• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.68-80
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• 2012

Purpose : More recently, combined PET/MR scanners have been developed in which the MR data can be used for both anatometabolic image formation and attenuation correction of the PET data. For quantitative PET information, correction of tissue photon attenuation is mandatory. The attenuation map is obtained from the CT scan in the PET/CT. In the case of PET/MR, the attenuation map can be calculated from the MR image. The purpose of this study was to assess the quantitative differences between MR-based and CT-based attenuation corrected PET images. Materials and Methods : Using the uniform cylinder phantom of distilled water which has 199.8 MBq of $^{18}F$-FDG put into the phantom, we studied the effect of MR-based and CT-based attenuation corrected PET images, of the PET-CT using time of flight (TOF) and non-TOF iterative reconstruction. The images were acquired from 60 minutes at 15-minute intervals. Region of interests were drawn over 70% from the center of the image, and the Scanners' analysis software tools calculated both maximum and mean SUV. These data were analyzed by one way-anova test and Bland-Altman analysis. MR images are segmented into three classes(not including bone), and each class is assigned to each region based on the expected average attenuation of each region. For clinical diagnostic purpose, PET/MR and PET/CT images were acquired in 23 patients (Ingenuity TF PET/MR, Gemini TF64). PET/CT scans were performed approximately 33.8 minutes after the beginnig of the PET/MR scans. Region of interests were drawn over 9 regions of interest(lung, liver, spleen, bone), and the Scanners' analysis software tools calculated both maximum and mean SUV. The SUVs from 9 regions of interest in MR-based PET images and in CT-based PET images were compared. These data were analyzed by paired t test and Bland-Altman analysis. Results : In phantom study, MR-based attenuation corrected PET images generally showed slightly lower -0.36~-0.15 SUVs than CT-based attenuation corrected PET images (p<0.05). In clinical study, MR-based attenuation corrected PET images generally showed slightly lower SUVs than CT-based attenuation corrected PET images (excepting left middle lung and transverse Lumbar) (p<0.05). And percent differences were -8.01.79% lower for the PET/MR images than for the PET/CT images. (excepting lung) Based on the Bland-Altman method, the agreement between the two methods was considered good. Conclusion : PET/MR confirms generally lower SUVs than PET/CT. But, there were no difference in the clinical interpretations made by the quantitative comparisons with both type of attenuation map.

• The Korean Journal of Nuclear Medicine Technology
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• v.12 no.1
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• pp.27-32
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• 2008

Purpose: The evaluation of SUV (Standardized Uptake Values) for quantitative analysis in PET exam is the most significant. In PET exam, we make attenuation correction images by using $^{68}Ge$, $^{137}Cs$ or CT data. At this time, a distorted attenuation map affects quantitative analysis. After the exam using barium-sulfate and high density of barium contrast make attenuation map distorted. And then it brings bed influences on SUV. The aim of this study is to verify the relationship between high density barium-sulfate and SUV in PET exam. Materials and Methods By using $^{18}F$-FDG, we made barium-sulfate powder, density of 0, 1.5, 3, 5, 10 and 15% respectively and acquired PET and PET/CT images per each density. And we examined SUV variations from PET and PET/CT images according to differences of barium's density. Moreover, we finally calculated SUV causing variations in HU (Hounsfield Units) values to justify whether the differences of barium density bring any changes in PET/CT exam. Results: From PET images acquired from transmission scan with $^{68}Ge$, we got SUV figures from 6.46 to 6.8 in barium density between 0 to 15 percent. On the other hand, In PET images acquired from Tx scan that using CT, SUV was 6.77 to 23.73, derived from the same barium density. And CT HU values range from 29 to 2004. Conclusion: PET images from Tx data using $^{68}Ge$ weren't affected by barium density and had no differences in SUV. But in the PET/CT images using CT Tx data, there's considerable variations in HU and SUV values according to a difference of barium density in HU values. To perform a precise examination, barium sulfate should be removed from a human body before performing a PET exam.

• Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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• 2006.05a
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• pp.146-151
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• 2006

현재 국가지리정보유통망을 통해 유통되고 있는 수치지도(Digital map)는 대부분 항공 측량사진(Air survey Photographs)이나 위성영상(Satellite images)을 통해 취득된 토지 피복의 형상을 기반으로 제작된 지도들이다. 정사사진으로부터 취득된 지형정보를 기호화, 단순화한 수치지도는 실제 사물의 형태와 많은 차이가 있어 지형과 시설물의 변이를 사실대로 반영하지 못한다. 특히 최근 들어 지하시설물이나 건축기술의 발달로 층별 구조가 다양해진 건축물의 형태 등은 정사사진으로는 식별이 불가능하고 건물의 경우 지붕의 형태로 묘사되는 등 표현에 한계가 있다. 도심지역을 대상으로 제작된 1/1,000수치지형도나 일부 지자체나 공공기관 등에서 제작된 $1/500{\sim}1/2,500$ 수치지형도는 상세한 지형정보를 포함하고 있는 높은 정밀도의 수치지도이지만, 도시지역의 변이가 빠르게 일어나고 있기 때문에 자료 신뢰성과 최신성을 유지하는데 한계가 있다. 따라서 본 연구는 현지조사나 측량에 의존하고 있는 정사사진으로부터 취득이 불가능한 지형자료의 취득이나 수년단위인 갱신주기의 한계를 극복하고 실시간으로 수치지도를 수정갱신 할 수 있는 대안으로 일반측량성과도의 활용방안을 제시하고자 한다. 일반측량업에서 생산되는 일반측량성과도는 임시 도근점에 의해 측량을 실시하고 지적경계점과 현황기지점을 도해법에 의해 지적도와 중첩시켜 제작한 측량도로서, 일반측량 성과도에 절대좌표체계를 부여하고 수치지도와 매칭 기법을 제시함으로서 경제적이고 신속한 실시간 수치지도 수정갱신체계를 확립할 수 있고, 자료의 공유함으로써 중복측량을 방지할 수 있다.보 등)를 활용, 구축된다. 교통분석용 네트워크는 구축시점에 따라 현재 및 장래 네트워크로 구분되며 장래 네트워크는 기준년도부터 2031년까지 5년 단위로 계획된 장래도로를 반영하여 구축된다. 교통주제도 및 교통분석용 네트워크는 국가교통DB구축사업을 통해 구축된 자료로서 교통체계효율화법 제9조의4에 따라 공공기관이 교통정책 및 계획수립 등에 활용할 수 있도록 제공하고 있다. 건설교통부의 승인절차를 거쳐 제공하며 활용 후에는 갱신자료 및 활용결과를 통보하는 과정을 거치도록 되어있다. 교통주제도는 국가의 교통정책결정과 관련분야의 기초자료로서 다양하게 활용되고 있으며, 특히 ITS 노드/링크 기본지도로 활용되는 등 교통 분야의 중요한 지리정보로서 구축되고 있다..20{\pm}0.37L$, 72시간에 $1.33{\pm}0.33L$로 유의한 차이를 보였으므로(F=6.153, P=0.004), 술 후 폐환기능 회복에 효과가 있다. 4) 실험군과 대조군의 수술 후 노력성 폐활량은 수술 후 72시간에서 실험군이 $1.90{\pm}0.61L$, 대조군이 $1.51{\pm}0.38L$로 유의한 차이를 보였다(t=2.620, P=0.013). 5) 실험군과 대조군의 수술 후 일초 노력성 호기량은 수술 후 24시간에서 $1.33{\pm}0.56L,\;1.00{\ge}0.28L$로 유의한 차이를 보였고(t=2.530, P=0.017), 술 후 72시간에서 $1.72{\pm}0.65L,\;1.33{\pm}0.3L$로 유의한 차이를 보였다(t=2.540, P=0.016). 6) 대상자의

• Korean Journal of Remote Sensing
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• v.33 no.5_1
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• pp.469-480
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• 2017

This study aims to understand the relationship between lineaments and epicenters in Geochang region, Gyungsangnam-do, South Korea. An instrumental observation of earthquakes has been started by Korea Meteorological Administration (KMA) since 1978 and there were 6 earthquakes with magnitude ranging 2 to 2.5 in Geochang region from 1978 to 2016. Lineaments were extracted from LANDSAT 8 satellite image and shaded relief map displayed in 3-dimension using Digital Elevation Model (DEM). Then, lineament density was statistically examined by hotspot analysis. Hexagonal grids were generated to perform the analysis because hexagonal pattern expresses lineaments with less discontinuity than square girds, and the size of the grid was selected to minimize a variance of lineament density. Since hotspot analysis measures the extent of clustering with Z score, Z scores computed with lineaments' frequency ($L_f$), length ($L_d$), and intersection ($L_t$) were used to find lineament clusters in the density map. Furthermore, the Z scores were extracted from the epicenters and examined to see the relevance of each density elements to epicenters. As a result, 15 among 18 densities,recorded as 3 elements in 6 epicenters, were higher than 1.65 which is 95% of the standard normal distribution. This indicates that epicenters coincide with high density area. Especially, $L_f$ and $L_t$ had a significant relationship with epicenter, being located in upper 95% of the standard normal distribution, except for one epicenter in $L_t$. This study can be used to identify potential seismic zones by improving the accuracy of expressing lineaments' spatial distribution and analyzing relationship between lineament density and epicenter. However, additional studies in wider study area with more epicenters are recommended to promote the results.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.44 no.2
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• pp.166-170
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• 1999

The identification of quantitative trait loci (QTL) has the potential to enhance the efficiency of im- proving food processing traits of soybean. In this study, 92 restriction fragment length polymorphism (RFLP) loci and two morphological markers (W$_1$ and T) were used to identify QTL associated with food processing traits of soybean for sprout in 83 F$_2$-derived lines from a cross of ＇Pureun＇ x ＇Jinpum 2＇. The genetic map consisted of 76 loci which covered about 760 cM and converged into 20 linkage groups. Eighteen markers remained unlinked. Phenotypic data were collected for hypocotyl length, abnormal seedling rate, and sprout yield seven days after seed germination at 2$0^{\circ}C$. Based on the single-factor analysis of variance, eight independent markers were associated with hypocotyl length. Four of seven markers associated with abnormal seedling rate were identified as independent. Seven loci were associated with sprout yield. For three different traits, much of genetic variation was explained by the identified QTL in this population. Several RFLP markers in linkage group (LG) Bl were detected as being associated with three traits, providing a genetic explanation for the biological correlation of sprout yield with hypocotyl length (r=OA07＊＊＊) and with abnormal seedling rate (r=-406＊＊＊).

• Korean Journal of Mathematics
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• v.27 no.3
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• pp.661-690
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• 2019

The soft compactness notion via soft topological spaces was first studied in [10,29]. In this work, soft semi-open sets are utilized to initiate seven new kinds of generalized soft semi-compactness, namely soft semi-$Lindel{\ddot{o}}fness$, almost (approximately, mildly) soft semi-compactness and almost (approximately, mildly) soft semi-$Lindel{\ddot{o}}fness$. The relationships among them are shown with the help of illustrative examples and the equivalent conditions of each one of them are investigated. Also, the behavior of these spaces under soft semi-irresolute maps are investigated. Furthermore, the enough conditions for the equivalence among the four sorts of soft semi-compact spaces and for the equivalence among the four sorts of soft semi-$Lindel{\ddot{o}}f$ spaces are explored. The relationships between enriched soft topological spaces and the initiated spaces are discussed in different cases. Finally, some properties which connect some of these spaces with some soft topological notions such as soft semi-connectedness, soft semi $T_2$-spaces and soft subspaces are obtained.

• Journal of Animal Science and Technology
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• v.46 no.4
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• pp.525-536
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• 2004

The objective of this study was to identify the quantitative traits loci(QTL) for meat quality traits in pigs. Three-generation resource population was constructed from a cross between Korean native boars and Landrace sows. The resource population including founders, $F_1$ and $F_2$ was genotyped for 23 microsatellite markers on chromosome 7. The sex average total length of linkage map on chromosome 7 was estimated 154.6 cM. Meat quality traits including meat pH, meat color, drip loss, shear force, heating loss, crude fat, crude protein, crude ash and water content in muscle were collected from $F_2$ animals. For the QTL mapping, we used $F_2$ QTL Analysis Servlet of QTL express for web-based QTL mapping tools(http://qtl.cap.ed.ac.uk/). The QTLs for CIE-a and CIE-b on SSC7 were significantly detected at 1% and 5% chromosome-wide level, respectively.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.12
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• pp.1644-1650
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• 2011

This study was conducted to detect quantitative trait loci (QTL) affecting meat quality in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 17 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between models were used to characterize the QTL for mode of gene expressions. A total of 10 (32) QTL were detected at the 5% genome (chromosome)-wise level for the analyzed traits. Of the 42 QTL detected, 13 QTL were classified as Mendelian, 10 as paternal, 14 as maternal, and 5 as partial expressed QTL, respectively. Among the QTL detected at 5% genome-wise level, four QTL had Mendelian mode of inheritance on SSCs 5, 10, 12, and 13 for cooking loss, drip loss, crude lipid and crude protein, respectively; two QTL maternal inheritance for pH at 24-h and shear force on SSC11; three QTL paternal inheritance for CIE b and Hunter b on SSC9 and for cooking loss on SSC15; and one QTL partial expression for crude ash on SSC13, respectively. Most of the Mendelian QTL (9 of 13) had a dominant mode of gene action, suggesting potential utilization of heterosis for genetic improvement of meat quality within the cross population via marker-assisted selection.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.07a
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• pp.295-296
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• 2016

본 연구에서는 LED 광 자극이 뇌의 어느 영역을 자극하여 신경신호를 전달하는지에 관해서 관찰하고자 연구를 진행하였다. 광 자극에 의한 뇌 영역의 활성변화를 관찰하기 위하여 실험용 소동물과 영상장비인 9.4T MRI를 이용하여 연구를 수행 하였다. 실험용 소동물은 Balb/c 마우스를 이용하였으며 기능적 자기공명영상 획득 방법 중 하나인 에코평면영상 기법을 이용하여 뇌 영상을 획득 하였다. 획득한 영상을 바탕으로 뇌 영역의 자극 정도를 확인해보기 위해 영상처리기법인 재편성(realignment), 일치(co-registration), 표준화(normalization), 평활화(smoothing) 방법으로 영상을 전처리 하고, statistical parametric map (SPM12)을 사용하여 분석하였다. 본 연구에서는 광자극이 소동물 뇌 영역 중 하나인 상구(Superior colliculus)영역과 대뇌의 시각피질 (visual cortex, V1) 영역에서 자극을 일으키는 것을 확인할 수 있었다.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.669-676
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• 2007

This study was conducted to detect quantitative trait loci (QTL) affecting growth and body composition in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 18 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between the models were used to characterize QTL for mode of expressions. A total of 8 (39) QTL were detected at the 5% genome (chromosome)-wise level for the 17 analyzed traits. Of the 47 QTL detected, 21 QTL were classified as Mendelian expressed, 13 QTL as paternally expressed, 6 QTL as maternally expressed, and 7 QTL as partially expressed. Of the detected QTL at 5% genome-wise level, two QTL had Mendelian mode of inheritance on SSC6 and SSC9 for backfat thickness and bone weight, respectively, two QTL were maternally expressed for leather weight and front leg weight on SSC6 and SSC12, respectively, one QTL was paternally expressed for birth weight on SSC4, and three QTL were partially expressed for hot carcass weight and rear leg weight on SSC6, and bone weight on SSC13. Many of the Mendelian QTL had a dominant (complete or overdominant) mode of gene action, and only a few of the QTL were primarily additive, which reflects that heterosis for growth is appreciable in a cross between Korean native pig and Landrace. Our results indicate that alternate breed alleles of growth and body composition QTL are segregating between the two breeds, which could be utilized for genetic improvement of growth via marker-assisted selection.