• Journal of the East Asian Society of Dietary Life
• /
• v.3 no.2
• /
• pp.29-40
• /
• 1993

A variety of studies show that a centraized rather than a generalized pattern of subcutaneous fat distribution is more directly associated with disorers of carbohydrate and lipid metabolism, as possibly hypertension, This study was an attempt to observe the relationship of body fat distribution, blood lipids, blood pressure and exercise in 85 healthy men and women. Within this group there was a gradation of fat distribution progressing from LBSO and UBSO defined on the basis of WHR. This paper reports the relationship of body fat distribution defined by WHR to plasma glucose, lipids, blood pressure, and exercise in this population. Although the obesity indices(RBW and BMI) were slightly higher in the UBSO group, significant differences existed between UBSO and LBSO groups with respect to WHR blood pressure, and total cholesterol concentration in female. WHR values were substantially different and this was primarily due to greater degrees of differences in waist as opposed to hips circum ference. Although no significant differences existed between UBSO and LBSO groups with respect to age, body weight, and hips circumference, energy intake, total cholesterol, LDL-cholesterol and WHR values were substantially different in male. Positive, significant correlations were found between WHR and both systolic and diastolic blood pressure and between WHR and the total plasma cholesterol concentration and age. When 26 pairs of exercise and nonexercise groups were matched according to sex, age and body weight, blood pressure and blood lipids were significantly lower in the exercise groups than those in the nonexercise groups. In conclusion, these findings suggest that an altered blood lipid profiles will manifast in men and women with upper body obese. Furthermore these findings suggest that exercise and physical activity may be beneficial for controlling blood lipids and blood pressure in healthy adults.

• Korean Journal of Rural Living Science
• /
• v.7 no.1
• /
• pp.23-29
• /
• 1996

The purpose of this study is to observe the relationship between smoking and control factors to blood pressure, such as sodium and potassium levels of dietary intake and serum in 67 rural university male students(smoker: 35 persons, non smoker: 32 persons). 3-day dietary record and blood sampling were conducted for measurements of the levels of dietary intake and serum. The results were as follows: 1) There are no significance between smokers and non-smokers in height, weight, and BMI. 2) Mean systolic and diastolic blood pressure of smokers and non-smokers were $131.33\pm93.75mmHg, \;119.37\pm80.62mmHg, $ respectively. Blood pressure of smoker was higher than that of non-smokers(p＜0.05). 3) There was no significant difference between smoker and non smoker in dietary potassium intake but dietary sodium intake and Na/K ratio of smoker were higher than those of non-smokers(p＜0.05, p＜0.05). And significant correlation was found between dietary sodium intake and blood pressure of smokers(p＜0.05). 4) Smokers of optimum gustation of salt(0.52%) was higher than that of non-smokers(0.49%). Even though blood pressure of smokers was not critical level, if they smoke continuosely until middle age, their blood pressure will be increased by smoking. The results of this study suggest that no smoking education program for smokers including the information about desirable food habits for prevention of hypertension should be developed.

• The Journal of Korean Medicine
• /
• v.21 no.1
• /
• pp.62-67
• /
• 2000

Background and Purpose: Sybsun-points are located at the tips of all fingers, 0.1chon from the finger nails, totaling 10 points on both hands. These points have been used for emergency care, fainting, epilepsy, cerebrovascular accidents, hypertension, unconsciousness, high fever etc. The most common technique is bleeding with a needle at these points. Hypertension and fever are the main factors for stroke patients’progress. We investigated whether venesection at Sybsun-points has effects on blood pressure and body temperature in stroke patients. Materials and Methods: 79 stroke patients were enrolled in this study from 1 Jan. 1999 to 30 Sep. 1999. All of them were admitted in Kyunghee University, Hospital of Oriental Medicine. Among them, 62 patients were hypertensive people, 17 were normal. Among the hypertensive patients, 27 were stage 1,20 were stage 2, 15 were stage 3 by classification of JNC 1997. All of the hypertensive patients had been taking drugs, while the normal group did not. From 2pm to 3pm, every 30 minutes we checked patients' blood pressure and body temperature by 24ABPM and tympanic thermometer. After 30 minutes passed, we phlebotomized patients Sybsun-points with Samneung needle 2-3cc of blood. Right after the bleeding, we checked blood pressure and body temperature. After the bleeding, for the next hour and a half, we checked each patient’s blood pressure and body temperature every thirty minutes, or a total of three times. We compared the blood pressure and the body temperature before and after treatment(p<0.05). Results: 1. Venesection at Sybsun-points significantly decreased systolic blood pressure on stage 3 hypertensive patients(p<0.0l). 2. Venesection at Sybsun-points significantly decreased diastolic blood pressure on stage 3 hypertensive patients(p<0.05) 3. Venesection at Sybsun-points had no effect on the change of body temperature. Conclusions: Though further study is needed, our findings suggest that Venesection at Sybsun-points may alleviate hypertension in stroke patients.

• Journal of Korean Medicine for Obesity Research
• /
• v.6 no.1
• /
• pp.81-92
• /
• 2006

Objectives : Recent studies have provided some clues with regard to the relationship existing between uncoupling proteins (UCPs) and blood pressure in animal experiments. In an attempt to determine the genetic polymorphisms of UCPs that are associated with blood pressure in humans, we have analyzed genetic polymorphisms in members of the UCP family, including UCP1, UCP2 and UCP3. Methods : In this study, we assessed the association between UCP genotypes and systolic blood pressure (SBP) and diastolic blood pressure (DBP), in a population comprised of 832 Korean female subjects, using a general linear model, which was adjusted for both age and BMI. Results : Among 14 SNPs and the haplotypes constructed from them, haplotype3 of UCP1 (UCP1-ht3) evidenced significant associations with SBP (P=0.0053) and DBP (P=0.0130). However, this haplotype was not significantly associated with obesity phenotypes, including BMI or fat mass (P>0.05), thereby suggesting that its association with blood pressure was not mediated by obesity phenotypes. Conclusions : The source of variations in SBP were determined to occur in the following order: BMI (12.8 %), age (1.2 %) and UCP1-ht3 (1.1 %). Although BMI appears to exert greater effects on blood pressure, the UCP1-ht3 genotype was also found to exert a significant effect.

• Journal of the Korea Convergence Society
• /
• v.10 no.11
• /
• pp.209-215
• /
• 2019

The most important personal health care in digital health care is a very important issue mainly for chronic diseases. Therefore, it is important to develop a simple wearable device for real-time health management. Existing blood pressure estimation wearable devices use PPG characteristics to analyze PTT and propose blood pressure estimation algorithms. However, the influencing factors of the algorithm such as the reproducibility of PPG, whether to apply various PTTs, and variables generated from the physical differences of the measurers are actually very complex. Therefore, in this study, the correlation between PTT, SBP, and DBP was analyzed, and it was designed to use PPG sensors for device miniaturization. The blood pressure estimation algorithm took into account differences in PPG, heart rate, and personal variables.

• Journal of Pharmacopuncture
• /
• v.26 no.4
• /
• pp.298-306
• /
• 2023

Objectives: Cucumis sativus L. (C. sativus) is vegetable commonly used for managing blood pressure and often consumed in combination with standard antihypertensive therapy, despite lack of scientific evidence supporting their use. Combination of herbs and standard medication could have positive or negative effects. Therefore, this study aimed to evaluate the antihypertensive activity of C. sativus and the combined effect with losartan in the hypertensive rat model induced by angiotensin II. Angiotensin II is a component of the renin-angiotensin-aldosterone system that, upon binding to its receptor, constricts blood vessels leading to elevation of blood pressure. Methods: In an antihypertensive study, rats received C. sativus orally at doses of 9, 18, 27, and 36 mg/kg (full dose); while in a combination study, animals received losartan 2.25 mg/kg combined by either with C. sativus 9 or 18 mg/kg. The standards group received losartan 2.25 mg/kg or 4.5 mg/kg (full dose). Results: Blood pressure was measured using the tail-cuff method. C. sativus significantly attenuated angiotensin II-induced hypertension as observed in groups receiving C. sativus at 9, 18, 27, and 36 mg/kg at 30 minutes after induction showed the average change (Δ) of systolic blood pressure (SBP) and diastolic blood pressure (DBP) with respect to time zero were 28.8/18.3, 24.8/15.8, 22.8/15.5, and 11.5/9.0 mmHg, respectively. Whereas the average change (Δ) of SBP and DBP in the rats receiving the combination of half doses of C. sativus and losartan were 8.8/9.0 mmHg, respectively. These diminished effects were better than a full dose of C. sativus and comparable with a full dose of losartan (6.5/7.8 mmHg). Conclusion: The present findings indicate that C. sativus dose-dependently blocks blood pressure elevation induced by angiotensin II. The combination of half dose of C. sativus and losartan has an additive effect in lowering blood pressure.

• The Journal of Korean Medicine
• /
• v.45 no.1
• /
• pp.251-256
• /
• 2024

Objectives: The purpose of this study was to report the short-term blood pressure-lowering effects observed in a patient with malignant hypertension through slow breathing maneuver with heart rate variability(HRV) biofeedback. Methods: Biofeedback sessions, totaling 13, each lasting 10 minutes, were administered. Blood pressure was measured pre and post-treatment, as well as thrice daily at 10 am, 4 pm, and 8 pm. Systolic blood pressure(SBP), diastolic blood pressure(DBP), and pulse rate were recorded for comparative analysis. Results: Before biofeedback, the average SBP, DBP, and pulse rate were 227.2±18.3, 135.2±11.0, and 104.4±5.3, respectively. Immediately post-biofeedback, these values changed to 213.7±15.2, 126.9±8.5, and 99.2±3.6. However, sustained long-term blood pressure reduction was not observed. Conclusions: The findings suggest that biofeedback therapy induces a short-term reduction in blood pressure in cases of malignant hypertension, potentially associated with autonomic nervous system regulation. Integrating biofeedback with other Korean medicine treatments, such as acupuncture or moxibustion, may offer a comprehensive approach for managing malignant hypertension.

• Korean Circulation Journal
• /
• v.54 no.2
• /
• pp.93-104
• /
• 2024

Backgrounds and Objectives: This study aimed to evaluate the applicability and precision of a ring-type cuffless blood pressure (BP) measurement device, CART-I Plus, compared to conventional 24-hour ambulatory BP monitoring (ABPM). Methods: Forty patients were recruited, and 33 participants were included in the final analysis. Each participant wore both CART-I Plus and ABPM devices on the same arm for approximately 24 hours. BP estimation from CART-I Plus, derived from photoplethysmography (PPG) signals, were compared with the corresponding ABPM measurements. Results: The CART-I Plus recorded systolic blood pressure (SBP)/diastolic blood pressure (DBP) values of 131.4±14.1/81.1±12.0, 132.7±13.9/81.9±11.9, and 128.7±14.6/79.3±12.2 mmHg for 24-hour, daytime, and nighttime periods respectively, compared to ABPM values of 129.7±11.7/84.4±11.2, 131.9±11.6/86.3±11.1, and 124.5±13.6/80.0±12.2 mmHg. Mean differences in SBP/DBP between the two devices were 1.74±6.69/-3.24±6.51 mmHg, 0.75±7.44/-4.41±7.42 mmHg, and 4.15±6.15/-0.67±5.23 mmHg for 24-hour, daytime, and nighttime periods respectively. Strong correlations were also observed between the devices, with r=0.725 and r=0.750 for transitions in SBP and DBP from daytime to nighttime, respectively (both p<0.001). Conclusions: The CART-I Plus device, with its unique ring-type design, shows promising accuracy in BP estimation and offers a potential avenue for continuous BP monitoring in clinical practice.

• Journal of Trauma and Injury
• /
• v.18 no.2
• /
• pp.161-171
• /
• 2005

Background: The management of hepatic injuries has changed dramatically during the past two decade after the technologic breakthroughs in radiologic imaging techniques. Recently, the non-operative management of blunt hepatic trauma has become the standard of care in hemodynamically stable patients. We reviewed our experience of the non-operative management of blunt hepatic trauma. And the purpose of this study was to examine the prognostic factors and indicators affecting the decision for treatment modality of emergent hepatic trauma. Methods: The medical records of 84 patients who were treated for blunt hepatic injury at Masan Samsung Hospital from January 2002 to December 2003. The patients were divided two groups, non-operative(Non-OP) and operative(OP), according to the treatment modality. The two groups were compares for age, sex, mechanism of injury, grade of liver injury scale, combined injury, systolic blood pressure, pulse rate, hemoglobin, hematocrit, WBC count, S-GOT, S-GPT, ALP, transfusion amount during initial 24 hours, amount of infused crystalloid fluid, length of ICU stay, length of ward care, morbidity and mortality. The grade of the liver injury were determined by using the organ injury scale(OSI). Results: Among the 84 patients, 46 cases(54.8%) were managed non-surgically, and 3 cases of Non-OP group were treated by transarterial embolization. Between the two groups, there were significant difference in age, injury grade, combined injury, hemoglobin, hematocrit, initial systolic blood pressure, amount of infused crystalloid fluid, amount of transfusion during the first 24 hours, and length of ICU care, morbidity and mortality.(p<0.05) The overall mortality rate was 8.3%, but 2.2% mortality in the non-operative group. Conclusion: Non-operative management may be considered as a first choice in hemodynamic stable patients with blunt liver trauma. The reliable indicators affecting the treatment modality of blunt hepatic trauma were systolic BP, Hb, Hct, amount of infused crystalloid fluid, amount of transfusion during the first 24 hours, liver injury grade and combined injury. Strict selection of treatment madality and aggresive monitoring with intensive care unit were more important.

• Korean Journal of Community Nutrition
• /
• v.7 no.6
• /
• pp.749-761
• /
• 2002

This study investigated the anthropometric and biochemical indices, and the health and nutritional factors influencing the two indices among 194 middle-aged and elderly subjects (108 middle-aged and 86 elderly) residing in a medium sized city for more than 10 years. In the examination of their dietary habits, 8.3% of the middle-aged subjects and 14.0% of the elderly subjects had two meals a day, and more female subjects had two meals per day. Of the subjects who ate meals at regular times, 75.0% were middle-aged and 79.1% were elderly, and the degree of irregularity of meals was greater for female subjects. The study of the dietary behavior of the subjects indicated that 71.3% and 66.3% of the middle-aged and elderly, respectively responded that the amount of food in each meal was sufficient. The subjects ate alone comprised 19.7% of the middle-aged females and 31.5% of the elderly females. The prevalence of smoking among the subjects was 28.1% for the middle-aged, 18.8% for the elderly male and 7.4% for the elderly females. The percentage of the subjects who drank alcohol was 34.4% of the middle-aged males and 13.2% of the middle-aged females. Slightly less than half of the subjects exercised more than once a week, with the male subjects showing a higher rate than the female subjects. The average body mass indices (BMI) were 24.5 and 24.6 for the middle-aged male and female, respectively, and 22.6 and 24.0 for the elderly male and female, respectively. BMI assessment showed that underweight subjects (BMI ＜ 20) comprised 3.7% of the middle-aged, 14.0% of the elderly, and that 40.7% of the middle-aged and 24.4% of the elderly were overweight (25 ＜ BMI ＜ 30) , and 0.9% of the middle-aged and 1.2% of the elderly were classified as obese (BMI $\geq$ 30) . A waist/hip ratio (WHR) greater than 0.8 was found in 89.5% of the middle-aged females and 90.7% of the elderly females, showing high abdominal fat deposition in the majority of females. The average systolic blood pressure of females was 121.1 $\pm$ 17.1 mmHg for the middle-aged and 129.6 $\pm$ 21.3 mmHg for the elderly subjects. The systolic blood pressures showed a significantly difference between the two age groups. Those defined as anemic subjects based on hemoglobin values comprised 13.0% of the middled-aged group and 16.3% of the elderly group. There was a tendency for higher fasting glucose levels among the elderly subjects. An increase in total plasma cholesterol levels with age was shown. The female subjects had higher cholesterol levels than the males'The study of the correlation between the daily habits and health status showed that the amount of food eaten at each meal, the frequency of eating out, and the use of dietary supplements appeared to influence BMI, WHR, the plasma triglyceride and plasma cholesterol levels; omitting one meal had a positive correlation with the systolic blood pressure and plasma cholesterol. These results suggest that desirable dietary habits and concerns for health are contributing factors for maintaining good health, as indicated by normal blood lipid levels.