the frequency ratio and the axle spacing parameter to investigate their effects on the impact factor. A total number of 189 cases were carried out in this parametric study. Within the realistic range of vehicle considered, the maximum impact factors could be 2.24, 1.78 and 1.49 for bridges with spans 10 m, 20 m and 30 m respectively.

Estimating Economic Service Life of Assets by Using National Wealth Statistic (국부 통계조사자료를 이용한 자산별 경제적 감가상각추정에 대한 연구)

  • Cho, Jin-Hyung;Oh, Hyun-Seung;Lee, Sae-Jae;Suh, Jung-Yul
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.30 no.4
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    • pp.170-181
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    • 2007
  • The purpose of computing economic depreciation value is to find valuation of assets closely in line with market prices. The valuation of industrial assets are called Engineering Valuation. The two representative techniques for such valuation are Hulten-Wykoff Method, which estimates real value using regression equations, and T-factor Method devised at Iowa State University. The two are all empirical methods for computing service life (duration period). In this paper, we derived the service life by empirical methods using national wealth statistics, and also by more conventional methods such as original group method and retirement method. The results from each method are compared with one another. We also computed economic service life from these results. In S. Korea where amount of asset value statistics is still insufficient, the most effective method for empirically computing economic service life turns out to be the one using national wealth statistics. In addition, we also present economic relationship between depreciation value computed by using Hulten-Wykoff Method and depreciation value computed by using T-factor Method.

A Study on the Stress Concentration Factor and Fatigue Strength for T-Tubular Joints by FEM (유한요소법에 의한 튜블라 이음부의 응력집중계수 및 피로강도 해석)

  • 엄동석;강성원;하우일
    • Journal of Ocean Engineering and Technology
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    • v.8 no.2
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    • pp.141-150
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    • 1994
  • In designing, the strength of tubular joint has been an important problem for integrity of steel structures in which many tubular members are used. This paper presents the results of FEM analysis on stress concentration and fatigue crack initiation life for two types of tubular joints. One is circular and rectangular T type joints which consist of circular brace and rectangular chord. Another is circular and circular T type joints which consist of circular brace and circular chord. FEM analyses were performed under the axial load and in-plane bending moment. The fatigue crack initiation life can be estimated by using $\varepsilon$-N curve and by applying the Palmgren-Miner linear damage rule. According to the results, the stress concentration factor(SCF) of circular and rectangular joints is higher than that of circular and circular joints. The fatigue crack initiation lives of circular-circular joints and circular-rectangular joints were calculated.

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Development of Side Forming Technology for the Tooth Part Using B.T.Pin in Cold Forming Process (B.T.Pin을 이용한 치형부품의 측면 냉간성형공법 개발)

  • Lee, J.S.;Park, S.J.;Kim, B.M.;Kim, D.H.
    • Transactions of Materials Processing
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    • v.26 no.2
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    • pp.95-100
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    • 2017
  • In this study, the method of process design for side forming of a tooth part used for a component of automobile transmission was suggested using FE-simulations. To develop the side forming for the tooth part, in this paper, the shape factors of B.T.Pin was considered as design parameters. The shape factors of B.T.Pin were selected to be the round of pin, reinforced angle and reinforced length. Based on FE simulation results, appropriate shape factor without causing any defects was selected. In addition, to increase the strength of pin, the combination of shape factor having minimum stress after side forming was selected using FE-simulation. In addition, with design of a die set, cold side forming of the tooth part was experimented to estimate effectiveness of the designed B.T.Pin. From experiments, it was found that the tooth part with complete formation of the tooth was obtained without making any forming defects and punch fracture.

The Relationship between Color Preference and Personality Traits & Personal Factor (색채기호도와 성격특성 및 개인적 요인과의 관계 연구)

  • Bek, Sook-Hee;Choi, Jong-Myoung;Kim, In-Sook
    • Korean Journal of Human Ecology
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    • v.3 no.1
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    • pp.71-80
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    • 1994
  • The purpose of this study was to investigate the relationship between color preference and personality traits & personal factor among secondary school girls. Personality traits were measured. with Lee et al's Personality Scale. The questioniare measuring color preference consists of items designed to assess color and clothing color(T-shirt and slacks) preference and color repugnance. These questionaire were administerd to 576 middle and high school girls in Chungbuk Province. As statistical analysis, chi-square, F-test and correlation were used. The result were; 1. The order of prefered colors were white, yellow and green, and the order of repugnated colors were gray, red and red purple. 2. Personality traits was no signifcant related to color perference and repugnance. 3. Color perference was positively related to age, residential area and type of school. Color repugnance was positively related to age, residential area, type of school and educational background of mother. 4. Yellow red, yellow and white T-shirt were prefered in spring and autumn, white and blue T-shirt were prefered in summer, and black, gray and red T-shirt were prefered in winter. White and blue slacks were prefered in spring, summer and autumn seasons, and black, gray and blue slacks were prefered in winter. 5. There was a positive relationship between color perference and T-shirt color, but was no positive relationship between color perference and slacks color.

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T-shirt Color Preferences and Appearance Satisfaction Related to Extroversion. (티셔츠색 선호 외모만족도와 외향성과의 관계 -남녀 고등학생과 대학생을 중심으로-)

  • 유경숙
    • Journal of the Korean Society of Costume
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    • v.27
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    • pp.75-86
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    • 1996
  • The objectives of this study were to classify the T-shirts color preferences and to examine how T-shirts color preferences and appearances satisfaction vary according to sex school and extroversion. Questionnaire was comprised of four sections: 8 Likert type items of T-shirts color preference: 10 Likert type items of appearance satisfaction: 10 Likert type items of extroversion : and 2 demographic variables. Samples were 335 high school and college students in Kwangju Korea. The data were analyxed using factor analysis and three-way ANOVA. The results of the study were the followings 1. Three segments of T-shirts color preferences derived from factor analysis :F.1 'warm' F. 2 'dark' F.3 'commonplace' 2. Women in high extroversion group liked red color better than men and low extroversion group 3. There were not significant differences in blue and orange color preference according to sex school and extroversion. 4. Therer was interaction effect between sex and school on dark blue color preference. Women liked dark blue color better than did men. 5. Men liked green color better than did women. 6. Women and college students liked pink color better than did men and high school students. 7. College students liked yellow color better than high school students. 8. Men and middle level extroversion group liked purple color better than did women and high and low extroversion group. 9. Men and high level extroversion group had more appearance satisaction than women and low extroversion.

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Effect of Internet shopping mall Attributes on Purchase Intention for Apparel on Internet (인터넷 쇼핑몰 점포속성 지각이 의류제품 구매의도에 미치는 영향 및 비구매 요인에 관한 연구)

  • 홍희숙
    • Journal of the Korean Home Economics Association
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    • v.40 no.4
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    • pp.27-44
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    • 2002
  • The purposes of this study were 1) to identify predictors of consumers′ apparel purchase on Internet shopping malls and 2) to determine reasons that respondents didn\`t have purchase intention of apparel on Internet shopping malls. The data were collected via a self-administered questionnaire from 204 male and female students who experienced shopping for apparel on Internet shopping malls, living in Cheju and analyzed by factor analysis, multiple regression analysis, t-test and paired t-test. Two predictors were found regarding purchase of apparel on the "big box" Internet shopping malls which sells various product categories; apparel quality and fun of order process. On the speciality Internet shopping malls which sells only fashion goods, diverse apparel assortment and easy handling and fun of information search were identified as predictors of apparel purchase. Reasons that respondents didn′t have purchase intention of apparel on Internet shopping malls were summarized and labeled as: difficulty of decision making due to virtual shopping environment, insufficiency of diverse apparels, users′ unease handling, risk of incredible apparel quality, unfamiliarity of Internet shopping and risks of unsecurity. Difficulty of decision making due to virtual shopping environment was determined as the most important factor of reasons that respondents didn′t have purchase intention of apparels in website.

Transcriptional Regulation of the Glial Cell-Specific JC Virus by p53

  • Kim, Hee-Sun;Woo, Moom-Sook
    • Archives of Pharmacal Research
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    • v.25 no.2
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    • pp.208-213
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    • 2002
  • The human polyomavirus JC virus is the etiologic agent of progressive multifocal leukoencephalopathy (PML). As the JC virus early promoter directs cell-specific expression of the viral replication factor large T antigen, transcriptional regulation constitutes a major mechanism of glial tropism in PML. It has been demonstrated that SV4O or JC virus large T antigen interacts with p53 protein and regulates many viral and cellular genes. In this study we founts that p53 represses the JC virus early promoter in both glial and nonglial cells To identify the cis-regulatory elements responsible for p53-mediated repression, deletional and site-directed mutational analyses were performed . Deletion of the enhancer region diminished p53-mediated transcriptional repression. However, point mutations of several transcription factor binding sites in the basal promoter region did not produce any significant changes. In support of this observation, when the enhancer was fused to a heterologous promoter, p53 red reduced the promoter activity about three fold. These results indicate that the enhancer region is important for tole repression of JC virus transcription by p53. Furthermore, coexpression of JC virus T antigen with a p53 protein abolished p53-mediated repression of the JC virus early promoter in non-glial cells, but not in glial cells. This finding suggests that T antigen interacts with p53 and regulates JC virus transcription in a cell-specific manner.

Does Acute A-tDCS (Anodal Transcranial Direct Current Stimulation) Improve Golf Performance of Professional Golfers?

  • Kyung YOO;Hwang-Woon MOON
    • Journal of Sport and Applied Science
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    • v.8 no.3
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    • pp.1-6
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    • 2024
  • Purpose: This study aims to verify the effectiveness of acute anodal transcranial direct current stimulation (A-tDCS) using Halo Sport headset device on golf performance in professional golfers. Research design, data, and methodology: Eight professional golfers who voluntary participated in high-level golf tournaments were recruited in this study. They attended one single-session intervention which was stimulated by Halo Sport headset device (n=8). The A-tDCS halo sport session lasted for 20 minutes and stimulated on the motor control area of the cortex (M1). Four golf swing performance tasks (driver, iron, 100-yard shot, 50-yard shot) were performed before and after halo intervention. Key indicators of golf swing performance (Club Speed, Face Angle, Ball Speed, Smash Factor, Spin Rate, Side, Carry, Total) were collected by Trackman launch monitor. Results: In Halo session, there were no found statistical significance in driver, iron and approach (100, 50 yards) after intervention (P<0.05). Even some of variables (face angle, smash factor, carry and total distance) in driver, distance accuracy of 100 yards and direction accuracy of 50 yards were slightly improved tendency, but it was not significant (P<0.05). Meanwhile, there was any enhance all of variables in iron. Conclusions: As a result, the current study concludes that the acute A-tDCS halo sport intervention has no effect on the positive golf performance improvement for professional players. Further implications were discussed.