• Journal of Ocean Engineering and Technology
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• v.25 no.3
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• pp.73-84
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• 2011

This is the fifth in a series of companion papers dealing with the dynamic hardening properties of various marine structural steels at intermediate strain rates. Five steps of strain rate levels (0.001, 1, 10, 100, 200/s) and three steps of temperature levels (LT ($-40^{\circ}C$), RT, and HT ($200^{\circ}C$)) were taken into account for the dynamic tensile tests of three types of marine structural steels: API 2W50 and Classifications EH36 and DH36. The total number of specimens was 180 pieces. It was seen that the effects of dynamic hardening became clearer at LT than at RT. Dynamic strain aging accompanying serrated flow stress curves was also observed from high temperature tests for all kinds of steels. The dynamic hardening factors (DHFs) at the two temperature levels of LT and RT were derived at the three plastic strain levels of 0.05, 0.10, 0.15 from dynamic tensile tests. Meanwhile, no DHFs were found for the high temperature tests because a slight negative strain rate dependency due to dynamic strain aging had occurred. A new formulation to determine material constant D in a Cowper-Symonds constitutive equation is provided as a function of the plastic strain rate, as well as the plastic strain level. The proposed formula is verified by comparing with test flow stress curves, not only at intermediate strain rate ranges but also at high strain rate ranges.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.2
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• pp.103-118
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• 2012

In this study, the cellular protective effect of isoquercitrin against $H_2O_2$ and rose bengal-indued HaCaT cell damage was investigated. The ethosome and elastic liposome for enhanced transdermal delivery were prepared. Particle size, loading efficiency and cumulative permeated amounts of them were evaluated. Isoquercitrin didn't show any characteristic cytotoxicity at 50 ${\mu}M$. When HaCaT cells were treated with 5 mM $H_2O_2$ and 25 ${\mu}M$ rose bengal, isoquercitrin protected the cells against the oxidative damage in a concentration dependent manner (6.25 ~ 50 ${\mu}M$). The size of 0.03 % isoquercitrin loaded ethosome was 222.85 nm and the loading efficiency was 82.26 %. The ethosome loaded with 0.03 % isoquercitrin was stable and maintained the constant particle size for 2 weeks after being prepared. The ethosome exhibited more enhanced skin permeability than general liposome and ethanol solution. The optimal ratio of lipid to surfactant of 0.1 % isoquercitrin loaded elastic liposomes was observed to be 89 : 5 through evaluating particle size (341.2 nm), deformability index (59.89), loading efficiency (54.3 %), and skin permeability (54.4 %).

• Toxicological Research
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• v.29 no.2
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• pp.87-90
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• 2013

The potential role of topical valproate (VPA) in hair regrowth has been recently suggested. However, safety reports of VPA as a topical formulation are lacking. Therefore, in the present study, we investigated whether VPA causes skin irritation in humans. We first performed a cell viability test and showed that VPA did not exhibit toxicity toward HaCaT keratinocytes, fibroblasts, and RBL-3H mast cells. We then performed clinical patch test and skin irritation test through transdermal drug delivery with the help of microneedle rollers. No significant findings were obtained in the clinical patch test. In the skin irritation test, only 1 patient showed erythema at 1 hr, but the irritation reaction faded away within a few hours. Erythema and edema were not observed at 24 hr. We concluded that VPA has minimal potential to elicit skin irritation. Therefore, we consider that VPA can safely be applied to human skin.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.1467-1475
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• 2007

This paper investigates the modal acoustic power by a cascade of flat-plate airfoils interacting with homogeneous, isotropic turbulence. Basic formulation for the acoustic power upstream and downstream is based on the analytical theory of Smith and its generalization due to Cheong et al. The acoustic power spectrum has been expressed as the sum of cut-on acoustic modes, whose modal power is the product of three terms: a turbulence series, an upstream or downstream power factor and an upstream or downstream acoustic response function. The effect of these terms in the modal acoustic power has been examined. For isotropic turbulence gust, the turbulent series are only reducing factor of the modal acoustic power. The power factor tends to reduce the modal acoustic power in the upstream direction, although the power factor is liable to increase the modal acoustic power in the downstream direction. The modes close to cut-off are decreasing strongly, especially in the downstream direction. Therefore the modes close to cut-off don't contribute highly to the radiated acoustic power in the downstream direction, although the modal acoustic pressure is high for these modes.

• The Korean Journal of Applied Statistics
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• v.24 no.1
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• pp.61-69
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• 2011

In GARCH context, the conditional variance (or volatility) is of a quadratic function of the observation process. Examine standard ARCH/GARCH and their variant models in terms of quadratic formulations and it is interesting to note that most models in GARCH context have contained neither the first order term nor the interaction term. In this paper, we consider three models possessing the first order and/or interaction terms in the formulation of conditional variances, viz., quadratic GARCH, absolute value GARCH and bilinear GARCH processes. These models are investigated with a view to model comparisons and applications to financial time series in Korea

• The Korean Journal of Pesticide Science
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• v.10 no.2
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• pp.84-90
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• 2006

In the field of agriculture, FT-NIR mainly has been used in qualitative management of produces without sample preparation with a data set built from a quantitative value of sample components confirmed by another analytical instrument. On the other hand, inert materials of crop protection products nearly haven't examined instrumental analysis because of analytical problems of high-molecular inert materials and a variety of formulation type. This study, results make it possible to solve an analytical problems of crop protection products using FT-NIR chemometrics technique from spectrum calculator module.

• Structural Engineering and Mechanics
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• v.1 no.1
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• pp.87-102
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• 1993

A $C^{\circ}$ continuous finite element formulation of a higher order displacement theory is presented for predicting linear and geometrically non-linear in the sense of von Karman transient responses of composite and sandwich plates. The displacement model accounts for non-linear cubic variation of tangential displacement components through the thickness of the laminate and the theory requires no shear correction coefficients. In the time domain, the explicit central difference integrator is used in conjunction with the special mass matrix diagonalization scheme which conserves the total mass of the element and included effects due to rotary inertia terms. The parametric effects of the time step, finite element mesh, lamination scheme and orthotropy on the linear and geometrically non-linear responses are investigated. Numerical results for central transverse deflection, stresses and stress resultants are presented for square/rectangular composite and sandwich plates under various boundary conditions and loadings and these are compared with the results from other sources. Some new results are also tabulated for future reference.

• Journal of muscle and joint health
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• v.27 no.2
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• pp.103-111
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• 2020

Purpose: This study aimed to investigate the relationship between general hospital nurses' work environment, resilience, and intention to remain, as well as to identify the factors associated with nurses' intention to remain. Methods: Study participants were nurses at a general hospital in Jeollabuk-do, South Korea. Data collection was undertaken from July 6th to 20th, 2017, through questionnaire responses from 257 nurses. Descriptive statistics were employed for data analysis, including: independent t-test, one way ANOVA, Pearson's correlation coefficient, and multiple regression analysis using SPSS/WIN 22.0. Results: Nurses' work environment, resilience, and intention to remain were found to have a statistically significant correlation. Intention to remain showed statistically significant positive correlations with the nurse's work environment (r=.72, p<.001), resilience (r=.50, p<.001). Factors found to influence intention to remain were work environment, resilience, job satisfaction, and health status. Conclusion: The study findings support the development of a specialized program to strengthen nurses' intention to remain. During the program's formulation, it is necessary to improve nurses' work environment and find ways to bolster the resilience of individual nurses.

• Natural Product Sciences
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• v.10 no.1
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• pp.16-19
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• 2004

Triphala churna is a widely used herbal formulation that contains equal proportion of dried fruit powder of Emblica officinalis, Terminalia chebula and Terminalia belirica. In the Indian system of medicine, it is used in cleaning wounds, urinary disorders, diabetes mellitus, leprosy, constipation, eyesight promotion, piles, and as a rejuvenator. In the present study, the methanolic extract of 5 commercial Triphala was evaluated for antioxidant activity by 1,1-diphenyl-2-picryl-hydrazyl free radical scavenging method, total phenolic content by Folin-Ciocalteu method and gallic acid equivalents (GAE) by high performance thin layer chromatographic (HPTLC) method. All extracts exhibited antioxidant activity significantly. The $IC_{50}$ of the extracts ranged between $7.16\;to\;12.96\;{\mu}g/ml$. The total phenolic content of the extracts was found to be 195.3-296.4 mg of GAE/gm of GAE/gm dw. The HPTLC chromatographic data reveal that the content of GAE present in the extract was found to be $7.17-4.11\;{\mu}g/ml$. The study reveals that out of the churnas analysed, C was found to exhibit the most potent antioxidant activity. A clear correlation between $IC_{50}$ and content of GAE nor the total phenolic content could be observed. The study reveals that the consumption of Triphala would exert several beneficial effects by virtue of its antioxidant activity.

• Journal of computational fluids engineering
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• v.19 no.1
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• pp.27-33
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• 2014

A new and efficient implicit scheme is proposed to obtain a steady-state solution in time integration and the comparison of characteristics with the approximation ways for the implicit method to solve the incompressible Navier-Stokes equations is provided. The conservative, finite-volume cell-vertex upwind scheme and artificial compressibility method using dual time stepping for time accuracy is applied in this paper. The numerical results obtained indicate that the direct application of Jacobian matrix to the Lower and upper sweeps of implicit LU-SGS leads to better performance as well as convergence regardless of CFL number and true time step than explicit scheme and approximation of Jacobian matrix. The flow simulation around box in uniform flow with unstructured meshes is demonstrated to check the validity of the current formulation.