• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.37 no.3
• /
• pp.75-81
• /
• 2014

To establish a new creative economy, the worldwide efforts have been made to wriggle out the old economic paradigm after the financial crisis of 2008. When it comes to the limitation of the viability. the start up companies have a high risk of failure. Therefore business incubator (BI) should carry out the role to improve their viability. As for the maximization of the effect on the business incubating services as move in companies, it is important for BI to increase the level of business incubating services by the systemic and scientific measurement. This study showed that the quality of the BI center services was measured by Kano analysis and the previous research as follows. First, BI quality attribute by Timko's customer satisfaction came out into the attractive qualities on the 14 items that amount to the 70% of 20 business incubating services items. It is desirable to perform the strategy for the satisfaction. Secondly, basic business incubating services were interpreted as the one-dimensional quality like incubating spaces, parking facilities, security facilities, industry technology development funds, and incubating managers. Finally, training and educational service was recognized as indifferent quality. Futhermore, the improvement and the limitation of this study as well as the interpretation of analysis results are also provided.

• YAKHAK HOEJI
• /
• v.38 no.2
• /
• pp.191-196
• /
• 1994

Higenamine is a tetrahydroisoquinoline alkaloid which was isolated as a cardiotonic principle from Aconiti tuber. 1.v. injection of higenamine was reported to increase the cardiac output and heart rate and to decrease the blood pressure and the systemic vascular resistance presumably by stimulating the adrenergic ${\beta}-receptors$. The anti-platelet and anti-thrombotic effects of higenamine were investigated in this paper. Higenamine(0.5 mg/ml) showed mild inhibitory effect against collagen induced platelet aggregation in vitro and the inhibito교 effect was increased with the pre-incubation$(5{\sim}30\;min)$ of platelet rich plasma(PRP) with higenamine. With the 30 min incubation, the platelet aggregation was almost completely inhibited. And the oral administration of higenamine$(50{\sim}200\;mg/kg)$ enhanced the survival in the mouse model of thrombosis and that of endotoxic shock. The anti-thrombotic and anti-septic effects of higenamine thus appear to be due to the ${\beta}-agonistic$ and the anti-platelet effects of this compound.

• Journal of East-West Nursing Research
• /
• v.20 no.2
• /
• pp.145-153
• /
• 2014

Purpose: The purposes of this study were to evaluate the degree of social support, self-esteem, and motivation for rehabilitation in stroke patients and examine correlations between activities of daily living and study variables. Furthermore, this study explored factors that influence on activities of daily living. Methods: The study population was 192 stroke patients admitted in two general hospitals and two rehabilitation hospitals in M city. We collected the data using the structured questionnaires from July 11 to September 30, 2013. Results: The higher degree of social support, self-esteem, motivation for rehabilitation, the higher performance level for activities of daily living. Influencing factors of activities of daily living in the participants were motivation for rehabilitation(${\beta}$=.32, p<.001) and social support(${\beta}$=.31, p<.001). The model explained 45.9% of the variance. Conclusion: This study shows that intrinsic motivation of change in stroke patients themselves, a strong will to return to society and social supports are important factors on activities of daily living. Therefore, it is needed to develop a systemic nursing intervention improving activities of daily living in stroke patients through positive social support from patients' family members and health care providers.

• The Bulletin of The Korean Astronomical Society
• /
• v.39 no.2
• /
• pp.58.1-58.1
• /
• 2014

Energetic gas outflows from active galactic nuclei (AGNs) may have a crucial role in galaxy evolution. In this contribution, we present a census of ionized gas outflows using a large sample (~23,000) of local (z < 0.1) type-2 AGNs selected from the Sloan Digital Sky Survey DR 7. By measuring the velocity offset of narrow emission lines, i.e., [O III] ${\lambda}5007$ and the Balmer lines, with respect to the systemic velocity measured from the stellar absorption lines, we find ~47% of AGNs showing an [O III] line-of-sight velocity offset ${\geq}20km\;s-1$. The fraction in type-2 AGNs is similar to that in type-1 AGNs after considering the projection effect. AGNs with larger [O III] velocity offsets, in particular with no or weak $H{\alpha}$ velocity offsets, tend to have higher Eddington ratios, implying that the [O III] velocity offset is related to on-going black hole activity. Also, we find the different distributions of the host galaxy inclination between the AGNs with blueshifted [O III] and the AGNs with redshifted [O III], supporting the model of biconical outflow with dust obscuration. Meanwhile, for ~3% of AGNs, [O III] and $H{\alpha}$ exhibit comparable large velocity offsets, suggesting a more complex gas kinematics than decelerating outflows in the narrow-line region.

• Korean Journal of Childcare and Education
• /
• v.16 no.5
• /
• pp.27-45
• /
• 2020

Objective: The purpose of this study is to develop a music making program that utilizes the characteristics of the picture books medium through the ADDIE model so that teachers can easily apply it to children, and to determine whether it affects children's musical aptitude and music creativity. Methods: The Participants of the study were 42 five-year-old children attending a daycare in Seoul, of which 20 were in the experimental group and 22 in the comparative group. The experimental group participated in a music production program using picture books, and during the same period, the comparison group participated in music activities suggested by the Nuri Course. Using the SPSS 22.0 program, average, standard deviation, independent sampling t-test, and ANCOVA(Analysis of Covariance) were calculated. Results: The music making program using picture books improved children's rhythm and tone which are the sub-items of music aptitude. The music making program enhanced children's music flexibility, music creativity, music logic which are the sub-items of music creativity. Conclusion/Implications: The music making program presented systemic teaching-learning method with which teachers explained the modeling and practiced from simple activities to various activities repeatedly in order to make teachers approach music making more easily. It is recommendable to make the music making program by using I-pad and computers.

• Child Health Nursing Research
• /
• v.23 no.1
• /
• pp.10-18
• /
• 2017

Purpose: The purpose of this study was to identify personal, contextual, and cognitive factors influencing the career preparation behavior of Korean nursing students. In this study, an examination was done of the fitness of a path model for the relationship among these factors based on the social cognitive career theory. Methods: The participants were 413 nursing students in South Korea. Data were collected using self-report questionnaires that included self-esteem, social support, self-efficacy, outcome expectation, career decision level, and career preparation behavior. Data were analyzed using descriptive statistics, Pearson correlation analysis, and path analysis. Results: The factors influencing career preparation behavior were self-efficacy, career decision level, self-esteem, outcome expectation, and social support. The factors influencing career decision level were self-efficacy, outcome expectation, self-esteem, and social support. Conclusion: The findings indicate that self-efficacy is an important factor influencing the career behavior of Korean nursing students. Nurse educators should consider personal, contextual, and cognitive factors of nursing students and develop systemic career guidance programs to help nursing students' career preparation behavior.

• Toxicological Research
• /
• v.13 no.3
• /
• pp.237-245
• /
• 1997

As the development of a pharmaceutical product is a dynamic process which involves continuousfeed-back between non-clinical and clinical studies, the integration of pharmacokinetics into toxicity testing became increasingly important in recent years. Toxicokinetic measurements in the toxicity studies is considered to be an important scientific approach in the interpretation of the toxicology findings and the promotion of rational study design development. Primarily this research project was conducted to determine the systemic exposure achieved in acute toxicity test and its relationship to dose level and the time course of the toxicity study. Acute hepatotoxicity study and its relevant toxicokinetic study in mice were performed using acetarninophen (AA) as a model compound. The correlation between acute hepatotoxicity indices and toxicokinetic parameters following intraperitoneally administration of various dosages of AA in mice was evaluated and discussed minutely in the text. Based on these studies, single-dose toxicity testing of AA including kinetic studies was evaluated in ICR mice for 7 days and interpreted in the text. Our results from the integration of toxicokinetic monitoring into single-dose toxicity study enable to elucidate the relation of the exposure achieved in toxicity study to toxicological findings and assist in the selection of appropriate dose levels for use in repeated-dose toxicity or later studies.

• Journal of Korean Society for Quality Management
• /
• v.29 no.1
• /
• pp.184-190
• /
• 2001

Industrial structure is more developed, the economical value of human resources and the cases which risks worker's Health & Safety is expended. The Safety & Health issues are focused on elements of control for management activity simultaneously with work environment as well as the risk elements which risks worker's life and body. The activity for combination of basic management System and Safety & Health management is progressing with active discussion in ILO, BS 8800 is specified the guidance of Occupational Safety & Health Management System in UK. 1996. This research refers to BS 8800:1996, specification as a basic model, and introduce of the result of certification development result in Occupational Safety & Health management System with in ISO 14001 Environmental System Standards & ISO 9001 Quality Management System Standards and Systemic Factors. Through this applicability and efficiency evaluation, we make an effort to support and to improve the specification. Also applicability evaluation of Occupational Safety & Health management System and the specification developed for the purpose of the third party certification is applied with expending in industry, and the method is presented through the case which is required to support for method review and activities.

• Proceedings of the KSRS Conference
• /
• 1998.09a
• /
• pp.280.2-286
• /
• 1998

Flood is the main natural disaster mostly in the world. It is a care problem to prevent flood disaster generally. The frequency of flood disaster is high and the distributing field is wide, the 50 percent population and 70 percent properties distribute at the threaten field of flood disaster in China. Flood disaster has caused a huge amount of economical losses and these losses have an increasing trend. Along with the development of reducing natural disaster action, it has become one of the most attentive problems for monitoring flood, preventing flood and forecasting flood efficiently. Remote sensing has the characteristics of large spatial observing areas, wide spectrum ranges, and imaging far away from the targets, imaging capabilities all weather. Spatial remote sensing information, which records the full, processes of the disaster's occurrence and development in real-time. It is a scientific basis for management, planning and decision-making. Through systemic analyzing the RS monitoring theory, based on compounding RS information, the technology and method of monitoring flood disaster are studied.

• Proceedings of the Korean Society of Developmental Biology Conference
• /
• 2001.02a
• /
• pp.27-31
• /
• 2001

This study examined the extent of mammary excretion and placental transfer of bisphenol A in rats. Bisphenol A was given by simultaneous i.v. bolus injection plus infusion to steady-state at low, medium and high doses. The steady-state serum levels of bisphenol A were linearly increased with increasing the dosing rate. The systemic clearance (mean range, 119.2-154.1 ml/min/kg) remained unaltered over the dosing rate studied. The levels of bisphenol A in milk exceeded those in serum, with the steady-state milk to serum concentration ratio being 2.4-2.7. The steady-state milk levels of bisphenol A were also increased linearly with increasing the infusion rate. In a separate study, the kinetic disposition of bisphenol A in the rat maternal-fetal unit was studied in pregnant rats. After i.v. injection, bisphenol A concentration in the maternal serum declined biexponentially. Bisphenol A was rapidly distributed into placenta, fetus and amniotic fluid, with maximum concentrations in these tissues achieved within 1 hr of injection. The decline of bisphenol A in placenta, fetus and amniotic fluid paralleled that of maternal serum. A simultaneous computer simulation showed that the observed concentrations were well represented by a 5-compartmental model consisting of the maternal central, placenta, fetus, amniotic fluid, and maternal tissue compartments.