• Title/Summary/Keyword: T/C ratio

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Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group

  • Park, Jin Woo;Choi, Ja Sung;Han, Ki Joon;Lee, Sang Heun;Kim, Eui Joo;Cho, Jae Hee
    • The Korean journal of internal medicine
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    • v.33 no.6
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    • pp.1103-1110
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    • 2018
  • Background/Aims: Several epidemiological studies have validated the association of interleukin gene polymorphisms with acute pancreatitis (AP) in different populations. However, there have been few studies in Asian ethnic groups. We aimed to investigate the relationships between inflammatory cytokine polymorphisms and AP as pilot research in a Korean ethnic group. Methods: Patients who had been diagnosed with AP were prospectively enrolled. DNA was extracted from whole blood, and DNA sequencing was subsequently performed. Single-nucleotide polymorphisms (SNPs) of the interleukin $1{\beta}$ (IL1B), interleukin 1 receptor antagonist (IL1RN), and tumor necrosis factor ${\alpha}$ (TNFA) genes of patients with AP were compared to those of normal controls. Results: Between January 2011 and January 2013, a total of 65 subjects were enrolled (40 patients with AP vs. 25 healthy controls). One intronic SNP (IL1RN -1129T>C, rs4251961) was significantly associated with the risk of AP (odds ratio, 0.304; 95% confidence interval, 0.095 to 0.967; p = 0.043). However, in our study, AP was not found to be associated with polymorphisms in the promoter regions of inflammatory cytokine genes, including IL1B (-118C>T, c47+242C>T, +3954C/T, and -598T>C) and TNFA (-1211T>C, -1043C>A, -1037C>T, -488G>A, and -418G>A). Conclusions: IL1RN -1129T>C (rs4251961) genotypes might be associated with a significant increase of AP risk in a Korean ethnic group.

A Study on the Properties of YBaCuO Thin films with Ambient Gas (분위기가스에 따른 YBaCuO 박막의 특성에 관한 연구)

  • Choi, C.S.;Shin, T.H.;Cho, K.S.;Park, G.B.;Kim, Y.J.;Lee, D.C.
    • Proceedings of the KIEE Conference
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    • 1995.07c
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    • pp.1193-1195
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    • 1995
  • The superconducting properties of YBaCuO thin films prepared by pulsed laser deposition(PLD) have been investigated. The x-ray diffraction patterns of the films are substantially different from one another. The YBaCuO thin films manufactured at the 20% of Argon mixture ratio were indicated $T_c$(zero)=88.2 K, $T_c$(onset)=92.1 K, and $J_c=9.0{\times}10^4A/cm^2$(at 77.3K).

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Effect of Forging Condition on the Microstructure and Mechanical Properties in Centrifugal Casted Heat Resistant Steel (원심주조된 내열강의 미세조직 및 기계적성질에 미치는 단조 조건의 영향)

  • Kang, C.Y.;Lee, S.M.;Jo, D.H.;Park, Y.T.;Lee, D.H.;Kim, Y.C.
    • Journal of Power System Engineering
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    • v.13 no.3
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    • pp.47-52
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    • 2009
  • The effect of forging start temperature, forging ratio on the microstructure and mechanical properties of B7B4 steel ware investigated. Microstructure of centrifugal casted B7B4 steel consisted of martensite and ferrite phase. The volume fraction of ferrite increased with increase of forging start temperature and decreased with increase of forging ratio. Tensile strength and hardness decreased with higher of forging start temperature, while impact value and elongation increased with higher of forging start temperature. With increase of forging ratio, tensile strength rapidly increased up to the forging ratio of 30%, and then slowly increased, but elongation was decreased. Hardness and impact value rapidly increased with increase of forging ratio.

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A Study on Shear Capacity of High Strength Lightweight Reinforced Concrete T-Beams (고강도 경량콘크리트를 사용한 철근콘크리트 T 형보의 전단성능)

  • 김진수;김원호;박성무
    • Proceedings of the Korea Concrete Institute Conference
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    • 1993.10a
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    • pp.220-225
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    • 1993
  • This paper is an experimental study on shear capacity of the high strength lightweight reinforced concrete beams with shear-depth ratio between 1.5 and 2.5. Thirteen T & rectangular beams were tested to determine their diagonal cracking and ultimate shear capacity. The major variables are shear span-depth ratio (a/d=1.5, 2.0, 2.5), concrete compressive strength(f'c=210, 24., 270㎏/㎠) and tensile steel ratio( =0.6, 1.2%). Based on results obtained from experiment of high strength lightweight reinforced concrete Beam & normal concrete, the following conclusions were drawn. (1) The shear capacity of high-strength lightweight concrete is less 15% than that of normal concrete under same condition. (2) As the results of Comparing this experimental datas with other various formulas. It is regarded that ACI 318-89 shear strength formula related tensile strength is proper to design formula of shear strength of high-strength lightweight reinforced concrete using lightweight concrete.

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Non-contact mode measurement of high aspect ratio tip (High aspect ratio 팁의 비접촉모드에서의 측정)

  • Shin Y.H.;Han C.S.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.463-464
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    • 2006
  • This paper present experimental results by non-contact mode Atomic Force Microscopy using high aspect ratio tips (HAR-T). We fabricated the carbon nanotube tip based on dielectrophoresis and the carbon nano probe by focused ion beam after dielectrophoretic assembling. In this paper, we measure AAO sample and trench structure to estimate HAR-T's performance and compared with conventional Si tip. We confirmed that results of HAR-T's performance in non contact mode was very superior than conventional tip.

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A Study on the Structure Properties of Plasma Silicon Oxynitride Film (플라즈마 실리콘 OXYNITRIDE막의 구조적 특성에 관한 고찰)

  • 성영권;이철진;최복길
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.5
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    • pp.483-491
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    • 1992
  • Plasma silicon oxynitride film has been applied as a final passivation layer for semiconductor devices, because it has high resistance to humidity and prevents from alkali ion's penetration, and has low film stress. Structure properties of plasma silicon oxynitride film have been studied experimentally by the use of FT-IR, AES, stress gauge and ellipsometry. In this experiment,Si-N bonds increase as NS12TO/(NS12TO+NHS13T) gas ratio increases. Peaks of Si-N bond, Si-H bond and N-H bond were shifted to high wavenumber according to NS12TO/(NS12TO+NHS13T) gas ratio increase. Absorption peaks of Si-H bond were decreased by furnace anneal at 90$0^{\circ}C$. The atomic composition of film represents that oxygen atoms increase as NS12TO/(NS12TO+NHS13T) gas ratio increases, to the contrary, nitrogen atoms decrease.

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Influence of Temperature and Relative Humidity on the Rearing Performance and Disease Incidence in CSR Hybrid Silkworms, Bombyx mori L.

  • Kumari, K.M.Vijaya;Rajan, R.K.;Himantharaj, M.T.;Nataraj, B.;Rekha, M.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.3 no.2
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    • pp.113-116
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    • 2001
  • Fifth instar larvae of the new bivoltine hybrid (CSR2 ${\times}$ CSR5) were reared under different temperature and humidity viz., $20^{\circ}C$ and 85 ${pm}$ 5% R.H (T1), $25^{\circ}C$ and 70 ${pm}$ 5% R.H (T2-Optimum), $30^{\circ}C$ and 80% ${pm}$ 5 R.H (T3) and $35^{\circ}C$and 50 ${pm}$ 5% R.H (T4). The cocoon yield, cocoon characters and disease incidence were studied in normal (non infectious source, i.e control) rearing as well as in 1% infectious source of rearing. The results indicated that V instar larval duration was prolonged and cocoon weight was improved in T1. ERR and shell ratio were significantly improved and disease incidence was minimised in T2. Further significant difference was observed among the treatments with regard to spread of diseases.

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Optimizing the mix design of pervious concrete based on properties and unit cost

  • Taheri, Bahram M.;Ramezanianpour, Amir M.
    • Advances in concrete construction
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    • v.11 no.4
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    • pp.285-298
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    • 2021
  • This study focused on experimental evaluation of mechanical properties of pervious concrete mixtures with the aim of achieving higher values of strength while considering the associated costs. The effectiveness of key parameters, including cement content, water to cement ratio (W/C), aggregate to cement ratio (A/C), and sand replacement was statistically analyzed using paired-samples t-test, Taguchi method and one-way ANOVA. Taguchi analysis determined that in general, the role of W/C was more significant in increasing strength, both compressive and flexural, than cement content and A/C. It was found that increase in replacing percent of coarse aggregate with sand could undermine specimens to percolate water, though one-way ANOVA analysis determined statistically significant increases in values of strength of mixtures. Cost analysis revealed that higher strengths did not necessarily correspond to higher costs; in addition, increasing the cement content was not an appropriate scenario to optimize both strength and cost. In order to obtain the optimal values, response surface method (RSM) was carried out. RSM optimization helped to find out that W/C of 0.40, A/C of 4.0, cement content of about 330 kg/m3 and replacing about 12% of coarse aggregate with sand could result in the best values for strength and cost while maintaining adequate permeability.

Interaction of Cu(II)-meso-tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2,3,4) with Native and Synthetic Polynucleotides Probed by Polarized Spectroscopy

  • Lee, Mi-Jin;Lee, Gil-Jun;Lee, Dong-Jin;Kim, Seog-K.;Kim, Jong-Moon
    • Bulletin of the Korean Chemical Society
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    • v.26 no.11
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    • pp.1728-1734
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    • 2005
  • The interactions of Cu(II)-meso-Tetrakis(n-N-methylpyridiniumyl)porphyrin (n = 2,3,4), respectively referred to as o-, m- and p-CuTMPyP, and DNA, poly$[d(A-T)_2]$ and poly$[d(G-C)_2]$ were investigated by circular and linear dichroism (CD and LD). In the o-CuTMPyP case, in which the rotation of the pyridinium ring is prevented, the shape of the CD spectrum when associated to DNA and poly$[d(A-T)_2]$ resembles and is characterized by a positive band at a low drug to DNA concentration ratio (R ratio) and is bisignate at a high R ratio. The former CD spectrum shape has been attributed to porphyrin that is bound monomerically outside of DNA while the latter can be attributed to those that are stacked. When o-CuTMPyP is bound to poly$[d(G-C)_2]$, the excitonic CD appeared at a relatively high R ratio. In contrast, a characteristic negative CD band in the Soret region was apparent for both m- and p-CuTMPyP when bound to DNA and poly$[d(G-C)_2]$ at the low R ratios, indicating that the porphyrin molecule intercalates. However, the DNA is bent near the intercalation site and the plane of the porphyrin molecule tilts relative to the DNA helix axis, as judged by the magnitude of the reduced LD. Various stacking patterns were identified by the shape of the CD spectrum for m- and p-CuTMPyP when bound to poly$[d(A-T)_2]$. Three species for the former complex and two for the latter complex were found which may reflect the extent of the stacking.