• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.4A
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• pp.412-420
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• 2006

With the appearance of various types of traffic services in communication networks, a study on QoS(Quality of Service) packet scheduling mechanisms which can support differentiated service to each traffic service becomes very important. To meet this requirement, IEEE 802.11 Working Group established the IEEE 802.11e MAC protocol which categorizes every traffic services into 4 access categories(AC) and provides the differentiated service to each AC. In addition, the physical layer of IEEE 802.11a/g standards provide up to 54 Mbps transmission rate per one wireless LAN terminal. However, since the radio resource is hardly limited in wireless channel, it is necessary to find an efficient packet scheduling scheme to maximize the transmission efficiency. Therefore, in this paper, we proposed a new packet scheduling scheme that can enhance the total throughput by setting different contention windows(CW) of CSMA-CA channel access scheme to each wireless LAN terminal according its current channel states. Numerical results derived from using NS-2 network simulator have shown that our proposed packet scheduling scheme can enhance the performance of IEEE 802.11e more and more.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.7B
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• pp.469-476
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• 2008

In this paper we analyze the packet interference probability and the aggregated throughput of a WPAN in which a number of Bluetooth piconets share the ISM band with WLANS. Using an Adaptive Frequency Hopping algorithm, when the AFH is employed, the number of hops available to the Bluetooth piconets varies depending on the number of independent WLANs within the piconet's radio range. Using a packet collision model in a piconet cluster, we give an analysis of the packet interference probability and the aggregated throughput as a function of the available hops for the AFH algorithm. We also present an analytical model of packet interference with multi-path fading channel in a cluster of piconets. Through analysis, we obtain the packet collision probability and aggregated throughput assuming capture effect. Numerical examples are given to demonstrate the effect of various Parameters such as capture ratio, Rice factor and cluster size on the system performance.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.421-425
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• 2005

The increasing number of wireless subscribers who can use internet service any time and any place have caused wireless communications networks to flourish. However, since total communication channel bandwidth for wireless communications is limited, it is very important to find the solution for maximizing the channel utilization. Thus, in this work we propose a QoS packet scheduler for IEEE 802.11e EDCA scheme which is able to maximize the channel throughput with changing the CW value considering wireless channel condition. This proposed scheme is evaluated with NS-2 network simulator under various environments and it is easily shown from the numerical results that the proposed scheme provides better performance than that of the original IEEE 802.11e scheme.

• Journal of KIISE:Information Networking
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• v.37 no.5
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• pp.386-395
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• 2010

Widespread deployment of infrastructure WLANs has made Wi-Fi an integral part of today's Internet access technology. Despite its crucial role in affecting end-to-end performance, past research has focused on MAC protocol enhancement, analysis, and simulation-based performance evaluation without sufficiently considering a misbehavior stemming from capture effect. It is well known that the capture effect occurs frequently in wireless environment and incurs throughput unfairness between nodes. In this paper, we propose a novel Fair MAC algorithm which achieves fairness even under physically unfair environment. While satisfying the fairness, the proposed algorithm maximizes the system throughput. Extensive simulation results show that the proposed Fair MAC algorithm substantially improves fairness without throughput reduction.

• Mass Spectrometry Letters
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• v.4 no.3
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• pp.47-50
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• 2013

An ultra-fast generic LC-MS/MS method was developed for high-throughput quantification of discovery pharmacokinetic (PK) samples and its reliability was verified. The method involves a simple protein precipitation for sample preparation and the analysis by ultra-fast generic LC-MS/MS with the ballistic gradient program and selected reaction monitoring (SRM) mode. Approximately 290 new chemical entities (NCEs) (over 10,000 samples) from 5 therapeutic programs were analyzed. The calibration curves showed good linearity in the concentration range of 1, 2 or 5 to 2000 ng/mL. No significant ion suppression was observed in the elution region of all the NCEs. When approximately 300 plasma samples were continuously analyzed, the peak area of internal standard was constant and reproducible. In the repeated analysis of samples, the plasma concentrations and the area under the curve (AUC) were consistent with the results from the first analysis. These results showed that the present ultra-fast generic LC-MS/MS method is reliable in terms of selectivity, sensitivity, and reproducibility and could be useful for high-throughput quantification and other bioanalysis in drug discovery.

• Biomolecules & Therapeutics
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• v.18 no.2
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• pp.152-158
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• 2010

Melanin concentrating hormone is a neuropeptide highly expressed in the brain that regulates several physiological functions mediated by receptors in the G-protein coupled receptor family, especially plays an important role in the complex regulation of energy balance and body weight mediated by the melanin concentrating hormone receptor subtype 1 (MCH1). Compelling pharmacological evidence implicating MCH1 signaling in the regulation of food intake and energy expenditure has generated a great deal of interest by pharmaceutical companies as MCH1 antagonists may have potential therapeutic benefit in the treatment of obesity and metabolic syndrome. Although fluorescence-based calcium mobilization assay platform has been one of the most widely accepted tools for receptor research and drug discovery, fluorescence interference and shallow assay window limit their application in high throughput screening and have led to a growing interest in alternative, luminescence-based technologies. Herein, a luminescence-based functional assay system for the MCH1 receptor was developed and validated with the mitochondrial targeted aequorin. Aequorin based functional assay system for MCH1 presented excellent Z' factor (0.8983) and high signal-to-noise ratio (141.9). The nonpeptide MCH1 receptor antagonist, SNAP 7941 and GSK 803430, exhibited $IC_{50}$ values of 0.62 ${\pm}$ 0.11 and 12.29 ${\pm}$ 2.31 nM with excellent correlation coefficient. These results suggest that the aequorin based assay system for MCH1 is a strong alternative to the traditional GPCR related tools such as radioligand binding experiments and fluorescence functional determinations for the compound screening and receptor research.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.3 no.4
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• pp.385-398
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• 2009

This paper aims to find a suitable solution to joint allocation of sub-channel and transmit power for multiple users in an IEEE 802.16e OFDMA/TDD cellular system. We propose the FASA (Fairness insured Aggressive Sub-channel Allocation) algorithm, which is a dynamic channel allocation algorithm that considers all of the users' channel state information conditionally in order to maximize throughput while taking into account fairness. A dynamic power allocation algorithm, i.e., an improved CHC algorithm, is also proposed in combination with the FASA algorithm. It collects the extra downlink transmit power and re-allocates it to other potential users. Simulation results show that the joint allocation scheme with the improved CHC power allocation algorithm provides an additional increase of sector throughput while simultaneously enhancing fairness. Four frames of time delay for CQI feedback and scheduling are considered. Furthermore, by addressing the difference between uplink and downlink scheduling in an IEEE 802.16e OFDMA TDD system, we can employ the uplink channel information directly via channel sounding, resulting in more accurate uplink dynamic resource allocation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.11
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• pp.3008-3025
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• 2012

In this paper, the downlink resource allocation of OFDMA system with decode-and-forward (DF) relaying is investigated. A non-convex optimization problem maximizing system throughput with users' satisfaction constraints is formulated with joint relay selection, subcarrier assignment and power allocation. We first transform it to a standard convex problem and then solve it by dual decomposition. In particular, an Optimal resource allocation scheme With Time-sharing (OWT) is proposed with combination of relay selection, subcarrier allocation and power control. Due to its poor adaption to the fast-varying environment, an improved version with subcarrier Monopolization (OWM) is put forward, whose performance promotes about 20% compared with that of OWT in the fast-varying vehicular environment. In fact, OWM is the special case of OWT with binary time-sharing factor and OWT can be seen as the tight upper bound of the OWM. To the best of our knowledge, such algorithms and their relation have not been accurately investigated in cooperative OFDMA networks in the literature. Simulation results show that both the system throughput and the users' satisfaction of the proposed algorithms outperform the traditional ones.

• Journal of Satellite, Information and Communications
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• v.10 no.1
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• pp.12-16
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• 2015

In this paper, we introduce a wireless package system based on the amateur radio HR(HAM Radio) and satellite communication as a novel wireless disaster communication system and have configured a interference scenario receiving interference from adjacent base stations and D2D groups in the disaster network. In such interference scenarios, we propose a frequency re-allocation method to avoid interference and communicate with disaster networks by securing the channel capacity required between D2D terminals. As a result of computer simulation, we can find the proposed method has improved BED performance of a gain of 1.5dB and overall system throughput than conventional methods.

• 한국정보통신설비학회:학술대회논문집
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• 2009.08a
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• pp.314-319
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• 2009

In this paper, the network performance of a turbo coded optical code division multiple access (COMA) system with cross-layer, which is between physical and network layers, concept is analyzed and simulated We consider physical and MAC layers in a cross-layer concept. An intensity-modulated/direct-detection (IM/DD) optical system employing pulse position modulation (PPM) is considered In order to increase the system performance, turbo codes composed of parallel concatenated convolutional codes (PCCCs) is utilized. The network performance is evaluated in terms of bit error probability (BEP). From the simulation results, it is demonstrated that turbo coding offers considerable coding gain with reasonable encoding and decoding complexity. Also, it is confirmed that the performance of such an optical COMA network can be substantially improved by increasing the interleaver length and the number of iterations in the decoding process. The results of this paper can be applied to implement the indoor optical wireless LANs.