• Proceedings of the KOSOMBE Conference
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• v.1993 no.05
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• pp.51-53
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• 1993

We have developed a monoleaflet polymer valve in order to be used as an inlet valve of the ventricular assist device, because it could help to improve the fluid dynamic characteristics in the ventricle. Mean systolic transvalvular pressure drops were measured for the monoleaflet polymer valve and their results were compared wi th that of the mechanical valve.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.3
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• pp.513-523
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• 2002

Purpose : This study aimed to investigate the effect of foot massage on sleep, vital signs and fatigue in the elderly who live in their Home. Method: Data were collected from 20 elderly who live in the Seoul-Kyunggi province area by convenience sampling and analyzed the change of sleep and sleep satisfaction, vital signs(pulse, respiration, systolic and diastolic blood pressure) and general fatigue between pre and post foot massage using Paired t- test at 0.05 of significance level. Result: There were very significant difference in the sleep and fatigue between pre and post foot massage. Conclusion: Foot massage can improve the sleep and decrease fatigue, therefore we recommend to use foot massage as a effective sleep related nursing intervention in the elderly who live in their home.

• The Korean Journal of Rehabilitation Nursing
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• v.6 no.2
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• pp.173-182
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• 2003

Purpose: This study was conducted to evaluate the effects of aerobic exercise on health status with essential hypertension. Method: A non-equivalent control group design was used. For the experimental group, aerobic exercise was given by researcher at one health center in Daegu. Test for hypothesis was done by $X^2$-test t-test, paired t-test, and unpaired t-test. Result: There were significant differences in systolic, diastolic, and MAP between two groups. There were significant differences in body weight, BMI, and body composition between two groups. Hypothesis 3 was partially supported that the score of health status and physical function of experimental group were significantly higher than that of control group. Conclusion: Findings indicated that this study would contribute to application of aerobic exercise as nursing intervention for the people with high blood pressure.

• Archives of Pharmacal Research
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• v.17 no.3
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• pp.150-153
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• 1994

Ethanolic extract of Daucus carota (DC) at the dose of 10-100 mg/kg caused a dose-dependent fall in systolic and diastolic arterial blood pressure in nomotensive anesthetized rats. These effects were not blocked by atropine (1 mg/kg) and pretratment with DC did not alter the pressor response to norepinephrine indicating that cardiovascular effects of DC are independent of cholinergic or adrenergic recptors involvement. In spontaneously beating guinea-pig paired atria, DC induced a concentration-dependent (03-5 mg/ml) decrease in force and rate of atrial contractions. In rabbit thoracic aorta, DC caused inhibition of $K^+$-induced contractions at similar concentrations. These results suggest that the extract may exhibit $Ca^{2+}$ channel blocking-like direct relaxant action on cardiac and smooth muscle preperations and this action may be responsible for its hypotensive effect observed in the in vivo studies.

• Korean journal of food and cookery science
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• v.13 no.1
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• pp.47-55
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• 1997

The hypoglycemic and hypotensive effects of Polygonatum odoratum in non-insulin dependent diabetes metlitus (NIDDM) patients were investigated in this study. Sixty five NIDDM patients were divided into two groups: hospital diet (HD), Polygonatum odorat um diet (PD). HD group was provided with the diabetic diet used in a hospital and PD group consumed the Polygonatum odoratum added to the HD. The index of obesity, the level of fasting blood pressure (systolic and diastolic), fasting and postprandial blood glucose of NIDDM patients of the PD group were significantly lowered after the experimental period of 4 weeks. The levels of the plasma glucose, lipid and index of obesity was measured. The tendency of elevating the level of HDL-cholesterol and lowering the levels of triglyceride, LDL-cholesternl and total cholesternl were also noticed in NIDDM patients of the PD group. The results showed that Polygonatutn odoratum could be an important dietary source to control hyperglycemia and hypertension and that the plant could be recommended as a preventive or therapeutic agent for NIDDM patients.

• Journal of Veterinary Clinics
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• v.40 no.1
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• pp.50-55
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• 2023

A 10-year-old spayed female Cocker spaniel weighing 6.64 kg was presented with a sign of syncope. Electrocardiographic findings revealed pathologic atrioventricular (AV) block alternating 3rd degree AV block, non-responsive to atropine. Before pacemaker implantation, several anti-hypertensive medications were administered, but there was no improvement. After pacemaker implantation, the heart rate and systemic arterial systolic blood pressure were immediately improved. This is the first report on the resolution of an AV block and malignant systemic hypertension after a pacemaker implant in veterinary medicine.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.3
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• pp.37-46
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• 2024

PURPOSE: This study examined sarcopenia in middle-aged men aged 40 to 49 years. METHODS: The study design was a nationwide cross-sectional study involving 1,564 participants. The participants were divided into two groups based on their skeletal muscle mass index scores, with 36 and 1,528 individuals classified into the sarcopenia and normal groups, respectively. The variables examined included age, height, weight, body mass index (BMI), waist circumference, skeletal muscle mass index, and systolic and diastolic blood pressure. The results from blood tests included fasting glucose, triglycerides, and total cholesterol levels. The smoking and drinking status were also recorded. RESULTS: The anthropometric variables, such as weight, BMI, and waist circumference, revealed significant differences between the two groups (p < .05), except for height (p > .05). In addition, total cholesterol in the laboratory test and drink status were significant between the two groups (p < .05). CONCLUSION: This study identified significant determinants for sarcopenia among community-dwelling middle-aged men.

• Clinical and Experimental Pediatrics
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• v.53 no.1
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• pp.72-79
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• 2010

Purpose: Left ventricular (LV) hypertrophy and impaired diastolic function may occur early in systemic hypertension. Diastolic dysfunction is associated with increased cardiovascular risk. Tissue Doppler imaging (TDI)-derived tissue velocity and strain rate are new parameters for assessing diastolic dysfunction. The aim of this study is to determine whether TDI and strain rate imaging (SRI) would improve the ability to recognize early impaired diastolic and systolic functions compared with conventional echocardiography in hypertensive adolescents. Methods: We included 38 hypertensive patients with systolic blood pressure above 140 mmHg or diastolic blood pressure above 90 mmHg. Ejection fraction and myocardial performance index (MPI) were estimated by conventional echocardiography. Peak systolic myocardial velocity, early diastolic myocardial velocity (Em), and peak late diastolic myocardial velocity (Am) were obtained by using TDI and SRI. Results: In the hypertensive group, interventricular septal thickness was significantly increased on M-mode echocardiography. Em/Am was significantly decreased at the mitral valve annulus. Among hypertensive subjects, the E strain rate at basal, mid, and apex was significantly decreased. Systolic strain was significantly decreased at the septum in the hypertensive group. Conclusion: Strain rate might be a useful new parameter for the quantification of both regional and global LV functions and could be used in long-term follow up in hypertensive patients. Early identification by SRI of subjects at risk for hypertensive and ventricular dysfunction may help to stratify risk and guide therapy. Further studies, including serial assessment of LV structure and function in a larger number of adolescents with hypertension, is necessary.

• Journal of Digital Convergence
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• v.12 no.4
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• pp.349-356
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• 2014

This research is aimed to prove if harmful effects of smoking, as the main reason for recently elevated blood vessel disease, could be reduced by aerobic exercise, and identify the positive effects of the aerobic exercise on smokers' blood vessel health(blood pressure, pulse pressure, and blood vessel elasticity. Experiments were performed on 40 male smokers aged between 40 and 55, which was equally divided into two groups of Aerobic Exercise Group (AEG) and Non Exercise Group (NEG). After measuring each group's blood pressure, pulse pressure, and blood vessel elasticity, AEG practiced aerobic exercise program for 50 minutes for each trial, three times a week, sustaining 12 weeks while NEG continued daily-life patterns without any special treatment. In 12 weeks, blood pressure, pulse pressure, and blood vessel elasticity of both groups were measured as the same way. As a result, the difference of systolic blood pressure between the two groups was not significant, while that of diastolic blood pressure was meaningful. The difference of pulse pressure between the two groups was meaningful, and that of blood vessel elasticity was also meaningful in all measuring points including left hand, right hand, left foot and right foot. As a consequent, it was found that aerobic exercise had positive effects on middle aged male smokers' blood vessel health.

• Journal of Ginseng Research
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• v.45 no.5
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• pp.546-554
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• 2021

Background: Diabetes mellitus and hypertension often occur together, amplifying cardiovascular disease (CVD) risk and emphasizing the need for a multitargeted treatment approach. American ginseng (AG) and Korean Red Ginseng (KRG) species could improve glycemic control via complementary mechanisms. Additionally, a KRG-inherent component, ginsenoside Rg3, may moderate blood pressure (BP). Our objective was to investigate the therapeutic potential of coadministration of Rg3-enriched Korean Red Ginseng (Rg3-KRG) and AG, added to standard of care therapy, in the management of hypertension and cardiometabolic risk factors in type-2 diabetes. Methods: Within a randomized controlled, parallel design of 80 participants with type-2 diabetes (HbA1c: 6.5-8%) and hypertension (systolic BP: 140-160 mmHg or treated), supplementation with either 2.25 g/day of combined Rg3-KRG + AG or wheat-bran control was assessed over a 12-wk intervention period. The primary endpoint was ambulatory 24-h systolic BP. Additional endpoints included further hemodynamic assessment, glycemic control, plasma lipids and safety monitoring. Results: Combined ginseng intervention generated a mean ± SE decrease in primary endpoint of 24-h systolic BP (-3.98 ± 2.0 mmHg, p = 0.04). Additionally, there was a greater reduction in HbA1c (-0.35 ± 0.1% [-3.8 ± 1.1 mmol/mol], p = 0.02), and change in blood lipids: total cholesterol (-0.50 ± 0.2 mmol/l, p = 0.01), non-HDL-C (-0.54 ± 0.2 mmol/l, p = 0.01), triglycerides (-0.40 ± 0.2 mmol/l, p = 0.02) and LDL-C (-0.35 ± 0.2 mmol/l, p = 0.06) at 12 wks, relative to control. No adverse safety outcomes were observed. Conclusion: Coadministration of Rg3-KRG + AG is an effective addon for improving BP along with attaining favorable cardiometabolic outcomes in individuals with type 2 diabetes. Ginseng derivatives may offer clinical utility when included in the polypharmacy and lifestyle treatment of diabetes. Clinical trial registration: Clinicaltrials.gov identifier, NCT01578837;