• Agricultural and Biosystems Engineering
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• 제7권1호
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• pp.42-47
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• 2006

The objective of this study was to investigate the effects of air-phase germination with water-spraying and anion stimuli on germination ratio, sprout growth and ${\gamma}$-aminobutyric acid (GABA) of brown rice. Air-phase germination method with intermittent spraying water improved germination ratio and sprout growth by about 100% compared with the conventional water-soaking method. Anion radiation was applied during the germination process and improved the germination ratio, sprout growth and color quality of the germinated brown rice. Germination ratio and sprout growth were improved up to 9% with anion radiation, and its brightness was higher than brown rice germinated with no anion radiation. The air-phase germination with water-spraying improved the GABA content of germinated brown rice by about 8-9 times compared with that of brown rice.

• Biomolecules & Therapeutics
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• 제13권1호
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• pp.32-34
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• 2005

Effect of isoliquiritigenin isolated from the heartwood of Dalbergia odorifera T. Chen (Leguminosae) on mushroom tyrosinase activity was investigated in vitro using L-tyrosine and L-3, 4-dihydroxyphenylalanine (L-DOPA) as the substrates. When L-tyrosine was used as a substrate, both isoliquiritigenin and kojic acid, a positive control, inhibited tyrosinase activity in a concentration-dependent manner. IC$_{50}$ values of isoliquiritigenin and kojic acid were 61.4 and 52.2 ${\muM}$, respectively. However, isoliquiritigenin showed week inhibitory effect on the oxidation of L-DOPA by tyrosinase with inhibition ratio of 9.1 ${\pm}$ 7.1% at 100 ${\muM}$. It is also suggested that 3-unsubstituted and 4-hydroxyl phenyl group in isoliquiritigenin plays an important role on the inhibition of tyrosinase activity when L-tyrosine was used as a substrate. Analysis of Lineweaver-Burk plot showed that isoliquiritigenin acts as a competitive inhibitor in case of L-tyrosine as a substrate.

• Nutrition Research and Practice
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• 제11권3호
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• pp.198-205
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• 2017

BACKGROUND/OBJECTIVES: The anti-diabetic activity of pear through inhibition of ${\alpha}-glucosidase$ has been demonstrated. However, little has been reported about the effect of pear on insulin signaling pathway in obesity. The aims of this study are to establish pear pomace 50% ethanol extract (PPE)-induced improvement of insulin sensitivity and characterize its action mechanism in 3T3-L1 cells and high-fat diet (HFD)-fed C57BL/6 mice. MATERIALS/METHODS: Lipid accumulation, monocyte chemoattractant protein-1 (MCP-1) secretion and glucose uptake were measure in 3T3-L1 cells. Mice were fed HFD (60% kcal from fat) and orally ingested PPE once daily for 8 weeks and body weight, homeostasis model assessment of insulin resistance (HOMA-IR), and serum lipids were measured. The expression of proteins involved in insulin signaling pathway was evaluated by western blot assay in 3T3-L1 cells and adipose tissue of mice. RESULTS: In 3T3-L1 cells, without affecting cell viability and lipid accumulation, PPE inhibited MCP-1 secretion, improved glucose uptake, and increased protein expression of phosphorylated insulin receptor substrate 1 [p-IRS-1, ($Tyr^{632})$)], p-Akt, and glucose transporter type 4 (GLUT4). Additionally, in HFD-fed mice, PPE reduced body weight, HOMA-IR, and serum lipids including triglyceride and LDL-cholesterol. Furthermore, in adipose tissue, PPE up-regulated GLUT4 expression and expression ratio of p-IRS-1 ($Tyr^{632})/IRS$, whereas, down-regulated p-IRS-1 ($Ser^{307})/IRS$. CONCLUSIONS: Our results collectively show that PPE improves glucose uptake in 3T3-L1 cells and insulin sensitivity in mice fed a HFD through stimulation of the insulin signaling pathway. Furthermore, PPE-induced improvement of insulin sensitivity was not accompanied with lipid accumulation.

• Journal of Chest Surgery
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• 제28권8호
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• pp.766-771
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• 1995

The trachea is defined as the airway from the inferior border of the cricoid cartilage to the top of the carinal spur. This paper would confirm the normal tracheal length of Korean adults through the actual measurement using the fiberoptic bronchoscopy. The subjects of this study were 25 patients, 13 males and 12 females between the age of 20 to 69 without abnormality on the neck, trachea, mediastinum and lung pharenchyme on the preoperative chest X-ray, who received the operations from the period of July to September, 1994. For those patients who had heart diseases, the cardiothoracic ratio was below 50%. The measurement was performed on the patients with endotracheal intubation under the general anesthesia in supine and neutral position. The tracheal length was calculated by the difference between the length from the tip of the endotracheal tube [E-tube to carina and to the needle which was inserted into the E-tube at the lower border of the palpated cricoid cartilage, by inserting the broncoscopy through the E-tube. The result was as follow : 1 The measured tracheal length for men was 11.8 0.2 cm[mean standard deviation and women was 10.5 0.3 cm, and that was longer than this [p<0.01 . The average was 11.2 1.0 cm and the standard error was 0.20 cm. 2 According to the correlation between the tracheal length to weight, height[Ht , age, and body surface area[BSA respectively, the Ht [p=0.003 , age [p=0.055 , and the BSA[p=0.017 were significant, while weight was not [p=0.314 . 3 From the regression analysis of the tracheal length[T.L. to the Ht, Age, and the BSA which were significant, the following equation was derived.i Ht : T.L.= -1.29 + 0.076 x Ht [P=0.003 ii Age: T.L.= 10.04 + 0.028 x Age [P=0.055 iii BSA : T.L.= 5.60 + 3.48 x BSA [P=0.017 iv In multi-regression : T.L. = -4.15 + 0.034 x Age + 0.085 x Ht [P=0.0002]

• Journal of Ginseng Research
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• 제6권1호
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• pp.38-45
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• 1982

To determine the optimum light intensity for growth of ginseng plants, change of temperature, moisture content in son, occurrence alternaria blight, defoliation rate, chlorophyll contents, and growth of shoots and roots were investigated under different light intensity such as 5%, 10%, 20% and 30% light transmittance rare(L.T.R.). The results obtained were as follows. 1. Maximum temperature under the shading was increased as the increase of light intensity, whereas soil moisture content decreased 2. As the increase of light intensity, stem and Peduncle length, leaf area, and chlorophyll contents decreased significantly but length and width of the leaf was not significant, while stem diameter, special leaf weight and chlorophyll a/chl. b ratio increased 3. Stem color was shown dark purp!e as the increase of light intensity. 4. Photosynthesis during the day was highest at 9 A.M. and decreased as time passed in all plots. The means of photouynthesis during the day showed in the order of 20%, 10%, 30%, 5% L.T.R., and optimum light intensity for highest photosxthesis was 18.4% L.T.R. by theoritical equation. 5. It was showed a tendency that alternaria leaf blight of ginseng plants was increased as the increase of light intensity. 6. Defoliation rate of ginseng plants was increased as the increase of light intensity, especially all plants were defoliated by late June without shading. 7. Yield percentage of the rear line was increased as the increase of light intensity. Root weight per plant showed in the order of 20%, 10%, 30%, 5% L.T.R., and optimum light intensity for the best yield was 18.5% L.T.R. by theeritical equation.

• Parasites, Hosts and Diseases
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• 제31권3호
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• pp.231-238
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• 1993

폐흡충 피낭유충을 BALB/c 마우스에 경구 감염시킨 후 마우스를 시기별(3일, 1주, 2주, 3주, 4주, 5주, 7주, 9주, 13주 및 23주)로 희생시켜 말초혈액내 호산구수와 혈청내 IgE 항체가를 측정하는 한편 비장 림프구를 분리하여 림프구 아군(helper T, cytotoxic / suppressor T, pan T)에 대한 단세포군 항체를 결합시켜 EPICS C fluorocytometer로 분석하였다. 폐흡충에 대한 혈청내 총 IgE 항체가는 감염 3주부터 증가되어 감염 4주에 높게 증가되었으며 13주 이후 23주까지 높은 항체가가 유지되었다. 말초혈액내 호산구수는 감염 2주 부터 증가되어 감염 9주에 $664.1/\textrm{mm}^3$으로 가장 증가 되었으며 그 이후에는 감소하여 23주에는 정상보다 약간 증가되었다. 폐흡충을 감염시키고 감염 3일, 1주, 2주, 3주, 4주, 7주 및 23주에 T 림프구 아군을 분석한 결과 L3T4 helper T 림프구와 Lyt-2 cytotoxic / suppressor T 림프구의 비율은 감염 군에서 감염 초기에 대조군에 비해 약간 감소된 경향을 보였으나 대조군과 유의한 차이를 보이지 않았다. Thy 1.2 pan T 림프구의 비율은 감염 2주와 4주에 대조군에 비해 유의하게 감소되었고(P<0.05) 7주 이후에는 대조군과 비슷하였다. 이러한 결과들로 보아 마우스의 폐흡충감염에서 특이 항원이나 마이토젠의 자극이 없이는 비장킬프구의 아군분포에 큰 변화가 없는 것으로 생각된다. 생각된다.

• Computers and Concrete
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• 제14권1호
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• pp.1-18
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• 2014

The addition of steel fibers in concrete mixture is recognized as a non-conventional mass reinforcement scheme that improves the torsional, flexural, and shear behavior of structural members. However, the analysis of fiber reinforced concrete beams under combined torsion, bending, and shear is limited because of the complicated nature of the problem. Therefore, nonlinear 3D finite element analysis was conducted using the "ANSYS CivilFEM" program to investigate the behavior of fiber reinforced concrete L-beams. These beams were tested at different reinforcement schemes and loading conditions. The reinforcement case parameters were set as follows: reinforced with longitudinal reinforcement only and reinforced with steel bars and stirrups. All beams were tested under two different combined loading conditions, namely, torsion-to-shear ratio (T/V) = 545 mm (high eccentricity) and T/V = 145 mm (low eccentricity). Eight intermediate L-beams were constructed and tested in a laboratory under combined torsion, bending, and shear to validate the finite element model. Comparisons with the experimental data reveal that the program can accurately predict the behavior of L-beams under different reinforcement cases and combined loading ratios. The ANSYS model accurately predicted the loads and deformations for various types of reinforcements in L-beams and captured the concrete strains of these beams.

• 한국산림과학회지
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• 제103권4호
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• pp.556-563
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• 2014

본 연구는 시설양묘과정에서 편백 용기묘(2-0묘) 생산을 위해 요구되는 적정 용기의 구 용적 및 생육밀도를 구명하고자 수행하였다. 용기 20구(400 mL/구, 150본/$m^2$), 24구(320 mL/구, 200본/$m^2$), 35구(240 mL/구, 260본/$m^2$)에서 편백의 근원경, 간장, 생체량, 뿌리밀도 및 묘목품질지수를 조사 분석하였다. 용기에 따른 근원경, 간장, 생체량, 뿌리밀도 및 묘목품질지수는 20구 용기에서 유의적으로 가장 높은 값을 보였지만, H/D율과 T/R률은 용기에 따른 차이가 없었다. 단위 면적 당 총 물질생산량은 35구에서 가장 낮았으며, 20구와 24구 용기에서는 유의적 차이가 없었다. 또한, H/D율과 T/R률을 제외한 근원경, 간장, 물질생산량, 뿌리밀도 및 묘목품질지수는 용기 구 용적과는 정의상관관계, 생육밀도와는 부의 상관관계를 보였다. 본 결과를 바탕으로 시설양묘 단계에서 편백 2-0묘는 20구(400 mL/구, 150본/$m^2$) 용기가 적정 규격으로 판단된다. 편백 2-0묘 생산을 위한 적정 용기의 선정으로 우량 묘목 생산 및 경제적 비용 절감 효과와 함께 우수한 조림 성과를 거둘 수 있을 것으로 기대된다.

• 한국환경과학회지
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• 제27권1호
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• pp.39-45
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• 2018

In this study, the International Maritime Organization (IMO)'s guideline MEPC. 277 (64) was developed and evaluated for the removal efficiency of T-N in a SBR and MBR combined process. This combined process of resized equipment based on large capacity water treatment device for a protection of marine aquatic life. In this experiment, T-N concentration of influent and effluent was measured through with the artificial wastewater. The SBR reactor operation time was varied according to the C : N : P ratios so that different conditions for mixing and aeration period in mins (90 : 60, 80 : 40, 70 : 50) and two C: N: P ratios (10 : 5 : 3, 10 : 3 : 1) were used. During experiment in the reactor's aeration and anoxic tank DO concentrations were 3 mg/L and 0.2 mg/L respectively. Furthermore, in the reactor MLSS concentration was 2000 mg/L and flowrate was 2 L/hr. Experiment results showed that C : N : P, 10 : 3 : 1 ratio with 90 mins mixing and 60 mins aeration maximized removal efficiency at 97.3% T-N as compared to other conditions. The application of the SBR and MBR combined process showed efficient results.

• 한국지반환경공학회 논문집
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• 제1권1호
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• pp.79-85
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• 2000

이 연구는 지방의 중소도시에 위치한 소규모 단순매립지내의 매립폐기물과 침출수에 대한 분석을 통하여 안정성을 평가함으로써 매립부지를 주거지역, 상업지역, 기타 다른 목적으로 사용하기 위함이다. 단순투기형으로 매립된 매립층의 깊이는 5.5~8m 정도이었고, 복토 두께는 20~50cm 정도이었다. 매립지의 침출수의 pH는 7.2~7.6이었고, SS, COD, T-N 및 T-P값은 각각 평균 47726, 6193.8, 595.97, 123.9mg/L로 높은 값을 보였으나 BOD/COD비가 0.079로 침출수가 안정화되어 있음을 알 수 있었다. 또한 폐기물의 용출분석결과 COD, BOD 모두 낮은 값을 보였으며 T-N, T-P 각각 7.77, 0.20mg/L의 값을 나타내었고 침출수와 비교하여 모두 현저히 낮은 결과를 보임으로써 폐기물중 생분해성 유기물의 분해가 역시 완료되었음을 알 수 있었다. 이상의 연구 결과 대상 폐기물 매립지는 안정화 단계에 있어 침출수의 발생량은 앞으로 현저하게 감소될 것으로 예측됨으로써, 매립지내로 유입 가능성이 크게 의심되는 지하수의 차단에 의한 침출수 방지 대책 등이 보강될 경우에는 토지의 재이용이 가능할 것으로 판단된다.